𝕏

Task 55219530

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-TESZT_Block_Kr_70-conf_567_1
Workunit 26223360
Created 28 Jun 2024, 6:07:19 UTC
Sent 29 Jun 2024, 5:09:28 UTC
Report deadline 2 Jul 2024, 5:09:28 UTC
Received 29 Jun 2024, 12:58:32 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 219692
Run time 2 hours 4 min 29 sec
CPU time 2 hours 4 min 29 sec
Validate state Valid
Credit 43.56
Device peak FLOPS 2.80 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.68 MB
Peak swap size 6.23 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-TESZT_Block_Kr_70-conf_567.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-TESZT_Block_Kr_70-conf_567_1_r1784071382_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-TESZT_Block_Kr_70-conf_567_1_r1784071382_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 91.888387
     * GNaL_b in INaL: 0.006461
     * Gto_b in Ito: 0.090549
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.010003
     * GKs_b in IKs: 0.001985
     * GK1_b in IK1: 0.157706
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 75.254724
     * GKb_b in IKb: 0.003725
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025274
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11641215, states[0] = -13.846541, states[40]= 0.002265
Saving checkpoint... 
Iteration: 22982590, states[0] = -94.847446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34713889, states[0] = -37.761401, states[40]= 0.001501
Saving checkpoint... 
Iteration: 46424306, states[0] = -94.758658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58175145, states[0] = -22.825391, states[40]= 0.005176
Saving checkpoint... 
Iteration: 69964054, states[0] = -94.756810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81588424, states[0] = 11.706292, states[40]= 0.004912
Saving checkpoint... 
Iteration: 93295964, states[0] = -81.847525, states[40]= 0.000001
Saving checkpoint... 
Iteration: 105067829, states[0] = 18.551085, states[40]= 0.004131
Saving checkpoint... 
Iteration: 116905860, states[0] = -94.697393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128723359, states[0] = -36.821499, states[40]= 0.001612
Saving checkpoint... 
Iteration: 140497237, states[0] = -94.746493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152044025, states[0] = 25.523849, states[40]= 0.002741
Saving checkpoint... 
Iteration: 164079205, states[0] = 15.109289, states[40]= 0.004654
Saving checkpoint... 
Iteration: 175775539, states[0] = -59.671089, states[40]= 0.000045
Saving checkpoint... 
Iteration: 187821867, states[0] = -94.514308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199859610, states[0] = -94.636076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211776880, states[0] = -60.298455, states[40]= 0.000040
Saving checkpoint... 
Iteration: 223860409, states[0] = -94.636631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235740042, states[0] = -42.771095, states[40]= 0.000712
Saving checkpoint... 
Iteration: 247144558, states[0] = -9.625863, states[40]= 0.002899
Saving checkpoint... 
Iteration: 258713316, states[0] = -32.928978, states[40]= 0.002565
Saving checkpoint... 
Iteration: 270373387, states[0] = -94.653494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282185117, states[0] = -24.265001, states[40]= 0.005052
Saving checkpoint... 
Iteration: 293710009, states[0] = -31.830552, states[40]= 0.002896
Saving checkpoint... 
Iteration: 305415944, states[0] = -94.696546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316962975, states[0] = -94.726727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328612155, states[0] = 3.677211, states[40]= 0.004987
Saving checkpoint... 
Iteration: 340349876, states[0] = -94.619765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352007693, states[0] = 29.955601, states[40]= 0.095693
Saving checkpoint... 
Iteration: 363633402, states[0] = -4.727515, states[40]= 0.003878
Saving checkpoint... 
Iteration: 375606184, states[0] = 5.864400, states[40]= 0.005055
Saving checkpoint... 
Iteration: 387488283, states[0] = -94.737684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399222570, states[0] = -36.099793, states[40]= 0.001753
Saving checkpoint... 
Iteration: 411041249, states[0] = 26.334730, states[40]= 0.002626
Saving checkpoint... 
Iteration: 422980777, states[0] = -94.734552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434594730, states[0] = 9.926132, states[40]= 0.005011
Saving checkpoint... 
Iteration: 446520823, states[0] = 30.678041, states[40]= 0.003162
Saving checkpoint... 
Iteration: 458294583, states[0] = -74.744009, states[40]= 0.000003
Saving checkpoint... 
Iteration: 470135051, states[0] = -5.432732, states[40]= 0.003730
Saving checkpoint... 
