𝕏

Task 55212615

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_760_1
Workunit 26219906
Created 28 Jun 2024, 6:04:19 UTC
Sent 29 Jun 2024, 3:58:37 UTC
Report deadline 2 Jul 2024, 6:51:25 UTC
Received 29 Jun 2024, 18:12:35 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216894
Run time 2 hours 51 min 20 sec
CPU time 2 hours 11 min 46 sec
Validate state Valid
Credit 48.10
Device peak FLOPS 4.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.78 MB
Peak swap size 32.60 GB
Peak disk usage 0.06 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_760.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_760_1_r1661492422_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_760_1_r1661492422_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 114.457360
     * GNaL_b in INaL: 0.004906
     * Gto_b in Ito: 0.093010
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032485
     * GKs_b in IKs: 0.001821
     * GK1_b in IK1: 0.040905
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 71.178403
     * GKb_b in IKb: 0.003682
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031594
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7639021, states[0] = -57.073815, states[40]= 0.000014
Saving checkpoint... 
Iteration: 14947455, states[0] = -91.423053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25900290, states[0] = -91.124048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36448476, states[0] = -91.108205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46992230, states[0] = -91.088032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57171882, states[0] = -72.088113, states[40]= 0.000001
Saving checkpoint... 
Iteration: 67463829, states[0] = -90.995527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77567924, states[0] = 9.418073, states[40]= 0.003815
Saving checkpoint... 
Iteration: 87464585, states[0] = -90.960239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96770660, states[0] = -89.678550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107376252, states[0] = -90.755756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118317357, states[0] = -90.416980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129101706, states[0] = -15.551321, states[40]= 0.001573
Saving checkpoint... 
Iteration: 139137513, states[0] = -50.351104, states[40]= 0.000070
Saving checkpoint... 
Iteration: 149816546, states[0] = -90.396988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160387101, states[0] = -90.770522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170844377, states[0] = -90.589525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177970854, states[0] = -90.922374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188412920, states[0] = -90.834768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198495107, states[0] = -90.938832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208675179, states[0] = -72.977543, states[40]= 0.000001
Saving checkpoint... 
Iteration: 218870290, states[0] = -90.706808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229086800, states[0] = -1.614224, states[40]= 0.004093
Saving checkpoint... 
Iteration: 239488963, states[0] = -90.933325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249907100, states[0] = -90.818847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260129471, states[0] = -42.998668, states[40]= 0.000208
Saving checkpoint... 
Iteration: 270746647, states[0] = -88.469843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281328672, states[0] = -90.484846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291230668, states[0] = -86.933757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301169665, states[0] = -70.656566, states[40]= 0.000002
Saving checkpoint... 
Iteration: 311262717, states[0] = -89.344913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321685552, states[0] = -76.757324, states[40]= 0.000001
Saving checkpoint... 
Iteration: 332008072, states[0] = 27.015824, states[40]= 0.091793
Saving checkpoint... 
Iteration: 342574491, states[0] = 6.177503, states[40]= 0.004191
Saving checkpoint... 
Iteration: 353593782, states[0] = -7.494937, states[40]= 0.003076
Saving checkpoint... 
Iteration: 364767884, states[0] = -89.534482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375628240, states[0] = -41.836749, states[40]= 0.000243
Saving checkpoint... 
Iteration: 386379809, states[0] = -90.739438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397318144, states[0] = -90.400819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406290132, states[0] = -90.064410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415960333, states[0] = -90.906754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426277734, states[0] = -89.815175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435752805, states[0] = -88.864888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446344420, states[0] = -90.583593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457093110, states[0] = -6.870441, states[40]= 0.003207
Saving checkpoint... 
Iteration: 468103263, states[0] = -17.093331, states[40]= 0.001398
Saving checkpoint... 
Iteration: 479372360, states[0] = -90.712184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490649710, states[0] = -59.708957, states[40]= 0.000014
Saving checkpoint... 
Iteration: 501757501, states[0] = -89.112810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512838151, states[0] = -90.546461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523404385, states[0] = -90.810383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533990396, states[0] = -90.932108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544640330, states[0] = -52.663394, states[40]= 0.000049
Saving checkpoint... 
