𝕏

Task 55212585

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-BASE_MID-conf_960_1
Workunit 26219891
Created 28 Jun 2024, 6:04:19 UTC
Sent 29 Jun 2024, 3:58:37 UTC
Report deadline 2 Jul 2024, 3:58:37 UTC
Received 29 Jun 2024, 18:12:35 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216894
Run time 2 hours 32 min 18 sec
CPU time 1 hours 56 min 46 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 4.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.87 MB
Peak swap size 32.60 GB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-BASE_MID-conf_960.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-BASE_MID-conf_960_1_r1762237574_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-BASE_MID-conf_960_1_r1762237574_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 94.313603
     * GNaL_b in INaL: 0.006911
     * Gto_b in Ito: 0.095866
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030535
     * GKs_b in IKs: 0.001888
     * GK1_b in IK1: 0.166575
     * Gncx_b in INaCa_i: 0.000959
     * Pnak_b in INaK: 66.580718
     * GKb_b in IKb: 0.003791
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.040182
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 3859300, states[0] = -86.815172, states[40]= 0.000001
Saving checkpoint... 
Iteration: 11627051, states[0] = 0.136836, states[40]= 0.000083
Saving checkpoint... 
Iteration: 22052118, states[0] = 28.206267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33066892, states[0] = 22.830373, states[40]= 0.000001
Saving checkpoint... 
Iteration: 43603923, states[0] = 6.757171, states[40]= 0.000066
Saving checkpoint... 
Iteration: 54134127, states[0] = -12.406007, states[40]= 0.000387
Saving checkpoint... 
Iteration: 64408717, states[0] = -86.941322, states[40]= 0.000002
Saving checkpoint... 
Iteration: 74774249, states[0] = -86.662481, states[40]= 0.000001
Saving checkpoint... 
Iteration: 84923040, states[0] = -86.970278, states[40]= 0.000002
Saving checkpoint... 
Iteration: 94840182, states[0] = -86.872214, states[40]= 0.000002
Saving checkpoint... 
Iteration: 104202063, states[0] = -84.806158, states[40]= 0.000001
Saving checkpoint... 
Iteration: 114862302, states[0] = -86.916766, states[40]= 0.000002
Saving checkpoint... 
Iteration: 125878657, states[0] = -86.941078, states[40]= 0.000002
Saving checkpoint... 
Iteration: 136656557, states[0] = -34.052542, states[40]= 0.001249
Saving checkpoint... 
Iteration: 146726489, states[0] = -86.405951, states[40]= 0.000001
Saving checkpoint... 
Iteration: 157474896, states[0] = -87.015210, states[40]= 0.000002
Saving checkpoint... 
Iteration: 168123885, states[0] = -8.532596, states[40]= 0.000426
Saving checkpoint... 
Iteration: 178645777, states[0] = -25.851704, states[40]= 0.001246
Saving checkpoint... 
Iteration: 185818164, states[0] = -86.834184, states[40]= 0.000002
Saving checkpoint... 
Iteration: 196352492, states[0] = -86.904629, states[40]= 0.000002
Saving checkpoint... 
Iteration: 206474092, states[0] = -87.013413, states[40]= 0.000002
Saving checkpoint... 
Iteration: 216678229, states[0] = -55.882904, states[40]= 0.000135
Saving checkpoint... 
Iteration: 226900628, states[0] = -86.964580, states[40]= 0.000002
Saving checkpoint... 
Iteration: 237206613, states[0] = -86.062339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247649697, states[0] = -28.948054, states[40]= 0.001418
Saving checkpoint... 
Iteration: 258118234, states[0] = -4.455512, states[40]= 0.000375
Saving checkpoint... 
Iteration: 268394907, states[0] = -86.956042, states[40]= 0.000002
Saving checkpoint... 
Iteration: 279070037, states[0] = 19.755789, states[40]= 0.000003
Saving checkpoint... 
