𝕏

Task 55224191

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_873_0
Workunit 26225688
Created 28 Jun 2024, 6:09:21 UTC
Sent 29 Jun 2024, 5:52:22 UTC
Report deadline 2 Jul 2024, 8:45:10 UTC
Received 29 Jun 2024, 14:08:18 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213791
Run time 2 hours 12 min 6 sec
CPU time 2 hours 12 min 6 sec
Validate state Valid
Credit 50.73
Device peak FLOPS 3.69 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.63 MB
Peak swap size 6.22 MB
Peak disk usage 0.06 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_873.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_873_0_r125998112_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_873_0_r125998112_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 118.383466
     * GNaL_b in INaL: 0.006789
     * Gto_b in Ito: 0.087340
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032947
     * GKs_b in IKs: 0.001843
     * GK1_b in IK1: 0.037658
     * Gncx_b in INaCa_i: 0.000975
     * Pnak_b in INaK: 75.230681
     * GKb_b in IKb: 0.003907
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034210
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12760223, states[0] = -90.348695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23957222, states[0] = -91.214902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37174079, states[0] = -73.263160, states[40]= 0.000001
Saving checkpoint... 
Iteration: 47321077, states[0] = -90.411032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58667836, states[0] = -69.848229, states[40]= 0.000002
Saving checkpoint... 
Iteration: 69749370, states[0] = -88.334287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81752022, states[0] = -88.433706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94125586, states[0] = -37.696997, states[40]= 0.000426
Saving checkpoint... 
Iteration: 107085907, states[0] = -0.316801, states[40]= 0.004431
Saving checkpoint... 
Iteration: 118253739, states[0] = -88.425866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129633433, states[0] = -44.869262, states[40]= 0.000164
Saving checkpoint... 
Iteration: 142966359, states[0] = -90.693943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155500133, states[0] = -74.228864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168819760, states[0] = -90.131083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182181100, states[0] = -74.688680, states[40]= 0.000001
Saving checkpoint... 
Iteration: 195515201, states[0] = 27.854481, states[40]= 0.009157
Saving checkpoint... 
Iteration: 207923273, states[0] = -90.615711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220710951, states[0] = -82.988639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232964864, states[0] = -90.676887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245294507, states[0] = -89.786606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258446347, states[0] = -90.653172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270097649, states[0] = -9.978235, states[40]= 0.002619
Saving checkpoint... 
Iteration: 283614898, states[0] = -27.143626, states[40]= 0.001028
Saving checkpoint... 
Iteration: 296611551, states[0] = -23.884038, states[40]= 0.001116
Saving checkpoint... 
Iteration: 309858840, states[0] = -90.399340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322284850, states[0] = -89.587578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332978464, states[0] = -90.687961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344346716, states[0] = -90.331558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356837227, states[0] = -90.268696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368725766, states[0] = -85.576737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380477085, states[0] = -90.686546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392576063, states[0] = 5.852361, states[40]= 0.004581
Saving checkpoint... 
Iteration: 404101580, states[0] = -13.881357, states[40]= 0.001863
Saving checkpoint... 
Iteration: 415165912, states[0] = -68.219095, states[40]= 0.000003
Saving checkpoint... 
Iteration: 426899602, states[0] = -90.554961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439516265, states[0] = 27.796393, states[40]= 0.006804
Saving checkpoint... 
Iteration: 452219498, states[0] = -84.588659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462797468, states[0] = -89.835323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475082709, states[0] = 1.934004, states[40]= 0.004592
Saving checkpoint... 
Iteration: 484897236, states[0] = -90.547867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496181669, states[0] = -74.873503, states[40]= 0.000001
Saving checkpoint... 
Iteration: 507124678, states[0] = -36.505579, states[40]= 0.000490
Saving checkpoint... 
Iteration: 519910855, states[0] = -90.584106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532097225, states[0] = -9.566357, states[40]= 0.002710
Saving checkpoint... 
Iteration: 545652959, states[0] = -60.717257, states[40]= 0.000012
Saving checkpoint... 
