𝕏

Task 55214078

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pueyo_APDR-conf_861_1
Workunit 26220637
Created 28 Jun 2024, 6:04:56 UTC
Sent 29 Jun 2024, 4:15:20 UTC
Report deadline 2 Jul 2024, 13:51:20 UTC
Received 2 Jul 2024, 15:10:11 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236758
Run time 2 hours 38 min 1 sec
CPU time 2 hours 34 min 52 sec
Validate state Valid
Credit 60.53
Device peak FLOPS 3.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 6.96 MB
Peak swap size 1.53 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pueyo_APDR-conf_861.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pueyo_APDR-conf_861_1_r477669012_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pueyo_APDR-conf_861_1_r477669012_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 101.056598
     * GNaL_b in INaL: 0.005823
     * Gto_b in Ito: 0.085541
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031055
     * GKs_b in IKs: 0.001803
     * GK1_b in IK1: 0.148691
     * Gncx_b in INaCa_i: 0.000978
     * Pnak_b in INaK: 70.274706
     * GKb_b in IKb: 0.003847
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.050726
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14288656, states[0] = -94.802045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28677920, states[0] = -94.497990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43098567, states[0] = -18.008532, states[40]= 0.001109
Saving checkpoint... 
Iteration: 57505354, states[0] = 27.022069, states[40]= 0.138852
Saving checkpoint... 
Iteration: 71929712, states[0] = -94.796794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86312915, states[0] = -94.742310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99578237, states[0] = -0.977406, states[40]= 0.004034
Saving checkpoint... 
Iteration: 113907678, states[0] = -94.781482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128270845, states[0] = -94.698258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142483002, states[0] = -94.794486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156823129, states[0] = -94.741501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171185269, states[0] = -94.525007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185549837, states[0] = 11.832818, states[40]= 0.004904
Saving checkpoint... 
Iteration: 199913163, states[0] = -94.779404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214257276, states[0] = -94.679765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228649993, states[0] = -67.168581, states[40]= 0.000001
Saving checkpoint... 
Iteration: 242849640, states[0] = -94.755555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257243494, states[0] = -94.660804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271602056, states[0] = -19.756417, states[40]= 0.000970
Saving checkpoint... 
Iteration: 286004696, states[0] = 28.781375, states[40]= 0.147136
Saving checkpoint... 
Iteration: 299162402, states[0] = -84.616734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313450097, states[0] = -94.787426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327819571, states[0] = -94.737977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342200146, states[0] = -94.583753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356518097, states[0] = 21.537212, states[40]= 0.011784
Saving checkpoint... 
Iteration: 370846537, states[0] = -94.753825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385176357, states[0] = -94.166331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399000664, states[0] = 40.272690, states[40]= 0.004623
Saving checkpoint... 
Iteration: 413384177, states[0] = -94.769972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427699915, states[0] = -94.583201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442027269, states[0] = 19.488380, states[40]= 0.006504
Saving checkpoint... 
Iteration: 456348370, states[0] = -94.754704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470642141, states[0] = -58.458036, states[40]= 0.000006
Saving checkpoint... 
Iteration: 485077201, states[0] = -0.237993, states[40]= 0.004133
Saving checkpoint... 
Iteration: 499084752, states[0] = -4.972437, states[40]= 0.003328
Saving checkpoint... 
Iteration: 513425607, states[0] = -94.782075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527809922, states[0] = -94.731041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542248447, states[0] = -94.667628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556722155, states[0] = -94.626076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571049431, states[0] = 11.992440, states[40]= 0.004910
Saving checkpoint... 
Iteration: 585449362, states[0] = -94.787111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599834368, states[0] = -94.747042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614075981, states[0] = 0.433425, states[40]= 0.004219
Saving checkpoint... 
Iteration: 628375780, states[0] = -94.766726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642756851, states[0] = -94.678762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657122871, states[0] = -39.029113, states[40]= 0.000144
Saving checkpoint... 
Iteration: 671393981, states[0] = -94.773143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685725372, states[0] = -94.631627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699046485, states[0] = 13.093356, states[40]= 0.004967
Saving checkpoint... 
Iteration: 713379232, states[0] = -94.767985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727757172, states[0] = -94.679119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742044070, states[0] = 13.981776, states[40]= 0.005029
Saving checkpoint... 
Iteration: 756324484, states[0] = -94.740928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770613802, states[0] = -30.560335, states[40]= 0.000435
Saving checkpoint... 
Iteration: 784933610, states[0] = -94.783751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799260917, states[0] = -94.683749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813608714, states[0] = -25.876731, states[40]= 0.000659
Saving checkpoint... 
Iteration: 827935621, states[0] = -94.784166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842265184, states[0] = -94.688834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856625136, states[0] = -41.201891, states[40]= 0.000105
Saving checkpoint... 
Iteration: 870959448, states[0] = -94.788766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885360914, states[0] = -94.760395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898325319, states[0] = -94.741373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912648915, states[0] = -65.892967, states[40]= 0.000002
Saving checkpoint... 
Iteration: 926993533, states[0] = -94.793738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941273505, states[0] = -94.698118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955615455, states[0] = -32.087635, states[40]= 0.000366
Saving checkpoint... 
Iteration: 969942804, states[0] = -94.785587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984278927, states[0] = -94.703763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998653112, states[0] = -71.024941, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1013045393, states[0] = 13.496702, states[40]= 0.004993
Saving checkpoint... 
Iteration: 1027340080, states[0] = -94.749997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041692098, states[0] = -94.563089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056054796, states[0] = 9.933510, states[40]= 0.004836
Saving checkpoint... 
Iteration: 1070318257, states[0] = -94.736627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084540276, states[0] = 15.346372, states[40]= 0.005169
Saving checkpoint... 
