𝕏

Task 55226725

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_276_0
Workunit 26226949
Created 28 Jun 2024, 6:10:30 UTC
Sent 29 Jun 2024, 6:07:36 UTC
Report deadline 2 Jul 2024, 6:07:36 UTC
Received 30 Jun 2024, 23:44:24 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213646
Run time 2 hours 10 min 4 sec
CPU time 1 hours 50 min 43 sec
Validate state Valid
Credit 43.67
Device peak FLOPS 3.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.89 MB
Peak swap size 32.99 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_276.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_276_0_r825248503_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_276_0_r825248503_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 92.331028
     * GNaL_b in INaL: 0.006450
     * Gto_b in Ito: 0.076240
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.029976
     * GKs_b in IKs: 0.002068
     * GK1_b in IK1: 0.157307
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 67.518163
     * GKb_b in IKb: 0.003846
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.041223
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 300.000000
     * CL_0 in membrane: 10000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13986500, states[0] = -94.162242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27446576, states[0] = -94.162401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39081420, states[0] = -94.160056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53989041, states[0] = -94.166987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67500019, states[0] = -94.178302, states[40]= 0.000001
Saving checkpoint... 
Iteration: 80605696, states[0] = -94.082923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95385528, states[0] = -25.782693, states[40]= 0.009167
Saving checkpoint... 
Iteration: 108235162, states[0] = -94.181334, states[40]= 0.000001
Saving checkpoint... 
Iteration: 121152384, states[0] = -94.225913, states[40]= 0.000001
Saving checkpoint... 
Iteration: 133986682, states[0] = -94.182828, states[40]= 0.000001
Saving checkpoint... 
Iteration: 147352028, states[0] = -94.191895, states[40]= 0.000001
Saving checkpoint... 
Iteration: 160044330, states[0] = 34.156624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172451379, states[0] = -94.191568, states[40]= 0.000001
Saving checkpoint... 
Iteration: 186367618, states[0] = -94.220688, states[40]= 0.000001
Saving checkpoint... 
Iteration: 200460982, states[0] = -75.092668, states[40]= 0.000013
Saving checkpoint... 
Iteration: 214036573, states[0] = -94.185452, states[40]= 0.000001
Saving checkpoint... 
Iteration: 228317996, states[0] = -94.186258, states[40]= 0.000001
Saving checkpoint... 
Iteration: 242811324, states[0] = -94.188872, states[40]= 0.000001
Saving checkpoint... 
Iteration: 256555549, states[0] = -94.213801, states[40]= 0.000001
Saving checkpoint... 
Iteration: 270207569, states[0] = -20.853448, states[40]= 0.006263
Saving checkpoint... 
Iteration: 286187575, states[0] = -94.229502, states[40]= 0.000001
Saving checkpoint... 
Iteration: 298540827, states[0] = -94.185848, states[40]= 0.000001
Saving checkpoint... 
Iteration: 312730966, states[0] = -94.189514, states[40]= 0.000001
Saving checkpoint... 
Iteration: 326280852, states[0] = -94.225350, states[40]= 0.000001
Saving checkpoint... 
Iteration: 339133176, states[0] = -94.185614, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_276.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_276_0_r825248503_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_276_0_r825248503_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 92.331028
     * GNaL_b in INaL: 0.006450
     * Gto_b in Ito: 0.076240
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.029976
     * GKs_b in IKs: 0.002068
     * GK1_b in IK1: 0.157307
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 67.518163
     * GKb_b in IKb: 0.003846
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.041223
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 300.000000
     * CL_0 in membrane: 10000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 339133176
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.185614 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 350166852, states[0] = -5.836102, states[40]= 0.000593
Saving checkpoint... 
Iteration: 362717543, states[0] = -94.189492, states[40]= 0.000001
Saving checkpoint... 
Iteration: 372998807, states[0] = -94.187461, states[40]= 0.000001
Saving checkpoint... 
Iteration: 384956389, states[0] = -94.186797, states[40]= 0.000001
Saving checkpoint... 
Iteration: 398828518, states[0] = -94.185320, states[40]= 0.000001
Saving checkpoint... 
