𝕏

Task 55212587

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_260_1
Workunit 26219892
Created 28 Jun 2024, 6:04:19 UTC
Sent 29 Jun 2024, 3:58:37 UTC
Report deadline 2 Jul 2024, 6:51:25 UTC
Received 29 Jun 2024, 7:38:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216894
Run time 2 hours 48 min 11 sec
CPU time 2 hours 9 min 54 sec
Validate state Valid
Credit 46.93
Device peak FLOPS 4.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.85 MB
Peak swap size 32.60 GB
Peak disk usage 0.07 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_260.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_260_1_r584617514_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_260_1_r584617514_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 96.542276
     * GNaL_b in INaL: 0.004697
     * Gto_b in Ito: 0.092691
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033666
     * GKs_b in IKs: 0.002055
     * GK1_b in IK1: 0.152482
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 69.768826
     * GKb_b in IKb: 0.003707
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.042533
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10652892, states[0] = -80.432664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22904663, states[0] = -94.848006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35111020, states[0] = -28.061596, states[40]= 0.000870
Saving checkpoint... 
Iteration: 46847357, states[0] = -94.787316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57918537, states[0] = -94.834765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69747813, states[0] = -94.608260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81685393, states[0] = -94.343444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92314534, states[0] = -94.743685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102269267, states[0] = -94.661803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112870277, states[0] = -94.801715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123361158, states[0] = -94.794049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133438005, states[0] = -94.839274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143828964, states[0] = -94.761070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154294584, states[0] = -94.711287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164737341, states[0] = -94.573082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175121686, states[0] = -38.812162, states[40]= 0.000346
Saving checkpoint... 
Iteration: 185276527, states[0] = -94.676495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195673964, states[0] = -93.987984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206131750, states[0] = -49.651399, states[40]= 0.000080
Saving checkpoint... 
Iteration: 216807226, states[0] = -94.731269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227418307, states[0] = -94.830022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237856020, states[0] = -94.788548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248100034, states[0] = -15.952593, states[40]= 0.001509
Saving checkpoint... 
Iteration: 258424221, states[0] = -94.832603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268895422, states[0] = -94.817564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278662843, states[0] = -88.907562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289238601, states[0] = -94.576466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300033978, states[0] = 22.798325, states[40]= 0.001401
Saving checkpoint... 
Iteration: 310402802, states[0] = -94.821650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321399902, states[0] = -94.819961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332185491, states[0] = -94.341051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343012339, states[0] = 26.821791, states[40]= 0.022562
Saving checkpoint... 
Iteration: 353450525, states[0] = -94.842506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363721004, states[0] = -94.513870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374137146, states[0] = -55.556769, states[40]= 0.000032
Saving checkpoint... 
Iteration: 384275534, states[0] = -94.673438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394386283, states[0] = -94.811257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404616499, states[0] = -33.357833, states[40]= 0.000618
Saving checkpoint... 
Iteration: 414724248, states[0] = -94.526011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424610673, states[0] = -27.266970, states[40]= 0.000915
Saving checkpoint... 
Iteration: 434202355, states[0] = -94.434314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443834005, states[0] = -94.765352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453332205, states[0] = -94.763251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462921251, states[0] = -94.830355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472457079, states[0] = -94.844153, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_260.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_260_1_r584617514_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET-conf_260_1_r584617514_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 96.542276
     * GNaL_b in INaL: 0.004697
     * Gto_b in Ito: 0.092691
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033666
     * GKs_b in IKs: 0.002055
     * GK1_b in IK1: 0.152482
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 69.768826
     * GKb_b in IKb: 0.003707
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.042533
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 472457079
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.844153 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 484443726, states[0] = -94.839529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495779898, states[0] = -94.682035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506057347, states[0] = 13.753972, states[40]= 0.002916
Saving checkpoint... 
Iteration: 515401095, states[0] = -94.819797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524653797, states[0] = -75.807213, states[40]= 0.000001
Saving checkpoint... 
