𝕏

Task 55225895

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_ENDO_6000-conf_575_0
Workunit 26226536
Created 28 Jun 2024, 6:10:09 UTC
Sent 29 Jun 2024, 6:07:36 UTC
Report deadline 2 Jul 2024, 6:07:36 UTC
Received 30 Jun 2024, 2:09:31 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213646
Run time 2 hours 26 min 20 sec
CPU time 1 hours 56 min 47 sec
Validate state Valid
Credit 44.52
Device peak FLOPS 3.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.77 MB
Peak swap size 32.79 GB
Peak disk usage 0.04 MB

Stderr output

<core_client_version>8.0.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_ENDO_6000-conf_575.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_ENDO_6000-conf_575_0_r829414065_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_ENDO_6000-conf_575_0_r829414065_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 119.950622
     * GNaL_b in INaL: 0.005333
     * Gto_b in Ito: 0.091540
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030361
     * GKs_b in IKs: 0.001981
     * GK1_b in IK1: 0.147206
     * Gncx_b in INaCa_i: 0.000957
     * Pnak_b in INaK: 73.385133
     * GKb_b in IKb: 0.003680
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.018633
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 6002225, states[0] = 43.453864, states[40]= 0.378740
Saving checkpoint... 
Iteration: 16959968, states[0] = -93.686252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27062680, states[0] = 20.402097, states[40]= 0.001197
Saving checkpoint... 
Iteration: 37960102, states[0] = -93.585612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47989754, states[0] = -93.559634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57379027, states[0] = -93.430089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67153922, states[0] = -93.583958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76419350, states[0] = -93.571156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88773734, states[0] = -93.559485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100905955, states[0] = -93.555751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112291011, states[0] = -93.572810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123197847, states[0] = -61.862004, states[40]= 0.000043
Saving checkpoint... 
Iteration: 134143652, states[0] = -93.550461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143449519, states[0] = -93.546380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155064164, states[0] = -93.551361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166006722, states[0] = -93.584587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177576504, states[0] = -93.574335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188467658, states[0] = -93.545732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199084206, states[0] = -93.580664, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_ENDO_6000-conf_575.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_ENDO_6000-conf_575_0_r829414065_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_ENDO_6000-conf_575_0_r829414065_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 119.950622
     * GNaL_b in INaL: 0.005333
     * Gto_b in Ito: 0.091540
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030361
     * GKs_b in IKs: 0.001981
     * GK1_b in IK1: 0.147206
     * Gncx_b in INaCa_i: 0.000957
     * Pnak_b in INaK: 73.385133
     * GKb_b in IKb: 0.003680
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.018633
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 199084206
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.580664 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 208067803, states[0] = -93.581408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217613888, states[0] = -93.560555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230171956, states[0] = -93.549246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241059175, states[0] = -93.581716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251719788, states[0] = -93.543127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260458865, states[0] = -93.545580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269536661, states[0] = -93.544756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278426145, states[0] = -93.545901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287605635, states[0] = -93.544058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297023132, states[0] = 31.102921, states[40]= 0.000731
Saving checkpoint... 
Iteration: 306398218, states[0] = -93.449095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315450817, states[0] = -93.509574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325219831, states[0] = -93.574153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333913585, states[0] = -93.588257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343100636, states[0] = -93.579546, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_ENDO_6000-conf_575.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_ENDO_6000-conf_575_0_r829414065_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_ENDO_6000-conf_575_0_r829414065_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 119.950622
     * GNaL_b in INaL: 0.005333
     * Gto_b in Ito: 0.091540
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030361
     * GKs_b in IKs: 0.001981
     * GK1_b in IK1: 0.147206
     * Gncx_b in INaCa_i: 0.000957
     * Pnak_b in INaK: 73.385133
     * GKb_b in IKb: 0.003680
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.018633
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 343100636
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.579546 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 353211998, states[0] = -93.548436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363591305, states[0] = -93.577344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375232475, states[0] = -91.402518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384456206, states[0] = -93.514106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392916129, states[0] = -93.541383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401977052, states[0] = -93.540958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414320259, states[0] = -93.277125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424922015, states[0] = -93.553060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435343491, states[0] = -93.342733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447125710, states[0] = -10.845817, states[40]= 0.002574
Saving checkpoint... 
Iteration: 458670128, states[0] = -93.543194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469072466, states[0] = -93.580683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479823417, states[0] = -93.541915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490623902, states[0] = -93.559779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500495634, states[0] = -93.544788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511471574, states[0] = -93.564295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521507526, states[0] = -93.544632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531178425, states[0] = -48.280251, states[40]= 0.000369
Saving checkpoint... 
Iteration: 542866669, states[0] = -93.541494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555329338, states[0] = -93.304368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567180229, states[0] = -49.549581, states[40]= 0.000307
Saving checkpoint... 
Iteration: 578776238, states[0] = -93.542121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588499907, states[0] = -93.543786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602166794, states[0] = -93.548681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615042756, states[0] = 27.173043, states[40]= 0.000285
Saving checkpoint... 
