𝕏

Task 55212595

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_760_1
Workunit 26219896
Created 28 Jun 2024, 6:04:19 UTC
Sent 29 Jun 2024, 3:58:37 UTC
Report deadline 2 Jul 2024, 6:51:25 UTC
Received 29 Jun 2024, 15:36:56 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216894
Run time 2 hours 49 min 41 sec
CPU time 2 hours 11 min 26 sec
Validate state Valid
Credit 51.20
Device peak FLOPS 4.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.81 MB
Peak swap size 32.60 GB
Peak disk usage 0.07 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_760.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_760_1_r2034376326_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_760_1_r2034376326_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 114.457360
     * GNaL_b in INaL: 0.004906
     * Gto_b in Ito: 0.093010
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032485
     * GKs_b in IKs: 0.001821
     * GK1_b in IK1: 0.163620
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 71.178403
     * GKb_b in IKb: 0.003682
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031594
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7014386, states[0] = 26.522671, states[40]= 0.013639
Saving checkpoint... 
Iteration: 16660672, states[0] = -87.159356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26525212, states[0] = 25.248001, states[40]= 0.001872
Saving checkpoint... 
Iteration: 36152476, states[0] = -71.490936, states[40]= 0.000003
Saving checkpoint... 
Iteration: 46025158, states[0] = 25.347168, states[40]= 0.001720
Saving checkpoint... 
Iteration: 55708167, states[0] = -94.479242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66012174, states[0] = 26.860697, states[40]= 0.024684
Saving checkpoint... 
Iteration: 76397433, states[0] = -94.812849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86814126, states[0] = -94.738922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97037407, states[0] = 21.702559, states[40]= 0.002005
Saving checkpoint... 
Iteration: 107119145, states[0] = -34.204596, states[40]= 0.000654
Saving checkpoint... 
Iteration: 117106866, states[0] = -21.871838, states[40]= 0.001185
Saving checkpoint... 
Iteration: 126880588, states[0] = -94.801013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136661371, states[0] = -84.464381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146677987, states[0] = -94.216408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155957773, states[0] = -94.836015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163682712, states[0] = -94.332007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171197078, states[0] = -94.427052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178556638, states[0] = 14.280484, states[40]= 0.003433
Saving checkpoint... 
Iteration: 188782632, states[0] = -94.687807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198996396, states[0] = -94.845270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209464403, states[0] = -94.837604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219479177, states[0] = -94.841395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229072549, states[0] = 6.707837, states[40]= 0.004522
Saving checkpoint... 
Iteration: 238731479, states[0] = -94.560061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247346857, states[0] = -94.773529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256357513, states[0] = -94.782927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266155669, states[0] = -75.276012, states[40]= 0.000001
Saving checkpoint... 
Iteration: 276839868, states[0] = -94.766627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287793552, states[0] = -94.706459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298512647, states[0] = 26.883970, states[40]= 0.021179
Saving checkpoint... 
Iteration: 309125654, states[0] = -40.765826, states[40]= 0.000310
Saving checkpoint... 
Iteration: 318895402, states[0] = -94.808968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328550739, states[0] = 16.716981, states[40]= 0.002950
Saving checkpoint... 
Iteration: 337765421, states[0] = -94.651994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347044817, states[0] = 19.021056, states[40]= 0.002493
Saving checkpoint... 
Iteration: 356382069, states[0] = -94.800701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366281781, states[0] = -94.685456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376231897, states[0] = -94.560855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386373717, states[0] = -94.794905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396717774, states[0] = -94.511485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407105101, states[0] = -20.045544, states[40]= 0.001255
Saving checkpoint... 
Iteration: 417454216, states[0] = -94.833737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427929614, states[0] = -94.824965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438305629, states[0] = -94.724505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448708444, states[0] = -94.474744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459032728, states[0] = 23.268227, states[40]= 0.001774
Saving checkpoint... 
Iteration: 469227521, states[0] = -94.545972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478747469, states[0] = -94.606882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488560274, states[0] = 12.698918, states[40]= 0.003728
Saving checkpoint... 
Iteration: 498465235, states[0] = -94.836664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508590888, states[0] = -5.842858, states[40]= 0.003614
Saving checkpoint... 
