𝕏

Task 55225625

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-BASE_MID-conf_575_0
Workunit 26226401
Created 28 Jun 2024, 6:09:59 UTC
Sent 29 Jun 2024, 6:00:12 UTC
Report deadline 2 Jul 2024, 6:00:12 UTC
Received 29 Jun 2024, 8:23:10 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232674
Run time 1 hours 46 min 14 sec
CPU time 1 hours 44 min 17 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 5.37 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.66 MB
Peak swap size 32.60 GB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-BASE_MID-conf_575.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-BASE_MID-conf_575_0_r720483668_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-BASE_MID-conf_575_0_r720483668_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 119.950622
     * GNaL_b in INaL: 0.005333
     * Gto_b in Ito: 0.091540
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030361
     * GKs_b in IKs: 0.001981
     * GK1_b in IK1: 0.147206
     * Gncx_b in INaCa_i: 0.000957
     * Pnak_b in INaK: 73.385133
     * GKb_b in IKb: 0.003680
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.018633
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 15699874, states[0] = -58.766601, states[40]= 0.000025
Saving checkpoint... 
Iteration: 31870081, states[0] = -86.660707, states[40]= 0.000002
Saving checkpoint... 
Iteration: 48441623, states[0] = -86.778999, states[40]= 0.000002
Saving checkpoint... 
Iteration: 64944982, states[0] = -86.807788, states[40]= 0.000002
Saving checkpoint... 
Iteration: 79751990, states[0] = -86.327363, states[40]= 0.000001
Saving checkpoint... 
Iteration: 97092772, states[0] = 10.082078, states[40]= 0.000027
Saving checkpoint... 
Iteration: 113037470, states[0] = 30.117335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129025986, states[0] = 31.346572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145435409, states[0] = -86.838197, states[40]= 0.000002
Saving checkpoint... 
Iteration: 160640556, states[0] = -22.006063, states[40]= 0.000517
Saving checkpoint... 
Iteration: 177670703, states[0] = -47.415767, states[40]= 0.000241
Saving checkpoint... 
Iteration: 194403619, states[0] = -86.809443, states[40]= 0.000002
Saving checkpoint... 
Iteration: 209471026, states[0] = -86.860009, states[40]= 0.000002
Saving checkpoint... 
Iteration: 226212861, states[0] = -85.911552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243064507, states[0] = 21.961893, states[40]= 0.000001
Saving checkpoint... 
Iteration: 257835132, states[0] = -86.693273, states[40]= 0.000002
Saving checkpoint... 
Iteration: 274396854, states[0] = -86.797823, states[40]= 0.000002
Saving checkpoint... 
Iteration: 290083040, states[0] = 14.248911, states[40]= 0.000010
Saving checkpoint... 
Iteration: 306322210, states[0] = -86.656891, states[40]= 0.000002
Saving checkpoint... 
Iteration: 321284592, states[0] = -86.522469, states[40]= 0.000002
Saving checkpoint... 
Iteration: 338417522, states[0] = -86.815615, states[40]= 0.000002
Saving checkpoint... 
Iteration: 353574736, states[0] = 17.863677, states[40]= 0.000004
Saving checkpoint... 
Iteration: 370149126, states[0] = -28.655548, states[40]= 0.000874
Saving checkpoint... 
Iteration: 386421265, states[0] = -86.816108, states[40]= 0.000002
Saving checkpoint... 
Iteration: 401408195, states[0] = -86.802658, states[40]= 0.000002
Saving checkpoint... 
Iteration: 418463649, states[0] = -86.844064, states[40]= 0.000002
Saving checkpoint... 
Iteration: 433951879, states[0] = -86.836223, states[40]= 0.000002
Saving checkpoint... 
Iteration: 449918235, states[0] = -86.809500, states[40]= 0.000002
Saving checkpoint... 
Iteration: 467533536, states[0] = 30.678580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483147885, states[0] = -27.685044, states[40]= 0.000851
Saving checkpoint... 
Iteration: 498730678, states[0] = -86.174418, states[40]= 0.000001
Saving checkpoint... 
Iteration: 516538242, states[0] = 29.882545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531483464, states[0] = -86.846918, states[40]= 0.000002
Saving checkpoint... 
Iteration: 548784307, states[0] = -86.507138, states[40]= 0.000001
Saving checkpoint... 
Iteration: 564775571, states[0] = -86.465105, states[40]= 0.000001
Saving checkpoint... 
Iteration: 579606411, states[0] = 2.806177, states[40]= 0.000110
Saving checkpoint... 
Iteration: 594632639, states[0] = -15.817558, states[40]= 0.000290
Saving checkpoint... 
Iteration: 610058266, states[0] = 24.245451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626732897, states[0] = -86.184923, states[40]= 0.000001
Saving checkpoint... 
Iteration: 643932985, states[0] = -86.810295, states[40]= 0.000002
Saving checkpoint... 
Iteration: 658878179, states[0] = -86.750090, states[40]= 0.000002
Saving checkpoint... 
Iteration: 674265273, states[0] = -86.403922, states[40]= 0.000001
Saving checkpoint... 
Iteration: 691786854, states[0] = -86.509471, states[40]= 0.000002
Saving checkpoint... 
Iteration: 707561099, states[0] = 23.237785, states[40]= 0.000001
Saving checkpoint... 
Iteration: 722488953, states[0] = -86.837679, states[40]= 0.000002
Saving checkpoint... 
Iteration: 738365225, states[0] = -86.724948, states[40]= 0.000002
Saving checkpoint... 
Iteration: 755318792, states[0] = -86.619646, states[40]= 0.000002
Saving checkpoint... 
Iteration: 770162713, states[0] = -40.003560, states[40]= 0.000508
Saving checkpoint... 
Iteration: 786494645, states[0] = -86.836071, states[40]= 0.000002
Saving checkpoint... 
Iteration: 803745249, states[0] = -86.268499, states[40]= 0.000001
