𝕏

Task 55226730

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_476_1
Workunit 26226951
Created 28 Jun 2024, 6:10:30 UTC
Sent 29 Jun 2024, 6:07:36 UTC
Report deadline 2 Jul 2024, 6:07:36 UTC
Received 30 Jun 2024, 23:43:46 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213646
Run time 2 hours 9 min 42 sec
CPU time 1 hours 50 min 42 sec
Validate state Valid
Credit 43.58
Device peak FLOPS 3.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.76 MB
Peak swap size 32.79 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_476.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_476_1_r1801054663_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_476_1_r1801054663_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.008075
     * GNaL_b in INaL: 0.005120
     * Gto_b in Ito: 0.095600
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032702
     * GKs_b in IKs: 0.001805
     * GK1_b in IK1: 0.174463
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 74.101249
     * GKb_b in IKb: 0.003905
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.023913
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 300.000000
     * CL_0 in membrane: 10000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13583129, states[0] = -94.353037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27966169, states[0] = -94.334937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40867521, states[0] = -94.363130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54785594, states[0] = -94.341078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67308425, states[0] = -94.348284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81058425, states[0] = -94.373567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94136213, states[0] = -94.352356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106025898, states[0] = -94.379342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117761573, states[0] = -94.356905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 131681711, states[0] = -94.367329, states[40]= 0.000001
Saving checkpoint... 
Iteration: 145344510, states[0] = -94.062528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158423758, states[0] = -94.358740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172364875, states[0] = -94.362120, states[40]= 0.000001
Saving checkpoint... 
Iteration: 186353631, states[0] = -94.376094, states[40]= 0.000001
Saving checkpoint... 
Iteration: 198692291, states[0] = -94.359699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213304358, states[0] = -94.359923, states[40]= 0.000001
Saving checkpoint... 
Iteration: 227741005, states[0] = -94.361076, states[40]= 0.000001
Saving checkpoint... 
Iteration: 239188287, states[0] = -94.360299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252923245, states[0] = -94.360616, states[40]= 0.000001
Saving checkpoint... 
Iteration: 267561279, states[0] = -94.361828, states[40]= 0.000001
Saving checkpoint... 
Iteration: 279646976, states[0] = -94.360863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292071184, states[0] = -94.365137, states[40]= 0.000001
Saving checkpoint... 
Iteration: 305856896, states[0] = -94.387175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318002370, states[0] = -94.360335, states[40]= 0.000001
Saving checkpoint... 
Iteration: 332674312, states[0] = -94.361203, states[40]= 0.000001
Saving checkpoint... 
Iteration: 347182714, states[0] = -94.363987, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_476.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_476_1_r1801054663_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_476_1_r1801054663_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.008075
     * GNaL_b in INaL: 0.005120
     * Gto_b in Ito: 0.095600
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032702
     * GKs_b in IKs: 0.001805
     * GK1_b in IK1: 0.174463
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 74.101249
     * GKb_b in IKb: 0.003905
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.023913
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 300.000000
     * CL_0 in membrane: 10000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 347182714
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.363987 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 357970434, states[0] = -94.360268, states[40]= 0.000001
Saving checkpoint... 
Iteration: 372061451, states[0] = -94.364981, states[40]= 0.000001
Saving checkpoint... 
Iteration: 384155229, states[0] = -94.359945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395584758, states[0] = -94.358750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408571234, states[0] = -94.359533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420688880, states[0] = -94.379314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433208270, states[0] = -94.359624, states[40]= 0.000001
Saving checkpoint... 
Iteration: 446692965, states[0] = -94.369332, states[40]= 0.000001
Saving checkpoint... 
Iteration: 460165282, states[0] = -8.562895, states[40]= 0.000444
Saving checkpoint... 
Iteration: 473871495, states[0] = -94.359383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485882695, states[0] = -94.386493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499045465, states[0] = -94.359415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512874562, states[0] = -94.359916, states[40]= 0.000001
Saving checkpoint... 
Iteration: 524201849, states[0] = -94.359469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536995649, states[0] = -94.365034, states[40]= 0.000001
Saving checkpoint... 
Iteration: 547982501, states[0] = -94.359537, states[40]= 0.000001
Saving checkpoint... 
Iteration: 563620214, states[0] = -94.358952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576274046, states[0] = -94.377410, states[40]= 0.000001
Saving checkpoint... 
Iteration: 590642330, states[0] = -94.371964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602490050, states[0] = -94.361020, states[40]= 0.000001
Saving checkpoint... 
Iteration: 617275147, states[0] = -94.362275, states[40]= 0.000001
Saving checkpoint... 
Iteration: 631693382, states[0] = -94.368628, states[40]= 0.000001
Saving checkpoint... 
Iteration: 644085067, states[0] = -94.358902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656883930, states[0] = -94.365862, states[40]= 0.000001
Saving checkpoint... 
Iteration: 667886662, states[0] = -94.359299, states[40]= 0.000001
Saving checkpoint... 
Iteration: 679687741, states[0] = -94.359494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692364543, states[0] = -94.361393, states[40]= 0.000001
Saving checkpoint... 
Iteration: 705192220, states[0] = -21.437542, states[40]= 0.002805
Saving checkpoint... 
Iteration: 718408724, states[0] = -94.358399, states[40]= 0.000001
Saving checkpoint... 
Iteration: 731096527, states[0] = -94.381450, states[40]= 0.000001
Saving checkpoint... 
Iteration: 745426391, states[0] = -94.243065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759981928, states[0] = -94.359632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773049234, states[0] = -94.358562, states[40]= 0.000001
Saving checkpoint... 
