𝕏

Task 55212592

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_60_0
Workunit 26219895
Created 28 Jun 2024, 6:04:19 UTC
Sent 29 Jun 2024, 3:58:37 UTC
Report deadline 2 Jul 2024, 6:51:25 UTC
Received 29 Jun 2024, 15:36:56 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216894
Run time 2 hours 48 min 52 sec
CPU time 2 hours 11 min 9 sec
Validate state Valid
Credit 49.39
Device peak FLOPS 4.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.77 MB
Peak swap size 32.60 GB
Peak disk usage 0.07 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_60.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_60_0_r411384794_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_60_0_r411384794_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 96.762087
     * GNaL_b in INaL: 0.006257
     * Gto_b in Ito: 0.073478
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.029765
     * GKs_b in IKs: 0.002058
     * GK1_b in IK1: 0.148517
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 72.393625
     * GKb_b in IKb: 0.003669
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025525
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7557256, states[0] = 14.636747, states[40]= 0.004483
Saving checkpoint... 
Iteration: 14960183, states[0] = -94.739834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25205328, states[0] = -94.291714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35421276, states[0] = -94.675844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45943676, states[0] = -94.677959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55973384, states[0] = -94.683703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65598964, states[0] = -7.995941, states[40]= 0.003198
Saving checkpoint... 
Iteration: 75265550, states[0] = -94.462930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83904078, states[0] = -94.647759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92881280, states[0] = -94.631317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102721048, states[0] = -94.313220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113349205, states[0] = -94.600980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124334251, states[0] = -94.583393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135048591, states[0] = 19.199811, states[40]= 0.002882
Saving checkpoint... 
Iteration: 145672266, states[0] = -79.369125, states[40]= 0.000001
Saving checkpoint... 
Iteration: 155485242, states[0] = -94.676542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165160119, states[0] = -64.349808, states[40]= 0.000010
Saving checkpoint... 
Iteration: 174398540, states[0] = -94.639896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183684813, states[0] = -92.627887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193008690, states[0] = 29.664484, states[40]= 0.073084
Saving checkpoint... 
Iteration: 202941986, states[0] = -94.661835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212891783, states[0] = -94.635118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223085337, states[0] = 2.134271, states[40]= 0.004868
Saving checkpoint... 
Iteration: 233446929, states[0] = -94.663599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243803054, states[0] = -94.536117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254178431, states[0] = -87.813138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264670966, states[0] = -77.453601, states[40]= 0.000001
Saving checkpoint... 
Iteration: 275047992, states[0] = 19.438376, states[40]= 0.002839
Saving checkpoint... 
Iteration: 285504016, states[0] = 35.321277, states[40]= 0.335847
Saving checkpoint... 
Iteration: 295921026, states[0] = -94.651868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306147043, states[0] = -51.350293, states[40]= 0.000083
Saving checkpoint... 
Iteration: 315680899, states[0] = -90.289376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325505990, states[0] = 31.263634, states[40]= 0.179254
Saving checkpoint... 
Iteration: 335473942, states[0] = -94.672244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345628438, states[0] = -34.160027, states[40]= 0.000815
Saving checkpoint... 
Iteration: 356066393, states[0] = 11.917695, states[40]= 0.004282
Saving checkpoint... 
Iteration: 366616884, states[0] = -23.988130, states[40]= 0.001375
Saving checkpoint... 
Iteration: 376261609, states[0] = -94.445612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385771840, states[0] = -94.471695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395198778, states[0] = -94.176613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404722414, states[0] = -94.315082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414098565, states[0] = -7.403881, states[40]= 0.003343
Saving checkpoint... 
Iteration: 423470381, states[0] = -94.670852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432853750, states[0] = -94.602613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442414530, states[0] = -94.647921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452111810, states[0] = -19.434177, states[40]= 0.001420
Saving checkpoint... 
Iteration: 461102610, states[0] = -10.966265, states[40]= 0.002517
Saving checkpoint... 
Iteration: 470091032, states[0] = -1.570192, states[40]= 0.004521
Saving checkpoint... 
