𝕏

Task 55224194

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_973_1
Workunit 26225689
Created 28 Jun 2024, 6:09:21 UTC
Sent 29 Jun 2024, 5:52:22 UTC
Report deadline 2 Jul 2024, 8:45:10 UTC
Received 29 Jun 2024, 14:08:18 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213791
Run time 2 hours 12 min 34 sec
CPU time 2 hours 12 min 34 sec
Validate state Valid
Credit 47.90
Device peak FLOPS 3.69 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.63 MB
Peak swap size 6.22 MB
Peak disk usage 0.06 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_973.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_973_1_r1200184202_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_973_1_r1200184202_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.110820
     * GNaL_b in INaL: 0.004444
     * Gto_b in Ito: 0.091656
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032587
     * GKs_b in IKs: 0.002005
     * GK1_b in IK1: 0.036753
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 72.508387
     * GKb_b in IKb: 0.003686
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036362
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13328715, states[0] = -90.620729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25987268, states[0] = -90.707254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38986772, states[0] = -90.538022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48448425, states[0] = -90.420021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59843155, states[0] = -89.976341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71508825, states[0] = 26.809564, states[40]= 0.069883
Saving checkpoint... 
Iteration: 83845488, states[0] = -89.906829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95699638, states[0] = -79.984082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109112805, states[0] = -27.624989, states[40]= 0.000862
Saving checkpoint... 
Iteration: 120936604, states[0] = -90.200514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132455703, states[0] = -90.221936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145608842, states[0] = -23.437163, states[40]= 0.000983
Saving checkpoint... 
Iteration: 158207825, states[0] = -81.616863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170741635, states[0] = -86.536513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183386438, states[0] = -90.039953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196772677, states[0] = -88.519713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209478165, states[0] = -90.226614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221664982, states[0] = -68.475744, states[40]= 0.000003
Saving checkpoint... 
Iteration: 235210131, states[0] = -82.045228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247719501, states[0] = -83.706762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261002891, states[0] = 35.554498, states[40]= 0.464149
Saving checkpoint... 
Iteration: 271914428, states[0] = -90.122160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285075761, states[0] = 5.338432, states[40]= 0.003899
Saving checkpoint... 
Iteration: 296988295, states[0] = -90.231698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310346304, states[0] = -89.821953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322434769, states[0] = -90.165938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333214009, states[0] = -82.766176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344360798, states[0] = -89.914108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356676250, states[0] = -73.016551, states[40]= 0.000001
Saving checkpoint... 
Iteration: 369547587, states[0] = 18.123653, states[40]= 0.001994
Saving checkpoint... 
Iteration: 382242567, states[0] = -86.605538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393512266, states[0] = 27.114311, states[40]= 0.022003
Saving checkpoint... 
Iteration: 406220032, states[0] = -83.788271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418428475, states[0] = -90.152995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431006673, states[0] = 27.224544, states[40]= 0.143677
Saving checkpoint... 
Iteration: 442866842, states[0] = -89.946056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456258232, states[0] = -87.796462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466368425, states[0] = -89.953954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478258954, states[0] = -87.839568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488977345, states[0] = -90.221755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499687595, states[0] = -76.664409, states[40]= 0.000001
Saving checkpoint... 
Iteration: 511210217, states[0] = -82.056097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523668349, states[0] = -69.943471, states[40]= 0.000002
Saving checkpoint... 
Iteration: 536414992, states[0] = -90.121658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548756138, states[0] = -87.665087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561484501, states[0] = -90.227247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572531880, states[0] = 23.838355, states[40]= 0.001227
Saving checkpoint... 
Iteration: 585904074, states[0] = -90.091626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596688431, states[0] = -76.903532, states[40]= 0.000001
Saving checkpoint... 
Iteration: 608581554, states[0] = 1.883337, states[40]= 0.004017
Saving checkpoint... 
Iteration: 619490553, states[0] = -90.231243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632136449, states[0] = -50.080766, states[40]= 0.000065
Saving checkpoint... 
Iteration: 645476463, states[0] = -90.220110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658268126, states[0] = -88.316356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671671151, states[0] = -71.090780, states[40]= 0.000002
Saving checkpoint... 
Iteration: 684568546, states[0] = 9.094022, states[40]= 0.003505
Saving checkpoint... 
Iteration: 696641670, states[0] = -54.374359, states[40]= 0.000032
Saving checkpoint... 
Iteration: 709159478, states[0] = -65.799428, states[40]= 0.000004


