𝕏

Task 55224257

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_1000-conf_273_0
Workunit 26225721
Created 28 Jun 2024, 6:09:26 UTC
Sent 29 Jun 2024, 5:52:22 UTC
Report deadline 2 Jul 2024, 5:52:22 UTC
Received 29 Jun 2024, 13:44:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213791
Run time 1 hours 58 min 3 sec
CPU time 1 hours 58 min 3 sec
Validate state Valid
Credit 44.06
Device peak FLOPS 3.69 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.63 MB
Peak swap size 6.21 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_1000-conf_273.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_1000-conf_273_0_r2020854027_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_1000-conf_273_0_r2020854027_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 99.907757
     * GNaL_b in INaL: 0.004917
     * Gto_b in Ito: 0.089831
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030045
     * GKs_b in IKs: 0.002135
     * GK1_b in IK1: 0.153605
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 70.175797
     * GKb_b in IKb: 0.003797
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025496
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11286756, states[0] = -94.712259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24632972, states[0] = -43.489259, states[40]= 0.000228
Saving checkpoint... 
Iteration: 38267989, states[0] = -94.589274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51549866, states[0] = 17.505095, states[40]= 0.002188
Saving checkpoint... 
Iteration: 65129972, states[0] = -39.692670, states[40]= 0.000401
Saving checkpoint... 
Iteration: 77722682, states[0] = -94.431805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89943771, states[0] = -94.779186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103242384, states[0] = -94.503657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115526103, states[0] = 25.555062, states[40]= 0.001165
Saving checkpoint... 
Iteration: 128371129, states[0] = -94.734842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138819935, states[0] = -94.677809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151829547, states[0] = -94.690759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163531942, states[0] = 23.918742, states[40]= 0.001197
Saving checkpoint... 
Iteration: 176228386, states[0] = -94.451887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189432696, states[0] = -94.772555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201736559, states[0] = -94.482077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214779938, states[0] = -94.605258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227257745, states[0] = -94.549427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240228448, states[0] = -94.451721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252046040, states[0] = 19.022676, states[40]= 0.001922
Saving checkpoint... 
Iteration: 265414030, states[0] = -94.762911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276749355, states[0] = -94.524278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290031663, states[0] = 24.006200, states[40]= 0.001189
Saving checkpoint... 
Iteration: 300648107, states[0] = -57.131885, states[40]= 0.000032
Saving checkpoint... 
Iteration: 312755029, states[0] = -94.541188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325482577, states[0] = -94.789294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337572535, states[0] = 7.754825, states[40]= 0.003986
Saving checkpoint... 
Iteration: 349556127, states[0] = 15.090240, states[40]= 0.002689
Saving checkpoint... 
Iteration: 361745410, states[0] = -94.511352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374545233, states[0] = 19.324369, states[40]= 0.001868
Saving checkpoint... 
Iteration: 387935759, states[0] = -94.772895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400534616, states[0] = 23.069450, states[40]= 0.001294
Saving checkpoint... 
Iteration: 413856775, states[0] = -94.719998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426595116, states[0] = -6.946746, states[40]= 0.003258
Saving checkpoint... 
Iteration: 439656829, states[0] = -66.236991, states[40]= 0.000007
Saving checkpoint... 
Iteration: 451002528, states[0] = 39.997623, states[40]= 0.520089
Saving checkpoint... 
Iteration: 464220153, states[0] = -94.417185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476552288, states[0] = 16.625246, states[40]= 0.002380
Saving checkpoint... 
Iteration: 489625828, states[0] = -35.669289, states[40]= 0.000640
Saving checkpoint... 
Iteration: 502024351, states[0] = 25.976232, states[40]= 0.001280
Saving checkpoint... 
Iteration: 514538717, states[0] = 21.679778, states[40]= 0.001485
Saving checkpoint... 
Iteration: 527315101, states[0] = -94.668490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539763261, states[0] = -94.563079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553246077, states[0] = -94.512595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564839078, states[0] = -94.700332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578352532, states[0] = -94.714993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590011999, states[0] = 27.188876, states[40]= 0.025739
Saving checkpoint... 
Iteration: 601489370, states[0] = -94.789743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612269994, states[0] = -94.580033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623899223, states[0] = -94.752551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635632766, states[0] = -42.167573, states[40]= 0.000294
Saving checkpoint... 
Iteration: 648734766, states[0] = -94.473447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660502665, states[0] = 39.115007, states[40]= 0.514145
Saving checkpoint... 
Iteration: 672541804, states[0] = 20.582889, states[40]= 0.001655
Saving checkpoint... 
Iteration: 685744572, states[0] = -94.507083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698058329, states[0] = 14.185647, states[40]= 0.002873