Iteration: 480191137, states[0] = -93.885556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491114162, states[0] = -21.560934, states[40]= 0.001379
Saving checkpoint... 
Iteration: 502408543, states[0] = -94.644371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513092239, states[0] = -2.427650, states[40]= 0.004389
Saving checkpoint... 
Iteration: 524118157, states[0] = -25.113012, states[40]= 0.001366
Saving checkpoint... 
Iteration: 534892983, states[0] = -94.634605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545444386, states[0] = -94.661365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555988082, states[0] = -94.675218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566685856, states[0] = -92.978498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577484676, states[0] = -94.674269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588241507, states[0] = -94.384317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599186188, states[0] = -93.075553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609052859, states[0] = 17.561721, states[40]= 0.003230
Saving checkpoint... 
Iteration: 619859163, states[0] = -94.607182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630842874, states[0] = -94.590295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641617573, states[0] = -24.596897, states[40]= 0.001372
Saving checkpoint... 
Iteration: 652440624, states[0] = -94.659439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663176322, states[0] = -85.118136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672242804, states[0] = -94.388290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682189610, states[0] = -93.729998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692799578, states[0] = -94.528273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703258924, states[0] = -94.437003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713311607, states[0] = -94.548315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722906540, states[0] = -94.642373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732758385, states[0] = -94.435388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742843472, states[0] = -94.590537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752959606, states[0] = -94.666151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762956739, states[0] = -94.665129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773880616, states[0] = -94.624856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784879278, states[0] = -94.623789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795691313, states[0] = -93.898373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806452724, states[0] = -94.663535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817013812, states[0] = 29.209257, states[40]= 0.013844
Saving checkpoint... 
Iteration: 827588042, states[0] = 0.440918, states[40]= 0.004754
Saving checkpoint... 
Iteration: 838159376, states[0] = -63.541051, states[40]= 0.000011
Saving checkpoint... 
Iteration: 848478198, states[0] = -94.671498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858807279, states[0] = -94.540817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869116771, states[0] = -23.886315, states[40]= 0.001375
Saving checkpoint... 
Iteration: 879949001, states[0] = -94.661876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890517478, states[0] = 28.831532, states[40]= 0.004924
Saving checkpoint... 
Iteration: 900538113, states[0] = 23.083414, states[40]= 0.002154
Saving checkpoint... 
Iteration: 910361200, states[0] = -94.607985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921344392, states[0] = -94.590878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931880204, states[0] = -94.623939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942545063, states[0] = 20.543062, states[40]= 0.002618
Saving checkpoint... 
Iteration: 953147705, states[0] = -51.985079, states[40]= 0.000075
Saving checkpoint... 
Iteration: 962791803, states[0] = -94.512766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972731969, states[0] = -94.349464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983418213, states[0] = -94.647802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994401609, states[0] = -94.638386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005493678, states[0] = -94.674863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016506946, states[0] = 30.400522, states[40]= 0.130615
Saving checkpoint... 
Iteration: 1027276234, states[0] = -94.479582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038196953, states[0] = -94.141918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048943851, states[0] = -94.659234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059229843, states[0] = -94.341265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069667032, states[0] = -72.211214, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1080644096, states[0] = -48.518776, states[40]= 0.000128
Saving checkpoint... 
Iteration: 1091576877, states[0] = 6.875314, states[40]= 0.004821
Saving checkpoint... 
Iteration: 1102523304, states[0] = 27.699198, states[40]= 0.001967
Saving checkpoint... 
Iteration: 1113380762, states[0] = -94.623671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124271397, states[0] = -94.467782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134853440, states[0] = -94.599618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145359644, states[0] = -94.605630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156098080, states[0] = -6.991981, states[40]= 0.003440
Saving checkpoint... 
Iteration: 1166957657, states[0] = -94.663908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177687699, states[0] = -93.429136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188759521, states[0] = -94.436785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199644944, states[0] = -49.329354, states[40]= 0.000113
Saving checkpoint... 
Iteration: 1210517425, states[0] = 28.839328, states[40]= 0.004988
Saving checkpoint... 