Iteration: 410267350, states[0] = 23.564308, states[40]= 0.035407
Saving checkpoint... 
Iteration: 421904366, states[0] = -94.202425, states[40]= 0.000001
Saving checkpoint... 
Iteration: 435661460, states[0] = -94.149863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448591361, states[0] = -94.185308, states[40]= 0.000001
Saving checkpoint... 
Iteration: 462511274, states[0] = -94.191261, states[40]= 0.000001
Saving checkpoint... 
Iteration: 476238230, states[0] = -94.226760, states[40]= 0.000001
Saving checkpoint... 
Iteration: 489899131, states[0] = -94.186293, states[40]= 0.000001
Saving checkpoint... 
Iteration: 503896376, states[0] = -94.184930, states[40]= 0.000001
Saving checkpoint... 
Iteration: 514622102, states[0] = -94.185653, states[40]= 0.000001
Saving checkpoint... 
Iteration: 528590377, states[0] = -94.185011, states[40]= 0.000001
Saving checkpoint... 
Iteration: 541084766, states[0] = -94.232572, states[40]= 0.000001
Saving checkpoint... 
Iteration: 554712543, states[0] = -94.185671, states[40]= 0.000001
Saving checkpoint... 
Iteration: 567296606, states[0] = -94.193832, states[40]= 0.000001
Saving checkpoint... 
Iteration: 582026103, states[0] = -94.198903, states[40]= 0.000001
Saving checkpoint... 
Iteration: 594883831, states[0] = -94.185866, states[40]= 0.000001
Saving checkpoint... 
Iteration: 608574370, states[0] = -94.184731, states[40]= 0.000001
Saving checkpoint... 
Iteration: 621900104, states[0] = -94.201790, states[40]= 0.000001
Saving checkpoint... 
Iteration: 633933774, states[0] = -94.184446, states[40]= 0.000001
Saving checkpoint... 
Iteration: 645786548, states[0] = -94.214916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659969525, states[0] = -94.185806, states[40]= 0.000001
Saving checkpoint... 
Iteration: 672915680, states[0] = -94.186849, states[40]= 0.000001
Saving checkpoint... 
Iteration: 686011371, states[0] = -94.233582, states[40]= 0.000001
Saving checkpoint... 
Iteration: 699444330, states[0] = -94.184664, states[40]= 0.000001
Saving checkpoint... 
Iteration: 711200722, states[0] = -94.227519, states[40]= 0.000001
Saving checkpoint... 
Iteration: 724550218, states[0] = -94.184738, states[40]= 0.000001
Saving checkpoint... 
Iteration: 737508823, states[0] = -94.190258, states[40]= 0.000001
Saving checkpoint... 
Iteration: 752089589, states[0] = -94.196899, states[40]= 0.000001
Saving checkpoint... 
Iteration: 765081597, states[0] = 23.808731, states[40]= 0.000001
Saving checkpoint... 
Iteration: 776813067, states[0] = -94.203586, states[40]= 0.000001
Saving checkpoint... 
Iteration: 790002697, states[0] = 24.132422, states[40]= 1.149130
Saving checkpoint... 
Iteration: 803999159, states[0] = -94.183824, states[40]= 0.000001
Saving checkpoint... 
Iteration: 815579130, states[0] = -94.028035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829571719, states[0] = -94.184378, states[40]= 0.000001
Saving checkpoint... 
Iteration: 843131731, states[0] = -94.185054, states[40]= 0.000001
Saving checkpoint... 
Iteration: 855884649, states[0] = -94.229527, states[40]= 0.000001
Saving checkpoint... 
Iteration: 867641231, states[0] = -94.188328, states[40]= 0.000001
Saving checkpoint... 
Iteration: 881202171, states[0] = -94.226816, states[40]= 0.000001
Saving checkpoint... 
Iteration: 894614003, states[0] = -94.184207, states[40]= 0.000001
Saving checkpoint... 
Iteration: 911071436, states[0] = -94.231565, states[40]= 0.000001
Saving checkpoint... 
Iteration: 923762533, states[0] = -94.183376, states[40]= 0.000001
Saving checkpoint... 
Iteration: 937499799, states[0] = -94.189612, states[40]= 0.000001
Saving checkpoint... 