Iteration: 533943658, states[0] = -94.839289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543219587, states[0] = -94.507545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553732825, states[0] = -94.556139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562913788, states[0] = -94.826341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572878071, states[0] = -94.804831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583711412, states[0] = -94.473886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594536418, states[0] = 21.966388, states[40]= 0.001507
Saving checkpoint... 
Iteration: 604367097, states[0] = -94.796360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615215846, states[0] = -94.492238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626187322, states[0] = -94.353771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637078208, states[0] = 3.122787, states[40]= 0.004200
Saving checkpoint... 
Iteration: 647848945, states[0] = -94.780135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658996338, states[0] = -94.853602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668928674, states[0] = -94.832760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678478777, states[0] = -94.849454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688136124, states[0] = -54.433368, states[40]= 0.000038
Saving checkpoint... 
Iteration: 698315160, states[0] = -94.740602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709132710, states[0] = -50.695601, states[40]= 0.000068
Saving checkpoint... 
Iteration: 720149423, states[0] = -69.791092, states[40]= 0.000003
Saving checkpoint... 
Iteration: 731136218, states[0] = -54.536179, states[40]= 0.000038
Saving checkpoint... 
Iteration: 742365160, states[0] = -94.794188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753330572, states[0] = -94.760040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764326783, states[0] = -94.755449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775430742, states[0] = -94.833173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786478026, states[0] = -94.848793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797349629, states[0] = -94.780145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807436121, states[0] = -94.835226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817629912, states[0] = -47.640456, states[40]= 0.000107
Saving checkpoint... 
Iteration: 827974405, states[0] = -94.847668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838376824, states[0] = -94.802775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847927185, states[0] = -94.831340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858382214, states[0] = -94.806499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868932553, states[0] = -94.833518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879419118, states[0] = -94.827550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889946968, states[0] = -94.838937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900385924, states[0] = -94.808819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910930100, states[0] = -94.832314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921354534, states[0] = -94.784207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931715666, states[0] = -94.490105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942161868, states[0] = -87.749979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952044487, states[0] = 18.997729, states[40]= 0.001960
Saving checkpoint... 
Iteration: 962149433, states[0] = -69.801652, states[40]= 0.000003
Saving checkpoint... 
Iteration: 972227092, states[0] = -94.534058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982215433, states[0] = -94.488928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991569564, states[0] = 8.005578, states[40]= 0.003834
Saving checkpoint... 
Iteration: 1000969851, states[0] = -94.845675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010709665, states[0] = -94.464496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020664210, states[0] = -90.271099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031206594, states[0] = -94.450920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042022537, states[0] = 25.963653, states[40]= 0.001655
Saving checkpoint... 
Iteration: 1053107721, states[0] = -24.164593, states[40]= 0.001006
Saving checkpoint... 
Iteration: 1064344603, states[0] = -94.774016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075039180, states[0] = 20.983492, states[40]= 0.001646
Saving checkpoint... 
Iteration: 1085622319, states[0] = -39.472624, states[40]= 0.000320
Saving checkpoint... 
Iteration: 1095996094, states[0] = -94.851654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106155915, states[0] = -78.983138, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1116011571, states[0] = 26.788049, states[40]= 0.029087
Saving checkpoint... 
Iteration: 1125887288, states[0] = -94.808735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135664265, states[0] = -90.319025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146075483, states[0] = 4.763806, states[40]= 0.004132
Saving checkpoint... 
Iteration: 1156790744, states[0] = -94.699919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167804956, states[0] = -94.723620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178917322, states[0] = -94.825393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189590619, states[0] = -6.285093, states[40]= 0.003285
Saving checkpoint... 
Iteration: 1200437701, states[0] = -94.834141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210669428, states[0] = -93.194368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220524009, states[0] = 25.651094, states[40]= 0.001432
Saving checkpoint... 