Iteration: 627456104, states[0] = -93.513632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638918399, states[0] = -93.540974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649194437, states[0] = -93.574747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664905748, states[0] = -93.552992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678107125, states[0] = 1.606014, states[40]= 0.004118
Saving checkpoint... 
Iteration: 687909295, states[0] = -93.587869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699389473, states[0] = -93.435080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709594829, states[0] = -93.560235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719964362, states[0] = -93.540533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731704014, states[0] = -93.542467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745076254, states[0] = -93.580063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756373948, states[0] = -93.408232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767432942, states[0] = -93.545033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778352773, states[0] = -93.568043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789753780, states[0] = -93.591211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802648200, states[0] = -93.558631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813950354, states[0] = -93.585898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826922270, states[0] = -93.552414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838349350, states[0] = -93.568077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850055083, states[0] = -93.580909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863188480, states[0] = -93.547952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874236514, states[0] = -93.572559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885985926, states[0] = -93.584146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897945979, states[0] = -93.585960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910078364, states[0] = -93.579701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921739609, states[0] = -93.590829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932915151, states[0] = -93.540528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943519085, states[0] = -93.562097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956234265, states[0] = -93.547167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966614742, states[0] = -93.580887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978320740, states[0] = -93.277729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991514913, states[0] = -93.562150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004414191, states[0] = -93.544864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017130246, states[0] = -14.364500, states[40]= 0.002055
Saving checkpoint... 
Iteration: 1028751813, states[0] = -93.541598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040704171, states[0] = -93.541973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052949416, states[0] = -93.540102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064700161, states[0] = -93.541969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078073295, states[0] = -93.579675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089781148, states[0] = -93.590742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103209156, states[0] = -93.547278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116452222, states[0] = -93.509527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127603631, states[0] = -93.542727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139584678, states[0] = -93.542886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151632451, states[0] = -93.542423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164035246, states[0] = 29.106694, states[40]= 0.000197
Saving checkpoint... 
Iteration: 1175983557, states[0] = -93.539680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187477927, states[0] = -93.543878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199350904, states[0] = -93.545289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208294017, states[0] = -93.545979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219858578, states[0] = -93.553052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232823756, states[0] = -93.540711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245670819, states[0] = -93.587195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258411496, states[0] = -93.565143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271975828, states[0] = -93.539577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282456086, states[0] = -93.563578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292383321, states[0] = -93.544758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303302623, states[0] = -93.569150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314166859, states[0] = -40.131856, states[40]= 0.001081
Saving checkpoint... 
Iteration: 1326878876, states[0] = -93.588035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338591059, states[0] = -93.575741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350049951, states[0] = 25.019515, states[40]= 0.000427
Saving checkpoint... 
Iteration: 1363907227, states[0] = -93.551849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377094314, states[0] = 8.056987, states[40]= 0.003247
Saving checkpoint... 
Iteration: 1389127975, states[0] = -12.599059, states[40]= 0.002276
Saving checkpoint... 
Iteration: 1406369165, states[0] = -93.544742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420845201, states[0] = -93.553010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434473684, states[0] = -93.525957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448960259, states[0] = -93.539398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460274896, states[0] = -93.545823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471297646, states[0] = -93.569081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485476635, states[0] = -93.527944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499247423, states[0] = -93.546123, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.415035
 - CaMKt in component CaMK (millimolar): 0.001351
 - cass in component intracellular_ions (millimolar): 0.000103
 - nai in component intracellular_ions (millimolar): 6.654975
 - nass in component intracellular_ions (millimolar): 6.655101
 - ki in component intracellular_ions (millimolar): 145.205551
 - kss in component intracellular_ions (millimolar): 145.205542
 - cansr in component intracellular_ions (millimolar): 1.853860
 - cajsr in component intracellular_ions (millimolar): 1.853746
 - cai in component intracellular_ions (millimolar): 0.000107
 - m in component INa (dimensionless): 0.004204
 - hf in component INa (dimensionless): 0.851715
 - hs in component INa (dimensionless): 0.851716
 - j in component INa (dimensionless): 0.851717
 - hsp in component INa (dimensionless): 0.674673
 - jp in component INa (dimensionless): 0.851718
 - mL in component INaL (dimensionless): 0.000066
 - hL in component INaL (dimensionless): 0.688240
 - hLp in component INaL (dimensionless): 0.491020
 - a in component Ito (dimensionless): 0.000689
 - iF in component Ito (dimensionless): 0.999831
 - iS in component Ito (dimensionless): 0.999176
 - ap in component Ito (dimensionless): 0.000351
 - iFp in component Ito (dimensionless): 0.999831
 - iSp in component Ito (dimensionless): 0.999673
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999514
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005718
 - xrf in component IKr (dimensionless): 0.000004
 - xrs in component IKr (dimensionless): 0.000664
 - xs1 in component IKs (dimensionless): 0.014930
 - xs2 in component IKs (dimensionless): 0.000104
 - xk1 in component IK1 (dimensionless): 0.997701
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:59:12 (8699): called boinc_finish(0)

</stderr_txt>
]]>


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