𝕏

Task 55226609

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_10000-conf_376_0
Workunit 26226893
Created 28 Jun 2024, 6:10:25 UTC
Sent 29 Jun 2024, 6:07:36 UTC
Report deadline 2 Jul 2024, 6:07:36 UTC
Received 30 Jun 2024, 2:09:31 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213646
Run time 2 hours 27 min 14 sec
CPU time 1 hours 57 min 31 sec
Validate state Valid
Credit 44.48
Device peak FLOPS 3.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.79 MB
Peak swap size 32.79 GB
Peak disk usage 0.04 MB

Stderr output

<core_client_version>8.0.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_10000-conf_376.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_10000-conf_376_0_r315466481_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_10000-conf_376_0_r315466481_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 91.561615
     * GNaL_b in INaL: 0.005610
     * Gto_b in Ito: 0.074088
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032819
     * GKs_b in IKs: 0.002135
     * GK1_b in IK1: 0.163435
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 69.254525
     * GKb_b in IKb: 0.003891
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036784
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 300.000000
     * CL_0 in membrane: 10000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8457996, states[0] = -94.390114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 19689319, states[0] = -94.301654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31434078, states[0] = -94.273686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42098175, states[0] = -94.245665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52497628, states[0] = -94.234351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61741412, states[0] = -94.239801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70333553, states[0] = -94.110011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81040934, states[0] = -94.258139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92955088, states[0] = -94.230531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104824818, states[0] = -94.228111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116293598, states[0] = -94.253710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128931197, states[0] = -94.231406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139148527, states[0] = -94.231738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149307229, states[0] = -94.232051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160048993, states[0] = 26.092807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171449060, states[0] = -94.252676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183038291, states[0] = -94.235972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194946391, states[0] = -94.232607, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_10000-conf_376.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_10000-conf_376_0_r315466481_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_10000-conf_376_0_r315466481_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 91.561615
     * GNaL_b in INaL: 0.005610
     * Gto_b in Ito: 0.074088
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032819
     * GKs_b in IKs: 0.002135
     * GK1_b in IK1: 0.163435
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 69.254525
     * GKb_b in IKb: 0.003891
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036784
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 300.000000
     * CL_0 in membrane: 10000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 194946391
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.232607 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 203079982, states[0] = -94.236066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212941204, states[0] = -94.236710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223635552, states[0] = -94.234550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234018436, states[0] = -94.233859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244746993, states[0] = -94.233012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253489902, states[0] = -94.234933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262767722, states[0] = -94.237622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271463295, states[0] = -94.252973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280365144, states[0] = -94.167537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288730632, states[0] = -94.234316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296831867, states[0] = -94.246075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305774390, states[0] = -94.275463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315020998, states[0] = 26.231629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323591329, states[0] = -94.234503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332777068, states[0] = -94.237366, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_10000-conf_376.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_10000-conf_376_0_r315466481_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_10000-conf_376_0_r315466481_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 91.561615
     * GNaL_b in INaL: 0.005610
     * Gto_b in Ito: 0.074088
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032819
     * GKs_b in IKs: 0.002135
     * GK1_b in IK1: 0.163435
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 69.254525
     * GKb_b in IKb: 0.003891
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036784
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 300.000000
     * CL_0 in membrane: 10000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 332777068
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.237366 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 341966132, states[0] = -94.244082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353386810, states[0] = -94.234913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365931855, states[0] = -94.269605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376072070, states[0] = -94.264178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384943980, states[0] = -94.232424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393301689, states[0] = -94.235000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405345337, states[0] = -94.138213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416502682, states[0] = -94.251555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427178032, states[0] = -94.241355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439099463, states[0] = -94.233090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450579379, states[0] = -94.271530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461308110, states[0] = -94.256197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472186430, states[0] = -94.241081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482269979, states[0] = -94.240253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491920842, states[0] = -94.244043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501831160, states[0] = -94.245257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512676670, states[0] = -94.237169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522988004, states[0] = -94.235582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534144691, states[0] = -94.232621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544590854, states[0] = -94.232051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554886706, states[0] = -94.231747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566508402, states[0] = -94.250792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576095676, states[0] = -94.262477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590109709, states[0] = -2.188231, states[40]= 0.000145
Saving checkpoint... 