Iteration: 785958369, states[0] = -94.384435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800638366, states[0] = -94.370440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812920704, states[0] = -94.358669, states[40]= 0.000001
Saving checkpoint... 
Iteration: 825912440, states[0] = -94.384966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839687506, states[0] = -94.358888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852182091, states[0] = -94.362099, states[40]= 0.000001
Saving checkpoint... 
Iteration: 865235214, states[0] = -42.534348, states[40]= 0.001105
Saving checkpoint... 
Iteration: 877284915, states[0] = -94.361223, states[40]= 0.000001
Saving checkpoint... 
Iteration: 890243305, states[0] = -48.972405, states[40]= 0.000461
Saving checkpoint... 
Iteration: 904440589, states[0] = -94.358309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920351271, states[0] = -94.085089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933135847, states[0] = -94.357824, states[40]= 0.000001
Saving checkpoint... 
Iteration: 946068272, states[0] = -94.381365, states[40]= 0.000001
Saving checkpoint... 
Iteration: 961916682, states[0] = -94.364314, states[40]= 0.000001
Saving checkpoint... 
Iteration: 975688905, states[0] = -94.377225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988853358, states[0] = -94.357426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003901664, states[0] = -94.357399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017456910, states[0] = -94.359627, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1031506182, states[0] = -94.370451, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1045321764, states[0] = -93.981382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059878125, states[0] = -94.358338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074163587, states[0] = -94.357351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087683658, states[0] = -94.358337, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1100840221, states[0] = -94.384145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113269511, states[0] = -94.356995, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1126648481, states[0] = -94.367490, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1142240489, states[0] = -94.360545, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1154314459, states[0] = -94.357211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167896235, states[0] = -94.357386, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1181871324, states[0] = -94.364035, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1193945263, states[0] = -94.356710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207332208, states[0] = -94.359654, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1220093047, states[0] = 19.483479, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1232445603, states[0] = -94.358876, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1245717266, states[0] = -94.378927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259151428, states[0] = -94.356640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272616183, states[0] = -94.357903, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1285986525, states[0] = -94.382001, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1299630351, states[0] = -94.357069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312564806, states[0] = -94.357976, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1325236754, states[0] = -43.714326, states[40]= 0.000949
Saving checkpoint... 
Iteration: 1338260762, states[0] = -94.356153, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1352314599, states[0] = -94.359224, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1364967104, states[0] = -94.357322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376238410, states[0] = -94.375296, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1389472367, states[0] = -94.356516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403086168, states[0] = -94.356120, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1415299319, states[0] = -93.879444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427852289, states[0] = -94.356516, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1442945977, states[0] = -94.356231, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1455010092, states[0] = 27.953754, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_476.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_476_1_r1801054663_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_476_1_r1801054663_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.008075
     * GNaL_b in INaL: 0.005120
     * Gto_b in Ito: 0.095600
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032702
     * GKs_b in IKs: 0.001805
     * GK1_b in IK1: 0.174463
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 74.101249
     * GKb_b in IKb: 0.003905
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.023913
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 300.000000
     * CL_0 in membrane: 10000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1455010092
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 27.953754 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1467625343, states[0] = -94.357128, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1480674468, states[0] = -94.373573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493162248, states[0] = -94.355673, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.232850
 - CaMKt in component CaMK (millimolar): 0.000859
 - cass in component intracellular_ions (millimolar): 0.000093
 - nai in component intracellular_ions (millimolar): 7.480726
 - nass in component intracellular_ions (millimolar): 7.480867
 - ki in component intracellular_ions (millimolar): 144.391312
 - kss in component intracellular_ions (millimolar): 144.391301
 - cansr in component intracellular_ions (millimolar): 1.709428
 - cajsr in component intracellular_ions (millimolar): 1.710201
 - cai in component intracellular_ions (millimolar): 0.000098
 - m in component INa (dimensionless): 0.003871
 - hf in component INa (dimensionless): 0.867897
 - hs in component INa (dimensionless): 0.867897
 - j in component INa (dimensionless): 0.867897
 - hsp in component INa (dimensionless): 0.703446
 - jp in component INa (dimensionless): 0.867897
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.711156
 - hLp in component INaL (dimensionless): 0.518236
 - a in component Ito (dimensionless): 0.000652
 - iF in component Ito (dimensionless): 0.999853
 - iS in component Ito (dimensionless): 0.999850
 - ap in component Ito (dimensionless): 0.000332
 - iFp in component Ito (dimensionless): 0.999853
 - iSp in component Ito (dimensionless): 0.999853
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999987
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003926
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000006
 - xs1 in component IKs (dimensionless): 0.002860
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997507
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:43:23 (30823): called boinc_finish(0)

</stderr_txt>
]]>


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