𝕏

Task 55226596

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_1000-conf_676_1
Workunit 26226886
Created 28 Jun 2024, 6:10:25 UTC
Sent 29 Jun 2024, 6:07:36 UTC
Report deadline 2 Jul 2024, 6:07:36 UTC
Received 30 Jun 2024, 2:09:31 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213646
Run time 2 hours 26 min 49 sec
CPU time 1 hours 57 min 43 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 3.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.78 MB
Peak swap size 32.79 GB
Peak disk usage 0.04 MB

Stderr output

<core_client_version>8.0.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_1000-conf_676.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_1000-conf_676_1_r2107252282_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_1000-conf_676_1_r2107252282_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 98.770860
     * GNaL_b in INaL: 0.004998
     * Gto_b in Ito: 0.088544
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033480
     * GKs_b in IKs: 0.002139
     * GK1_b in IK1: 0.173751
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 73.548253
     * GKb_b in IKb: 0.003822
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.042593
     * celltype in environment: 1.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8278686, states[0] = -94.639169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20406222, states[0] = -94.730917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30717453, states[0] = -94.359807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41552036, states[0] = 20.088700, states[40]= 0.000002
Saving checkpoint... 
Iteration: 53218826, states[0] = -94.388709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62914685, states[0] = -94.771019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72815221, states[0] = -94.701164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84533672, states[0] = 22.742362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95388622, states[0] = -94.778869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107137170, states[0] = -61.570112, states[40]= 0.000102
Saving checkpoint... 
Iteration: 118968884, states[0] = -94.807138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131121283, states[0] = -40.576850, states[40]= 0.000990
Saving checkpoint... 
Iteration: 141632445, states[0] = -55.556294, states[40]= 0.000223
Saving checkpoint... 
Iteration: 153205230, states[0] = -94.339335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164624709, states[0] = -45.285193, states[40]= 0.000679
Saving checkpoint... 
Iteration: 175975601, states[0] = -94.807829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187566785, states[0] = 13.228118, states[40]= 0.000061
Saving checkpoint... 
Iteration: 199358068, states[0] = -94.762143, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_1000-conf_676.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_1000-conf_676_1_r2107252282_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_1000-conf_676_1_r2107252282_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 98.770860
     * GNaL_b in INaL: 0.004998
     * Gto_b in Ito: 0.088544
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033480
     * GKs_b in IKs: 0.002139
     * GK1_b in IK1: 0.173751
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 73.548253
     * GKb_b in IKb: 0.003822
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.042593
     * celltype in environment: 1.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 199358068
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.762143 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 208493681, states[0] = -94.807302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217617024, states[0] = -35.271316, states[40]= 0.001377
Saving checkpoint... 
Iteration: 229560970, states[0] = 15.828702, states[40]= 0.000023
Saving checkpoint... 
Iteration: 240782816, states[0] = -94.653682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251398966, states[0] = -94.782860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260738355, states[0] = -94.512342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269508034, states[0] = 18.490010, states[40]= 0.000004
Saving checkpoint... 
Iteration: 278521572, states[0] = 22.305842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286673567, states[0] = -94.056970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295868415, states[0] = -94.762135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304994082, states[0] = -94.799572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314610770, states[0] = -27.332410, states[40]= 0.001469
Saving checkpoint... 
Iteration: 323824994, states[0] = -94.718750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332169800, states[0] = -94.004809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341397639, states[0] = -94.774799, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_1000-conf_676.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_1000-conf_676_1_r2107252282_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_EPI_1000-conf_676_1_r2107252282_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 98.770860
     * GNaL_b in INaL: 0.004998
     * Gto_b in Ito: 0.088544
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033480
     * GKs_b in IKs: 0.002139
     * GK1_b in IK1: 0.173751
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 73.548253
     * GKb_b in IKb: 0.003822
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.042593
     * celltype in environment: 1.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 341397639
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.774799 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 351295536, states[0] = -94.670773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362327746, states[0] = -94.718935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374179469, states[0] = -94.110719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384755032, states[0] = -94.564893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392724771, states[0] = -94.437404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401811305, states[0] = -94.693315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413954352, states[0] = -94.785783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424294995, states[0] = -94.663651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435203920, states[0] = -94.307991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446616606, states[0] = -34.726588, states[40]= 0.001406
Saving checkpoint... 
Iteration: 456950158, states[0] = -94.781447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467908670, states[0] = -94.768917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478677723, states[0] = -94.084414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488909214, states[0] = -94.767380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498912913, states[0] = -94.767929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510341329, states[0] = -94.721625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520618015, states[0] = -36.531893, states[40]= 0.001297
Saving checkpoint... 
Iteration: 532067423, states[0] = 12.923488, states[40]= 0.000067
Saving checkpoint... 
Iteration: 543445291, states[0] = -94.773318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554911066, states[0] = -94.762612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565634184, states[0] = -58.024803, states[40]= 0.000166
Saving checkpoint... 
Iteration: 577032245, states[0] = 22.672196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587236603, states[0] = -94.477253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599402665, states[0] = -94.755620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612818209, states[0] = -94.685752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625130941, states[0] = -53.666465, states[40]= 0.000281
Saving checkpoint... 
