𝕏

Task 55222049

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_4000-conf_370_0
Workunit 26224618
Created 28 Jun 2024, 6:08:27 UTC
Sent 29 Jun 2024, 5:32:03 UTC
Report deadline 2 Jul 2024, 5:32:03 UTC
Received 1 Jul 2024, 23:06:31 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241013
Run time 1 hours 35 min 35 sec
CPU time 1 hours 35 min 3 sec
Validate state Valid
Credit 44.17
Device peak FLOPS 5.56 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 3.00 MB
Peak swap size 4.31 MB
Peak disk usage 1.25 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_4000-conf_370.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_4000-conf_370_0_r1504754793_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_4000-conf_370_0_r1504754793_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 92.398091
     * GNaL_b in INaL: 0.005890
     * Gto_b in Ito: 0.080244
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032972
     * GKs_b in IKs: 0.001907
     * GK1_b in IK1: 0.147961
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.122158
     * GKb_b in IKb: 0.003813
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.039123
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11981423, states[0] = -86.622910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23914705, states[0] = -86.533383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35526589, states[0] = -86.479551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47293928, states[0] = -86.443310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59730382, states[0] = -86.407903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71848093, states[0] = -86.386523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83916129, states[0] = -86.371372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96149769, states[0] = -44.819369, states[40]= 0.000060
Saving checkpoint... 
Iteration: 108263799, states[0] = -86.198565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120496426, states[0] = -86.350329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132682574, states[0] = -86.361630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144663065, states[0] = -86.358118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156655032, states[0] = -86.355578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168800652, states[0] = -86.354487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180861429, states[0] = -86.352185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192851838, states[0] = -86.351377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204989488, states[0] = -86.347539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217159048, states[0] = -86.342851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229022600, states[0] = -86.345731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241066260, states[0] = -86.344330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253050428, states[0] = -86.344478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265274634, states[0] = -86.339137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277045926, states[0] = -86.344266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289339527, states[0] = -86.337605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301555893, states[0] = -86.333951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313399590, states[0] = -86.336364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325711986, states[0] = -86.331865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337705234, states[0] = -86.331906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349915729, states[0] = -86.329805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362052952, states[0] = 15.333798, states[40]= 0.004186
Saving checkpoint... 
Iteration: 373774801, states[0] = -86.331085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386097440, states[0] = -1.493090, states[40]= 0.003485
Saving checkpoint... 
Iteration: 398237715, states[0] = -86.133244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410368734, states[0] = -86.287018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422250734, states[0] = -86.155176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434172350, states[0] = -64.657294, states[40]= 0.000002
Saving checkpoint... 
Iteration: 446387089, states[0] = -86.297576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458365967, states[0] = -86.285238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470379799, states[0] = -86.293583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482586634, states[0] = -86.345064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494524668, states[0] = -86.338466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506719147, states[0] = -86.349512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518664899, states[0] = -86.348746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530879502, states[0] = -86.347744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542902311, states[0] = -86.347252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555107113, states[0] = -86.342293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566867425, states[0] = -86.347982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579036891, states[0] = -86.344010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591232172, states[0] = -86.339412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603204906, states[0] = -86.340008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615072831, states[0] = -86.343115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627257490, states[0] = -86.338865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639012870, states[0] = -86.344593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651188382, states[0] = -86.340369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663453752, states[0] = -86.335195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675301818, states[0] = -86.337946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687533727, states[0] = -86.333954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699450038, states[0] = -86.335248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711830876, states[0] = -86.330417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724016660, states[0] = 22.321938, states[40]= 0.011201
Saving checkpoint... 
Iteration: 736010080, states[0] = 22.280730, states[40]= 0.042822
Saving checkpoint... 