Iteration: 1220296543, states[0] = -94.520746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229742662, states[0] = -94.385670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239609864, states[0] = -17.649729, states[40]= 0.001517
Saving checkpoint... 
Iteration: 1249931441, states[0] = -94.653196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260187213, states[0] = -93.327567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270286017, states[0] = -94.499994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280877878, states[0] = -94.620808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287555134, states[0] = 16.663162, states[40]= 0.003417
Saving checkpoint... 
Iteration: 1298560258, states[0] = 14.571826, states[40]= 0.003830
Saving checkpoint... 
Iteration: 1309463351, states[0] = -94.665273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319655354, states[0] = -59.450997, states[40]= 0.000022
Saving checkpoint... 
Iteration: 1326588140, states[0] = 0.378448, states[40]= 0.004749
Saving checkpoint... 
Iteration: 1338142933, states[0] = -47.409280, states[40]= 0.000150
Saving checkpoint... 
Iteration: 1345731318, states[0] = -94.345630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355972803, states[0] = -94.668022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366452761, states[0] = -94.661415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377476580, states[0] = -94.669030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388283054, states[0] = -94.493314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399174744, states[0] = -82.883828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410099404, states[0] = -8.119720, states[40]= 0.003172
Saving checkpoint... 
Iteration: 1420769809, states[0] = -94.462756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431026469, states[0] = 26.870670, states[40]= 0.001752
Saving checkpoint... 
Iteration: 1441448642, states[0] = -94.659601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452032221, states[0] = 25.107883, states[40]= 0.001854
Saving checkpoint... 
Iteration: 1462487813, states[0] = -94.671699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473435184, states[0] = -94.654006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484520284, states[0] = 28.360635, states[40]= 0.002769
Saving checkpoint... 
Iteration: 1495637871, states[0] = -42.657776, states[40]= 0.000292
Saving checkpoint... 
Iteration: 1503444938, states[0] = -95.322825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1510265658, states[0] = 29.358190, states[40]= 0.008054
Saving checkpoint... 
Iteration: 1521129634, states[0] = -94.148031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1528175272, states[0] = -94.669730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1538928475, states[0] = -94.499979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1549212702, states[0] = -94.045125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1559408550, states[0] = -94.370828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1569450958, states[0] = -94.382285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579348089, states[0] = -94.283278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1589200124, states[0] = -85.563181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1598488304, states[0] = -94.269939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1607972952, states[0] = -94.293661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1618433931, states[0] = -94.223611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628961883, states[0] = -94.196999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1639455967, states[0] = -94.181962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649162076, states[0] = -94.179501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1659526405, states[0] = -94.170406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1669861741, states[0] = -94.164069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1679928071, states[0] = -94.160827, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.036373
 - CaMKt in component CaMK (millimolar): 0.001131
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.356302
 - nass in component intracellular_ions (millimolar): 6.356388
 - ki in component intracellular_ions (millimolar): 145.541389
 - kss in component intracellular_ions (millimolar): 145.541379
 - cansr in component intracellular_ions (millimolar): 1.568228
 - cajsr in component intracellular_ions (millimolar): 1.568232
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003949
 - hf in component INa (dimensionless): 0.864152
 - hs in component INa (dimensionless): 0.864152
 - j in component INa (dimensionless): 0.864154
 - hsp in component INa (dimensionless): 0.696670
 - jp in component INa (dimensionless): 0.864155
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.705758
 - hLp in component INaL (dimensionless): 0.511650
 - a in component Ito (dimensionless): 0.000661
 - iF in component Ito (dimensionless): 0.999848
 - iS in component Ito (dimensionless): 0.997633
 - ap in component Ito (dimensionless): 0.000337
 - iFp in component Ito (dimensionless): 0.999848
 - iSp in component Ito (dimensionless): 0.999196
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998802
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003016
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001999
 - xs1 in component IKs (dimensionless): 0.023572
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997555
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:17:22 (4401): called boinc_finish(0)

</stderr_txt>
]]>


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