Iteration: 558236238, states[0] = -86.897071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570404317, states[0] = -90.567273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583056824, states[0] = 14.965827, states[40]= 0.003481
Saving checkpoint... 
Iteration: 596163929, states[0] = -67.210230, states[40]= 0.000003
Saving checkpoint... 
Iteration: 608516993, states[0] = 27.737448, states[40]= 0.005624
Saving checkpoint... 
Iteration: 619916411, states[0] = -90.596617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632721792, states[0] = -84.967041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645688648, states[0] = -77.219713, states[40]= 0.000001
Saving checkpoint... 
Iteration: 658751530, states[0] = -88.216600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672082234, states[0] = 2.234689, states[40]= 0.004603
Saving checkpoint... 
Iteration: 684742524, states[0] = -87.516011, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_873.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_873_0_r125998112_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_873_0_r125998112_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 118.383466
     * GNaL_b in INaL: 0.006789
     * Gto_b in Ito: 0.087340
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032947
     * GKs_b in IKs: 0.001843
     * GK1_b in IK1: 0.037658
     * Gncx_b in INaCa_i: 0.000975
     * Pnak_b in INaK: 75.230681
     * GKb_b in IKb: 0.003907
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034210
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 684742524
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -87.516011 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 696510651, states[0] = 27.830629, states[40]= 0.037945
Saving checkpoint... 
Iteration: 708092224, states[0] = -5.031091, states[40]= 0.003706
Saving checkpoint... 
Iteration: 721068061, states[0] = 9.953825, states[40]= 0.004245
Saving checkpoint... 
Iteration: 733370487, states[0] = -90.451528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746426906, states[0] = -90.617888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759683555, states[0] = -75.536937, states[40]= 0.000001
Saving checkpoint... 
Iteration: 769933645, states[0] = -90.630139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782092517, states[0] = -5.279729, states[40]= 0.003656
Saving checkpoint... 
Iteration: 793980528, states[0] = -90.687508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807119829, states[0] = -31.885993, states[40]= 0.000776
Saving checkpoint... 
Iteration: 817726869, states[0] = -85.731651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830843965, states[0] = -90.312067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843973746, states[0] = -90.681566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856707078, states[0] = -82.146739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868748503, states[0] = -88.002009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881508758, states[0] = 27.861989, states[40]= 0.070852
Saving checkpoint... 
Iteration: 891547374, states[0] = 18.751453, states[40]= 0.002770
Saving checkpoint... 
Iteration: 903701677, states[0] = -80.873135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916186006, states[0] = -76.365510, states[40]= 0.000001
Saving checkpoint... 
Iteration: 928783785, states[0] = -89.559014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941250873, states[0] = -88.170360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954203736, states[0] = -81.374046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966702690, states[0] = -81.121818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979537495, states[0] = 22.420347, states[40]= 0.002138
Saving checkpoint... 
Iteration: 990964090, states[0] = -90.671420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004160041, states[0] = -65.094594, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1016046217, states[0] = 19.196177, states[40]= 0.002687
Saving checkpoint... 
Iteration: 1029238534, states[0] = -87.134286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041259506, states[0] = -88.685580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054230656, states[0] = -86.237762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066651876, states[0] = -59.979460, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1079271613, states[0] = -89.203255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092188467, states[0] = -77.160358, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1104911460, states[0] = -90.582960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116371264, states[0] = -90.453104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127213918, states[0] = -83.570350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139207379, states[0] = -82.212101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151580400, states[0] = 3.362940, states[40]= 0.004627
Saving checkpoint... 
Iteration: 1164674994, states[0] = -72.312809, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1175312875, states[0] = -90.044215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186349920, states[0] = -90.346759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198323544, states[0] = -90.153705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211191449, states[0] = -78.077209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223593805, states[0] = -6.398592, states[40]= 0.003418
Saving checkpoint... 
Iteration: 1236378524, states[0] = -90.481728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248875972, states[0] = -90.471761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262268027, states[0] = -89.069302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274278649, states[0] = -89.423299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287692838, states[0] = -78.487503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298731012, states[0] = -86.281236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311745668, states[0] = -87.779777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323518110, states[0] = 27.620992, states[40]= 0.004305
Saving checkpoint... 
