𝕏

Task 55224246

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_673_1
Workunit 26225715
Created 28 Jun 2024, 6:09:26 UTC
Sent 29 Jun 2024, 5:52:22 UTC
Report deadline 2 Jul 2024, 8:45:10 UTC
Received 29 Jun 2024, 12:19:31 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213791
Run time 2 hours 8 min 5 sec
CPU time 2 hours 8 min 5 sec
Validate state Valid
Credit 48.82
Device peak FLOPS 3.69 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.63 MB
Peak swap size 6.22 MB
Peak disk usage 0.06 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_673.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_673_1_r1147343819_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_673_1_r1147343819_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 109.330508
     * GNaL_b in INaL: 0.007131
     * Gto_b in Ito: 0.072762
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030590
     * GKs_b in IKs: 0.000099
     * GK1_b in IK1: 0.164942
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 72.327038
     * GKb_b in IKb: 0.003680
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.026722
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13025569, states[0] = 26.819632, states[40]= 0.003222
Saving checkpoint... 
Iteration: 25588511, states[0] = 1.379187, states[40]= 0.005066
Saving checkpoint... 
Iteration: 39770566, states[0] = -94.655152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52937294, states[0] = -94.817660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64743198, states[0] = -94.574351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76743489, states[0] = -94.572793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89482169, states[0] = -94.823928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102817288, states[0] = -94.718729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117092669, states[0] = -0.414409, states[40]= 0.004933
Saving checkpoint... 
Iteration: 128905016, states[0] = -94.793061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142976022, states[0] = -94.819456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155990379, states[0] = -94.822587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170098832, states[0] = -4.588145, states[40]= 0.004160
Saving checkpoint... 
Iteration: 183014655, states[0] = 29.388101, states[40]= 0.011382
Saving checkpoint... 
Iteration: 196275421, states[0] = -94.646424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209252502, states[0] = -94.592371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221946286, states[0] = -94.809622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234942126, states[0] = -94.808075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247750927, states[0] = -94.587955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260947733, states[0] = -94.809944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272600024, states[0] = -5.464918, states[40]= 0.003954
Saving checkpoint... 
Iteration: 286341948, states[0] = -94.744383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299264759, states[0] = -94.622481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313545998, states[0] = 20.846605, states[40]= 0.003279
Saving checkpoint... 
Iteration: 326236935, states[0] = -94.547071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340227827, states[0] = -94.517512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352603528, states[0] = -8.215419, states[40]= 0.003269
Saving checkpoint... 
Iteration: 365506072, states[0] = 31.889856, states[40]= 0.173856
Saving checkpoint... 
Iteration: 377661296, states[0] = -60.398229, states[40]= 0.000022
Saving checkpoint... 
Iteration: 389380968, states[0] = -94.776628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403323830, states[0] = -94.723700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416844836, states[0] = -94.746827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430517279, states[0] = 29.088316, states[40]= 0.005778
Saving checkpoint... 
Iteration: 443246251, states[0] = -94.574332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455355498, states[0] = -94.756646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468575977, states[0] = 8.713882, states[40]= 0.005202
Saving checkpoint... 
Iteration: 480399202, states[0] = -94.787615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494655531, states[0] = -54.366630, states[40]= 0.000059
Saving checkpoint... 
Iteration: 508733045, states[0] = -94.534144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523010084, states[0] = 29.812706, states[40]= 0.046812
Saving checkpoint... 
Iteration: 537612742, states[0] = -16.069176, states[40]= 0.001767
Saving checkpoint... 
Iteration: 550935647, states[0] = -94.804536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564305612, states[0] = -94.698424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578721746, states[0] = -94.495675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590492424, states[0] = -94.821089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604414201, states[0] = -94.795040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617506972, states[0] = 30.987288, states[40]= 0.129682
Saving checkpoint... 
Iteration: 631003393, states[0] = 38.946162, states[40]= 0.383334
Saving checkpoint... 
Iteration: 645555325, states[0] = 17.429540, states[40]= 0.004004
Saving checkpoint... 
Iteration: 659009784, states[0] = 29.861048, states[40]= 0.051609
Saving checkpoint... 
Iteration: 670702420, states[0] = -94.409708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683120936, states[0] = -23.079813, states[40]= 0.001598
Saving checkpoint... 
Iteration: 696430922, states[0] = -94.802169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707788504, states[0] = -94.669851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721954757, states[0] = -94.810711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735804108, states[0] = -94.695583, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_673.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_673_1_r1147343819_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_673_1_r1147343819_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 109.330508
     * GNaL_b in INaL: 0.007131
     * Gto_b in Ito: 0.072762
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030590
     * GKs_b in IKs: 0.000099
     * GK1_b in IK1: 0.164942
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 72.327038
     * GKb_b in IKb: 0.003680
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.026722
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 735804108
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.695583 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 747440486, states[0] = -94.805716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761901500, states[0] = -94.787956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776277558, states[0] = -94.648705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790199108, states[0] = -94.371978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803820835, states[0] = -94.718615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816966754, states[0] = -94.813996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829520347, states[0] = 28.585421, states[40]= 0.003308
Saving checkpoint... 
Iteration: 843822796, states[0] = -94.720946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858357416, states[0] = -94.756975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871632618, states[0] = -32.930126, states[40]= 0.001073
Saving checkpoint... 
Iteration: 885384813, states[0] = -94.777530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899007547, states[0] = 30.601403, states[40]= 0.107403
Saving checkpoint... 
Iteration: 910443119, states[0] = -94.806133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923604883, states[0] = -9.326336, states[40]= 0.002994
Saving checkpoint... 
Iteration: 936566465, states[0] = 12.978205, states[40]= 0.004777
Saving checkpoint... 
Iteration: 949391523, states[0] = -94.781549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961995855, states[0] = -94.820574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975089448, states[0] = 1.608559, states[40]= 0.005154
Saving checkpoint... 
Iteration: 985520645, states[0] = 28.528451, states[40]= 0.003183
Saving checkpoint... 
Iteration: 995579212, states[0] = 7.140695, states[40]= 0.005277
Saving checkpoint... 
Iteration: 1008955303, states[0] = -94.809928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020471748, states[0] = -94.814690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033851317, states[0] = -94.750942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045128982, states[0] = -29.836777, states[40]= 0.001371
Saving checkpoint... 
Iteration: 1058128163, states[0] = -29.145282, states[40]= 0.001428
Saving checkpoint... 
Iteration: 1070581265, states[0] = 6.103734, states[40]= 0.005302
Saving checkpoint... 
Iteration: 1081936527, states[0] = -94.803106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094419622, states[0] = -94.795956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106800009, states[0] = -94.687971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119894268, states[0] = -94.782629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131968608, states[0] = -94.813464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145683847, states[0] = -90.867523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156139510, states[0] = -38.951775, states[40]= 0.000547
Saving checkpoint... 
Iteration: 1168531823, states[0] = 25.621412, states[40]= 0.002401
Saving checkpoint... 
Iteration: 1181793940, states[0] = -94.677757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193726006, states[0] = -94.508437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206524513, states[0] = 27.672968, states[40]= 0.002393
Saving checkpoint... 
Iteration: 1218586159, states[0] = 3.493569, states[40]= 0.005270
Saving checkpoint... 
Iteration: 1231572800, states[0] = 10.195474, states[40]= 0.005091
Saving checkpoint... 
Iteration: 1243908909, states[0] = -94.790275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256351994, states[0] = -94.750820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269217141, states[0] = -94.476705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280853005, states[0] = -94.751658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294018641, states[0] = 28.885510, states[40]= 0.004353
Saving checkpoint... 
Iteration: 1305292047, states[0] = -94.674099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318707103, states[0] = -94.435975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330405999, states[0] = -94.788479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343218878, states[0] = -94.482806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355947808, states[0] = -94.806296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368670490, states[0] = -71.407128, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1381228902, states[0] = -94.517601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394194416, states[0] = -94.227608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407002305, states[0] = 44.938301, states[40]= 0.420151
Saving checkpoint... 
Iteration: 1419640948, states[0] = -40.246810, states[40]= 0.000464
Saving checkpoint... 
Iteration: 1433286117, states[0] = -94.663064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442613480, states[0] = -16.707026, states[40]= 0.001707
Saving checkpoint... 
Iteration: 1454061073, states[0] = 15.195929, states[40]= 0.004430