Iteration: 289660514, states[0] = -37.984802, states[40]= 0.000966
Saving checkpoint... 
Iteration: 299602279, states[0] = 5.012846, states[40]= 0.000123
Saving checkpoint... 
Iteration: 309586185, states[0] = 12.825029, states[40]= 0.000024
Saving checkpoint... 
Iteration: 319731453, states[0] = -86.434363, states[40]= 0.000001
Saving checkpoint... 
Iteration: 330255210, states[0] = -86.584806, states[40]= 0.000001
Saving checkpoint... 
Iteration: 340669184, states[0] = -46.244659, states[40]= 0.000436
Saving checkpoint... 
Iteration: 351289846, states[0] = -86.737613, states[40]= 0.000002
Saving checkpoint... 
Iteration: 362338564, states[0] = -86.867614, states[40]= 0.000002
Saving checkpoint... 
Iteration: 373528235, states[0] = 30.961098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384452024, states[0] = -86.990322, states[40]= 0.000002
Saving checkpoint... 
Iteration: 395252075, states[0] = -86.562226, states[40]= 0.000001
Saving checkpoint... 
Iteration: 406227644, states[0] = -86.399042, states[40]= 0.000001
Saving checkpoint... 
Iteration: 415260899, states[0] = -86.608377, states[40]= 0.000001
Saving checkpoint... 
Iteration: 424955668, states[0] = -86.989150, states[40]= 0.000002
Saving checkpoint... 
Iteration: 435329739, states[0] = -86.843698, states[40]= 0.000002
Saving checkpoint... 
Iteration: 444852627, states[0] = -86.886908, states[40]= 0.000002
Saving checkpoint... 
Iteration: 455560492, states[0] = 23.371494, states[40]= 0.000001
Saving checkpoint... 
Iteration: 466368261, states[0] = -86.909179, states[40]= 0.000002
Saving checkpoint... 
Iteration: 477473327, states[0] = -86.993332, states[40]= 0.000002
Saving checkpoint... 
Iteration: 488802741, states[0] = -86.769590, states[40]= 0.000002
Saving checkpoint... 
Iteration: 500169440, states[0] = -46.481451, states[40]= 0.000423
Saving checkpoint... 
Iteration: 511255036, states[0] = -86.569815, states[40]= 0.000001
Saving checkpoint... 
Iteration: 522375470, states[0] = -86.914565, states[40]= 0.000002
Saving checkpoint... 
Iteration: 532983204, states[0] = -86.993006, states[40]= 0.000002
Saving checkpoint... 
Iteration: 543621203, states[0] = -6.585018, states[40]= 0.000409
Saving checkpoint... 
Iteration: 554240356, states[0] = -86.477904, states[40]= 0.000001
Saving checkpoint... 
Iteration: 564881589, states[0] = -86.918925, states[40]= 0.000002
Saving checkpoint... 
Iteration: 575640704, states[0] = -22.129575, states[40]= 0.000839
Saving checkpoint... 
Iteration: 586234934, states[0] = -86.438577, states[40]= 0.000001
Saving checkpoint... 
Iteration: 596174630, states[0] = -51.892341, states[40]= 0.000223
Saving checkpoint... 
Iteration: 606430056, states[0] = -86.960296, states[40]= 0.000002
Saving checkpoint... 
Iteration: 617445331, states[0] = -86.969070, states[40]= 0.000002
Saving checkpoint... 
Iteration: 628474322, states[0] = -86.982402, states[40]= 0.000002
Saving checkpoint... 
Iteration: 639514836, states[0] = 29.306905, states[40]= -0.000000
Saving checkpoint... 
Iteration: 649929155, states[0] = -86.956380, states[40]= 0.000002
Saving checkpoint... 
Iteration: 658820231, states[0] = -86.804609, states[40]= 0.000002
Saving checkpoint... 
Iteration: 667926452, states[0] = -86.953112, states[40]= 0.000002
Saving checkpoint... 
