𝕏

Task 55212591

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_560_1
Workunit 26219894
Created 28 Jun 2024, 6:04:19 UTC
Sent 29 Jun 2024, 3:58:37 UTC
Report deadline 2 Jul 2024, 6:51:25 UTC
Received 29 Jun 2024, 7:38:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216894
Run time 2 hours 47 min 41 sec
CPU time 2 hours 9 min 29 sec
Validate state Valid
Credit 48.78
Device peak FLOPS 4.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.96 MB
Peak swap size 32.60 GB
Peak disk usage 0.07 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_560.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_560_1_r1009186513_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_560_1_r1009186513_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 94.739551
     * GNaL_b in INaL: 0.005560
     * Gto_b in Ito: 0.084119
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.031822
     * GKs_b in IKs: 0.002013
     * GK1_b in IK1: 0.171817
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 75.074022
     * GKb_b in IKb: 0.003748
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019240
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11870203, states[0] = -95.009743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24283674, states[0] = -94.862444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36664439, states[0] = -86.582567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48417379, states[0] = -94.961556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59560123, states[0] = 13.470576, states[40]= 0.003466
Saving checkpoint... 
Iteration: 71403752, states[0] = -94.947450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83394019, states[0] = -94.940078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93994118, states[0] = -94.974633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103995154, states[0] = -94.973943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114662154, states[0] = -80.232757, states[40]= 0.000001
Saving checkpoint... 
Iteration: 125224872, states[0] = -94.671313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135415146, states[0] = -94.947114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145878274, states[0] = -94.926269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156375719, states[0] = -94.924317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166888724, states[0] = -94.932489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177314838, states[0] = -94.866062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187519406, states[0] = 27.349409, states[40]= 0.003059
Saving checkpoint... 
Iteration: 197941812, states[0] = -94.956850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208456745, states[0] = -94.961646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219139805, states[0] = -51.290263, states[40]= 0.000073
Saving checkpoint... 
Iteration: 229835515, states[0] = -94.889535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240358429, states[0] = -94.910587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250683120, states[0] = -94.446862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261085349, states[0] = 0.419199, states[40]= 0.004502
Saving checkpoint... 
Iteration: 271609890, states[0] = -21.550928, states[40]= 0.001221
Saving checkpoint... 
Iteration: 281470812, states[0] = -94.965225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292106839, states[0] = -18.549691, states[40]= 0.001352
Saving checkpoint... 
Iteration: 302955574, states[0] = -94.960819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313458322, states[0] = -94.961605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324481189, states[0] = -94.967619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335355715, states[0] = -94.907924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346247166, states[0] = -94.736841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356729131, states[0] = -94.683328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367077118, states[0] = 5.418695, states[40]= 0.004539
Saving checkpoint... 
Iteration: 377539579, states[0] = 21.665908, states[40]= 0.001970
Saving checkpoint... 
Iteration: 387763355, states[0] = -94.776488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397906929, states[0] = -94.941206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408205355, states[0] = -94.595732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418346483, states[0] = -94.899457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428282356, states[0] = -94.814850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437938141, states[0] = -94.954441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447636093, states[0] = -47.353021, states[40]= 0.000131
Saving checkpoint... 
Iteration: 457201364, states[0] = -94.578873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466847226, states[0] = -94.899947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476473516, states[0] = -94.965135, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_560.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_560_1_r1009186513_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_560_1_r1009186513_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 94.739551
     * GNaL_b in INaL: 0.005560
     * Gto_b in Ito: 0.084119
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.031822
     * GKs_b in IKs: 0.002013
     * GK1_b in IK1: 0.171817
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 75.074022
     * GKb_b in IKb: 0.003748
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019240
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 476473516
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.965135 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 488501114, states[0] = 46.534627, states[40]= 0.208653
Saving checkpoint... 
Iteration: 499916606, states[0] = -94.945410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510196674, states[0] = -94.558075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519553382, states[0] = 16.423202, states[40]= 0.002958
Saving checkpoint... 
Iteration: 528847726, states[0] = -94.900156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538169385, states[0] = -90.836066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547471339, states[0] = -94.964292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558012811, states[0] = 27.830613, states[40]= 0.019173
Saving checkpoint... 
