𝕏

Task 55226494

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_5000-conf_176_1
Workunit 26226835
Created 28 Jun 2024, 6:10:25 UTC
Sent 29 Jun 2024, 6:07:36 UTC
Report deadline 2 Jul 2024, 6:07:36 UTC
Received 1 Jul 2024, 23:44:47 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213646
Run time 2 hours 9 min 41 sec
CPU time 1 hours 50 min 35 sec
Validate state Valid
Credit 45.40
Device peak FLOPS 3.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.59 MB
Peak swap size 32.90 GB
Peak disk usage 1.56 MB

Stderr output

<core_client_version>8.0.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_5000-conf_176.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_5000-conf_176_1_r1007996986_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_5000-conf_176_1_r1007996986_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.195207
     * GNaL_b in INaL: 0.004477
     * Gto_b in Ito: 0.094224
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.029828
     * GKs_b in IKs: 0.001887
     * GK1_b in IK1: 0.168074
     * Gncx_b in INaCa_i: 0.000956
     * Pnak_b in INaK: 70.901228
     * GKb_b in IKb: 0.003863
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029499
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1497500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 14869549, states[0] = -94.626581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29077507, states[0] = -94.560950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41592642, states[0] = -94.529326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54931580, states[0] = -94.503698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69036205, states[0] = -94.499618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81150506, states[0] = -94.499773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95187475, states[0] = -68.679813, states[40]= 0.000005
Saving checkpoint... 
Iteration: 108758620, states[0] = -94.489452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120905241, states[0] = -94.493881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133353714, states[0] = -94.492805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147566252, states[0] = 15.583734, states[40]= 0.003223
Saving checkpoint... 
Iteration: 160713184, states[0] = -94.489031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173362625, states[0] = -94.490074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187717503, states[0] = -93.908416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202241043, states[0] = -94.471083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215106409, states[0] = -2.799477, states[40]= 0.003934
Saving checkpoint... 
Iteration: 226538790, states[0] = -94.477382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240692020, states[0] = -94.486218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252838466, states[0] = -94.334597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265371181, states[0] = -94.375557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278167795, states[0] = -94.484619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291217525, states[0] = -94.482330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305418531, states[0] = -94.416363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319810551, states[0] = -94.469840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332187900, states[0] = -94.470578, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_5000-conf_176.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_5000-conf_176_1_r1007996986_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_5000-conf_176_1_r1007996986_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.195207
     * GNaL_b in INaL: 0.004477
     * Gto_b in Ito: 0.094224
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.029828
     * GKs_b in IKs: 0.001887
     * GK1_b in IK1: 0.168074
     * Gncx_b in INaCa_i: 0.000956
     * Pnak_b in INaK: 70.901228
     * GKb_b in IKb: 0.003863
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029499
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1497500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 332187900
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.470578 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 343602469, states[0] = -94.484497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357165329, states[0] = -94.470694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369446688, states[0] = -94.472353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380482846, states[0] = -94.449914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394258466, states[0] = -94.474140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405953545, states[0] = -94.487221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418404011, states[0] = -94.487917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431271072, states[0] = -94.481124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445969733, states[0] = -94.486917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459381184, states[0] = -94.472856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472852109, states[0] = -94.352875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486950510, states[0] = -94.472213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499880619, states[0] = -94.469259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511150616, states[0] = -94.483376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525082930, states[0] = 9.254058, states[40]= 0.004157
Saving checkpoint... 
Iteration: 537757029, states[0] = -94.152838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552311125, states[0] = -94.469605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564731062, states[0] = -94.470079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578609528, states[0] = -94.484141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591939865, states[0] = -94.472219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605976488, states[0] = -94.486670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618895869, states[0] = -94.478796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631087300, states[0] = -94.484543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644014443, states[0] = -94.476962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655863520, states[0] = -94.488116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667894897, states[0] = -94.397805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680915205, states[0] = -94.487558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694495110, states[0] = -94.471670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706986109, states[0] = -94.471734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721501827, states[0] = -94.477081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734321646, states[0] = -94.473204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748069119, states[0] = -94.472845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762194737, states[0] = -94.470152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775477982, states[0] = -94.447661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789850818, states[0] = -94.469187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803740784, states[0] = -94.481385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816729039, states[0] = -94.474111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829321072, states[0] = -94.473133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843233910, states[0] = -94.487026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857567903, states[0] = 15.066631, states[40]= 0.003335
