𝕏

Task 55212589

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_460_1
Workunit 26219893
Created 28 Jun 2024, 6:04:19 UTC
Sent 29 Jun 2024, 3:58:37 UTC
Report deadline 2 Jul 2024, 6:51:25 UTC
Received 29 Jun 2024, 7:38:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216894
Run time 2 hours 48 min 4 sec
CPU time 2 hours 9 min 51 sec
Validate state Valid
Credit 53.92
Device peak FLOPS 4.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.78 MB
Peak swap size 32.60 GB
Peak disk usage 0.07 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_460.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_460_1_r534296217_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_460_1_r534296217_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 104.557588
     * GNaL_b in INaL: 0.006364
     * Gto_b in Ito: 0.085154
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033822
     * GKs_b in IKs: 0.001839
     * GK1_b in IK1: 0.150815
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 71.714367
     * GKb_b in IKb: 0.003864
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025980
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11172110, states[0] = -94.122909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23375524, states[0] = -94.852585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35681231, states[0] = -94.285990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47393711, states[0] = -94.840699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58502523, states[0] = 41.260126, states[40]= 0.463015
Saving checkpoint... 
Iteration: 70384864, states[0] = -94.829011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82383307, states[0] = -94.826374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93009932, states[0] = 27.688237, states[40]= 0.050054
Saving checkpoint... 
Iteration: 102975332, states[0] = -94.866374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113600552, states[0] = -14.474252, states[40]= 0.001819
Saving checkpoint... 
Iteration: 124124443, states[0] = -38.435530, states[40]= 0.000415
Saving checkpoint... 
Iteration: 134224892, states[0] = -94.537922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144656307, states[0] = -74.728932, states[40]= 0.000001
Saving checkpoint... 
Iteration: 155145478, states[0] = -61.137675, states[40]= 0.000015
Saving checkpoint... 
Iteration: 165607268, states[0] = -21.270730, states[40]= 0.001216
Saving checkpoint... 
Iteration: 176001331, states[0] = 48.338054, states[40]= 0.269510
Saving checkpoint... 
Iteration: 186160182, states[0] = -80.516311, states[40]= 0.000001
Saving checkpoint... 
Iteration: 196587293, states[0] = -2.238808, states[40]= 0.004310
Saving checkpoint... 
Iteration: 207019069, states[0] = 27.133969, states[40]= 0.003524
Saving checkpoint... 
Iteration: 217707906, states[0] = -94.467709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228367820, states[0] = -94.810827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238862471, states[0] = -94.806287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249140222, states[0] = -55.254354, states[40]= 0.000038
Saving checkpoint... 
Iteration: 259502274, states[0] = 42.980885, states[40]= 0.454024
Saving checkpoint... 
Iteration: 270040231, states[0] = 21.065347, states[40]= 0.002289
Saving checkpoint... 
Iteration: 279875006, states[0] = -94.816254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290447905, states[0] = -94.855261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301258010, states[0] = -94.641523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311671360, states[0] = -92.727538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322702589, states[0] = -94.443255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333550858, states[0] = 16.986864, states[40]= 0.003070
Saving checkpoint... 
Iteration: 344411830, states[0] = -94.839298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354847250, states[0] = -94.791605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365141029, states[0] = -56.143167, states[40]= 0.000033
Saving checkpoint... 
Iteration: 375618703, states[0] = -32.625558, states[40]= 0.000761
Saving checkpoint... 
Iteration: 385812095, states[0] = -94.748606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395933022, states[0] = -94.849048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406172900, states[0] = -93.256439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416303393, states[0] = -94.735171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426243544, states[0] = -94.599763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435861935, states[0] = -94.805045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445528837, states[0] = 24.884763, states[40]= 0.001757
Saving checkpoint... 
Iteration: 455073511, states[0] = 6.560240, states[40]= 0.004631
Saving checkpoint... 
Iteration: 464691781, states[0] = -94.386688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474245614, states[0] = -94.605893, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_460.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_460_1_r534296217_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_460_1_r534296217_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 104.557588
     * GNaL_b in INaL: 0.006364
     * Gto_b in Ito: 0.085154
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033822
     * GKs_b in IKs: 0.001839
     * GK1_b in IK1: 0.150815
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 71.714367
     * GKb_b in IKb: 0.003864
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025980
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 474245614
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.605893 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 486246068, states[0] = -94.607213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497648475, states[0] = -64.576157, states[40]= 0.000008
Saving checkpoint... 
