𝕏

Task 55224254

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_973_1
Workunit 26225719
Created 28 Jun 2024, 6:09:26 UTC
Sent 29 Jun 2024, 5:52:22 UTC
Report deadline 2 Jul 2024, 8:45:10 UTC
Received 29 Jun 2024, 14:08:18 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213791
Run time 2 hours 12 min 32 sec
CPU time 2 hours 12 min 32 sec
Validate state Valid
Credit 49.84
Device peak FLOPS 3.69 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.63 MB
Peak swap size 6.23 MB
Peak disk usage 0.07 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_973.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_973_1_r2074089920_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_973_1_r2074089920_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.110820
     * GNaL_b in INaL: 0.004444
     * Gto_b in Ito: 0.091656
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032587
     * GKs_b in IKs: 0.000100
     * GK1_b in IK1: 0.147011
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 72.508387
     * GKb_b in IKb: 0.003686
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036362
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13354013, states[0] = -94.724919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25177342, states[0] = -93.478060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38272616, states[0] = -94.535386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50337835, states[0] = -94.637633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62551821, states[0] = 16.726588, states[40]= 0.002763
Saving checkpoint... 
Iteration: 75494723, states[0] = -94.721230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88241751, states[0] = -94.431706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101505857, states[0] = 28.444426, states[40]= 0.197203
Saving checkpoint... 
Iteration: 114255379, states[0] = -94.471736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127436017, states[0] = -94.698373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138658901, states[0] = -72.211014, states[40]= 0.000002
Saving checkpoint... 
Iteration: 148676156, states[0] = -92.432538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160144072, states[0] = -55.706211, states[40]= 0.000036
Saving checkpoint... 
Iteration: 172902445, states[0] = -94.680422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184845371, states[0] = -94.633862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197541733, states[0] = 20.536036, states[40]= 0.002065
Saving checkpoint... 
Iteration: 209783501, states[0] = -94.539067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221682884, states[0] = -93.875044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233453477, states[0] = -94.703649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244492427, states[0] = -94.714833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257105283, states[0] = -16.827987, states[40]= 0.001496
Saving checkpoint... 
Iteration: 268467565, states[0] = -94.708092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278842971, states[0] = -94.630673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290460844, states[0] = -94.705878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300848532, states[0] = -94.636552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313438071, states[0] = -94.697391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324466897, states[0] = -94.707647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337834533, states[0] = -94.620659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350235019, states[0] = -94.403893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362999721, states[0] = -94.715944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375479931, states[0] = -94.711158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388060348, states[0] = 13.397039, states[40]= 0.003465
Saving checkpoint... 
Iteration: 400475665, states[0] = -94.709895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412234745, states[0] = -94.402658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422338718, states[0] = -94.625261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434280018, states[0] = -94.530594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447599593, states[0] = -11.163988, states[40]= 0.002388
Saving checkpoint... 
Iteration: 459898254, states[0] = -94.676413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472405435, states[0] = -94.680679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485087312, states[0] = -0.796481, states[40]= 0.004375
Saving checkpoint... 
Iteration: 497940647, states[0] = -94.697685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509767961, states[0] = -94.502136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521419585, states[0] = -94.688107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534896056, states[0] = -94.674720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546760629, states[0] = -94.482939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559442961, states[0] = -94.698355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571255293, states[0] = -94.467977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583311652, states[0] = -94.588312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594794518, states[0] = -94.559181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607775209, states[0] = -94.519101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620582344, states[0] = 2.448705, states[40]= 0.004562
Saving checkpoint... 
Iteration: 633815456, states[0] = -94.593861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646944862, states[0] = -94.698739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658476291, states[0] = -94.709015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671771452, states[0] = -94.510008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683950669, states[0] = -94.700761, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_973.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_973_1_r2074089920_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_973_1_r2074089920_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.110820
     * GNaL_b in INaL: 0.004444
     * Gto_b in Ito: 0.091656
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032587
     * GKs_b in IKs: 0.000100
     * GK1_b in IK1: 0.147011
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 72.508387
     * GKb_b in IKb: 0.003686
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036362
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 683950669
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.700761 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 697597043, states[0] = -8.732629, states[40]= 0.002916
Saving checkpoint... 
Iteration: 708057563, states[0] = 14.548013, states[40]= 0.003243
Saving checkpoint... 
Iteration: 720320110, states[0] = -94.600237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733339851, states[0] = -94.625290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745518110, states[0] = 26.804954, states[40]= 0.004138
Saving checkpoint... 
Iteration: 758700495, states[0] = -94.255609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770406720, states[0] = -94.680201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783358633, states[0] = -94.644574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795863306, states[0] = -94.648806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808581310, states[0] = 3.073033, states[40]= 0.004566
Saving checkpoint... 
Iteration: 821112839, states[0] = -24.333381, states[40]= 0.001165
Saving checkpoint... 
Iteration: 834051052, states[0] = 17.112680, states[40]= 0.002725
Saving checkpoint... 