Iteration: 481871463, states[0] = -94.650268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493511565, states[0] = 30.304793, states[40]= 0.027683
Saving checkpoint... 
Iteration: 505481260, states[0] = -94.734524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516938336, states[0] = -94.712082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528374615, states[0] = -94.654115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539875933, states[0] = -94.655707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551550181, states[0] = 23.848462, states[40]= 0.003119
Saving checkpoint... 
Iteration: 563544086, states[0] = 25.553197, states[40]= 0.002770
Saving checkpoint... 
Iteration: 575383431, states[0] = -94.664443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587099430, states[0] = 8.279476, states[40]= 0.005053
Saving checkpoint... 
Iteration: 598795676, states[0] = -76.079415, states[40]= 0.000003
Saving checkpoint... 
Iteration: 610630872, states[0] = -3.658695, states[40]= 0.004093
Saving checkpoint... 
Iteration: 622548938, states[0] = 24.198111, states[40]= 0.003044
Saving checkpoint... 
Iteration: 634436151, states[0] = -94.710337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646370446, states[0] = -94.648504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658533913, states[0] = 28.265632, states[40]= 0.002335
Saving checkpoint... 
Iteration: 670508475, states[0] = 29.917691, states[40]= 0.074279
Saving checkpoint... 
Iteration: 682387533, states[0] = -94.668699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694011445, states[0] = 30.285703, states[40]= 0.028740
Saving checkpoint... 
Iteration: 705800408, states[0] = -82.599979, states[40]= 0.000001
Saving checkpoint... 
Iteration: 717743905, states[0] = -44.317980, states[40]= 0.000567
Saving checkpoint... 
Iteration: 729778555, states[0] = -61.199120, states[40]= 0.000034
Saving checkpoint... 
Iteration: 741994752, states[0] = -94.739136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753996501, states[0] = -94.739734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766013212, states[0] = 30.546985, states[40]= 0.016752
Saving checkpoint... 
Iteration: 777980875, states[0] = -94.733617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789980329, states[0] = -94.733355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801970619, states[0] = -94.729027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813960778, states[0] = -94.724190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825681137, states[0] = -23.089315, states[40]= 0.005168
Saving checkpoint... 
Iteration: 837787915, states[0] = -67.987181, states[40]= 0.000011
Saving checkpoint... 
Iteration: 849634160, states[0] = -5.049711, states[40]= 0.003811
Saving checkpoint... 
Iteration: 861562466, states[0] = 20.326455, states[40]= 0.003873
Saving checkpoint... 
Iteration: 873308930, states[0] = -92.205035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885097918, states[0] = 8.812534, states[40]= 0.005043
Saving checkpoint... 
Iteration: 897161901, states[0] = -16.877029, states[40]= 0.003412
Saving checkpoint... 
Iteration: 909141013, states[0] = -8.038161, states[40]= 0.003185
Saving checkpoint... 
Iteration: 921126903, states[0] = -2.022793, states[40]= 0.004388
Saving checkpoint... 
Iteration: 933154409, states[0] = -13.902068, states[40]= 0.002668
Saving checkpoint... 
Iteration: 945118246, states[0] = 1.385924, states[40]= 0.004828
Saving checkpoint... 
Iteration: 956850083, states[0] = -94.618361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968833141, states[0] = -94.586840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980867302, states[0] = -94.643446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992693758, states[0] = -26.793960, states[40]= 0.004501
Saving checkpoint... 
Iteration: 1004764566, states[0] = -53.593805, states[40]= 0.000128
Saving checkpoint... 
Iteration: 1016790539, states[0] = -70.383639, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1028612471, states[0] = 3.561866, states[40]= 0.004981
Saving checkpoint... 
Iteration: 1040267898, states[0] = -55.254698, states[40]= 0.000096
Saving checkpoint... 
Iteration: 1052036721, states[0] = 27.549364, states[40]= 0.002431
Saving checkpoint... 
Iteration: 1064001136, states[0] = 46.828389, states[40]= 0.165543
Saving checkpoint... 
Iteration: 1075992355, states[0] = -94.737339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087824311, states[0] = -94.540568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099498548, states[0] = -94.739513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111189377, states[0] = -25.503955, states[40]= 0.004825
Saving checkpoint... 
Iteration: 1122950880, states[0] = -94.718004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134853881, states[0] = -94.623799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146946012, states[0] = -94.715110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158801663, states[0] = -84.413398, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1170729297, states[0] = -38.550920, states[40]= 0.001276
Saving checkpoint... 