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_973.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_973_1_r1200184202_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_973_1_r1200184202_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.110820
     * GNaL_b in INaL: 0.004444
     * Gto_b in Ito: 0.091656
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032587
     * GKs_b in IKs: 0.002005
     * GK1_b in IK1: 0.036753
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 72.508387
     * GKb_b in IKb: 0.003686
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036362
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 709159478
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -65.799428 (After loading)
 - states[40]: 0.000004 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 722450657, states[0] = -90.189775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734854213, states[0] = -89.872567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748216375, states[0] = -83.179287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760505480, states[0] = 28.143588, states[40]= 0.214039
Saving checkpoint... 
Iteration: 772812486, states[0] = -89.477598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784474843, states[0] = -90.217865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797313395, states[0] = -89.490117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809711916, states[0] = -82.377574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822321232, states[0] = -89.589213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835248835, states[0] = -87.141456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846669647, states[0] = -70.482154, states[40]= 0.000002
Saving checkpoint... 
Iteration: 859994790, states[0] = -90.232605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870659610, states[0] = -65.866594, states[40]= 0.000004
Saving checkpoint... 
Iteration: 883581150, states[0] = 2.141958, states[40]= 0.004017
Saving checkpoint... 
Iteration: 895732746, states[0] = -85.556418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906769016, states[0] = -88.354603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920206104, states[0] = -81.226032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931949973, states[0] = -90.187635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944991438, states[0] = -90.230046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957151144, states[0] = -61.042922, states[40]= 0.000010
Saving checkpoint... 
Iteration: 969830467, states[0] = -89.686079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982414776, states[0] = -90.118656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995481649, states[0] = -90.222633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008312633, states[0] = -89.478240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020686313, states[0] = -76.286503, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1033890406, states[0] = -90.044500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045035877, states[0] = 22.495852, states[40]= 0.001367
Saving checkpoint... 
Iteration: 1058413921, states[0] = -90.116067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069505490, states[0] = 28.131954, states[40]= 0.213324
Saving checkpoint... 
Iteration: 1082635033, states[0] = -48.844517, states[40]= 0.000079
Saving checkpoint... 
Iteration: 1095055052, states[0] = 15.119296, states[40]= 0.002516
Saving checkpoint... 
Iteration: 1107119997, states[0] = -34.629776, states[40]= 0.000518
Saving checkpoint... 
Iteration: 1119044972, states[0] = 19.140027, states[40]= 0.001830
Saving checkpoint... 
Iteration: 1131216073, states[0] = -83.124240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143628785, states[0] = -43.129672, states[40]= 0.000183
Saving checkpoint... 
Iteration: 1154405175, states[0] = -90.091705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166655228, states[0] = -63.489889, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1177155840, states[0] = -63.836553, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1189902529, states[0] = -90.083675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203432604, states[0] = -90.156884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215799934, states[0] = -89.269183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228565509, states[0] = 10.542641, states[40]= 0.003296
Saving checkpoint... 
Iteration: 1240854008, states[0] = -89.868401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254164168, states[0] = -68.090260, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1267175420, states[0] = -72.711626, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1279766320, states[0] = -88.227505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292623789, states[0] = -38.344124, states[40]= 0.000342
Saving checkpoint... 
Iteration: 1304533258, states[0] = 23.389103, states[40]= 0.001269
Saving checkpoint... 
Iteration: 1317821168, states[0] = -89.585527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329934603, states[0] = -90.159981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343304398, states[0] = -89.348779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354404637, states[0] = -90.089031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367245988, states[0] = -86.903577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380494596, states[0] = -90.229643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393069960, states[0] = 8.397676, states[40]= 0.003595
Saving checkpoint... 
Iteration: 1405707926, states[0] = -81.596476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417725966, states[0] = -84.670226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431164423, states[0] = -68.207111, states[40]= 0.000003


