𝕏

Task 55226488

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_2000-conf_776_1
Workunit 26226832
Created 28 Jun 2024, 6:10:25 UTC
Sent 29 Jun 2024, 6:07:36 UTC
Report deadline 2 Jul 2024, 6:07:36 UTC
Received 1 Jul 2024, 23:44:47 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213646
Run time 1 hours 59 min 35 sec
CPU time 1 hours 44 min 15 sec
Validate state Valid
Credit 43.53
Device peak FLOPS 3.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.13 MB
Peak swap size 32.91 GB
Peak disk usage 0.64 MB

Stderr output

<core_client_version>8.0.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_2000-conf_776.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_2000-conf_776_1_r350085733_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_2000-conf_776_1_r350085733_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.938809
     * GNaL_b in INaL: 0.005199
     * Gto_b in Ito: 0.079092
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.031778
     * GKs_b in IKs: 0.002097
     * GK1_b in IK1: 0.162305
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 73.196270
     * GKb_b in IKb: 0.003692
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.020784
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 13840563, states[0] = -94.760586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24653006, states[0] = -94.703240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39605562, states[0] = -94.663983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51796971, states[0] = -94.655381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65546017, states[0] = -94.630949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79365050, states[0] = -94.536464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91924856, states[0] = -94.632754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105811953, states[0] = -94.632045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119171326, states[0] = -68.946940, states[40]= 0.000004
Saving checkpoint... 
Iteration: 134079267, states[0] = 7.922421, states[40]= 0.004534
Saving checkpoint... 
Iteration: 148795517, states[0] = -94.627804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160231679, states[0] = -94.242910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174929373, states[0] = -94.624244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188425770, states[0] = -94.570779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201280578, states[0] = -94.389580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215888291, states[0] = -94.624518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227996563, states[0] = -94.621556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241764993, states[0] = -94.625954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257157253, states[0] = -54.259553, states[40]= 0.000049
Saving checkpoint... 
Iteration: 269954599, states[0] = -94.622497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284271234, states[0] = -94.365880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298523179, states[0] = -94.606571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311256954, states[0] = -94.326026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325155283, states[0] = -52.400602, states[40]= 0.000067
Saving checkpoint... 
Iteration: 338319833, states[0] = -94.465193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350415422, states[0] = -94.563594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363407523, states[0] = -94.558399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377064432, states[0] = 14.361792, states[40]= 0.003768
Saving checkpoint... 
Iteration: 389447252, states[0] = -94.580875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401906742, states[0] = -94.623416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416418796, states[0] = -94.565557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429917528, states[0] = -94.623096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442087196, states[0] = 3.952395, states[40]= 0.004673
Saving checkpoint... 
Iteration: 455381442, states[0] = -94.538150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469128322, states[0] = -28.333047, states[40]= 0.001260
Saving checkpoint... 
Iteration: 482086113, states[0] = 4.535740, states[40]= 0.004672
Saving checkpoint... 
Iteration: 493205685, states[0] = -94.114601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505452652, states[0] = -94.583124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516097272, states[0] = -2.159405, states[40]= 0.004205
Saving checkpoint... 
Iteration: 531573604, states[0] = -94.615246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541812090, states[0] = -94.624941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556975454, states[0] = -94.621307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569253172, states[0] = -94.314013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584473227, states[0] = -94.591322, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_2000-conf_776.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_2000-conf_776_1_r350085733_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_2000-conf_776_1_r350085733_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.938809
     * GNaL_b in INaL: 0.005199
     * Gto_b in Ito: 0.079092
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.031778
     * GKs_b in IKs: 0.002097
     * GK1_b in IK1: 0.162305
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 73.196270
     * GKb_b in IKb: 0.003692
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.020784
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 584473227
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.591322 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 597354671, states[0] = -94.511373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609205774, states[0] = -94.115334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622211719, states[0] = -94.158210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631599900, states[0] = -94.618260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639495419, states[0] = -94.598597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643588665, states[0] = -94.616979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656075027, states[0] = 9.944330, states[40]= 0.004371
Saving checkpoint... 
Iteration: 667181037, states[0] = -81.857971, states[40]= 0.000001
Saving checkpoint... 
Iteration: 678634280, states[0] = -94.621167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689088989, states[0] = 2.960536, states[40]= 0.004657
Saving checkpoint... 
Iteration: 700258240, states[0] = -94.329079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711693026, states[0] = -94.623953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722431635, states[0] = -94.572373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733450739, states[0] = -94.581837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744763151, states[0] = -94.624853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755676335, states[0] = -94.623297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767024123, states[0] = 26.452535, states[40]= 0.001924
Saving checkpoint... 