Iteration: 507872767, states[0] = -94.813662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517205670, states[0] = -94.456554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526465804, states[0] = -94.860260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535770737, states[0] = -94.671883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545036443, states[0] = 22.420081, states[40]= 0.002062
Saving checkpoint... 
Iteration: 555575323, states[0] = 5.558842, states[40]= 0.004687
Saving checkpoint... 
Iteration: 564730294, states[0] = -94.555307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574691378, states[0] = -94.383666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585530477, states[0] = 24.390867, states[40]= 0.001796
Saving checkpoint... 
Iteration: 596373188, states[0] = -94.813652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606185362, states[0] = -94.327437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617036664, states[0] = 22.342983, states[40]= 0.002075
Saving checkpoint... 
Iteration: 627914689, states[0] = -94.839691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638845862, states[0] = -94.789114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649609315, states[0] = -23.309666, states[40]= 0.001163
Saving checkpoint... 
Iteration: 660755009, states[0] = -94.632108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670669771, states[0] = -91.938212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680218623, states[0] = -94.510846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689886530, states[0] = -94.822936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700049480, states[0] = 17.537407, states[40]= 0.002961
Saving checkpoint... 
Iteration: 710899989, states[0] = -94.831341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721873539, states[0] = -94.813446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732826922, states[0] = -94.767318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744051597, states[0] = 16.689582, states[40]= 0.003130
Saving checkpoint... 
Iteration: 755011498, states[0] = 27.653617, states[40]= 0.029892
Saving checkpoint... 
Iteration: 765988685, states[0] = -94.865450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777046455, states[0] = 18.722526, states[40]= 0.002726
Saving checkpoint... 
Iteration: 788074647, states[0] = 5.936989, states[40]= 0.004669
Saving checkpoint... 
Iteration: 798955750, states[0] = -94.856048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809009778, states[0] = 27.712085, states[40]= 0.052642
Saving checkpoint... 
Iteration: 819167386, states[0] = -90.152082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829488927, states[0] = -94.865266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839889316, states[0] = -94.824220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849447933, states[0] = -94.853145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859913559, states[0] = -94.838235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870437385, states[0] = -94.849043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880954322, states[0] = -94.855258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891509137, states[0] = 27.775095, states[40]= 0.065124
Saving checkpoint... 
Iteration: 901931242, states[0] = -94.846374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912455175, states[0] = -94.855426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922862336, states[0] = -94.803542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933239542, states[0] = -94.585199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943687983, states[0] = -94.356056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953542480, states[0] = 20.234685, states[40]= 0.002439
Saving checkpoint... 
Iteration: 963642180, states[0] = -57.414418, states[40]= 0.000027
Saving checkpoint... 
Iteration: 973733408, states[0] = -94.564621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983725794, states[0] = -94.537332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993087623, states[0] = -2.488403, states[40]= 0.004272
Saving checkpoint... 
Iteration: 1002521986, states[0] = 26.617600, states[40]= 0.002236
Saving checkpoint... 
Iteration: 1012281123, states[0] = -94.692522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022230556, states[0] = -94.554478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032763263, states[0] = -94.652155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043577427, states[0] = 4.350000, states[40]= 0.004727
Saving checkpoint... 
Iteration: 1054636246, states[0] = -50.886729, states[40]= 0.000076
Saving checkpoint... 
Iteration: 1065925740, states[0] = -94.843328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076630868, states[0] = -45.074889, states[40]= 0.000175
Saving checkpoint... 
Iteration: 1087210699, states[0] = -94.476443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097620485, states[0] = -34.399363, states[40]= 0.000646
Saving checkpoint... 
Iteration: 1107822909, states[0] = -94.760774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117658992, states[0] = -78.660958, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1127527243, states[0] = 25.340490, states[40]= 0.001749
Saving checkpoint... 
Iteration: 1137303114, states[0] = -94.731974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147706864, states[0] = -94.459456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158409988, states[0] = -94.835238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169450009, states[0] = -94.852674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180547085, states[0] = 18.478674, states[40]= 0.002774
Saving checkpoint... 