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_973.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_973_1_r1200184202_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_973_1_r1200184202_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.110820
     * GNaL_b in INaL: 0.004444
     * Gto_b in Ito: 0.091656
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032587
     * GKs_b in IKs: 0.002005
     * GK1_b in IK1: 0.036753
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 72.508387
     * GKb_b in IKb: 0.003686
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036362
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1431164423
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -68.207111 (After loading)
 - states[40]: 0.000003 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1444336533, states[0] = -89.738478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453635993, states[0] = -49.681810, states[40]= 0.000070
Saving checkpoint... 
Iteration: 1465610361, states[0] = -24.922237, states[40]= 0.000947
Saving checkpoint... 
Iteration: 1476827311, states[0] = -89.651735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489292530, states[0] = -89.112352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1501501710, states[0] = 33.741293, states[40]= 0.139782
Saving checkpoint... 
Iteration: 1512896511, states[0] = -73.687441, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1525154951, states[0] = -90.519064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537561176, states[0] = -89.659233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1550542305, states[0] = 20.568404, states[40]= 0.001139
Saving checkpoint... 
Iteration: 1562222110, states[0] = -77.672366, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1575436280, states[0] = -88.073357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1586299227, states[0] = -82.770441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1599542053, states[0] = 22.111656, states[40]= 0.000790
Saving checkpoint... 
Iteration: 1611950602, states[0] = -86.446995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1624658255, states[0] = -80.459514, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1637130359, states[0] = -76.777124, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1648462756, states[0] = -83.802215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1659672238, states[0] = -51.243534, states[40]= 0.000542
Saving checkpoint... 
Iteration: 1673051201, states[0] = -83.400538, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -49.117239
 - CaMKt in component CaMK (millimolar): 0.001208
 - cass in component intracellular_ions (millimolar): 0.000106
 - nai in component intracellular_ions (millimolar): 5.798879
 - nass in component intracellular_ions (millimolar): 5.799021
 - ki in component intracellular_ions (millimolar): 146.135716
 - kss in component intracellular_ions (millimolar): 146.135686
 - cansr in component intracellular_ions (millimolar): 1.382301
 - cajsr in component intracellular_ions (millimolar): 1.335279
 - cai in component intracellular_ions (millimolar): 0.000085
 - m in component INa (dimensionless): 0.272922
 - hf in component INa (dimensionless): 0.003950
 - hs in component INa (dimensionless): 0.003955
 - j in component INa (dimensionless): 0.003965
 - hsp in component INa (dimensionless): 0.001436
 - jp in component INa (dimensionless): 0.003972
 - mL in component INaL (dimensionless): 0.228942
 - hL in component INaL (dimensionless): 0.006242
 - hLp in component INaL (dimensionless): 0.005459
 - a in component Ito (dimensionless): 0.013514
 - iF in component Ito (dimensionless): 0.717232
 - iS in component Ito (dimensionless): 0.811505
 - ap in component Ito (dimensionless): 0.006928
 - iFp in component Ito (dimensionless): 0.717323
 - iSp in component Ito (dimensionless): 0.824366
 - d in component ICaL (dimensionless): 0.000022
 - ff in component ICaL (dimensionless): 0.999676
 - fs in component ICaL (dimensionless): 0.998646
 - fcaf in component ICaL (dimensionless): 0.999674
 - fcas in component ICaL (dimensionless): 0.999689
 - jca in component ICaL (dimensionless): 0.999685
 - ffp in component ICaL (dimensionless): 0.999681
 - fcafp in component ICaL (dimensionless): 0.999676
 - nca in component ICaL (dimensionless): 0.006475
 - xrf in component IKr (dimensionless): 0.002271
 - xrs in component IKr (dimensionless): 0.078410
 - xs1 in component IKs (dimensionless): 0.031988
 - xs2 in component IKs (dimensionless): 0.014301
 - xk1 in component IK1 (dimensionless): 0.999971
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000536
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000670
06:47:04 (9908): called boinc_finish(0)

</stderr_txt>
]]>


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