𝕏

Task 55226724

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_176_1
Workunit 26226948
Created 28 Jun 2024, 6:10:30 UTC
Sent 29 Jun 2024, 6:07:36 UTC
Report deadline 2 Jul 2024, 6:07:36 UTC
Received 30 Jun 2024, 2:09:31 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213646
Run time 2 hours 28 min 54 sec
CPU time 1 hours 56 min 30 sec
Validate state Valid
Credit 45.83
Device peak FLOPS 3.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.79 MB
Peak swap size 32.79 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_176.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_176_1_r160596628_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_10000-conf_176_1_r160596628_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.195207
     * GNaL_b in INaL: 0.004477
     * Gto_b in Ito: 0.094224
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.029828
     * GKs_b in IKs: 0.001887
     * GK1_b in IK1: 0.168074
     * Gncx_b in INaCa_i: 0.000956
     * Pnak_b in INaK: 70.901228
     * GKb_b in IKb: 0.003863
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029499
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 300.000000
     * CL_0 in membrane: 10000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 6703293, states[0] = -94.207484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 19200482, states[0] = -94.154939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30160142, states[0] = -1.027472, states[40]= 0.000433
Saving checkpoint... 
Iteration: 41591501, states[0] = -94.175923, states[40]= 0.000001
Saving checkpoint... 
Iteration: 51410945, states[0] = -94.187241, states[40]= 0.000001
Saving checkpoint... 
Iteration: 60780633, states[0] = -94.182085, states[40]= 0.000001
Saving checkpoint... 
Iteration: 69554814, states[0] = -94.156233, states[40]= 0.000001
Saving checkpoint... 
Iteration: 78767226, states[0] = -94.173786, states[40]= 0.000001
Saving checkpoint... 
Iteration: 91946392, states[0] = -94.192761, states[40]= 0.000001
Saving checkpoint... 
Iteration: 103466220, states[0] = -94.188033, states[40]= 0.000001
Saving checkpoint... 
Iteration: 114573383, states[0] = -94.190778, states[40]= 0.000001
Saving checkpoint... 
Iteration: 125701327, states[0] = -94.215760, states[40]= 0.000001
Saving checkpoint... 
Iteration: 137612903, states[0] = -94.195392, states[40]= 0.000001
Saving checkpoint... 
Iteration: 147430171, states[0] = -94.197219, states[40]= 0.000001
Saving checkpoint... 
Iteration: 159587578, states[0] = -94.195065, states[40]= 0.000001
Saving checkpoint... 
Iteration: 169737462, states[0] = -94.195687, states[40]= 0.000001
Saving checkpoint... 
Iteration: 181282367, states[0] = -94.217071, states[40]= 0.000001
Saving checkpoint... 
Iteration: 193942932, states[0] = -94.195567, states[40]= 0.000001
Saving checkpoint... 
Iteration: 205740841, states[0] = -94.223425, states[40]= 0.000001
Saving checkpoint... 
Iteration: 211716827, states[0] = -94.207468, states[40]= 0.000001
Saving checkpoint... 
Iteration: 225118110, states[0] = 10.403431, states[40]= 0.000032
Saving checkpoint... 
Iteration: 236512044, states[0] = -94.211776, states[40]= 0.000001
Saving checkpoint... 
Iteration: 245622705, states[0] = -94.205139, states[40]= 0.000001
Saving checkpoint... 
Iteration: 256581800, states[0] = -94.210282, states[40]= 0.000001
Saving checkpoint... 
Iteration: 267773337, states[0] = -94.197526, states[40]= 0.000001
Saving checkpoint... 
Iteration: 276833248, states[0] = -94.205716, states[40]= 0.000001
Saving checkpoint... 
Iteration: 285815689, states[0] = -94.227141, states[40]= 0.000001
Saving checkpoint... 
Iteration: 294068877, states[0] = -94.196073, states[40]= 0.000001
Saving checkpoint... 
Iteration: 303965987, states[0] = -94.195990, states[40]= 0.000001
Saving checkpoint... 
Iteration: 315613970, states[0] = -94.202631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326362973, states[0] = -94.215373, states[40]= 0.000001
Saving checkpoint... 
Iteration: 337003424, states[0] = -94.203205, states[40]= 0.000001
Saving checkpoint... 
Iteration: 347051554, states[0] = -94.202593, states[40]= 0.000001
Saving checkpoint... 
Iteration: 356367363, states[0] = -94.215154, states[40]= 0.000001
Saving checkpoint... 
