𝕏

Task 55226728

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_376_1
Workunit 26226950
Created 28 Jun 2024, 6:10:30 UTC
Sent 29 Jun 2024, 6:07:36 UTC
Report deadline 2 Jul 2024, 6:07:36 UTC
Received 30 Jun 2024, 2:10:33 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213646
Run time 2 hours 26 min 6 sec
CPU time 1 hours 56 min 51 sec
Validate state Valid
Credit 45.74
Device peak FLOPS 3.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.97 MB
Peak swap size 33.04 GB
Peak disk usage 0.04 MB

Stderr output

<core_client_version>8.0.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_376.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_376_1_r2046283748_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_376_1_r2046283748_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 91.561615
     * GNaL_b in INaL: 0.005610
     * Gto_b in Ito: 0.074088
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032819
     * GKs_b in IKs: 0.002135
     * GK1_b in IK1: 0.163435
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 69.254525
     * GKb_b in IKb: 0.003891
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036784
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 300.000000
     * CL_0 in membrane: 10000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 6361795, states[0] = -94.275996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 18373124, states[0] = -94.225592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29096803, states[0] = -94.220360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39519018, states[0] = -94.223743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49488465, states[0] = -94.228699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59316656, states[0] = -94.233610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68475992, states[0] = -94.237849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79782289, states[0] = -94.242723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92069931, states[0] = -94.252233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103083655, states[0] = -94.249355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113984057, states[0] = -94.250833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126234831, states[0] = -94.273842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137975281, states[0] = -94.254773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148117895, states[0] = -94.255313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159914047, states[0] = -94.256356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171569110, states[0] = -94.269361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183633511, states[0] = -94.256541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195625167, states[0] = -94.267914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207239494, states[0] = -94.261516, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_376.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_376_1_r2046283748_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_376_1_r2046283748_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 91.561615
     * GNaL_b in INaL: 0.005610
     * Gto_b in Ito: 0.074088
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032819
     * GKs_b in IKs: 0.002135
     * GK1_b in IK1: 0.163435
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 69.254525
     * GKb_b in IKb: 0.003891
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036784
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 300.000000
     * CL_0 in membrane: 10000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 207239494
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.261516 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 216273938, states[0] = -94.277181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226529301, states[0] = -94.271294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237471790, states[0] = -94.260209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247887075, states[0] = -94.258481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258128107, states[0] = -94.257938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267750916, states[0] = -94.258979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277434413, states[0] = -94.260526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286968630, states[0] = -94.264559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295156213, states[0] = -4.346863, states[40]= 0.000276
Saving checkpoint... 
Iteration: 303285447, states[0] = -94.257694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311651281, states[0] = -94.269110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321298831, states[0] = -94.276732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329847033, states[0] = -94.258131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339347142, states[0] = -94.257607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347879440, states[0] = -94.258424, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_376.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_376_1_r2046283748_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_376_1_r2046283748_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 91.561615
     * GNaL_b in INaL: 0.005610
     * Gto_b in Ito: 0.074088
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032819
     * GKs_b in IKs: 0.002135
     * GK1_b in IK1: 0.163435
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 69.254525
     * GKb_b in IKb: 0.003891
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036784
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 300.000000
     * CL_0 in membrane: 10000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 347879440
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.258424 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 357770961, states[0] = -94.258754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368070770, states[0] = -94.257883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379469029, states[0] = -94.257594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389230623, states[0] = -94.257370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397888816, states[0] = -94.258242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407556392, states[0] = -94.259528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419542471, states[0] = -94.257532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430420581, states[0] = -94.130024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440337959, states[0] = -93.931826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452010749, states[0] = -94.263620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463425552, states[0] = -94.257073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474331436, states[0] = -94.257159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486020386, states[0] = -94.283710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496244890, states[0] = -94.277599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507111104, states[0] = -94.262394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518272199, states[0] = -94.257044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529134196, states[0] = -94.256835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540506727, states[0] = -94.219432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551631576, states[0] = -94.268693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563147951, states[0] = -94.257077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573986538, states[0] = -94.256609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584546064, states[0] = -94.256970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594858955, states[0] = -94.257270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608413663, states[0] = -94.256583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