Iteration: 555212048, states[0] = -83.879269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565918578, states[0] = -90.842002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576451509, states[0] = -90.895503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586387061, states[0] = -90.762035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596601785, states[0] = -15.551134, states[40]= 0.001574
Saving checkpoint... 
Iteration: 607511545, states[0] = 27.073380, states[40]= 0.028773
Saving checkpoint... 
Iteration: 618489744, states[0] = -90.931257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629443638, states[0] = -90.884657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639842374, states[0] = -90.570966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648714418, states[0] = -84.354069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657792590, states[0] = -90.102606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667193579, states[0] = -79.269970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677123732, states[0] = -37.534872, states[40]= 0.000419
Saving checkpoint... 
Iteration: 687839136, states[0] = -90.551567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698243834, states[0] = -88.253542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707629816, states[0] = -43.317669, states[40]= 0.000199
Saving checkpoint... 
Iteration: 717040523, states[0] = 20.927348, states[40]= 0.001846
Saving checkpoint... 
Iteration: 726350220, states[0] = -90.613223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734903945, states[0] = -90.808222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744664044, states[0] = -68.025772, states[40]= 0.000003
Saving checkpoint... 
Iteration: 754757536, states[0] = -89.112847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764665644, states[0] = -68.804284, states[40]= 0.000003
Saving checkpoint... 
Iteration: 776081420, states[0] = 2.104881, states[40]= 0.004327
Saving checkpoint... 
Iteration: 786873825, states[0] = -90.716088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797497506, states[0] = -90.935066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808004395, states[0] = 30.621410, states[40]= 0.309185
Saving checkpoint... 
Iteration: 818197004, states[0] = -80.244951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828761747, states[0] = -89.301750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839400112, states[0] = -90.797941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850251098, states[0] = -88.760763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860842386, states[0] = -90.569887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871752772, states[0] = -88.860038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881624567, states[0] = -38.336141, states[40]= 0.000381
Saving checkpoint... 
Iteration: 892000480, states[0] = -16.231365, states[40]= 0.000160
Saving checkpoint... 
Iteration: 902419448, states[0] = -90.842058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912868923, states[0] = -90.696678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923829043, states[0] = -90.483908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934684291, states[0] = -76.327445, states[40]= 0.000001
Saving checkpoint... 
Iteration: 945519388, states[0] = 26.866830, states[40]= 0.002944
Saving checkpoint... 
Iteration: 956435602, states[0] = -90.870856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967267495, states[0] = -89.517580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978156658, states[0] = -64.067334, states[40]= 0.000006
Saving checkpoint... 
Iteration: 988904470, states[0] = -90.808231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999597824, states[0] = -11.455387, states[40]= 0.002247
Saving checkpoint... 
Iteration: 1010170362, states[0] = -70.958298, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1019231189, states[0] = -86.991809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027955210, states[0] = -90.897781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036416334, states[0] = -90.834986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044745773, states[0] = -88.399977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053335426, states[0] = -90.526495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062334626, states[0] = -90.521270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071717840, states[0] = -84.991262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081416154, states[0] = -90.834380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090845663, states[0] = -90.587137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100200134, states[0] = -81.086131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109404073, states[0] = -90.806640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118899132, states[0] = -90.793947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128552508, states[0] = 16.320285, states[40]= 0.002661
Saving checkpoint... 
Iteration: 1138716483, states[0] = -84.743234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149656626, states[0] = -64.047914, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1161019144, states[0] = 26.898297, states[40]= 0.003105
Saving checkpoint... 
Iteration: 1171100495, states[0] = -14.204746, states[40]= 0.001764
Saving checkpoint... 
Iteration: 1181391881, states[0] = -90.773500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191428220, states[0] = -90.857197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201754292, states[0] = -88.943022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212092389, states[0] = -6.211161, states[40]= 0.003343
Saving checkpoint... 
Iteration: 1221957034, states[0] = -90.898954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231554534, states[0] = 15.494758, states[40]= 0.002818
Saving checkpoint... 