Iteration: 519009202, states[0] = 26.895339, states[40]= 0.065822
Saving checkpoint... 
Iteration: 529514780, states[0] = 26.875170, states[40]= 0.010850
Saving checkpoint... 
Iteration: 539141448, states[0] = -57.549781, states[40]= 0.000027
Saving checkpoint... 
Iteration: 548647874, states[0] = -64.846144, states[40]= 0.000008
Saving checkpoint... 
Iteration: 558050358, states[0] = 16.869504, states[40]= 0.002920
Saving checkpoint... 
Iteration: 567549777, states[0] = 17.100523, states[40]= 0.002873
Saving checkpoint... 
Iteration: 576929110, states[0] = -94.824173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586282183, states[0] = -94.685332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595649894, states[0] = -67.317377, states[40]= 0.000005
Saving checkpoint... 
Iteration: 605176726, states[0] = -94.150473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614848227, states[0] = -94.773336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623823926, states[0] = -94.747793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632776318, states[0] = -94.673849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642868516, states[0] = -94.790102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653793999, states[0] = -94.705736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665084584, states[0] = -0.766290, states[40]= 0.004460
Saving checkpoint... 
Iteration: 675785120, states[0] = -94.690366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686724074, states[0] = -94.533193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697501399, states[0] = 49.206182, states[40]= 0.284058
Saving checkpoint... 
Iteration: 708029556, states[0] = 24.230489, states[40]= 0.001670
Saving checkpoint... 
Iteration: 718590187, states[0] = -5.225812, states[40]= 0.003744
Saving checkpoint... 
Iteration: 729242988, states[0] = -94.593315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740022977, states[0] = 25.876202, states[40]= 0.001953
Saving checkpoint... 
Iteration: 750729714, states[0] = -94.552200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761690129, states[0] = -94.390355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771532158, states[0] = 23.447763, states[40]= 0.001751
Saving checkpoint... 
Iteration: 782346752, states[0] = -94.771302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793367135, states[0] = -94.788466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804095403, states[0] = -10.100366, states[40]= 0.002654
Saving checkpoint... 
Iteration: 814891268, states[0] = -94.804605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825567284, states[0] = 9.423198, states[40]= 0.004237
Saving checkpoint... 
Iteration: 834635869, states[0] = -51.514679, states[40]= 0.000069
Saving checkpoint... 
Iteration: 844563988, states[0] = 11.005311, states[40]= 0.004011
Saving checkpoint... 
Iteration: 855154153, states[0] = -73.027134, states[40]= 0.000002
Saving checkpoint... 
Iteration: 865623971, states[0] = -39.041396, states[40]= 0.000384
Saving checkpoint... 
Iteration: 875595372, states[0] = -10.069423, states[40]= 0.002661
Saving checkpoint... 
Iteration: 885158555, states[0] = -79.836332, states[40]= 0.000001
Saving checkpoint... 
Iteration: 894995374, states[0] = -94.842275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905094476, states[0] = -9.189689, states[40]= 0.002859
Saving checkpoint... 
Iteration: 915237019, states[0] = -94.574846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925194043, states[0] = -94.409735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936088593, states[0] = -3.872940, states[40]= 0.004008
Saving checkpoint... 
Iteration: 947098452, states[0] = -13.181586, states[40]= 0.002030
Saving checkpoint... 
Iteration: 957894047, states[0] = -94.805664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968576859, states[0] = 4.275886, states[40]= 0.004651
Saving checkpoint... 
Iteration: 979140382, states[0] = -56.383144, states[40]= 0.000032
Saving checkpoint... 
Iteration: 989678037, states[0] = -94.214043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000232849, states[0] = -94.561426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010567465, states[0] = 9.334217, states[40]= 0.004249
Saving checkpoint... 
Iteration: 1020902718, states[0] = -94.810199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031183114, states[0] = -94.333511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041980780, states[0] = -94.838506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052583855, states[0] = -0.241738, states[40]= 0.004512
Saving checkpoint... 
Iteration: 1062564053, states[0] = 10.975209, states[40]= 0.004016
Saving checkpoint... 
Iteration: 1072348138, states[0] = -94.771441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083368002, states[0] = -94.787973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093865095, states[0] = -94.785712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104528416, states[0] = 24.553721, states[40]= 0.001652
Saving checkpoint... 