621002285, states[0] = -94.283679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632221593, states[0] = -94.260971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643232330, states[0] = -94.256667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651947731, states[0] = -94.263659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667759987, states[0] = -94.257744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680344335, states[0] = -93.952820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691473518, states[0] = -94.271342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704100916, states[0] = -94.256212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714178338, states[0] = -94.256223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725459907, states[0] = -94.179159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737837398, states[0] = -94.257235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748828505, states[0] = -94.255965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759372494, states[0] = -94.256209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771581258, states[0] = -94.268868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781998346, states[0] = -94.262622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793993585, states[0] = -94.255852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806343114, states[0] = -94.273984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817401471, states[0] = -94.259011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829274504, states[0] = -94.255891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841045496, states[0] = -94.281856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852651628, states[0] = -94.257544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866022766, states[0] = -94.282344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876936400, states[0] = -94.263020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888168701, states[0] = -94.255919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899542596, states[0] = -94.255879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910475984, states[0] = -94.194141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922517419, states[0] = -94.257961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934099207, states[0] = -94.255417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945574474, states[0] = -94.251906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958010796, states[0] = -94.255993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969480296, states[0] = -94.255578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981913500, states[0] = -94.262941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993572962, states[0] = -94.255154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005872916, states[0] = -94.284318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017615030, states[0] = -94.257141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028346820, states[0] = -94.255196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040534063, states[0] = -94.233967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052417051, states[0] = -94.258100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063810705, states[0] = -94.254875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077194714, states[0] = -94.259663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088142943, states[0] = -94.255273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101766285, states[0] = -94.264565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114833653, states[0] = -94.255444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126765745, states[0] = -94.264487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138814168, states[0] = -94.254617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150664642, states[0] = -94.272920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163496538, states[0] = -94.254606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175992635, states[0] = -94.281988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188136895, states[0] = -94.254939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199684248, states[0] = -94.254986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209514813, states[0] = -94.254781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221000504, states[0] = -94.281653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234804006, states[0] = -94.254996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248643355, states[0] = -94.254250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261864916, states[0] = -94.262605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274581494, states[0] = -94.254621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285546327, states[0] = -94.239179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295426106, states[0] = -94.135273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308795956, states[0] = -94.254028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320378388, states[0] = -94.046225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334249215, states[0] = -94.254128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345853929, states[0] = -94.283153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357049378, states[0] = -94.260083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371920813, states[0] = -94.261503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384152553, states[0] = -94.253892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397164449, states[0] = -94.258825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412316201, states[0] = -94.257542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426389193, states[0] = -94.270725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441035866, states[0] = -94.280035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454553763, states[0] = -94.253972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465521571, states[0] = -94.225573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476772193, states[0] = -94.263182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491735976, states[0] = -94.263689, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.130298
 - CaMKt in component CaMK (millimolar): 0.000834
 - cass in component intracellular_ions (millimolar): 0.000092
 - nai in component intracellular_ions (millimolar): 7.578664
 - nass in component intracellular_ions (millimolar): 7.578801
 - ki in component intracellular_ions (millimolar): 144.301236
 - kss in component intracellular_ions (millimolar): 144.301225
 - cansr in component intracellular_ions (millimolar): 1.683836
 - cajsr in component intracellular_ions (millimolar): 1.684461
 - cai in component intracellular_ions (millimolar): 0.000097
 - m in component INa (dimensionless): 0.003912
 - hf in component INa (dimensionless): 0.865953
 - hs in component INa (dimensionless): 0.865953
 - j in component INa (dimensionless): 0.865953
 - hsp in component INa (dimensionless): 0.699919
 - jp in component INa (dimensionless): 0.865953
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.708335
 - hLp in component INaL (dimensionless): 0.514819
 - a in component Ito (dimensionless): 0.000657
 - iF in component Ito (dimensionless): 0.999851
 - iS in component Ito (dimensionless): 0.999847
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999851
 - iSp in component Ito (dimensionless): 0.999850
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999987
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003734
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000006
 - xs1 in component IKs (dimensionless): 0.002858
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997533
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:58:35 (8700): called boinc_finish(0)

</stderr_txt>
]]>