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_673.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_673_1_r1147343819_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_673_1_r1147343819_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 109.330508
     * GNaL_b in INaL: 0.007131
     * Gto_b in Ito: 0.072762
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030590
     * GKs_b in IKs: 0.000099
     * GK1_b in IK1: 0.164942
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 72.327038
     * GKb_b in IKb: 0.003680
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.026722
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1454061073
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 15.195929 (After loading)
 - states[40]: 0.004430 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1466578688, states[0] = 7.401146, states[40]= 0.005268
Saving checkpoint... 
Iteration: 1477589772, states[0] = 1.417180, states[40]= 0.005138
Saving checkpoint... 
Iteration: 1490760321, states[0] = -94.607875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1503629803, states[0] = 20.455556, states[40]= 0.009059
Saving checkpoint... 
Iteration: 1516307921, states[0] = -94.858326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1527892659, states[0] = -43.017506, states[40]= 0.000438
Saving checkpoint... 
Iteration: 1540590885, states[0] = -94.698724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1552520206, states[0] = -94.681714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1565531779, states[0] = -94.590680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1578145783, states[0] = -34.212573, states[40]= 0.001019
Saving checkpoint... 
Iteration: 1591411118, states[0] = -94.503678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1602784917, states[0] = -94.252271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1616213426, states[0] = -93.374510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1627833487, states[0] = -94.256202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1640594924, states[0] = -94.397753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1653325910, states[0] = -94.402735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1665634735, states[0] = -94.392407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1678177873, states[0] = -94.392558, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.250538
 - CaMKt in component CaMK (millimolar): 0.001137
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.352977
 - nass in component intracellular_ions (millimolar): 6.353063
 - ki in component intracellular_ions (millimolar): 145.548093
 - kss in component intracellular_ions (millimolar): 145.548082
 - cansr in component intracellular_ions (millimolar): 1.570698
 - cajsr in component intracellular_ions (millimolar): 1.570670
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003864
 - hf in component INa (dimensionless): 0.868231
 - hs in component INa (dimensionless): 0.868231
 - j in component INa (dimensionless): 0.868232
 - hsp in component INa (dimensionless): 0.704054
 - jp in component INa (dimensionless): 0.868233
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.711661
 - hLp in component INaL (dimensionless): 0.518782
 - a in component Ito (dimensionless): 0.000651
 - iF in component Ito (dimensionless): 0.999854
 - iS in component Ito (dimensionless): 0.997672
 - ap in component Ito (dimensionless): 0.000332
 - iFp in component Ito (dimensionless): 0.999854
 - iSp in component Ito (dimensionless): 0.999220
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998769
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003039
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001921
 - xs1 in component IKs (dimensionless): 0.024076
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997503
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:43:00 (18452): called boinc_finish(0)

</stderr_txt>
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