Iteration: 602416036, states[0] = -94.238528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613608724, states[0] = -94.233248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624562737, states[0] = -94.231738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634042766, states[0] = -94.232344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649197677, states[0] = -94.232056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661877740, states[0] = -94.243905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671790954, states[0] = -94.245139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684697205, states[0] = -94.231353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694443879, states[0] = -94.231564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705103966, states[0] = 1.958102, states[40]= 0.000094
Saving checkpoint... 
Iteration: 716913547, states[0] = -94.243180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729534822, states[0] = -94.231318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741666153, states[0] = -94.246922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753006939, states[0] = -94.234521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764896404, states[0] = -94.230842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777228884, states[0] = -94.239371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788070413, states[0] = -94.234117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800034894, states[0] = 27.658628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811412701, states[0] = -94.251962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821608546, states[0] = -94.247652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833388625, states[0] = -94.232869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845631423, states[0] = -94.273419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856605230, states[0] = -94.247567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868056993, states[0] = -94.233828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880044760, states[0] = 26.823075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891315803, states[0] = -94.254150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902780661, states[0] = -94.234932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913622403, states[0] = -94.231935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924195324, states[0] = -94.230885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936714036, states[0] = -94.245254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948186936, states[0] = -94.233008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960024073, states[0] = 26.847692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971450397, states[0] = -94.250375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983142777, states[0] = -94.233014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995356490, states[0] = -94.152735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007890048, states[0] = -94.233944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019642104, states[0] = -94.229973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031409082, states[0] = -94.251113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042195892, states[0] = -94.238556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055116765, states[0] = -8.369644, states[40]= 0.000185
Saving checkpoint... 
Iteration: 1067789110, states[0] = -94.234183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081718001, states[0] = -94.244569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093632766, states[0] = -94.231143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105455686, states[0] = -94.237939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117565339, states[0] = -94.235272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128961927, states[0] = -94.230358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141102867, states[0] = -94.259813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153195279, states[0] = -94.232104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165504787, states[0] = -94.255439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176853123, states[0] = -94.242057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186663034, states[0] = -94.245079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198485048, states[0] = -94.231049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212022977, states[0] = -94.239689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226081822, states[0] = -94.260207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238691585, states[0] = -94.230396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251658428, states[0] = -94.244885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262457100, states[0] = -94.235403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270571903, states[0] = -94.267238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284614569, states[0] = -94.228867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295954550, states[0] = -94.264759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308324293, states[0] = -94.231027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319679964, states[0] = -94.228656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331016602, states[0] = -94.262195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346372016, states[0] = -94.250705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358044016, states[0] = -94.231786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371306211, states[0] = -94.252371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387372871, states[0] = -94.235516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402087521, states[0] = -94.238142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416359528, states[0] = -94.250732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430869780, states[0] = -94.267493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442108248, states[0] = -94.237746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453886477, states[0] = -94.229099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468458501, states[0] = -94.229965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479763327, states[0] = -94.227898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493045366, states[0] = -94.231205, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.103610
 - CaMKt in component CaMK (millimolar): 0.000967
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 6.945370
 - nass in component intracellular_ions (millimolar): 6.945499
 - ki in component intracellular_ions (millimolar): 144.806599
 - kss in component intracellular_ions (millimolar): 144.806588
 - cansr in component intracellular_ions (millimolar): 2.331347
 - cajsr in component intracellular_ions (millimolar): 2.331430
 - cai in component intracellular_ions (millimolar): 0.000104
 - m in component INa (dimensionless): 0.003922
 - hf in component INa (dimensionless): 0.865444
 - hs in component INa (dimensionless): 0.865444
 - j in component INa (dimensionless): 0.865444
 - hsp in component INa (dimensionless): 0.698997
 - jp in component INa (dimensionless): 0.865444
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707604
 - hLp in component INaL (dimensionless): 0.513949
 - a in component Ito (dimensionless): 0.000658
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.999850
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.999850
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999992
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005024
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000005
 - xs1 in component IKs (dimensionless): 0.002037
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997539
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:01:59 (8701): called boinc_finish(0)

</stderr_txt>
]]>


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