Iteration: 777851910, states[0] = -94.623895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788867222, states[0] = -94.623578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798690730, states[0] = -94.623721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809705266, states[0] = -94.624093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820568669, states[0] = -94.614001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831297137, states[0] = -94.423845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841599905, states[0] = -94.617868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852124452, states[0] = -25.015129, states[40]= 0.001366
Saving checkpoint... 
Iteration: 862891465, states[0] = -94.622914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873286178, states[0] = -94.400664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884558936, states[0] = -94.612382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895663109, states[0] = -94.622459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906120469, states[0] = -21.576102, states[40]= 0.001352
Saving checkpoint... 
Iteration: 916677277, states[0] = -94.623033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927810645, states[0] = -94.624237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938095044, states[0] = -0.680758, states[40]= 0.004402
Saving checkpoint... 
Iteration: 948335411, states[0] = -94.486899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958950145, states[0] = -94.621255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969637394, states[0] = -94.620839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980000373, states[0] = -48.359727, states[40]= 0.000002
Saving checkpoint... 
Iteration: 991257171, states[0] = -94.325359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002350486, states[0] = -94.505813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013523575, states[0] = -94.605291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024712939, states[0] = -94.623856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035623863, states[0] = -94.619717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046435062, states[0] = -94.573595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058173188, states[0] = -70.771471, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1069516974, states[0] = -94.603626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080237897, states[0] = -94.262303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090672034, states[0] = -94.622497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101659663, states[0] = -94.621905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112164291, states[0] = -61.034891, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1123176129, states[0] = -74.606522, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1133961914, states[0] = -94.620607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141466964, states[0] = -94.587907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148815448, states[0] = -94.623767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160465145, states[0] = -94.587156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168046336, states[0] = 20.691259, states[40]= 0.002525
Saving checkpoint... 
Iteration: 1178727963, states[0] = -94.623813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189370742, states[0] = -94.526988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200548574, states[0] = -94.610025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211669125, states[0] = -94.622146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222185938, states[0] = -88.682913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232578320, states[0] = -94.614579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243763430, states[0] = -94.623921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254332500, states[0] = -94.482315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265418373, states[0] = -94.563708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275916864, states[0] = -94.621532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286821257, states[0] = -94.623435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297685439, states[0] = -94.622618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308277338, states[0] = -94.379237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319431592, states[0] = -94.571233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330538529, states[0] = -94.607887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340898479, states[0] = -94.621858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352273179, states[0] = -94.368801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362591092, states[0] = -94.615922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373807630, states[0] = -94.623437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384184904, states[0] = -87.437883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395509958, states[0] = -94.601248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406106110, states[0] = -8.921622, states[40]= 0.002818
Saving checkpoint... 
Iteration: 1417218991, states[0] = -94.189533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427932586, states[0] = -94.620846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438640215, states[0] = -94.620152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449871486, states[0] = -94.622256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461044127, states[0] = 21.382717, states[40]= 0.002390
Saving checkpoint... 
Iteration: 1471381039, states[0] = -94.535895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482649041, states[0] = -94.620616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491190449, states[0] = -92.253269, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.494786
 - CaMKt in component CaMK (millimolar): 0.004246
 - cass in component intracellular_ions (millimolar): 0.000086
 - nai in component intracellular_ions (millimolar): 6.419653
 - nass in component intracellular_ions (millimolar): 6.419741
 - ki in component intracellular_ions (millimolar): 145.489054
 - kss in component intracellular_ions (millimolar): 145.489039
 - cansr in component intracellular_ions (millimolar): 1.606252
 - cajsr in component intracellular_ions (millimolar): 1.605428
 - cai in component intracellular_ions (millimolar): 0.000088
 - m in component INa (dimensionless): 0.003770
 - hf in component INa (dimensionless): 0.872755
 - hs in component INa (dimensionless): 0.872756
 - j in component INa (dimensionless): 0.872763
 - hsp in component INa (dimensionless): 0.712354
 - jp in component INa (dimensionless): 0.872766
 - mL in component INaL (dimensionless): 0.000054
 - hL in component INaL (dimensionless): 0.718163
 - hLp in component INaL (dimensionless): 0.510042
 - a in component Ito (dimensionless): 0.000641
 - iF in component Ito (dimensionless): 0.999860
 - iS in component Ito (dimensionless): 0.892259
 - ap in component Ito (dimensionless): 0.000326
 - iFp in component Ito (dimensionless): 0.999860
 - iSp in component Ito (dimensionless): 0.931958
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.975861
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002834
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.098166
 - xs1 in component IKs (dimensionless): 0.123565
 - xs2 in component IKs (dimensionless): 0.000092
 - xk1 in component IK1 (dimensionless): 0.997442
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:08:21 (30832): called boinc_finish(0)

</stderr_txt>
]]>


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