Iteration: 567184828, states[0] = -94.475377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577163326, states[0] = -82.053467, states[40]= 0.000001
Saving checkpoint... 
Iteration: 588053027, states[0] = 16.565436, states[40]= 0.002929
Saving checkpoint... 
Iteration: 598898069, states[0] = -94.935770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608728516, states[0] = -94.680299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619631061, states[0] = -42.165049, states[40]= 0.000268
Saving checkpoint... 
Iteration: 630577307, states[0] = 5.314265, states[40]= 0.004544
Saving checkpoint... 
Iteration: 641578821, states[0] = 4.459348, states[40]= 0.004578
Saving checkpoint... 
Iteration: 652396839, states[0] = -94.934880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663482528, states[0] = -94.966578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673423844, states[0] = -94.947885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682989192, states[0] = -94.967990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692662821, states[0] = -81.169877, states[40]= 0.000001
Saving checkpoint... 
Iteration: 702867512, states[0] = -94.915789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713724924, states[0] = -94.667869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724743192, states[0] = -94.724411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735706267, states[0] = -94.598127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746948354, states[0] = -94.956752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757897704, states[0] = -94.934936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768857167, states[0] = -94.907401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779969484, states[0] = -94.962879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791043479, states[0] = 20.242924, states[40]= 0.002216
Saving checkpoint... 
Iteration: 801889804, states[0] = -94.930249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811975578, states[0] = -94.964318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822192554, states[0] = -94.536862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832557837, states[0] = 14.599275, states[40]= 0.003319
Saving checkpoint... 
Iteration: 842973414, states[0] = -94.963649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852549352, states[0] = 18.012962, states[40]= 0.002640
Saving checkpoint... 
Iteration: 863019058, states[0] = 27.402280, states[40]= 0.003292
Saving checkpoint... 
Iteration: 873592023, states[0] = -4.527450, states[40]= 0.003832
Saving checkpoint... 
Iteration: 884119925, states[0] = -31.230017, states[40]= 0.000883
Saving checkpoint... 
Iteration: 894690965, states[0] = -94.527806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905111596, states[0] = -23.207816, states[40]= 0.001189
Saving checkpoint... 
Iteration: 915633959, states[0] = -45.128933, states[40]= 0.000179
Saving checkpoint... 
Iteration: 926069842, states[0] = 9.197270, states[40]= 0.004203
Saving checkpoint... 
Iteration: 936457017, states[0] = -94.958728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946909714, states[0] = -94.940390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956821566, states[0] = -94.871037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966878068, states[0] = -94.922188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977014246, states[0] = 27.812124, states[40]= 0.012168
Saving checkpoint... 
Iteration: 987032641, states[0] = 24.037998, states[40]= 0.001625
Saving checkpoint... 
Iteration: 996417107, states[0] = -94.943657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005849442, states[0] = -94.899802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015638348, states[0] = -49.729116, states[40]= 0.000092
Saving checkpoint... 
Iteration: 1025624077, states[0] = -35.246777, states[40]= 0.000614
Saving checkpoint... 
Iteration: 1036193738, states[0] = -94.542031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047049796, states[0] = 17.840602, states[40]= 0.002674
Saving checkpoint... 
Iteration: 1058140934, states[0] = -52.491277, states[40]= 0.000061
Saving checkpoint... 
Iteration: 1069372950, states[0] = -94.918265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080111900, states[0] = -23.501794, states[40]= 0.001185
Saving checkpoint... 
Iteration: 1090740048, states[0] = -94.713968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101127797, states[0] = -38.895603, states[40]= 0.000406
Saving checkpoint... 
Iteration: 1111300123, states[0] = -94.841582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121196761, states[0] = -94.555992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131072558, states[0] = 7.842554, states[40]= 0.004354
Saving checkpoint... 
Iteration: 1140853570, states[0] = -94.902883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151229872, states[0] = -94.682526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161962067, states[0] = -94.959313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173027847, states[0] = 25.485391, states[40]= 0.001513
Saving checkpoint... 
Iteration: 1184110442, states[0] = -22.085297, states[40]= 0.001209
Saving checkpoint... 