Iteration: 1182827499, states[0] = -94.565508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194747884, states[0] = -45.996265, states[40]= 0.000440
Saving checkpoint... 
Iteration: 1206532247, states[0] = 28.671346, states[40]= 0.002291
Saving checkpoint... 
Iteration: 1218499341, states[0] = -94.739463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229858826, states[0] = -94.630924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241515668, states[0] = 30.775892, states[40]= 0.008446
Saving checkpoint... 
Iteration: 1253246487, states[0] = -45.401196, states[40]= 0.000482
Saving checkpoint... 
Iteration: 1265136720, states[0] = -6.153435, states[40]= 0.003576
Saving checkpoint... 
Iteration: 1277114241, states[0] = 2.902118, states[40]= 0.004944
Saving checkpoint... 
Iteration: 1289054924, states[0] = 22.506195, states[40]= 0.003413
Saving checkpoint... 
Iteration: 1300740514, states[0] = -42.922540, states[40]= 0.000696
Saving checkpoint... 
Iteration: 1312373382, states[0] = -94.650419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324253057, states[0] = -48.249886, states[40]= 0.000309
Saving checkpoint... 
Iteration: 1336019430, states[0] = 30.774582, states[40]= 0.003829
Saving checkpoint... 
Iteration: 1348002247, states[0] = 42.603545, states[40]= 0.367609
Saving checkpoint... 
Iteration: 1360097917, states[0] = 8.813340, states[40]= 0.005043
Saving checkpoint... 
Iteration: 1372125473, states[0] = -1.444782, states[40]= 0.004480
Saving checkpoint... 
Iteration: 1384136335, states[0] = -5.986111, states[40]= 0.003612
Saving checkpoint... 
Iteration: 1396097495, states[0] = 8.961567, states[40]= 0.005040
Saving checkpoint... 
Iteration: 1407595015, states[0] = 9.828023, states[40]= 0.005015
Saving checkpoint... 
Iteration: 1419396008, states[0] = -94.675486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431280305, states[0] = -62.311891, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1443204546, states[0] = -30.076370, states[40]= 0.003462
Saving checkpoint... 
Iteration: 1455161033, states[0] = -16.550612, states[40]= 0.003285
Saving checkpoint... 
Iteration: 1467150521, states[0] = -12.238408, states[40]= 0.002624
Saving checkpoint... 
Iteration: 1479013832, states[0] = 30.622251, states[40]= 0.013970
Saving checkpoint... 
Iteration: 1491093733, states[0] = 10.272973, states[40]= 0.004999
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.614798
 - CaMKt in component CaMK (millimolar): 0.015555
 - cass in component intracellular_ions (millimolar): 0.000084
 - nai in component intracellular_ions (millimolar): 6.165540
 - nass in component intracellular_ions (millimolar): 6.165621
 - ki in component intracellular_ions (millimolar): 145.744610
 - kss in component intracellular_ions (millimolar): 145.744601
 - cansr in component intracellular_ions (millimolar): 1.575952
 - cajsr in component intracellular_ions (millimolar): 1.506525
 - cai in component intracellular_ions (millimolar): 0.000086
 - m in component INa (dimensionless): 0.003725
 - hf in component INa (dimensionless): 0.874930
 - hs in component INa (dimensionless): 0.874916
 - j in component INa (dimensionless): 0.874824
 - hsp in component INa (dimensionless): 0.716289
 - jp in component INa (dimensionless): 0.874697
 - mL in component INaL (dimensionless): 0.000052
 - hL in component INaL (dimensionless): 0.627414
 - hLp in component INaL (dimensionless): 0.315335
 - a in component Ito (dimensionless): 0.000636
 - iF in component Ito (dimensionless): 0.999863
 - iS in component Ito (dimensionless): 0.463906
 - ap in component Ito (dimensionless): 0.000324
 - iFp in component Ito (dimensionless): 0.999863
 - iSp in component Ito (dimensionless): 0.515594
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.845482
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.998972
 - jca in component ICaL (dimensionless): 0.999821
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002668
 - xrf in component IKr (dimensionless): 0.000007
 - xrs in component IKr (dimensionless): 0.529147
 - xs1 in component IKs (dimensionless): 0.371030
 - xs2 in component IKs (dimensionless): 0.000091
 - xk1 in component IK1 (dimensionless): 0.997412
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:58:00 (36744): called boinc_finish(0)

</stderr_txt>
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