Iteration: 365423163, states[0] = -94.044441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374416918, states[0] = -94.196134, states[40]= 0.000001
Saving checkpoint... 
Iteration: 383932948, states[0] = -94.195708, states[40]= 0.000001
Saving checkpoint... 
Iteration: 393144597, states[0] = -94.196103, states[40]= 0.000001
Saving checkpoint... 
Iteration: 402059407, states[0] = -94.202299, states[40]= 0.000001
Saving checkpoint... 
Iteration: 411525722, states[0] = -94.211064, states[40]= 0.000001
Saving checkpoint... 
Iteration: 421599923, states[0] = -94.209429, states[40]= 0.000001
Saving checkpoint... 
Iteration: 429865567, states[0] = -94.196496, states[40]= 0.000001
Saving checkpoint... 
Iteration: 437320126, states[0] = -94.199638, states[40]= 0.000001
Saving checkpoint... 
Iteration: 449056498, states[0] = -94.195524, states[40]= 0.000001
Saving checkpoint... 
Iteration: 460186791, states[0] = -18.342583, states[40]= 0.001926
Saving checkpoint... 
Iteration: 471533411, states[0] = -94.210658, states[40]= 0.000001
Saving checkpoint... 
Iteration: 483078063, states[0] = -94.195888, states[40]= 0.000001
Saving checkpoint... 
Iteration: 494124673, states[0] = -94.195394, states[40]= 0.000001
Saving checkpoint... 
Iteration: 505963962, states[0] = -94.225855, states[40]= 0.000001
Saving checkpoint... 
Iteration: 517536341, states[0] = -94.197831, states[40]= 0.000001
Saving checkpoint... 
Iteration: 528047419, states[0] = -94.195780, states[40]= 0.000001
Saving checkpoint... 
Iteration: 539248787, states[0] = -94.195320, states[40]= 0.000001
Saving checkpoint... 
Iteration: 550600762, states[0] = -94.197623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562420532, states[0] = -94.198393, states[40]= 0.000001
Saving checkpoint... 
Iteration: 574081612, states[0] = -94.195046, states[40]= 0.000001
Saving checkpoint... 
Iteration: 583519688, states[0] = -94.194922, states[40]= 0.000001
Saving checkpoint... 
Iteration: 593241012, states[0] = -94.195153, states[40]= 0.000001
Saving checkpoint... 
Iteration: 605208105, states[0] = -23.424608, states[40]= 0.006563
Saving checkpoint... 
Iteration: 614044293, states[0] = -94.194863, states[40]= 0.000001
Saving checkpoint... 
Iteration: 626645454, states[0] = -94.207707, states[40]= 0.000001
Saving checkpoint... 
Iteration: 636840426, states[0] = -94.204289, states[40]= 0.000001
Saving checkpoint... 
Iteration: 647295298, states[0] = -94.199011, states[40]= 0.000001
Saving checkpoint... 
Iteration: 657241572, states[0] = -94.199435, states[40]= 0.000001
Saving checkpoint... 
Iteration: 669466935, states[0] = -94.195029, states[40]= 0.000001
Saving checkpoint... 
Iteration: 680153985, states[0] = -2.672841, states[40]= 0.000375
Saving checkpoint... 
Iteration: 690888617, states[0] = -94.226146, states[40]= 0.000001
Saving checkpoint... 
Iteration: 701614140, states[0] = -94.208032, states[40]= 0.000001
Saving checkpoint... 
Iteration: 712189844, states[0] = -94.199699, states[40]= 0.000001
Saving checkpoint... 
Iteration: 722591646, states[0] = -94.196708, states[40]= 0.000001
Saving checkpoint... 
Iteration: 733462802, states[0] = -94.194360, states[40]= 0.000001
Saving checkpoint... 
Iteration: 744043511, states[0] = -94.194346, states[40]= 0.000001
Saving checkpoint... 
Iteration: 754840826, states[0] = -94.195173, states[40]= 0.000001
Saving checkpoint... 
Iteration: 765412425, states[0] = -94.022181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775451703, states[0] = -94.088029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786651287, states[0] = -94.206959, states[40]= 0.000001
Saving checkpoint... 
Iteration: 798042285, states[0] = -94.194721, states[40]= 0.000001
Saving checkpoint... 
Iteration: 807670251, states[0] = -94.195975, states[40]= 0.000001
Saving checkpoint... 
Iteration: 821214766, states[0] = -94.217642, states[40]= 0.000001
Saving checkpoint... 
