𝕏

Task 55224187

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_73_0
Workunit 26225686
Created 28 Jun 2024, 6:09:21 UTC
Sent 29 Jun 2024, 5:52:22 UTC
Report deadline 2 Jul 2024, 8:45:10 UTC
Received 29 Jun 2024, 13:44:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213791
Run time 2 hours 12 min 32 sec
CPU time 2 hours 12 min 32 sec
Validate state Valid
Credit 50.96
Device peak FLOPS 3.69 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.63 MB
Peak swap size 6.21 MB
Peak disk usage 0.06 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_73.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_73_0_r1379303920_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_73_0_r1379303920_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 114.758804
     * GNaL_b in INaL: 0.004852
     * Gto_b in Ito: 0.077550
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.031104
     * GKs_b in IKs: 0.002094
     * GK1_b in IK1: 0.044976
     * Gncx_b in INaCa_i: 0.000974
     * Pnak_b in INaK: 67.214209
     * GKb_b in IKb: 0.003878
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.047165
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11776364, states[0] = -91.053433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24986348, states[0] = -91.510328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36228484, states[0] = -88.149058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49145972, states[0] = -57.473931, states[40]= 0.000021
Saving checkpoint... 
Iteration: 58957662, states[0] = -91.350128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71556645, states[0] = 13.915385, states[40]= 0.003793
Saving checkpoint... 
Iteration: 84601516, states[0] = -16.771211, states[40]= 0.001486
Saving checkpoint... 
Iteration: 96398774, states[0] = -91.220362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109095456, states[0] = -10.560432, states[40]= 0.002525
Saving checkpoint... 
Iteration: 120457536, states[0] = -91.298588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133806180, states[0] = -90.807256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145692064, states[0] = -79.256101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156954749, states[0] = -91.288463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168984743, states[0] = -91.311531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181327793, states[0] = -90.946337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194350075, states[0] = -91.051962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205933151, states[0] = -91.259387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217542811, states[0] = 19.685613, states[40]= 0.002779
Saving checkpoint... 
Iteration: 229982939, states[0] = -91.307678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242322975, states[0] = -90.916318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255193962, states[0] = -79.846570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266687530, states[0] = -77.680686, states[40]= 0.000001
Saving checkpoint... 
Iteration: 279638162, states[0] = -50.899822, states[40]= 0.000064
Saving checkpoint... 
Iteration: 291571327, states[0] = 7.005173, states[40]= 0.004639
Saving checkpoint... 
Iteration: 304974091, states[0] = -91.300714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316086825, states[0] = -2.813083, states[40]= 0.004176
Saving checkpoint... 
Iteration: 328870029, states[0] = -91.121539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340782090, states[0] = -90.530765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353479579, states[0] = -91.304390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365860188, states[0] = -91.088337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378078444, states[0] = 2.956033, states[40]= 0.004721
Saving checkpoint... 
Iteration: 391134960, states[0] = -48.193882, states[40]= 0.000097
Saving checkpoint... 
Iteration: 404066878, states[0] = 9.281254, states[40]= 0.004454
Saving checkpoint... 
Iteration: 417009253, states[0] = 28.497662, states[40]= 0.059416
Saving checkpoint... 
Iteration: 428740018, states[0] = -88.920237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442007175, states[0] = 29.171944, states[40]= 0.117933
Saving checkpoint... 
Iteration: 454780170, states[0] = -90.500051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468039446, states[0] = 20.988843, states[40]= 0.002558
Saving checkpoint... 
Iteration: 479828363, states[0] = -90.946015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492823955, states[0] = -90.920693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504712596, states[0] = -84.926608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517034220, states[0] = 22.933573, states[40]= 0.002261
Saving checkpoint... 
Iteration: 529182395, states[0] = -75.805105, states[40]= 0.000001
Saving checkpoint... 
Iteration: 541024912, states[0] = 25.980399, states[40]= 0.002113
Saving checkpoint... 
Iteration: 553171287, states[0] = -71.257466, states[40]= 0.000002
Saving checkpoint... 
Iteration: 566542263, states[0] = 19.901442, states[40]= 0.002742
Saving checkpoint... 