Iteration: 1191264446, states[0] = -94.654469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202087303, states[0] = -2.241335, states[40]= 0.004309
Saving checkpoint... 
Iteration: 1212297427, states[0] = -94.722256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222146281, states[0] = -62.024154, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1232085836, states[0] = -1.142068, states[40]= 0.004458
Saving checkpoint... 
Iteration: 1241911549, states[0] = -94.835744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251461407, states[0] = -94.856163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260078508, states[0] = 3.707343, states[40]= 0.004735
Saving checkpoint... 
Iteration: 1268545164, states[0] = 19.219793, states[40]= 0.002630
Saving checkpoint... 
Iteration: 1277895518, states[0] = -94.826498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286906968, states[0] = -94.833120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296718726, states[0] = -94.508882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305811681, states[0] = -94.744494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315854714, states[0] = -94.795200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326751618, states[0] = -94.620154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337595402, states[0] = -9.276879, states[40]= 0.002849
Saving checkpoint... 
Iteration: 1348361535, states[0] = -94.801230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359078789, states[0] = 3.537792, states[40]= 0.004735
Saving checkpoint... 
Iteration: 1369502568, states[0] = 40.995304, states[40]= 0.460567
Saving checkpoint... 
Iteration: 1380305402, states[0] = -94.734682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390967784, states[0] = -94.857572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401355173, states[0] = -94.795303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411990499, states[0] = -94.863425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422858034, states[0] = -94.797843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433749120, states[0] = -94.612589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444242323, states[0] = -94.592064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453718395, states[0] = -94.506955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463310242, states[0] = -94.741767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473576187, states[0] = 5.070000, states[40]= 0.004708
Saving checkpoint... 
Iteration: 1484093817, states[0] = -7.774428, states[40]= 0.003196
Saving checkpoint... 
Iteration: 1494722242, states[0] = -94.521911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498784631, states[0] = -94.697692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506325010, states[0] = -95.257284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1514337099, states[0] = -18.872582, states[40]= 0.001805
Saving checkpoint... 
Iteration: 1525205093, states[0] = -94.895389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1535955460, states[0] = -94.466653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1546504064, states[0] = -94.723174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1556862204, states[0] = -94.648358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1567088981, states[0] = 1.682560, states[40]= 0.004427
Saving checkpoint... 
Iteration: 1576337256, states[0] = -94.473861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1586370190, states[0] = -94.404299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1596525230, states[0] = 25.929360, states[40]= 0.001771
Saving checkpoint... 
Iteration: 1606623967, states[0] = -94.481165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1616946664, states[0] = -94.476387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1627328075, states[0] = -94.379568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1637577788, states[0] = 10.667403, states[40]= 0.004296
Saving checkpoint... 
Iteration: 1648057567, states[0] = -94.366934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1658518910, states[0] = -94.374688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1668882035, states[0] = -94.362116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1677263249, states[0] = -94.348868, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.222585
 - CaMKt in component CaMK (millimolar): 0.001121
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.306119
 - nass in component intracellular_ions (millimolar): 6.306205
 - ki in component intracellular_ions (millimolar): 145.591850
 - kss in component intracellular_ions (millimolar): 145.591838
 - cansr in component intracellular_ions (millimolar): 1.566160
 - cajsr in component intracellular_ions (millimolar): 1.566182
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003875
 - hf in component INa (dimensionless): 0.867704
 - hs in component INa (dimensionless): 0.867704
 - j in component INa (dimensionless): 0.867706
 - hsp in component INa (dimensionless): 0.703096
 - jp in component INa (dimensionless): 0.867706
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.710896
 - hLp in component INaL (dimensionless): 0.517871
 - a in component Ito (dimensionless): 0.000653
 - iF in component Ito (dimensionless): 0.999853
 - iS in component Ito (dimensionless): 0.997753
 - ap in component Ito (dimensionless): 0.000332
 - iFp in component Ito (dimensionless): 0.999853
 - iSp in component Ito (dimensionless): 0.999251
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998892
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003000
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001812
 - xs1 in component IKs (dimensionless): 0.022354
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997510
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:54:38 (97766): called boinc_finish(0)

</stderr_txt>
]]>


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