Iteration: 834424486, states[0] = -94.194326, states[40]= 0.000001
Saving checkpoint... 
Iteration: 846358367, states[0] = -94.213468, states[40]= 0.000001
Saving checkpoint... 
Iteration: 857994620, states[0] = -94.194602, states[40]= 0.000001
Saving checkpoint... 
Iteration: 869111790, states[0] = -94.193896, states[40]= 0.000001
Saving checkpoint... 
Iteration: 880446202, states[0] = -94.079857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895261561, states[0] = -46.332330, states[40]= 0.000951
Saving checkpoint... 
Iteration: 904601747, states[0] = -94.194258, states[40]= 0.000001
Saving checkpoint... 
Iteration: 916766380, states[0] = -94.204366, states[40]= 0.000001
Saving checkpoint... 
Iteration: 927382493, states[0] = -94.197217, states[40]= 0.000001
Saving checkpoint... 
Iteration: 937582846, states[0] = -94.195903, states[40]= 0.000001
Saving checkpoint... 
Iteration: 950051934, states[0] = 31.744900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961797440, states[0] = -94.203676, states[40]= 0.000001
Saving checkpoint... 
Iteration: 973461842, states[0] = -94.193408, states[40]= 0.000001
Saving checkpoint... 
Iteration: 984883872, states[0] = -94.194320, states[40]= 0.000001
Saving checkpoint... 
Iteration: 995342704, states[0] = -93.814670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006817156, states[0] = -94.203183, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1018392083, states[0] = -94.193286, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1030430512, states[0] = -94.054679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043595442, states[0] = -94.193064, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1054220274, states[0] = -94.193249, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1067502808, states[0] = -94.195850, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1080725631, states[0] = -94.219341, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1092678415, states[0] = -94.194805, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1104323678, states[0] = -94.193148, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1116775370, states[0] = -94.203423, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1128028158, states[0] = -94.193445, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1139060943, states[0] = -94.192789, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1150706658, states[0] = -94.217125, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1161994737, states[0] = -94.200066, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1175309073, states[0] = -93.175313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186627945, states[0] = -94.205832, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1197548667, states[0] = -94.195062, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1209814801, states[0] = -94.193329, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1220879950, states[0] = -94.224084, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1234251548, states[0] = -94.192562, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1246836006, states[0] = -94.201938, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1258640119, states[0] = -94.192200, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1270343538, states[0] = -93.816933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280988086, states[0] = -94.222266, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1293535632, states[0] = -94.192095, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1305894943, states[0] = -94.223673, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1318329589, states[0] = -94.192159, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1332775130, states[0] = -94.193435, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1344835088, states[0] = -94.192822, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1357375871, states[0] = -94.195559, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1368643231, states[0] = -94.191762, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1380180118, states[0] = -15.573960, states[40]= 0.000969
Saving checkpoint... 
Iteration: 1392305866, states[0] = -94.195967, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1404726377, states[0] = -94.192434, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1415817373, states[0] = -94.222792, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1424652817, states[0] = -94.192257, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1436841190, states[0] = -94.201105, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1450650514, states[0] = -94.207191, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1464259270, states[0] = -94.191656, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1476548192, states[0] = -94.206349, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1489522898, states[0] = -94.191838, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.068432
 - CaMKt in component CaMK (millimolar): 0.000892
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 7.652570
 - nass in component intracellular_ions (millimolar): 7.652714
 - ki in component intracellular_ions (millimolar): 144.212882
 - kss in component intracellular_ions (millimolar): 144.212871
 - cansr in component intracellular_ions (millimolar): 1.735226
 - cajsr in component intracellular_ions (millimolar): 1.735951
 - cai in component intracellular_ions (millimolar): 0.000099
 - m in component INa (dimensionless): 0.003936
 - hf in component INa (dimensionless): 0.864769
 - hs in component INa (dimensionless): 0.864769
 - j in component INa (dimensionless): 0.864769
 - hsp in component INa (dimensionless): 0.697779
 - jp in component INa (dimensionless): 0.864769
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.706625
 - hLp in component INaL (dimensionless): 0.512753
 - a in component Ito (dimensionless): 0.000659
 - iF in component Ito (dimensionless): 0.999849
 - iS in component Ito (dimensionless): 0.999845
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999849
 - iSp in component Ito (dimensionless): 0.999849
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999986
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004167
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000006
 - xs1 in component IKs (dimensionless): 0.002910
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997548
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
11:34:02 (6221): called boinc_finish(0)

</stderr_txt>
]]>


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