𝕏

Task 55226482

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_2000-conf_376_1
Workunit 26226829
Created 28 Jun 2024, 6:10:25 UTC
Sent 29 Jun 2024, 6:07:36 UTC
Report deadline 2 Jul 2024, 6:07:36 UTC
Received 1 Jul 2024, 23:44:47 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213646
Run time 1 hours 53 min 18 sec
CPU time 1 hours 41 min 31 sec
Validate state Valid
Credit 41.92
Device peak FLOPS 3.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.21 MB
Peak swap size 33.04 GB
Peak disk usage 0.64 MB

Stderr output

<core_client_version>8.0.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_2000-conf_376.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_2000-conf_376_1_r1034371035_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_2000-conf_376_1_r1034371035_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 91.561615
     * GNaL_b in INaL: 0.005610
     * Gto_b in Ito: 0.074088
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032819
     * GKs_b in IKs: 0.002135
     * GK1_b in IK1: 0.163435
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 69.254525
     * GKb_b in IKb: 0.003891
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036784
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 7223027, states[0] = -94.601989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 14888802, states[0] = -94.841690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23354828, states[0] = -94.705579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34568253, states[0] = -94.768869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45189307, states[0] = -93.849211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56420745, states[0] = -94.700410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67345847, states[0] = -94.633722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77016567, states[0] = 27.581458, states[40]= 0.006145
Saving checkpoint... 
Iteration: 88190431, states[0] = -93.734834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98391047, states[0] = -94.665546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109238494, states[0] = -94.403634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119889391, states[0] = -94.734918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130376142, states[0] = -94.649635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140718218, states[0] = -94.734070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150491586, states[0] = -94.707954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161866863, states[0] = -94.732504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173120824, states[0] = -22.931602, states[40]= 0.001248
Saving checkpoint... 
Iteration: 184132651, states[0] = -33.457203, states[40]= 0.000775
Saving checkpoint... 
Iteration: 195060399, states[0] = 15.720765, states[40]= 0.003364
Saving checkpoint... 
Iteration: 205780655, states[0] = -94.732413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216033128, states[0] = 24.609825, states[40]= 0.001787
Saving checkpoint... 
Iteration: 227186139, states[0] = -92.160280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238458735, states[0] = -94.695069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249287281, states[0] = -94.526534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259601498, states[0] = -94.725582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269870552, states[0] = -94.730938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280376893, states[0] = -94.646937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291027525, states[0] = 26.011469, states[40]= 0.001696
Saving checkpoint... 
Iteration: 302355685, states[0] = -94.627118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312421293, states[0] = -94.677288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323262921, states[0] = -94.469848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333739088, states[0] = -94.731617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344552199, states[0] = -94.719055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351684540, states[0] = -94.730449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359664116, states[0] = -94.729630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370666411, states[0] = -94.729711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381608833, states[0] = -94.725940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388973655, states[0] = -94.728390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399618983, states[0] = -94.726767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410633547, states[0] = -94.727819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421410359, states[0] = -94.670699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432478227, states[0] = -94.701493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442959460, states[0] = -94.728634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450548726, states[0] = -94.718279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460322017, states[0] = -94.585708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471097232, states[0] = -2.517926, states[40]= 0.004013
Saving checkpoint... 
Iteration: 481893382, states[0] = -94.730035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492700127, states[0] = -94.730640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503071223, states[0] = 11.409661, states[40]= 0.004027
Saving checkpoint... 
Iteration: 513908608, states[0] = -94.729663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524668849, states[0] = -94.729529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535224815, states[0] = -94.349576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546357284, states[0] = -94.628268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557586877, states[0] = -94.723388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568664838, states[0] = -94.729273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579360292, states[0] = -94.631213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590358398, states[0] = -94.629311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600838282, states[0] = -94.730758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611561424, states[0] = -94.719980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622221211, states[0] = -94.335996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633205880, states[0] = -94.270398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643933224, states[0] = -94.728882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653828372, states[0] = -94.730788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665017033, states[0] = 27.645573, states[40]= 0.005480
Saving checkpoint... 
Iteration: 675595133, states[0] = -94.724071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686629116, states[0] = -94.727005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697496744, states[0] = -94.706555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708202115, states[0] = -94.242337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719486665, states[0] = -94.703614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730739158, states[0] = -94.730876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741113251, states[0] = -15.992008, states[40]= 0.001525
Saving checkpoint... 
Iteration: 752490361, states[0] = -94.704649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763137176, states[0] = -37.504290, states[40]= 0.000495
Saving checkpoint... 