Iteration: 1240474465, states[0] = -90.916504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248689300, states[0] = -77.966473, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1256918343, states[0] = -90.838026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265565966, states[0] = 10.485213, states[40]= 0.003694
Saving checkpoint... 
Iteration: 1274925310, states[0] = -90.851491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284895697, states[0] = -90.783810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291949547, states[0] = -90.889375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303424295, states[0] = -90.849452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310489690, states[0] = -90.927740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321822452, states[0] = -90.431899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332917209, states[0] = -90.835309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339912625, states[0] = -90.825470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350455721, states[0] = -90.896764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360939166, states[0] = -90.874379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370945135, states[0] = -90.883026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380379627, states[0] = -90.733730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389639933, states[0] = -52.330805, states[40]= 0.000051
Saving checkpoint... 
Iteration: 1398790994, states[0] = -90.073019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407929174, states[0] = -90.857790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417433788, states[0] = -90.865583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427352149, states[0] = -90.619372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437622671, states[0] = -36.508457, states[40]= 0.000471
Saving checkpoint... 
Iteration: 1447352846, states[0] = -90.622734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457899583, states[0] = -90.793415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468330439, states[0] = -90.490910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478736954, states[0] = -87.629610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487615596, states[0] = -29.593049, states[40]= 0.000865
Saving checkpoint... 
Iteration: 1498187325, states[0] = -77.333830, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1507042716, states[0] = -34.244785, states[40]= 0.000753
Saving checkpoint... 
Iteration: 1513676316, states[0] = -86.492226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1523529733, states[0] = -53.473291, states[40]= 0.000060
Saving checkpoint... 
Iteration: 1530716648, states[0] = -91.208950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1540810133, states[0] = 14.004549, states[40]= 0.002159
Saving checkpoint... 
Iteration: 1550891702, states[0] = -89.963758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1561235722, states[0] = -81.764128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1571120987, states[0] = -23.973690, states[40]= 0.001098
Saving checkpoint... 
Iteration: 1581579073, states[0] = 8.806085, states[40]= 0.003343
Saving checkpoint... 
Iteration: 1590953842, states[0] = -88.397411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600637038, states[0] = -87.902999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1611314008, states[0] = -87.595788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1621915806, states[0] = -86.397113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1632494834, states[0] = -85.966661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1642935979, states[0] = -86.987472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1653403661, states[0] = -86.786053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1663777021, states[0] = -86.113670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1674273549, states[0] = -85.491201, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -84.945089
 - CaMKt in component CaMK (millimolar): 0.001063
 - cass in component intracellular_ions (millimolar): 0.000084
 - nai in component intracellular_ions (millimolar): 6.158626
 - nass in component intracellular_ions (millimolar): 6.158706
 - ki in component intracellular_ions (millimolar): 145.747527
 - kss in component intracellular_ions (millimolar): 145.747515
 - cansr in component intracellular_ions (millimolar): 1.517143
 - cajsr in component intracellular_ions (millimolar): 1.517347
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.009860
 - hf in component INa (dimensionless): 0.588172
 - hs in component INa (dimensionless): 0.588203
 - j in component INa (dimensionless): 0.588344
 - hsp in component INa (dimensionless): 0.340306
 - jp in component INa (dimensionless): 0.588426
 - mL in component INaL (dimensionless): 0.000329
 - hL in component INaL (dimensionless): 0.417087
 - hLp in component INaL (dimensionless): 0.240699
 - a in component Ito (dimensionless): 0.001220
 - iF in component Ito (dimensionless): 0.999255
 - iS in component Ito (dimensionless): 0.994381
 - ap in component Ito (dimensionless): 0.000622
 - iFp in component Ito (dimensionless): 0.999255
 - iSp in component Ito (dimensionless): 0.996736
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998874
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002635
 - xrf in component IKr (dimensionless): 0.000012
 - xrs in component IKr (dimensionless): 0.010548
 - xs1 in component IKs (dimensionless): 0.023841
 - xs2 in component IKs (dimensionless): 0.000268
 - xk1 in component IK1 (dimensionless): 0.999006
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:53:40 (6402): called boinc_finish(0)

</stderr_txt>
]]>


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