𝕏

Task 55226640

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_3000-conf_376_1
Workunit 26226908
Created 28 Jun 2024, 6:10:25 UTC
Sent 29 Jun 2024, 6:07:36 UTC
Report deadline 2 Jul 2024, 6:07:36 UTC
Received 1 Jul 2024, 23:44:47 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213646
Run time 1 hours 54 min 15 sec
CPU time 1 hours 41 min 47 sec
Validate state Valid
Credit 42.69
Device peak FLOPS 3.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.73 MB
Peak swap size 32.79 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_3000-conf_376.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_3000-conf_376_1_r1945418876_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_3000-conf_376_1_r1945418876_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 91.561615
     * GNaL_b in INaL: 0.005610
     * Gto_b in Ito: 0.074088
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032819
     * GKs_b in IKs: 0.002135
     * GK1_b in IK1: 0.163435
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 69.254525
     * GKb_b in IKb: 0.003891
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036784
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12745979, states[0] = -94.445244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25750688, states[0] = -94.024225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37235835, states[0] = -94.369327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52458495, states[0] = -94.359555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63528698, states[0] = -94.381952, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_3000-conf_376.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_3000-conf_376_1_r1945418876_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_3000-conf_376_1_r1945418876_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 91.561615
     * GNaL_b in INaL: 0.005610
     * Gto_b in Ito: 0.074088
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032819
     * GKs_b in IKs: 0.002135
     * GK1_b in IK1: 0.163435
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 69.254525
     * GKb_b in IKb: 0.003891
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036784
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 63528698
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.381952 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 71089581, states[0] = -94.391217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79645691, states[0] = -46.528462, states[40]= 0.000089
Saving checkpoint... 
Iteration: 92080238, states[0] = -94.396262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102253769, states[0] = -94.024473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113387610, states[0] = -94.395784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124497613, states[0] = -94.373620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135213214, states[0] = -93.791491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146194237, states[0] = -94.405835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157488049, states[0] = -94.375983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168397051, states[0] = -94.341223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179362589, states[0] = -94.400845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190514292, states[0] = 23.742821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201894151, states[0] = -94.399485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212227227, states[0] = -94.406179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223408570, states[0] = -94.378787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234086253, states[0] = 9.888991, states[40]= 0.000025
Saving checkpoint... 
Iteration: 245086017, states[0] = -94.404280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256242640, states[0] = -94.384014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267143708, states[0] = -45.409680, states[40]= 0.000102
Saving checkpoint... 
Iteration: 278279227, states[0] = -94.403788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289775264, states[0] = -94.116125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299979336, states[0] = -94.375772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310168610, states[0] = -94.386094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321431636, states[0] = -94.363971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332387932, states[0] = -94.398255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342792684, states[0] = -94.402310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354214128, states[0] = -93.798069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365311227, states[0] = -94.401201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375781636, states[0] = -94.402235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386439008, states[0] = -94.395023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396953532, states[0] = -94.394178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408055487, states[0] = 23.152066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418819974, states[0] = -94.235081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429619792, states[0] = -94.403327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440287485, states[0] = -94.401008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451416149, states[0] = -94.375290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462751932, states[0] = -94.401946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473897391, states[0] = -94.375515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485184589, states[0] = -94.403116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496086597, states[0] = -94.386618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507680603, states[0] = -94.402800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518663887, states[0] = -94.383059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528474616, states[0] = -94.379799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538064030, states[0] = -94.386943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548442363, states[0] = -94.392344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559129034, states[0] = -94.383841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568868727, states[0] = -94.308401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578364398, states[0] = -94.395528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588966060, states[0] = -94.390601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596578685, states[0] = -94.385390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607756977, states[0] = -94.039096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618885127, states[0] = -94.393936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629985527, states[0] = -94.370481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640364237, states[0] = -94.373960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651221197, states[0] = -93.842104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662510957, states[0] = -94.387380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673060878, states[0] = -94.384977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683377795, states[0] = -94.393276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694488939, states[0] = -94.369383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705455789, states[0] = -94.369855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715893342, states[0] = -94.330841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726463472, states[0] = -94.372654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737528282, states[0] = -94.385428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747949927, states[0] = -94.388884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758669913, states[0] = -94.379077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769182147, states[0] = -94.378430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779766243, states[0] = -94.375112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789923181, states[0] = -94.389487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800586659, states[0] = -94.381868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811737527, states[0] = -93.939312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821880425, states[0] = -94.370614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832236748, states[0] = -94.375366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843298444, states[0] = -94.178271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853536166, states[0] = 