Iteration: 578738145, states[0] = -88.759252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590422481, states[0] = -91.240798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603595719, states[0] = -10.727857, states[40]= 0.002489
Saving checkpoint... 
Iteration: 615743968, states[0] = -89.217405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628383386, states[0] = -91.158945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640892038, states[0] = -91.180668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654107902, states[0] = -22.983240, states[40]= 0.001128
Saving checkpoint... 
Iteration: 666721061, states[0] = -86.583998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678621470, states[0] = -35.976855, states[40]= 0.000507
Saving checkpoint... 
Iteration: 692010948, states[0] = 28.313626, states[40]= 0.034153
Saving checkpoint... 
Iteration: 704678202, states[0] = -74.173368, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_73.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_73_0_r1379303920_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_73_0_r1379303920_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 114.758804
     * GNaL_b in INaL: 0.004852
     * Gto_b in Ito: 0.077550
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.031104
     * GKs_b in IKs: 0.002094
     * GK1_b in IK1: 0.044976
     * Gncx_b in INaCa_i: 0.000974
     * Pnak_b in INaK: 67.214209
     * GKb_b in IKb: 0.003878
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.047165
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 704678202
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -74.173368 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 718014191, states[0] = 28.077735, states[40]= 0.012409
Saving checkpoint... 
Iteration: 730052143, states[0] = 15.919710, states[40]= 0.003468
Saving checkpoint... 
Iteration: 743549074, states[0] = 17.185493, states[40]= 0.003235
Saving checkpoint... 
Iteration: 755517873, states[0] = 27.603152, states[40]= 0.004726
Saving checkpoint... 
Iteration: 768929741, states[0] = -91.251136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780992741, states[0] = -91.310632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794187539, states[0] = -77.679823, states[40]= 0.000001
Saving checkpoint... 
Iteration: 806048450, states[0] = 17.439488, states[40]= 0.003188
Saving checkpoint... 
Iteration: 818469167, states[0] = -91.294691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831829573, states[0] = -90.951169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843960990, states[0] = -91.287492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856917321, states[0] = -91.231148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868279362, states[0] = -90.484885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880266056, states[0] = -90.201481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891852039, states[0] = -91.055418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903823090, states[0] = -90.913781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917183419, states[0] = -76.187109, states[40]= 0.000001
Saving checkpoint... 
Iteration: 927888385, states[0] = -91.170579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940151258, states[0] = -60.543945, states[40]= 0.000012
Saving checkpoint... 
Iteration: 951101716, states[0] = -16.779851, states[40]= 0.001486
Saving checkpoint... 
Iteration: 963351367, states[0] = -91.052437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974177664, states[0] = -73.955703, states[40]= 0.000001
Saving checkpoint... 
Iteration: 986936172, states[0] = -91.259173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999993363, states[0] = -91.310066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012482597, states[0] = -91.303678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025976782, states[0] = -91.299657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038197345, states[0] = -80.898854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051678071, states[0] = -74.119113, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1063109720, states[0] = -24.763449, states[40]= 0.001085
Saving checkpoint... 
Iteration: 1074527299, states[0] = 25.272543, states[40]= 0.002048
Saving checkpoint... 
Iteration: 1085715751, states[0] = -85.589888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097243084, states[0] = -89.152226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110655292, states[0] = -63.044911, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1121816219, states[0] = -90.869051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135498038, states[0] = -91.311885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146109061, states[0] = -24.119230, states[40]= 0.001101
Saving checkpoint... 
Iteration: 1158123938, states[0] = -38.270493, states[40]= 0.000387
Saving checkpoint... 
Iteration: 1169905342, states[0] = -91.207605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182133133, states[0] = -46.600344, states[40]= 0.000124
Saving checkpoint... 
Iteration: 1194367886, states[0] = -91.111063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205609346, states[0] = -24.397736, states[40]= 0.001094
Saving checkpoint... 
Iteration: 1218515539, states[0] = 27.937741, states[40]= 0.008440
Saving checkpoint... 