Saving checkpoint... 
Iteration: 870155338, states[0] = -39.891902, states[40]= 0.000491
Saving checkpoint... 
Iteration: 882419397, states[0] = -94.468744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893854886, states[0] = -94.479257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909366491, states[0] = -94.472627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921394680, states[0] = -94.478570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934833538, states[0] = -94.469166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950960423, states[0] = -94.486662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964435937, states[0] = -94.471951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977000116, states[0] = -94.471400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992278168, states[0] = -94.469442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005458371, states[0] = -94.438811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019413779, states[0] = -94.472102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030323999, states[0] = -94.311035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044222918, states[0] = -94.473995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057067893, states[0] = -94.470805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069345685, states[0] = -94.472696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083874376, states[0] = -94.478774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095867725, states[0] = -94.487729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109702059, states[0] = -94.469823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124030341, states[0] = -94.476347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137199897, states[0] = -94.469814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150769425, states[0] = -94.487511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164927515, states[0] = -94.468472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176759246, states[0] = -94.473490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190880934, states[0] = -94.487538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203809913, states[0] = -94.479790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216781271, states[0] = -94.473224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230618861, states[0] = -94.479494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244180322, states[0] = -94.474321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256975340, states[0] = -94.471377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271396039, states[0] = -94.478264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285224417, states[0] = -94.024801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298301130, states[0] = -94.487693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311389745, states[0] = -94.478335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324407152, states[0] = -94.471914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337981177, states[0] = -94.448477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351832250, states[0] = -94.472598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362955109, states[0] = -94.436927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374558444, states[0] = -94.470619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388324362, states[0] = -94.487674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402623259, states[0] = -15.245216, states[40]= 0.001660
Saving checkpoint... 
Iteration: 1415348492, states[0] = -94.347388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430517387, states[0] = -94.460554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442829480, states[0] = -94.319677, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_5000-conf_176.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_5000-conf_176_1_r1007996986_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_5000-conf_176_1_r1007996986_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.195207
     * GNaL_b in INaL: 0.004477
     * Gto_b in Ito: 0.094224
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.029828
     * GKs_b in IKs: 0.001887
     * GK1_b in IK1: 0.168074
     * Gncx_b in INaCa_i: 0.000956
     * Pnak_b in INaK: 70.901228
     * GKb_b in IKb: 0.003863
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029499
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1497500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1442829480
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.319677 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1455856922, states[0] = -94.487512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468461800, states[0] = -94.486220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481318552, states[0] = -94.479412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490509960, states[0] = -94.458323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498703496, states[0] = -94.481536, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.343817
 - CaMKt in component CaMK (millimolar): 0.001177
 - cass in component intracellular_ions (millimolar): 0.000089
 - nai in component intracellular_ions (millimolar): 6.322709
 - nass in component intracellular_ions (millimolar): 6.322798
 - ki in component intracellular_ions (millimolar): 145.594953
 - kss in component intracellular_ions (millimolar): 145.594943
 - cansr in component intracellular_ions (millimolar): 1.599397
 - cajsr in component intracellular_ions (millimolar): 1.599437
 - cai in component intracellular_ions (millimolar): 0.000092
 - m in component INa (dimensionless): 0.003828
 - hf in component INa (dimensionless): 0.869974
 - hs in component INa (dimensionless): 0.869974
 - j in component INa (dimensionless): 0.869975
 - hsp in component INa (dimensionless): 0.707237
 - jp in component INa (dimensionless): 0.869976
 - mL in component INaL (dimensionless): 0.000055
 - hL in component INaL (dimensionless): 0.714209
 - hLp in component INaL (dimensionless): 0.521893
 - a in component Ito (dimensionless): 0.000647
 - iF in component Ito (dimensionless): 0.999856
 - iS in component Ito (dimensionless): 0.997741
 - ap in component Ito (dimensionless): 0.000330
 - iFp in component Ito (dimensionless): 0.999856
 - iSp in component Ito (dimensionless): 0.999252
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998878
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003242
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001769
 - xs1 in component IKs (dimensionless): 0.022807
 - xs2 in component IKs (dimensionless): 0.000093
 - xk1 in component IK1 (dimensionless): 0.997480
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:44:59 (30824): called boinc_finish(0)

</stderr_txt>
]]>


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