Iteration: 1336536909, states[0] = 22.627518, states[40]= 0.002107
Saving checkpoint... 
Iteration: 1349263566, states[0] = -88.880545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361308287, states[0] = -89.987914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374274476, states[0] = -89.297497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386419582, states[0] = -90.600156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399690805, states[0] = -77.882291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411879350, states[0] = -90.484072, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_873.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_873_0_r125998112_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_873_0_r125998112_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 118.383466
     * GNaL_b in INaL: 0.006789
     * Gto_b in Ito: 0.087340
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032947
     * GKs_b in IKs: 0.001843
     * GK1_b in IK1: 0.037658
     * Gncx_b in INaCa_i: 0.000975
     * Pnak_b in INaK: 75.230681
     * GKb_b in IKb: 0.003907
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034210
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1411879350
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -90.484072 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1425216093, states[0] = -83.979251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437202005, states[0] = -80.951224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450214999, states[0] = -83.774993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460943603, states[0] = -90.643190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472824334, states[0] = -90.159632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484871590, states[0] = -90.452817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497404709, states[0] = -90.564176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1510613730, states[0] = -48.162942, states[40]= 0.000160
Saving checkpoint... 
Iteration: 1523613627, states[0] = -88.208339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1536721336, states[0] = -90.230130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1548318818, states[0] = 11.084591, states[40]= 0.003481
Saving checkpoint... 
Iteration: 1561606827, states[0] = -89.138191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1573420625, states[0] = -88.701933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1586594293, states[0] = -88.001103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1599916404, states[0] = -87.359690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1612934214, states[0] = -86.394340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1624880659, states[0] = -84.039108, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1637346931, states[0] = -83.137742, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1649414027, states[0] = -82.971557, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1661762271, states[0] = -82.674016, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1674672054, states[0] = -80.019656, states[40]= 0.000001
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -66.845866
 - CaMKt in component CaMK (millimolar): 0.001072
 - cass in component intracellular_ions (millimolar): 0.000081
 - nai in component intracellular_ions (millimolar): 5.972694
 - nass in component intracellular_ions (millimolar): 5.972778
 - ki in component intracellular_ions (millimolar): 145.951743
 - kss in component intracellular_ions (millimolar): 145.951715
 - cansr in component intracellular_ions (millimolar): 1.456099
 - cajsr in component intracellular_ions (millimolar): 1.455816
 - cai in component intracellular_ions (millimolar): 0.000083
 - m in component INa (dimensionless): 0.058565
 - hf in component INa (dimensionless): 0.068614
 - hs in component INa (dimensionless): 0.070657
 - j in component INa (dimensionless): 0.077779
 - hsp in component INa (dimensionless): 0.028993
 - jp in component INa (dimensionless): 0.082863
 - mL in component INaL (dimensionless): 0.010103
 - hL in component INaL (dimensionless): 0.127689
 - hLp in component INaL (dimensionless): 0.103429
 - a in component Ito (dimensionless): 0.004112
 - iF in component Ito (dimensionless): 0.983494
 - iS in component Ito (dimensionless): 0.990126
 - ap in component Ito (dimensionless): 0.002098
 - iFp in component Ito (dimensionless): 0.983527
 - iSp in component Ito (dimensionless): 0.992571
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 0.999998
 - fs in component ICaL (dimensionless): 0.998884
 - fcaf in component ICaL (dimensionless): 0.999997
 - fcas in component ICaL (dimensionless): 0.999999
 - jca in component ICaL (dimensionless): 0.999998
 - ffp in component ICaL (dimensionless): 0.999998
 - fcafp in component ICaL (dimensionless): 0.999998
 - nca in component ICaL (dimensionless): 0.002288
 - xrf in component IKr (dimensionless): 0.000118
 - xrs in component IKr (dimensionless): 0.017757
 - xs1 in component IKs (dimensionless): 0.024559
 - xs2 in component IKs (dimensionless): 0.001672
 - xk1 in component IK1 (dimensionless): 0.999827
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000016
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000020
06:45:40 (15700): called boinc_finish(0)

</stderr_txt>
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