Iteration: 677388495, states[0] = -86.918383, states[40]= 0.000002
Saving checkpoint... 
Iteration: 687386971, states[0] = -86.915923, states[40]= 0.000002
Saving checkpoint... 
Iteration: 698225261, states[0] = -86.357620, states[40]= 0.000001
Saving checkpoint... 
Iteration: 708684955, states[0] = -64.225642, states[40]= 0.000043
Saving checkpoint... 
Iteration: 718107932, states[0] = 1.980265, states[40]= 0.000197
Saving checkpoint... 
Iteration: 727541229, states[0] = 29.077630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736911121, states[0] = -86.935904, states[40]= 0.000002
Saving checkpoint... 
Iteration: 745506995, states[0] = 23.701013, states[40]= -0.000000
Saving checkpoint... 
Iteration: 755290187, states[0] = -86.707877, states[40]= 0.000002
Saving checkpoint... 
Iteration: 765434062, states[0] = -86.951023, states[40]= 0.000002
Saving checkpoint... 
Iteration: 775384612, states[0] = -86.906639, states[40]= 0.000002
Saving checkpoint... 
Iteration: 786815261, states[0] = -86.782278, states[40]= 0.000002
Saving checkpoint... 
Iteration: 797680665, states[0] = -58.698780, states[40]= 0.000092
Saving checkpoint... 
Iteration: 808365399, states[0] = -86.879275, states[40]= 0.000002
Saving checkpoint... 
Iteration: 818845142, states[0] = -86.845491, states[40]= 0.000002
Saving checkpoint... 
Iteration: 829102721, states[0] = 4.806150, states[40]= 0.000126
Saving checkpoint... 
Iteration: 839702963, states[0] = -85.532661, states[40]= 0.000001
Saving checkpoint... 
Iteration: 850483495, states[0] = -86.969278, states[40]= 0.000002
Saving checkpoint... 
Iteration: 861426507, states[0] = -86.938575, states[40]= 0.000002
Saving checkpoint... 
Iteration: 872074058, states[0] = 18.136590, states[40]= 0.000006
Saving checkpoint... 
Iteration: 883038132, states[0] = 29.718968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892939548, states[0] = -86.944871, states[40]= 0.000002
Saving checkpoint... 
Iteration: 903318511, states[0] = -86.781718, states[40]= 0.000002
Saving checkpoint... 
Iteration: 913816249, states[0] = -86.775140, states[40]= 0.000002
Saving checkpoint... 
Iteration: 924314139, states[0] = -86.768810, states[40]= 0.000002
Saving checkpoint... 
Iteration: 935343091, states[0] = -86.832836, states[40]= 0.000002
Saving checkpoint... 
Iteration: 946195553, states[0] = -80.477802, states[40]= 0.000004
Saving checkpoint... 
Iteration: 957083274, states[0] = 14.162838, states[40]= 0.000017
Saving checkpoint... 
Iteration: 968068836, states[0] = 20.251710, states[40]= 0.000003
Saving checkpoint... 
Iteration: 978971774, states[0] = -86.955024, states[40]= 0.000002
Saving checkpoint... 
Iteration: 989911831, states[0] = -86.917479, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1000770584, states[0] = -86.610067, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1011510875, states[0] = 27.209986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022068988, states[0] = 20.193640, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1031133941, states[0] = -16.786589, states[40]= 0.000474
Saving checkpoint... 
Iteration: 1039867873, states[0] = -86.865271, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1048385261, states[0] = -86.886742, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1056736064, states[0] = -86.409834, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1065366545, states[0] = -86.861464, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1074383660, states[0] = -86.882915, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1083803126, states[0] = -86.725393, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1093526307, states[0] = 31.052350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103016933, states[0] = 30.021371, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1112406215, states[0] = -86.903303, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1121651287, states[0] = -30.121375, states[40]= 0.001400
Saving checkpoint... 