Iteration: 1230767885, states[0] = -90.247592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242283724, states[0] = -90.550915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253242335, states[0] = -89.096525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266343806, states[0] = -91.019270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278248520, states[0] = -89.499701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290844905, states[0] = -91.024009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304398471, states[0] = -91.192630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317300724, states[0] = -90.746287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330081356, states[0] = 1.106133, states[40]= 0.004637
Saving checkpoint... 
Iteration: 1342353508, states[0] = -91.059319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353614121, states[0] = -29.016708, states[40]= 0.000926
Saving checkpoint... 
Iteration: 1364328416, states[0] = -90.942571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377075346, states[0] = 4.793113, states[40]= 0.004726
Saving checkpoint... 
Iteration: 1390274598, states[0] = -90.396329, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_73.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_73_0_r1379303920_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_73_0_r1379303920_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 114.758804
     * GNaL_b in INaL: 0.004852
     * Gto_b in Ito: 0.077550
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.031104
     * GKs_b in IKs: 0.002094
     * GK1_b in IK1: 0.044976
     * Gncx_b in INaCa_i: 0.000974
     * Pnak_b in INaK: 67.214209
     * GKb_b in IKb: 0.003878
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.047165
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1390274598
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -90.396329 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1403763833, states[0] = -90.135934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416031838, states[0] = 23.777671, states[40]= 0.002153
Saving checkpoint... 
Iteration: 1429597912, states[0] = -12.913664, states[40]= 0.002052
Saving checkpoint... 
Iteration: 1441591819, states[0] = -7.021456, states[40]= 0.003325
Saving checkpoint... 
Iteration: 1454937302, states[0] = -91.258739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467695088, states[0] = -80.196249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480523657, states[0] = 26.326823, states[40]= 0.002220
Saving checkpoint... 
Iteration: 1493260578, states[0] = -90.032338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1505466666, states[0] = -60.724744, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1518576404, states[0] = -0.094161, states[40]= 0.004906
Saving checkpoint... 
Iteration: 1529960225, states[0] = -84.690765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1543002496, states[0] = 39.864893, states[40]= 0.498895
Saving checkpoint... 
Iteration: 1554741154, states[0] = -90.612040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1567226260, states[0] = -80.727405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1578876388, states[0] = -89.808979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1590748487, states[0] = -81.486392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1601728836, states[0] = -89.130514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1613660058, states[0] = -89.059707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1625319155, states[0] = -86.307048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636941498, states[0] = -87.688992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1648411530, states[0] = -88.107543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1661671788, states[0] = -87.533980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1673118736, states[0] = -88.211038, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -87.134598
 - CaMKt in component CaMK (millimolar): 0.001061
 - cass in component intracellular_ions (millimolar): 0.000084
 - nai in component intracellular_ions (millimolar): 6.307759
 - nass in component intracellular_ions (millimolar): 6.307840
 - ki in component intracellular_ions (millimolar): 145.603098
 - kss in component intracellular_ions (millimolar): 145.603087
 - cansr in component intracellular_ions (millimolar): 1.522254
 - cajsr in component intracellular_ions (millimolar): 1.522324
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.007914
 - hf in component INa (dimensionless): 0.671764
 - hs in component INa (dimensionless): 0.671773
 - j in component INa (dimensionless): 0.671821
 - hsp in component INa (dimensionless): 0.424965
 - jp in component INa (dimensionless): 0.671848
 - mL in component INaL (dimensionless): 0.000217
 - hL in component INaL (dimensionless): 0.488680
 - hLp in component INaL (dimensionless): 0.295629
 - a in component Ito (dimensionless): 0.001053
 - iF in component Ito (dimensionless): 0.999492
 - iS in component Ito (dimensionless): 0.995298
 - ap in component Ito (dimensionless): 0.000536
 - iFp in component Ito (dimensionless): 0.999492
 - iSp in component Ito (dimensionless): 0.997538
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998905
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002683
 - xrf in component IKr (dimensionless): 0.000009
 - xrs in component IKr (dimensionless): 0.007957
 - xs1 in component IKs (dimensionless): 0.023056
 - xs2 in component IKs (dimensionless): 0.000209
 - xk1 in component IK1 (dimensionless): 0.998765
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
06:06:12 (1236): called boinc_finish(0)

</stderr_txt>
]]>


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