Iteration: 846500103, states[0] = -82.032757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858813264, states[0] = -94.589650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871722673, states[0] = -94.354928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884432484, states[0] = -94.692675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897774757, states[0] = -94.516863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908149917, states[0] = -61.789982, states[40]= 0.000013
Saving checkpoint... 
Iteration: 919668750, states[0] = -85.924659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932094539, states[0] = -6.469439, states[40]= 0.003420
Saving checkpoint... 
Iteration: 944326845, states[0] = -94.608483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956153144, states[0] = -65.303318, states[40]= 0.000007
Saving checkpoint... 
Iteration: 967933209, states[0] = -94.692650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981074473, states[0] = 6.860692, states[40]= 0.004397
Saving checkpoint... 
Iteration: 993311534, states[0] = -94.586447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005599912, states[0] = -11.472646, states[40]= 0.002325
Saving checkpoint... 
Iteration: 1019054746, states[0] = 15.677950, states[40]= 0.003017
Saving checkpoint... 
Iteration: 1030968527, states[0] = -94.705255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044081844, states[0] = 2.753319, states[40]= 0.004566
Saving checkpoint... 
Iteration: 1055210558, states[0] = -94.302736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068074164, states[0] = 7.020213, states[40]= 0.004383
Saving checkpoint... 
Iteration: 1079839268, states[0] = -94.623202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092476881, states[0] = -94.707407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104900614, states[0] = -94.675231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117266085, states[0] = -94.494905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130304407, states[0] = -94.574425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142723899, states[0] = -94.358704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156053070, states[0] = 16.335253, states[40]= 0.002883
Saving checkpoint... 
Iteration: 1169024212, states[0] = 25.809619, states[40]= 0.001636
Saving checkpoint... 
Iteration: 1182432344, states[0] = -94.691396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194355065, states[0] = -94.639478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207060367, states[0] = 13.390384, states[40]= 0.003467
Saving checkpoint... 
Iteration: 1218870925, states[0] = -94.653628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231983412, states[0] = -94.708572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244622852, states[0] = -34.149133, states[40]= 0.000685
Saving checkpoint... 
Iteration: 1256374054, states[0] = -94.656019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269799190, states[0] = -94.564883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280747699, states[0] = -94.442339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291704313, states[0] = -94.272776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303182363, states[0] = -93.821478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315990989, states[0] = -94.710093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328139351, states[0] = -50.808770, states[40]= 0.000078
Saving checkpoint... 
Iteration: 1340957586, states[0] = -94.700501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353642910, states[0] = -54.476335, states[40]= 0.000044
Saving checkpoint... 
Iteration: 1365861983, states[0] = -94.645282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378311906, states[0] = -94.585441, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_973.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_973_1_r2074089920_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_973_1_r2074089920_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.110820
     * GNaL_b in INaL: 0.004444
     * Gto_b in Ito: 0.091656
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032587
     * GKs_b in IKs: 0.000100
     * GK1_b in IK1: 0.147011
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 72.508387
     * GKb_b in IKb: 0.003686
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036362
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1378311906
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.585441 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1391600862, states[0] = -12.403968, states[40]= 0.002144
Saving checkpoint... 
Iteration: 1402443143, states[0] = -94.694985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415872673, states[0] = -94.654254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428375406, states[0] = -94.656390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441464201, states[0] = -94.702248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454976921, states[0] = -94.705939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467113821, states[0] = -25.293834, states[40]= 0.001146
Saving checkpoint... 
Iteration: 1479229014, states[0] = -94.377155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491925191, states[0] = -94.686872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1505449296, states[0] = -39.342994, states[40]= 0.000452
Saving checkpoint... 
Iteration: 1517880957, states[0] = -0.943778, states[40]= 0.004585
Saving checkpoint... 
Iteration: 1531451567, states[0] = -94.247400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1543107939, states[0] = -15.496508, states[40]= 0.001575
Saving checkpoint... 
Iteration: 1554613199, states[0] = -94.472671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1566712076, states[0] = -94.467592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579214658, states[0] = -93.959073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1591832797, states[0] = -94.332204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1604209206, states[0] = -93.683118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1616494539, states[0] = -94.286913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628333195, states[0] = -94.238324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1640529067, states[0] = -94.204225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1652630471, states[0] = -23.757459, states[40]= 0.001431
Saving checkpoint... 
Iteration: 1663526916, states[0] = -94.211256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1675446505, states[0] = -94.154023, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.061101
 - CaMKt in component CaMK (millimolar): 0.001128
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.342218
 - nass in component intracellular_ions (millimolar): 6.342304
 - ki in component intracellular_ions (millimolar): 145.553027
 - kss in component intracellular_ions (millimolar): 145.553015
 - cansr in component intracellular_ions (millimolar): 1.568548
 - cajsr in component intracellular_ions (millimolar): 1.568598
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003939
 - hf in component INa (dimensionless): 0.864628
 - hs in component INa (dimensionless): 0.864629
 - j in component INa (dimensionless): 0.864630
 - hsp in component INa (dimensionless): 0.697527
 - jp in component INa (dimensionless): 0.864631
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.706443
 - hLp in component INaL (dimensionless): 0.512484
 - a in component Ito (dimensionless): 0.000660
 - iF in component Ito (dimensionless): 0.999849
 - iS in component Ito (dimensionless): 0.997701
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999849
 - iSp in component Ito (dimensionless): 0.999225
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998904
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003012
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001868
 - xs1 in component IKs (dimensionless): 0.022434
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997549
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:03:12 (6576): called boinc_finish(0)

</stderr_txt>
]]>


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