Iteration: 1194837093, states[0] = -94.887246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205673278, states[0] = -93.266382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215884081, states[0] = -94.925097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225761813, states[0] = -94.769626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235724722, states[0] = -94.665073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245597120, states[0] = -9.010764, states[40]= 0.002860
Saving checkpoint... 
Iteration: 1255153081, states[0] = -66.377641, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1263754669, states[0] = -94.752485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272234760, states[0] = -94.697448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281581435, states[0] = 2.918293, states[40]= 0.004597
Saving checkpoint... 
Iteration: 1290611568, states[0] = -23.179271, states[40]= 0.001190
Saving checkpoint... 
Iteration: 1300466545, states[0] = -94.960014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309611561, states[0] = -23.172414, states[40]= 0.001190
Saving checkpoint... 
Iteration: 1319668197, states[0] = -89.559659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330580881, states[0] = 3.252782, states[40]= 0.004598
Saving checkpoint... 
Iteration: 1341477086, states[0] = -94.962581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352238916, states[0] = -94.709610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362954456, states[0] = -94.956247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373361135, states[0] = -94.908205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384116864, states[0] = -28.283317, states[40]= 0.001051
Saving checkpoint... 
Iteration: 1394829566, states[0] = -94.878475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405246285, states[0] = -94.730199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415925317, states[0] = -94.945543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426819795, states[0] = -94.867016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437748916, states[0] = -94.737100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448306094, states[0] = -94.848936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457782179, states[0] = -94.810397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467392711, states[0] = -94.929297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477677781, states[0] = -94.179313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488215529, states[0] = -94.631202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498894508, states[0] = -94.930199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1502876511, states[0] = 21.365295, states[40]= 0.008649
Saving checkpoint... 
Iteration: 1510480925, states[0] = -95.229859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1518368542, states[0] = -94.856624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1529225052, states[0] = -94.983515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1540020456, states[0] = 26.527542, states[40]= 0.002023
Saving checkpoint... 
Iteration: 1550629016, states[0] = -33.915482, states[40]= 0.000753
Saving checkpoint... 
Iteration: 1561013165, states[0] = 26.670548, states[40]= 0.017225
Saving checkpoint... 
Iteration: 1571255851, states[0] = -94.470919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1580556680, states[0] = -94.670185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1590662862, states[0] = -55.064713, states[40]= 0.000044
Saving checkpoint... 
Iteration: 1600812622, states[0] = -94.643505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1610943925, states[0] = -94.643263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1621329164, states[0] = -94.572993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1631792721, states[0] = -94.557973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1642082072, states[0] = -94.548978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1652564008, states[0] = 16.681547, states[40]= 0.003307
Saving checkpoint... 
Iteration: 1663083176, states[0] = -94.544267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1673547217, states[0] = -94.550942, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.409208
 - CaMKt in component CaMK (millimolar): 0.001136
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.241822
 - nass in component intracellular_ions (millimolar): 6.241910
 - ki in component intracellular_ions (millimolar): 145.652510
 - kss in component intracellular_ions (millimolar): 145.652498
 - cansr in component intracellular_ions (millimolar): 1.574960
 - cajsr in component intracellular_ions (millimolar): 1.574955
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003803
 - hf in component INa (dimensionless): 0.871185
 - hs in component INa (dimensionless): 0.871185
 - j in component INa (dimensionless): 0.871186
 - hsp in component INa (dimensionless): 0.709457
 - jp in component INa (dimensionless): 0.871187
 - mL in component INaL (dimensionless): 0.000054
 - hL in component INaL (dimensionless): 0.715989
 - hLp in component INaL (dimensionless): 0.524076
 - a in component Ito (dimensionless): 0.000645
 - iF in component Ito (dimensionless): 0.999858
 - iS in component Ito (dimensionless): 0.997777
 - ap in component Ito (dimensionless): 0.000328
 - iFp in component Ito (dimensionless): 0.999858
 - iSp in component Ito (dimensionless): 0.999268
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998862
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003065
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001745
 - xs1 in component IKs (dimensionless): 0.022786
 - xs2 in component IKs (dimensionless): 0.000093
 - xk1 in component IK1 (dimensionless): 0.997464
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:53:51 (97763): called boinc_finish(0)

</stderr_txt>
]]>


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