26.727823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864612904, states[0] = -94.396300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875875482, states[0] = -94.369930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886549095, states[0] = 24.839508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897582485, states[0] = -94.394021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909205461, states[0] = -93.724711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919582901, states[0] = 11.696950, states[40]= 0.000017
Saving checkpoint... 
Iteration: 930610217, states[0] = -94.395159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941163849, states[0] = -94.396109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952034070, states[0] = -94.381823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958945366, states[0] = -94.361187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969887152, states[0] = -94.388376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980603830, states[0] = -94.378327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991344242, states[0] = -94.369134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001933705, states[0] = -94.366173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012725617, states[0] = -93.865092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020289033, states[0] = -94.149104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030948561, states[0] = -94.361569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041400931, states[0] = -94.332080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052158117, states[0] = -94.394360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062490060, states[0] = -94.376285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073067383, states[0] = -94.389965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083907311, states[0] = -94.385655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094664620, states[0] = -94.374048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105570119, states[0] = 17.810434, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1116646132, states[0] = -94.393253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127406059, states[0] = -94.385039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138670669, states[0] = -81.501431, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1149675764, states[0] = -94.392840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160951759, states[0] = -94.363165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171277904, states[0] = -94.368593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182246106, states[0] = -93.978781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193343537, states[0] = -94.386903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203804777, states[0] = -94.388423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214962885, states[0] = -94.361999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226304902, states[0] = -94.388067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236910366, states[0] = -94.383128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247473593, states[0] = -94.379991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258841339, states[0] = -94.260413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269703327, states[0] = -94.390644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280556146, states[0] = -94.375720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290853350, states[0] = -94.384942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301745268, states[0] = -94.367733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313251288, states[0] = -94.388728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324248243, states[0] = -94.367273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335043706, states[0] = 25.896356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345546916, states[0] = 25.311136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356899564, states[0] = -94.381769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367524473, states[0] = -94.375780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379172779, states[0] = -94.389278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390743522, states[0] = -93.962260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401300878, states[0] = -94.175819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412747747, states[0] = -94.365907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424026062, states[0] = -94.378867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434731079, states[0] = -94.387439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445964465, states[0] = -94.358346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457340168, states[0] = -94.382941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468108840, states[0] = -94.370516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479290459, states[0] = -94.146050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490329206, states[0] = -94.382914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497193682, states[0] = -93.609414, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.232463
 - CaMKt in component CaMK (millimolar): 0.003598
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 7.199537
 - nass in component intracellular_ions (millimolar): 7.199673
 - ki in component intracellular_ions (millimolar): 144.445621
 - kss in component intracellular_ions (millimolar): 144.445604
 - cansr in component intracellular_ions (millimolar): 2.426830
 - cajsr in component intracellular_ions (millimolar): 2.427314
 - cai in component intracellular_ions (millimolar): 0.000104
 - m in component INa (dimensionless): 0.003871
 - hf in component INa (dimensionless): 0.867891
 - hs in component INa (dimensionless): 0.867892
 - j in component INa (dimensionless): 0.867898
 - hsp in component INa (dimensionless): 0.703441
 - jp in component INa (dimensionless): 0.867902
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.711234
 - hLp in component INaL (dimensionless): 0.515681
 - a in component Ito (dimensionless): 0.000652
 - iF in component Ito (dimensionless): 0.999853
 - iS in component Ito (dimensionless): 0.999853
 - ap in component Ito (dimensionless): 0.000332
 - iFp in component Ito (dimensionless): 0.999853
 - iSp in component Ito (dimensionless): 0.999853
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.991188
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005044
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.024732
 - xs1 in component IKs (dimensionless): 0.067855
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997507
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:03:44 (30889): called boinc_finish(0)

</stderr_txt>
]]>


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