Saving checkpoint... 
Iteration: 818876425, states[0] = -86.737787, states[40]= 0.000002
Saving checkpoint... 
Iteration: 833491322, states[0] = -86.831940, states[40]= 0.000002
Saving checkpoint... 
Iteration: 849734566, states[0] = -86.184470, states[40]= 0.000001
Saving checkpoint... 
Iteration: 867531949, states[0] = 30.894627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883416349, states[0] = -86.781528, states[40]= 0.000002
Saving checkpoint... 
Iteration: 898957834, states[0] = -86.811761, states[40]= 0.000002
Saving checkpoint... 
Iteration: 916654566, states[0] = -32.963189, states[40]= 0.000818
Saving checkpoint... 
Iteration: 933088907, states[0] = 11.582673, states[40]= 0.000020
Saving checkpoint... 
Iteration: 948707799, states[0] = -85.379394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966000172, states[0] = -65.681551, states[40]= 0.000002
Saving checkpoint... 
Iteration: 982171891, states[0] = -48.593427, states[40]= 0.000209
Saving checkpoint... 
Iteration: 998255257, states[0] = -86.323842, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1015837899, states[0] = -86.653655, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1031208801, states[0] = -85.523029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049318837, states[0] = -86.601759, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1064760903, states[0] = -86.354390, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1080441433, states[0] = -86.790181, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1098631718, states[0] = -15.008028, states[40]= 0.000281
Saving checkpoint... 
Iteration: 1113686559, states[0] = -64.003148, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1131314283, states[0] = -86.583052, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1147342674, states[0] = -86.656447, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1163757778, states[0] = -86.329328, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1181269687, states[0] = -86.396656, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1196594205, states[0] = 9.076002, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1211365660, states[0] = -86.696908, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1228687109, states[0] = -64.645242, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1245861750, states[0] = -86.688065, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1261290797, states[0] = -86.491018, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1277228429, states[0] = -86.105786, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1294908287, states[0] = -86.748653, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1310855073, states[0] = -86.671892, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1326790734, states[0] = -86.486706, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1343568456, states[0] = 20.455004, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1360675256, states[0] = -51.851993, states[40]= 0.000140
Saving checkpoint... 
Iteration: 1375840533, states[0] = -86.637712, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1393997986, states[0] = -86.800709, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1410059635, states[0] = 23.782634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426644375, states[0] = -24.930802, states[40]= 0.000705
Saving checkpoint... 
Iteration: 1444315406, states[0] = -86.567327, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1459610045, states[0] = 0.805706, states[40]= 0.000143
Saving checkpoint... 
Iteration: 1475681750, states[0] = -58.505910, states[40]= 0.000059
Saving checkpoint... 
Iteration: 1493651909, states[0] = -30.746569, states[40]= 0.000864
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.670897
 - CaMKt in component CaMK (millimolar): 0.026339
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 8.016316
 - nass in component intracellular_ions (millimolar): 8.016474
 - ki in component intracellular_ions (millimolar): 143.325420
 - kss in component intracellular_ions (millimolar): 143.325382
 - cansr in component intracellular_ions (millimolar): 2.130611
 - cajsr in component intracellular_ions (millimolar): 2.070305
 - cai in component intracellular_ions (millimolar): 0.000098
 - m in component INa (dimensionless): 0.008291
 - hf in component INa (dimensionless): 0.654752
 - hs in component INa (dimensionless): 0.654718
 - j in component INa (dimensionless): 0.654519
 - hsp in component INa (dimensionless): 0.406312
 - jp in component INa (dimensionless): 0.654375
 - mL in component INaL (dimensionless): 0.000237
 - hL in component INaL (dimensionless): 0.450050
 - hLp in component INaL (dimensionless): 0.216495
 - a in component Ito (dimensionless): 0.001086
 - iF in component Ito (dimensionless): 0.999449
 - iS in component Ito (dimensionless): 0.528757
 - ap in component Ito (dimensionless): 0.000553
 - iFp in component Ito (dimensionless): 0.999449
 - iSp in component Ito (dimensionless): 0.571274
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.875470
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999600
 - jca in component ICaL (dimensionless): 0.999937
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004214
 - xrf in component IKr (dimensionless): 0.000011
 - xrs in component IKr (dimensionless): 0.514880
 - xs1 in component IKs (dimensionless): 0.336726
 - xs2 in component IKs (dimensionless): 0.000221
 - xk1 in component IK1 (dimensionless): 0.997062
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
10:16:48 (60203): called boinc_finish(0)

</stderr_txt>
]]>