Iteration: 748222989, states[0] = -86.108231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760366149, states[0] = -86.285289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772184232, states[0] = -77.971834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784441187, states[0] = -86.319949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796410507, states[0] = -86.308610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808616413, states[0] = -86.346868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820766198, states[0] = -86.349382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832766480, states[0] = -86.349378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845000812, states[0] = -86.344850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857045686, states[0] = -86.343736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869217095, states[0] = -86.339685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881420472, states[0] = -86.335708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893352562, states[0] = -86.336921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905262320, states[0] = -86.338708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917477780, states[0] = -86.334758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929182881, states[0] = -86.340439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941055001, states[0] = -86.343489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953176866, states[0] = -86.340571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965201215, states[0] = -86.340018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977401344, states[0] = -86.336020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989380968, states[0] = -86.336380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001554556, states[0] = -86.333591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013820045, states[0] = -86.330461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025489340, states[0] = -86.334555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037654818, states[0] = -86.332260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049800868, states[0] = -86.330642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061719497, states[0] = -86.331498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073924900, states[0] = -86.329506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086039000, states[0] = 18.968480, states[40]= 0.004292
Saving checkpoint... 
Iteration: 1097554515, states[0] = -86.333572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109762069, states[0] = -86.331026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121784197, states[0] = -86.330795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134059477, states[0] = 13.455552, states[40]= 0.004217
Saving checkpoint... 
Iteration: 1146230309, states[0] = -86.120690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158126797, states[0] = -23.853622, states[40]= 0.000764
Saving checkpoint... 
Iteration: 1170250750, states[0] = -86.155039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182129624, states[0] = -26.251129, states[40]= 0.000670
Saving checkpoint... 
Iteration: 1194151953, states[0] = -45.528012, states[40]= 0.000053
Saving checkpoint... 
Iteration: 1206354117, states[0] = -86.277016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218368716, states[0] = -86.286827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230526935, states[0] = -86.338639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242776190, states[0] = -86.349221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254664722, states[0] = -86.348594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266868987, states[0] = -86.347811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279033280, states[0] = -86.343959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290720204, states[0] = -86.349358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302873402, states[0] = -86.347715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314978099, states[0] = -86.345315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326935505, states[0] = -86.346337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338835743, states[0] = -86.348415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350724066, states[0] = -86.349361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362675898, states[0] = -86.348823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374819831, states[0] = -86.348665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386913566, states[0] = -86.346831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398973724, states[0] = -86.345405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411159808, states[0] = -86.340873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423146837, states[0] = -86.341173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435275375, states[0] = -86.338331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447461445, states[0] = -86.334913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459445731, states[0] = -86.335167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471714205, states[0] = -86.331475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483920984, states[0] = -86.329457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495824265, states[0] = -86.330324, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.204795
 - CaMKt in component CaMK (millimolar): 0.000889
 - cass in component intracellular_ions (millimolar): 0.000069
 - nai in component intracellular_ions (millimolar): 6.058699
 - nass in component intracellular_ions (millimolar): 6.058744
 - ki in component intracellular_ions (millimolar): 145.937053
 - kss in component intracellular_ions (millimolar): 145.937042
 - cansr in component intracellular_ions (millimolar): 1.250460
 - cajsr in component intracellular_ions (millimolar): 1.250574
 - cai in component intracellular_ions (millimolar): 0.000071
 - m in component INa (dimensionless): 0.008689
 - hf in component INa (dimensionless): 0.637238
 - hs in component INa (dimensionless): 0.637239
 - j in component INa (dimensionless): 0.637242
 - hsp in component INa (dimensionless): 0.388095
 - jp in component INa (dimensionless): 0.637244
 - mL in component INaL (dimensionless): 0.000259
 - hL in component INaL (dimensionless): 0.457359
 - hLp in component INaL (dimensionless): 0.268906
 - a in component Ito (dimensionless): 0.001121
 - iF in component Ito (dimensionless): 0.999403
 - iS in component Ito (dimensionless): 0.985363
 - ap in component Ito (dimensionless): 0.000571
 - iFp in component Ito (dimensionless): 0.999403
 - iSp in component Ito (dimensionless): 0.991470
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.997496
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001270
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.020617
 - xs1 in component IKs (dimensionless): 0.036989
 - xs2 in component IKs (dimensionless): 0.000232
 - xk1 in component IK1 (dimensionless): 0.997171
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:11:31 (162295): called boinc_finish(0)

</stderr_txt>
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