Iteration: 1131202173, states[0] = -85.298051, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1140907055, states[0] = -86.901966, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1151130256, states[0] = -13.751763, states[40]= 0.000428
Saving checkpoint... 
Iteration: 1162153657, states[0] = -32.023882, states[40]= 0.001347
Saving checkpoint... 
Iteration: 1173569406, states[0] = 20.033443, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1183697666, states[0] = -82.768640, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1194067949, states[0] = 20.606754, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1204195733, states[0] = -80.628549, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1214563018, states[0] = 22.479267, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1224934168, states[0] = -86.916479, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1234860289, states[0] = -86.839392, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1244500801, states[0] = 33.653638, states[40]= 0.942766
Saving checkpoint... 
Iteration: 1253425565, states[0] = -86.908387, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1261674848, states[0] = -52.016246, states[40]= 0.000217
Saving checkpoint... 
Iteration: 1269947460, states[0] = -86.921191, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1278652017, states[0] = -30.685659, states[40]= 0.001388
Saving checkpoint... 
Iteration: 1288044433, states[0] = 28.339834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298059631, states[0] = 23.701842, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1305174900, states[0] = -52.065701, states[40]= 0.000215
Saving checkpoint... 
Iteration: 1316644312, states[0] = -24.760333, states[40]= 0.001117
Saving checkpoint... 
Iteration: 1323755975, states[0] = -86.512237, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1335126135, states[0] = -10.355661, states[40]= 0.000423
Saving checkpoint... 
Iteration: 1346220121, states[0] = -86.264130, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1353209296, states[0] = -86.097040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363777969, states[0] = -86.614319, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1374299104, states[0] = -86.690726, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1384330344, states[0] = -86.772984, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1393778765, states[0] = -86.615304, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1403087519, states[0] = 12.252665, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1412263066, states[0] = -86.542538, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1421423439, states[0] = -86.894196, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1430954167, states[0] = -86.912732, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1440913453, states[0] = -86.884852, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1451280763, states[0] = -86.618999, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1461046614, states[0] = 27.779857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471583186, states[0] = 14.219939, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1482062441, states[0] = 22.699254, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1492492339, states[0] = -86.924149, states[40]= 0.000002
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.801883
 - CaMKt in component CaMK (millimolar): 0.027532
 - cass in component intracellular_ions (millimolar): 0.000097
 - nai in component intracellular_ions (millimolar): 8.240665
 - nass in component intracellular_ions (millimolar): 8.240829
 - ki in component intracellular_ions (millimolar): 142.960667
 - kss in component intracellular_ions (millimolar): 142.960626
 - cansr in component intracellular_ions (millimolar): 2.211805
 - cajsr in component intracellular_ions (millimolar): 2.156391
 - cai in component intracellular_ions (millimolar): 0.000100
 - m in component INa (dimensionless): 0.008183
 - hf in component INa (dimensionless): 0.659601
 - hs in component INa (dimensionless): 0.659572
 - j in component INa (dimensionless): 0.659404
 - hsp in component INa (dimensionless): 0.411532
 - jp in component INa (dimensionless): 0.659282
 - mL in component INaL (dimensionless): 0.000231
 - hL in component INaL (dimensionless): 0.455307
 - hLp in component INaL (dimensionless): 0.221004
 - a in component Ito (dimensionless): 0.001076
 - iF in component Ito (dimensionless): 0.999462
 - iS in component Ito (dimensionless): 0.530912
 - ap in component Ito (dimensionless): 0.000548
 - iFp in component Ito (dimensionless): 0.999462
 - iSp in component Ito (dimensionless): 0.574405
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.875731
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999602
 - jca in component ICaL (dimensionless): 0.999936
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004548
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.510038
 - xs1 in component IKs (dimensionless): 0.336586
 - xs2 in component IKs (dimensionless): 0.000218
 - xk1 in component IK1 (dimensionless): 0.997031
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
10:32:55 (6374): called boinc_finish(0)

</stderr_txt>
]]>


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