Iteration: 1098449315, states[0] = -94.786788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112769163, states[0] = -94.693237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127162984, states[0] = -85.467292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141574256, states[0] = 1.348100, states[40]= 0.004325
Saving checkpoint... 
Iteration: 1155945318, states[0] = -94.785977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170268250, states[0] = -94.692170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184662665, states[0] = -85.002110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198947578, states[0] = -94.786393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213304337, states[0] = -94.726366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227700786, states[0] = -94.584563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242024571, states[0] = 20.185413, states[40]= 0.007210
Saving checkpoint... 
Iteration: 1256121169, states[0] = -37.416243, states[40]= 0.000182
Saving checkpoint... 
Iteration: 1270491208, states[0] = -94.793237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284873187, states[0] = -94.765311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298286574, states[0] = -94.711049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312641407, states[0] = -57.684769, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1326965826, states[0] = -94.789555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341311963, states[0] = -94.732038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355538845, states[0] = 15.848010, states[40]= 0.005239
Saving checkpoint... 
Iteration: 1369888276, states[0] = -94.770817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384258080, states[0] = -94.679865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398667888, states[0] = -91.106100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413062349, states[0] = 6.871601, states[40]= 0.004727
Saving checkpoint... 
Iteration: 1427433517, states[0] = -94.783338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441748028, states[0] = -94.666491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456098581, states[0] = -16.553258, states[40]= 0.001248
Saving checkpoint... 
Iteration: 1470381664, states[0] = -94.768419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484671024, states[0] = -92.957182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498119086, states[0] = -35.461401, states[40]= 0.000239
Saving checkpoint... 
Iteration: 1512445132, states[0] = -90.090821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1526708532, states[0] = 24.649946, states[40]= 0.070856
Saving checkpoint... 
Iteration: 1540969376, states[0] = -94.892632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1555261422, states[0] = 1.451899, states[40]= 0.004909
Saving checkpoint... 
Iteration: 1569495377, states[0] = -94.970439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1583829772, states[0] = -70.894178, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1598136699, states[0] = 14.331830, states[40]= 0.006234
Saving checkpoint... 
Iteration: 1612397928, states[0] = -94.982600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1626733036, states[0] = -76.115360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1640941140, states[0] = -95.054319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1655254581, states[0] = -94.717652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1669532526, states[0] = 16.154514, states[40]= 0.006655
Saving checkpoint... 
Iteration: 1683803092, states[0] = -94.994830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1697023890, states[0] = -95.030862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1711201562, states[0] = 47.407311, states[40]= 0.049793
Saving checkpoint... 
Iteration: 1725484991, states[0] = -94.956575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1739708026, states[0] = 24.815959, states[40]= 0.079200
Saving checkpoint... 
Iteration: 1753995442, states[0] = -94.979593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1768307365, states[0] = -44.149242, states[40]= 0.000070
Saving checkpoint... 
Iteration: 1782648505, states[0] = 8.517388, states[40]= 0.005568
Saving checkpoint... 
Iteration: 1796969735, states[0] = -95.086160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1811100400, states[0] = -21.073882, states[40]= 0.000907
Saving checkpoint... 
Iteration: 1825393828, states[0] = -94.809946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1839607192, states[0] = -25.673309, states[40]= 0.000667
Saving checkpoint... 
Iteration: 1853908599, states[0] = -94.793016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1868111452, states[0] = -28.910717, states[40]= 0.000513
Saving checkpoint... 
Iteration: 1882380226, states[0] = -94.774516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1895799667, states[0] = -94.726824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1910088282, states[0] = -7.713432, states[40]= 0.002760
Saving checkpoint... 
Iteration: 1924361359, states[0] = -94.761889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1938660881, states[0] = -82.427961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1952950924, states[0] = -94.787363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1967132682, states[0] = -48.722830, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1981371900, states[0] = -94.764682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1995236899, states[0] = -94.649930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2009612897, states[0] = -29.732624, states[40]= 0.000474
Saving checkpoint... 
Iteration: 2023927208, states[0] = -94.781579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2038277791, states[0] = -94.701967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2052684592, states[0] = -94.514994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067004555, states[0] = 29.213673, states[40]= 0.148385
Saving checkpoint... 
Iteration: 2081358864, states[0] = -94.758703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2095083533, states[0] = -4.129965, states[40]= 0.003493
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.669626
 - CaMKt in component CaMK (millimolar): 0.006829
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.625155
 - nass in component intracellular_ions (millimolar): 6.625212
 - ki in component intracellular_ions (millimolar): 145.356439
 - kss in component intracellular_ions (millimolar): 145.356421
 - cansr in component intracellular_ions (millimolar): 1.294871
 - cajsr in component intracellular_ions (millimolar): 1.256813
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003704
 - hf in component INa (dimensionless): 0.875913
 - hs in component INa (dimensionless): 0.875908
 - j in component INa (dimensionless): 0.875878
 - hsp in component INa (dimensionless): 0.718172
 - jp in component INa (dimensionless): 0.875857
 - mL in component INaL (dimensionless): 0.000052
 - hL in component INaL (dimensionless): 0.702655
 - hLp in component INaL (dimensionless): 0.441787
 - a in component Ito (dimensionless): 0.000633
 - iF in component Ito (dimensionless): 0.999864
 - iS in component Ito (dimensionless): 0.616123
 - ap in component Ito (dimensionless): 0.000323
 - iFp in component Ito (dimensionless): 0.999864
 - iSp in component Ito (dimensionless): 0.689715
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934354
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999881
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001524
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.335255
 - xs1 in component IKs (dimensionless): 0.244725
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997398
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:10:01 (4856): called boinc_finish(0)

</stderr_txt>
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