Iteration: 636256256, states[0] = -94.547858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645300795, states[0] = -94.655860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660263847, states[0] = -94.569529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673470404, states[0] = -94.766789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684029204, states[0] = 22.749729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696288940, states[0] = -94.628995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705666057, states[0] = -93.895763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716309138, states[0] = -94.663844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729080436, states[0] = 5.550481, states[40]= 0.000419
Saving checkpoint... 
Iteration: 740896118, states[0] = -94.741046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753283657, states[0] = -94.612840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765147478, states[0] = -79.009057, states[40]= 0.000010
Saving checkpoint... 
Iteration: 776236039, states[0] = -94.458926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787231602, states[0] = -94.437808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799924929, states[0] = -94.746992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810841893, states[0] = -94.697281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822288001, states[0] = -94.616498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834000398, states[0] = -45.362111, states[40]= 0.000010
Saving checkpoint... 
Iteration: 845896025, states[0] = -94.732312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859157164, states[0] = -92.565161, states[40]= 0.000001
Saving checkpoint... 
Iteration: 870609896, states[0] = -26.182892, states[40]= 0.001403
Saving checkpoint... 
Iteration: 881874742, states[0] = -94.717734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892552547, states[0] = 18.918856, states[40]= 0.000005
Saving checkpoint... 
Iteration: 903931094, states[0] = -94.740130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915152365, states[0] = -88.056482, states[40]= 0.000003
Saving checkpoint... 
Iteration: 927120110, states[0] = -39.214183, states[40]= 0.001099
Saving checkpoint... 
Iteration: 938859265, states[0] = -94.702084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950989971, states[0] = -94.745868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962880172, states[0] = -94.714329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973680093, states[0] = -94.065248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984914698, states[0] = -94.728427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996837633, states[0] = -94.677531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009234628, states[0] = -94.433089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020407194, states[0] = -94.722708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030679166, states[0] = -94.051386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042024394, states[0] = 22.589136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052225231, states[0] = -94.384151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065082431, states[0] = 4.182932, states[40]= 0.000526
Saving checkpoint... 
Iteration: 1076826260, states[0] = -94.657808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089684715, states[0] = -94.098681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102316024, states[0] = -94.642055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114442814, states[0] = -94.725605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127083708, states[0] = 3.252730, states[40]= 0.000610
Saving checkpoint... 
Iteration: 1138384238, states[0] = -94.702124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151215239, states[0] = -94.320344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163161045, states[0] = -93.531116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174261178, states[0] = -94.518524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185809474, states[0] = -94.625310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194878794, states[0] = -94.694336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206909824, states[0] = -94.708247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219226104, states[0] = -94.374502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232708863, states[0] = -94.273659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245613604, states[0] = -30.832877, states[40]= 0.001506
Saving checkpoint... 
Iteration: 1258608281, states[0] = -24.110504, states[40]= 0.001284
Saving checkpoint... 
Iteration: 1269073310, states[0] = 9.911020, states[40]= 0.000160
Saving checkpoint... 
Iteration: 1279934532, states[0] = -94.710000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292718204, states[0] = -94.325713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303705772, states[0] = -94.247091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316879047, states[0] = -94.684415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329026939, states[0] = 22.728893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339982485, states[0] = -94.713114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352549506, states[0] = 19.833080, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1366349810, states[0] = -94.658757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377586534, states[0] = 1.048145, states[40]= 0.000812
Saving checkpoint... 
Iteration: 1394007125, states[0] = 17.800515, states[40]= -0.000002
Saving checkpoint... 
Iteration: 1408670038, states[0] = -93.914586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423099082, states[0] = -12.313164, states[40]= 0.001221
Saving checkpoint... 
Iteration: 1438129335, states[0] = -51.434790, states[40]= 0.000356
Saving checkpoint... 
Iteration: 1448392176, states[0] = -94.680637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459518251, states[0] = 21.841982, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1472710056, states[0] = -94.261065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484402618, states[0] = -94.682419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496376055, states[0] = -94.667713, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.577103
 - CaMKt in component CaMK (millimolar): 0.027229
 - cass in component intracellular_ions (millimolar): 0.000107
 - nai in component intracellular_ions (millimolar): 7.798862
 - nass in component intracellular_ions (millimolar): 7.799036
 - ki in component intracellular_ions (millimolar): 143.153904
 - kss in component intracellular_ions (millimolar): 143.153864
 - cansr in component intracellular_ions (millimolar): 3.228210
 - cajsr in component intracellular_ions (millimolar): 3.207275
 - cai in component intracellular_ions (millimolar): 0.000111
 - m in component INa (dimensionless): 0.003739
 - hf in component INa (dimensionless): 0.874251
 - hs in component INa (dimensionless): 0.874248
 - j in component INa (dimensionless): 0.874226
 - hsp in component INa (dimensionless): 0.715096
 - jp in component INa (dimensionless): 0.874207
 - mL in component INaL (dimensionless): 0.000053
 - hL in component INaL (dimensionless): 0.702338
 - hLp in component INaL (dimensionless): 0.445641
 - a in component Ito (dimensionless): 0.000637
 - iF in component Ito (dimensionless): 0.999862
 - iS in component Ito (dimensionless): 0.999862
 - ap in component Ito (dimensionless): 0.000325
 - iFp in component Ito (dimensionless): 0.999862
 - iSp in component Ito (dimensionless): 0.999862
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.920824
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999879
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.006601
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.313200
 - xs1 in component IKs (dimensionless): 0.266104
 - xs2 in component IKs (dimensionless): 0.000091
 - xk1 in component IK1 (dimensionless): 0.997421
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:01:10 (8702): called boinc_finish(0)

</stderr_txt>
]]>


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