Iteration: 1230481903, states[0] = -94.847838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240308588, states[0] = -94.728808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249868426, states[0] = -94.794611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258468305, states[0] = -94.844122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266947069, states[0] = -94.837336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276248858, states[0] = -94.603295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285258793, states[0] = -94.630249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295056278, states[0] = 14.216590, states[40]= 0.002831
Saving checkpoint... 
Iteration: 1304149888, states[0] = -70.388809, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1314201340, states[0] = -94.425696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325131497, states[0] = -49.366550, states[40]= 0.000083
Saving checkpoint... 
Iteration: 1336013342, states[0] = 26.854467, states[40]= 0.016252
Saving checkpoint... 
Iteration: 1346722086, states[0] = -94.513705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357437009, states[0] = -94.833188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367796524, states[0] = -94.709101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378616502, states[0] = -33.356579, states[40]= 0.000618
Saving checkpoint... 
Iteration: 1389267379, states[0] = -94.650832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399670462, states[0] = -93.459967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410357197, states[0] = -94.784480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421175726, states[0] = -94.110142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432076601, states[0] = 4.104635, states[40]= 0.004167
Saving checkpoint... 
Iteration: 1442569620, states[0] = 7.977467, states[40]= 0.003837
Saving checkpoint... 
Iteration: 1452022130, states[0] = 26.044094, states[40]= 0.001744
Saving checkpoint... 
Iteration: 1461633994, states[0] = -52.095859, states[40]= 0.000055
Saving checkpoint... 
Iteration: 1471883181, states[0] = -94.804492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482417087, states[0] = -94.823961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493042974, states[0] = 19.575776, states[40]= 0.001865
Saving checkpoint... 
Iteration: 1497084109, states[0] = -0.872519, states[40]= 0.004082
Saving checkpoint... 
Iteration: 1504664098, states[0] = -66.226681, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1512639943, states[0] = -90.131234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1523550343, states[0] = -88.310383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1534339623, states[0] = -6.905268, states[40]= 0.002981
Saving checkpoint... 
Iteration: 1544887535, states[0] = -94.658723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1555269359, states[0] = -94.395906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1565478151, states[0] = -94.588066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1574744021, states[0] = -94.605491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1584830612, states[0] = -94.351225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1594976102, states[0] = -94.479627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1605043372, states[0] = -94.477399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1615436018, states[0] = -94.470382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1625861885, states[0] = -94.396635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636124811, states[0] = -94.381740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1646562640, states[0] = -94.365770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1656974720, states[0] = -94.355042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1667345438, states[0] = -94.347710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1675728584, states[0] = -94.365224, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.218579
 - CaMKt in component CaMK (millimolar): 0.001128
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.368314
 - nass in component intracellular_ions (millimolar): 6.368400
 - ki in component intracellular_ions (millimolar): 145.524072
 - kss in component intracellular_ions (millimolar): 145.524061
 - cansr in component intracellular_ions (millimolar): 1.570169
 - cajsr in component intracellular_ions (millimolar): 1.570220
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003877
 - hf in component INa (dimensionless): 0.867629
 - hs in component INa (dimensionless): 0.867629
 - j in component INa (dimensionless): 0.867630
 - hsp in component INa (dimensionless): 0.702959
 - jp in component INa (dimensionless): 0.867631
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.710785
 - hLp in component INaL (dimensionless): 0.517736
 - a in component Ito (dimensionless): 0.000653
 - iF in component Ito (dimensionless): 0.999853
 - iS in component Ito (dimensionless): 0.997772
 - ap in component Ito (dimensionless): 0.000333
 - iFp in component Ito (dimensionless): 0.999853
 - iSp in component Ito (dimensionless): 0.999259
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998931
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003025
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001759
 - xs1 in component IKs (dimensionless): 0.021906
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997511
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:55:07 (97767): called boinc_finish(0)

</stderr_txt>
]]>


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