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_1000-conf_273.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_1000-conf_273_0_r2020854027_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_1000-conf_273_0_r2020854027_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 99.907757
     * GNaL_b in INaL: 0.004917
     * Gto_b in Ito: 0.089831
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030045
     * GKs_b in IKs: 0.002135
     * GK1_b in IK1: 0.153605
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 70.175797
     * GKb_b in IKb: 0.003797
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025496
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 698058329
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 14.185647 (After loading)
 - states[40]: 0.002873 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 711464431, states[0] = -94.782155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724409680, states[0] = -94.758336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737705933, states[0] = -94.351767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750391609, states[0] = -94.746963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763201894, states[0] = -94.330701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775368167, states[0] = -94.728781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787633638, states[0] = -42.997157, states[40]= 0.000263
Saving checkpoint... 
Iteration: 800317642, states[0] = -94.670996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812894241, states[0] = -94.748440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825617932, states[0] = -28.389329, states[40]= 0.001121
Saving checkpoint... 
Iteration: 838544092, states[0] = 19.747844, states[40]= 0.001795
Saving checkpoint... 
Iteration: 851948667, states[0] = -94.775968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864154733, states[0] = -63.936979, states[40]= 0.000010
Saving checkpoint... 
Iteration: 873501290, states[0] = 47.072398, states[40]= 0.298183
Saving checkpoint... 
Iteration: 885747237, states[0] = -94.514726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898340213, states[0] = -94.700086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909870790, states[0] = -94.730393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922377318, states[0] = -94.735663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934931034, states[0] = -94.768227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947468522, states[0] = -94.782341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959036553, states[0] = 22.424917, states[40]= 0.001379
Saving checkpoint... 
Iteration: 970814599, states[0] = -94.665637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983201784, states[0] = -94.329035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995240745, states[0] = -94.492833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005600129, states[0] = -11.533344, states[40]= 0.002285
Saving checkpoint... 
Iteration: 1017500830, states[0] = 43.714145, states[40]= 0.098039
Saving checkpoint... 
Iteration: 1027490928, states[0] = -94.788128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038689296, states[0] = -94.180053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049760082, states[0] = -94.552037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062830928, states[0] = -94.688002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074903076, states[0] = -94.752817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087184803, states[0] = -93.931168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099707949, states[0] = -94.359792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111230364, states[0] = -94.454900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123841732, states[0] = -94.700772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136737468, states[0] = -94.480795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146643030, states[0] = -52.109552, states[40]= 0.000071
Saving checkpoint... 
Iteration: 1158451277, states[0] = -94.775510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171774130, states[0] = -94.587391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184413059, states[0] = -94.758060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196317077, states[0] = -94.668294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208948236, states[0] = -94.774130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220916343, states[0] = -94.759658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232664152, states[0] = -75.347804, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1244160700, states[0] = -70.792938, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1257395454, states[0] = -94.747153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269949460, states[0] = -94.774308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283312955, states[0] = -94.661640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296431990, states[0] = -94.766964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309047869, states[0] = 18.334390, states[40]= 0.002049
Saving checkpoint... 
Iteration: 1321565665, states[0] = 11.016240, states[40]= 0.003483
Saving checkpoint... 
Iteration: 1333994733, states[0] = -94.787598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346692274, states[0] = -94.244376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357772498, states[0] = -94.582616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371217557, states[0] = -94.401832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383404168, states[0] = -94.752028, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_1000-conf_273.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_1000-conf_273_0_r2020854027_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_1000-conf_273_0_r2020854027_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 99.907757
     * GNaL_b in INaL: 0.004917
     * Gto_b in Ito: 0.089831
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030045
     * GKs_b in IKs: 0.002135
     * GK1_b in IK1: 0.153605
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 70.175797
     * GKb_b in IKb: 0.003797
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025496
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1383404168
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.752028 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1396838258, states[0] = -94.695450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408664395, states[0] = -75.685739, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1421359760, states[0] = -94.718128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431807662, states[0] = -94.652505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442592262, states[0] = -4.551677, states[40]= 0.003734
Saving checkpoint... 
Iteration: 1455902198, states[0] = -94.750494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467872627, states[0] = -94.729306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480788403, states[0] = -94.617162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492987218, states[0] = -94.785026, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.663891
 - CaMKt in component CaMK (millimolar): 0.013343
 - cass in component intracellular_ions (millimolar): 0.000089
 - nai in component intracellular_ions (millimolar): 6.758376
 - nass in component intracellular_ions (millimolar): 6.758476
 - ki in component intracellular_ions (millimolar): 145.108595
 - kss in component intracellular_ions (millimolar): 145.108574
 - cansr in component intracellular_ions (millimolar): 1.709040
 - cajsr in component intracellular_ions (millimolar): 1.667055
 - cai in component intracellular_ions (millimolar): 0.000091
 - m in component INa (dimensionless): 0.003706
 - hf in component INa (dimensionless): 0.875810
 - hs in component INa (dimensionless): 0.875801
 - j in component INa (dimensionless): 0.875743
 - hsp in component INa (dimensionless): 0.717955
 - jp in component INa (dimensionless): 0.875703
 - mL in component INaL (dimensionless): 0.000052
 - hL in component INaL (dimensionless): 0.699744
 - hLp in component INaL (dimensionless): 0.434348
 - a in component Ito (dimensionless): 0.000634
 - iF in component Ito (dimensionless): 0.999864
 - iS in component Ito (dimensionless): 0.607397
 - ap in component Ito (dimensionless): 0.000323
 - iFp in component Ito (dimensionless): 0.999864
 - iSp in component Ito (dimensionless): 0.677444
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.915715
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999832
 - jca in component ICaL (dimensionless): 0.999972
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003294
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.368837
 - xs1 in component IKs (dimensionless): 0.268966
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997399
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:43:13 (14424): called boinc_finish(0)

</stderr_txt>
]]>


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