Iteration: 953422430, states[0] = -94.183701, states[40]= 0.000001
Saving checkpoint... 
Iteration: 967690324, states[0] = -94.187484, states[40]= 0.000001
Saving checkpoint... 
Iteration: 980070382, states[0] = 27.507088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992792059, states[0] = -94.186524, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1005797984, states[0] = -94.216361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018924302, states[0] = -94.182993, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1031030019, states[0] = -94.232038, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1044085930, states[0] = -94.182966, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1057066893, states[0] = -94.196225, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1070223365, states[0] = -22.614220, states[40]= 0.009337
Saving checkpoint... 
Iteration: 1083618416, states[0] = -94.182887, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1095156523, states[0] = -1.581437, states[40]= 0.000395
Saving checkpoint... 
Iteration: 1108891882, states[0] = -94.182651, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1122952429, states[0] = -94.184925, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1135284008, states[0] = 28.735190, states[40]= 0.007787
Saving checkpoint... 
Iteration: 1149861841, states[0] = -94.183727, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1164249906, states[0] = -94.182658, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1175740038, states[0] = -94.197378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189287222, states[0] = -94.182606, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1202542684, states[0] = -94.188111, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1216185139, states[0] = -94.226281, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1229539646, states[0] = -94.182816, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1243187643, states[0] = -94.183317, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1254935927, states[0] = -94.183489, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1268275130, states[0] = -94.182913, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1282822748, states[0] = -94.185196, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1295591618, states[0] = -94.051867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308056393, states[0] = -94.183654, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1321002416, states[0] = -94.231263, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1334325508, states[0] = -94.182106, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1347702144, states[0] = -94.185945, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1359246895, states[0] = -94.181920, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1371246405, states[0] = -94.223029, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1381998617, states[0] = -94.196514, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1398705166, states[0] = -94.181620, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1408024423, states[0] = -94.183443, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1422138581, states[0] = -94.193394, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1435168021, states[0] = -6.368602, states[40]= 0.000612
Saving checkpoint... 
Iteration: 1450153408, states[0] = -0.428192, states[40]= 0.000335


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_276.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_276_0_r825248503_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_276_0_r825248503_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 92.331028
     * GNaL_b in INaL: 0.006450
     * Gto_b in Ito: 0.076240
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.029976
     * GKs_b in IKs: 0.002068
     * GK1_b in IK1: 0.157307
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 67.518163
     * GKb_b in IKb: 0.003846
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.041223
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 300.000000
     * CL_0 in membrane: 10000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1450153408
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -0.428192 (After loading)
 - states[40]: 0.000335 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1462827986, states[0] = -94.184479, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1475833607, states[0] = -94.221366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488680368, states[0] = -94.181300, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1498472617, states[0] = -94.181544, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.058694
 - CaMKt in component CaMK (millimolar): 0.000911
 - cass in component intracellular_ions (millimolar): 0.000093
 - nai in component intracellular_ions (millimolar): 7.629351
 - nass in component intracellular_ions (millimolar): 7.629492
 - ki in component intracellular_ions (millimolar): 144.242097
 - kss in component intracellular_ions (millimolar): 144.242087
 - cansr in component intracellular_ions (millimolar): 1.714622
 - cajsr in component intracellular_ions (millimolar): 1.715652
 - cai in component intracellular_ions (millimolar): 0.000098
 - m in component INa (dimensionless): 0.003940
 - hf in component INa (dimensionless): 0.864582
 - hs in component INa (dimensionless): 0.864582
 - j in component INa (dimensionless): 0.864581
 - hsp in component INa (dimensionless): 0.697442
 - jp in component INa (dimensionless): 0.864581
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.706353
 - hLp in component INaL (dimensionless): 0.512423
 - a in component Ito (dimensionless): 0.000660
 - iF in component Ito (dimensionless): 0.999849
 - iS in component Ito (dimensionless): 0.999843
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999849
 - iSp in component Ito (dimensionless): 0.999848
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999971
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003912
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000008
 - xs1 in component IKs (dimensionless): 0.004876
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997550
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
09:44:01 (30825): called boinc_finish(0)

</stderr_txt>
]]>