Iteration: 773525337, states[0] = -94.713298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784539077, states[0] = -94.715976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795671054, states[0] = -94.729125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806089554, states[0] = 2.357101, states[40]= 0.004470
Saving checkpoint... 
Iteration: 817031406, states[0] = 25.070601, states[40]= 0.001738
Saving checkpoint... 
Iteration: 827754485, states[0] = -94.730808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838753938, states[0] = -94.730785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850030214, states[0] = 25.373728, states[40]= 0.001712
Saving checkpoint... 
Iteration: 861608686, states[0] = -94.725045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872882638, states[0] = -94.729530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884539558, states[0] = -94.715882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895268993, states[0] = -94.484168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906674561, states[0] = -94.729063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917161005, states[0] = -60.677986, states[40]= 0.000015
Saving checkpoint... 
Iteration: 924285076, states[0] = -94.520594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931105220, states[0] = -8.759404, states[40]= 0.002771
Saving checkpoint... 
Iteration: 938098058, states[0] = -3.102766, states[40]= 0.003921
Saving checkpoint... 
Iteration: 948815085, states[0] = -94.730395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959790976, states[0] = -94.730554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970976618, states[0] = -94.727249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977860986, states[0] = -94.729724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988854585, states[0] = -94.729808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000191188, states[0] = -93.722696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010629654, states[0] = -94.726451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021773525, states[0] = -94.730490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029626355, states[0] = -94.726179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036679752, states[0] = -94.729021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047204989, states[0] = -94.264189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058227757, states[0] = -94.359305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069695371, states[0] = -94.729459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080642298, states[0] = -94.727153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092061670, states[0] = 15.253343, states[40]= 0.003450
Saving checkpoint... 
Iteration: 1103125768, states[0] = -27.271149, states[40]= 0.001181
Saving checkpoint... 
Iteration: 1114602982, states[0] = -94.724054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124915906, states[0] = -94.728389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135932407, states[0] = -94.728002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146861295, states[0] = -94.729411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158274609, states[0] = -94.497105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169380274, states[0] = -94.648037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180879808, states[0] = -94.729020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191730362, states[0] = -94.729935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202544236, states[0] = -94.716137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213958508, states[0] = -94.727247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224630376, states[0] = -94.726111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235113292, states[0] = -16.028851, states[40]= 0.001521
Saving checkpoint... 
Iteration: 1245864768, states[0] = -94.729171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256886941, states[0] = -94.728745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268036486, states[0] = 23.669571, states[40]= 0.001916
Saving checkpoint... 
Iteration: 1279325726, states[0] = -94.589426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290242595, states[0] = -94.409223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301665422, states[0] = -94.727960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313006586, states[0] = 28.762396, states[40]= 0.144588
Saving checkpoint... 
Iteration: 1324963781, states[0] = -94.726916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336858662, states[0] = -94.729107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348092622, states[0] = 0.520552, states[40]= 0.004365
Saving checkpoint... 
Iteration: 1360308839, states[0] = -94.563831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371758601, states[0] = -94.729831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381835500, states[0] = -94.729368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392580555, states[0] = -94.721119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404026309, states[0] = 26.277913, states[40]= 0.001720
Saving checkpoint... 
Iteration: 1414445539, states[0] = -94.687245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425234711, states[0] = -94.382993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436737517, states[0] = -94.729570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448324909, states[0] = -94.587981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460209576, states[0] = -94.287598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471298142, states[0] = -94.545113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483097253, states[0] = -2.531360, states[40]= 0.004011
Saving checkpoint... 
Iteration: 1494711290, states[0] = -94.729066, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.601633
 - CaMKt in component CaMK (millimolar): 0.004115
 - cass in component intracellular_ions (millimolar): 0.000084
 - nai in component intracellular_ions (millimolar): 6.460627
 - nass in component intracellular_ions (millimolar): 6.460712
 - ki in component intracellular_ions (millimolar): 145.454085
 - kss in component intracellular_ions (millimolar): 145.454069
 - cansr in component intracellular_ions (millimolar): 1.577982
 - cajsr in component intracellular_ions (millimolar): 1.577231
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.003730
 - hf in component INa (dimensionless): 0.874692
 - hs in component INa (dimensionless): 0.874693
 - j in component INa (dimensionless): 0.874699
 - hsp in component INa (dimensionless): 0.715937
 - jp in component INa (dimensionless): 0.874702
 - mL in component INaL (dimensionless): 0.000052
 - hL in component INaL (dimensionless): 0.721041
 - hLp in component INaL (dimensionless): 0.513940
 - a in component Ito (dimensionless): 0.000636
 - iF in component Ito (dimensionless): 0.999863
 - iS in component Ito (dimensionless): 0.893456
 - ap in component Ito (dimensionless): 0.000324
 - iFp in component Ito (dimensionless): 0.999863
 - iSp in component Ito (dimensionless): 0.933075
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.976039
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002650
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.096160
 - xs1 in component IKs (dimensionless): 0.122751
 - xs2 in component IKs (dimensionless): 0.000091
 - xk1 in component IK1 (dimensionless): 0.997415
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:58:41 (31584): called boinc_finish(0)

</stderr_txt>
]]>


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