Iteration: 1115070298, states[0] = 7.901050, states[40]= 0.004414
Saving checkpoint... 
Iteration: 1124717213, states[0] = -94.506458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134642813, states[0] = -59.049277, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1145388569, states[0] = -94.801675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156313666, states[0] = -94.732787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167411962, states[0] = -94.814277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178370680, states[0] = -94.789583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189094794, states[0] = -9.499198, states[40]= 0.002789
Saving checkpoint... 
Iteration: 1199983457, states[0] = -94.838505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210799089, states[0] = -94.711641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221066465, states[0] = 9.824570, states[40]= 0.004184
Saving checkpoint... 
Iteration: 1231370033, states[0] = -94.788898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242340410, states[0] = -94.763340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253313198, states[0] = -94.731780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264213582, states[0] = -94.491982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275041858, states[0] = 20.124786, states[40]= 0.002287
Saving checkpoint... 
Iteration: 1285867837, states[0] = -94.787047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296486065, states[0] = -94.838714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306989666, states[0] = -94.839460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317692231, states[0] = -94.399221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328487580, states[0] = -94.838923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339191854, states[0] = -94.397212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350247855, states[0] = -94.604455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361118431, states[0] = -33.447637, states[40]= 0.000702
Saving checkpoint... 
Iteration: 1371951327, states[0] = -94.829052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381727877, states[0] = -94.543523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391177724, states[0] = -94.198673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400998921, states[0] = -94.840978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411322991, states[0] = -94.743551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421564738, states[0] = 10.653191, states[40]= 0.004065
Saving checkpoint... 
Iteration: 1431671569, states[0] = -93.462641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442211871, states[0] = -94.484543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448901147, states[0] = -94.807671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459874014, states[0] = -94.790867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470763109, states[0] = -94.642224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480842798, states[0] = -94.764754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487804325, states[0] = -94.718439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499305526, states[0] = -94.720143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506779796, states[0] = 22.017365, states[40]= 0.004971
Saving checkpoint... 
Iteration: 1516856944, states[0] = -30.789268, states[40]= 0.001111
Saving checkpoint... 
Iteration: 1527168823, states[0] = -94.837776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537958873, states[0] = -94.282843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1548522724, states[0] = -94.494673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1559137729, states[0] = -42.067001, states[40]= 0.000286
Saving checkpoint... 
Iteration: 1569749966, states[0] = -94.620951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1580136777, states[0] = -38.149367, states[40]= 0.000479
Saving checkpoint... 
Iteration: 1590144905, states[0] = -94.512702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600282775, states[0] = -94.507488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1610613339, states[0] = -94.491512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1620741402, states[0] = -94.430208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1631247528, states[0] = -94.414077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1641983666, states[0] = -94.397122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1652743980, states[0] = -94.049928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1660395782, states[0] = -94.320895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1667092931, states[0] = -94.384744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1677874966, states[0] = -94.296966, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.254729
 - CaMKt in component CaMK (millimolar): 0.001126
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.396022
 - nass in component intracellular_ions (millimolar): 6.396107
 - ki in component intracellular_ions (millimolar): 145.500176
 - kss in component intracellular_ions (millimolar): 145.500165
 - cansr in component intracellular_ions (millimolar): 1.568434
 - cajsr in component intracellular_ions (millimolar): 1.568518
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003863
 - hf in component INa (dimensionless): 0.868309
 - hs in component INa (dimensionless): 0.868309
 - j in component INa (dimensionless): 0.868311
 - hsp in component INa (dimensionless): 0.704197
 - jp in component INa (dimensionless): 0.868311
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.711775
 - hLp in component INaL (dimensionless): 0.518933
 - a in component Ito (dimensionless): 0.000651
 - iF in component Ito (dimensionless): 0.999854
 - iS in component Ito (dimensionless): 0.997768
 - ap in component Ito (dimensionless): 0.000332
 - iFp in component Ito (dimensionless): 0.999854
 - iSp in component Ito (dimensionless): 0.999259
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998920
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003011
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001774
 - xs1 in component IKs (dimensionless): 0.022089
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997502
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:00:56 (4169): called boinc_finish(0)

</stderr_txt>
]]>


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