𝕏

Task 55212582

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-BASE_MID-conf_860_0
Workunit 26219890
Created 28 Jun 2024, 6:04:19 UTC
Sent 29 Jun 2024, 3:58:37 UTC
Report deadline 2 Jul 2024, 3:58:37 UTC
Received 29 Jun 2024, 7:38:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216894
Run time 2 hours 30 min 2 sec
CPU time 1 hours 55 min 27 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 4.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.93 MB
Peak swap size 32.60 GB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-BASE_MID-conf_860.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-BASE_MID-conf_860_0_r672371521_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-BASE_MID-conf_860_0_r672371521_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 110.549280
     * GNaL_b in INaL: 0.006710
     * Gto_b in Ito: 0.092226
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033758
     * GKs_b in IKs: 0.002069
     * GK1_b in IK1: 0.146812
     * Gncx_b in INaCa_i: 0.000959
     * Pnak_b in INaK: 69.866778
     * GKb_b in IKb: 0.003688
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.044234
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12653649, states[0] = -22.905067, states[40]= 0.000169
Saving checkpoint... 
Iteration: 25147014, states[0] = -21.975124, states[40]= 0.000235
Saving checkpoint... 
Iteration: 37557543, states[0] = 25.289006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49404092, states[0] = -86.779132, states[40]= 0.000002
Saving checkpoint... 
Iteration: 60609975, states[0] = 0.690548, states[40]= 0.000093
Saving checkpoint... 
Iteration: 72634422, states[0] = -19.221017, states[40]= 0.000214
Saving checkpoint... 
Iteration: 84741173, states[0] = -86.319370, states[40]= 0.000001
Saving checkpoint... 
Iteration: 95465025, states[0] = -86.880371, states[40]= 0.000002
Saving checkpoint... 
Iteration: 105577344, states[0] = 16.190365, states[40]= 0.000005
Saving checkpoint... 
Iteration: 116289534, states[0] = -86.598031, states[40]= 0.000001
Saving checkpoint... 
Iteration: 126919583, states[0] = -86.860777, states[40]= 0.000002
Saving checkpoint... 
Iteration: 137153833, states[0] = -38.141625, states[40]= 0.000345
Saving checkpoint... 
Iteration: 147692117, states[0] = -82.415248, states[40]= 0.000001
Saving checkpoint... 
Iteration: 158255412, states[0] = -86.436243, states[40]= 0.000001
Saving checkpoint... 
Iteration: 168841473, states[0] = -86.755906, states[40]= 0.000002
Saving checkpoint... 
Iteration: 179335617, states[0] = -86.743124, states[40]= 0.000002
Saving checkpoint... 
Iteration: 189612267, states[0] = -2.809688, states[40]= 0.000150
Saving checkpoint... 
Iteration: 200128857, states[0] = -16.751453, states[40]= 0.000193
Saving checkpoint... 
Iteration: 210695383, states[0] = -84.539040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221512347, states[0] = 28.276707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232244005, states[0] = -86.360788, states[40]= 0.000001
Saving checkpoint... 
Iteration: 242832986, states[0] = -86.734579, states[40]= 0.000002
Saving checkpoint... 
Iteration: 253203158, states[0] = -85.863264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263697439, states[0] = -85.174889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274304291, states[0] = -86.652988, states[40]= 0.000002
Saving checkpoint... 
Iteration: 284236990, states[0] = -86.307072, states[40]= 0.000001
Saving checkpoint... 
Iteration: 294937333, states[0] = -86.872207, states[40]= 0.000002
Saving checkpoint... 
Iteration: 305912045, states[0] = -86.851002, states[40]= 0.000002
Saving checkpoint... 
Iteration: 316445359, states[0] = -86.876254, states[40]= 0.000002
Saving checkpoint... 
Iteration: 327520095, states[0] = 30.710476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338491163, states[0] = -86.897584, states[40]= 0.000002
Saving checkpoint... 
Iteration: 349525239, states[0] = 31.009327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360081175, states[0] = 14.215527, states[40]= 0.000008
Saving checkpoint... 
Iteration: 370521813, states[0] = 30.893702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381085933, states[0] = 11.970341, states[40]= 0.000014
Saving checkpoint... 
Iteration: 391394202, states[0] = -86.827193, states[40]= 0.000002
Saving checkpoint... 
Iteration: 401576067, states[0] = 16.530777, states[40]= 0.000004
Saving checkpoint... 
Iteration: 411891732, states[0] = -86.823045, states[40]= 0.000002
Saving checkpoint... 
Iteration: 422109706, states[0] = -1.088176, states[40]= 0.000130
Saving checkpoint... 
Iteration: 432136754, states[0] = -23.568468, states[40]= 0.000351
Saving checkpoint... 
Iteration: 441871713, states[0] = -86.794714, states[40]= 0.000002
Saving checkpoint... 
Iteration: 451635631, states[0] = -22.629435, states[40]= 0.000317
Saving checkpoint... 
Iteration: 461279708, states[0] = -86.546698, states[40]= 0.000001
Saving checkpoint... 
Iteration: 470997515, states[0] = -86.891642, states[40]= 0.000002
Saving checkpoint... 
Iteration: 480665338, states[0] = -50.124977, states[40]= 0.000105


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-BASE_MID-conf_860.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-BASE_MID-conf_860_0_r672371521_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-BASE_MID-conf_860_0_r672371521_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 110.549280
     * GNaL_b in INaL: 0.006710
     * Gto_b in Ito: 0.092226
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033758
     * GKs_b in IKs: 0.002069
     * GK1_b in IK1: 0.146812
     * Gncx_b in INaCa_i: 0.000959
     * Pnak_b in INaK: 69.866778
     * GKb_b in IKb: 0.003688
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.044234
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 480665338
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -50.124977 (After loading)
 - states[40]: 0.000105 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 492531552, states[0] = 30.588631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503855716, states[0] = -86.764785, states[40]= 0.000002
Saving checkpoint... 
Iteration: 514104909, states[0] = 1.929896, states[40]= 0.000092
Saving checkpoint... 
Iteration: 523359997, states[0] = -86.771006, states[40]= 0.000002
Saving checkpoint... 
Iteration: 532588109, states[0] = 10.919360, states[40]= 0.000018
Saving checkpoint... 
Iteration: 541850813, states[0] = -86.753399, states[40]= 0.000002
Saving checkpoint... 
Iteration: 551079828, states[0] = 14.841646, states[40]= 0.000007
Saving checkpoint... 
Iteration: 561507991, states[0] = 24.962207, states[40]= -0.000000
Saving checkpoint... 
Iteration: 570630557, states[0] = -18.273229, states[40]= 0.000208
Saving checkpoint... 
Iteration: 580523152, states[0] = 30.980049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591259763, states[0] = -86.437391, states[40]= 0.000001
Saving checkpoint... 
Iteration: 602048416, states[0] = 26.938751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611830688, states[0] = -86.706139, states[40]= 0.000002
Saving checkpoint... 
Iteration: 622650841, states[0] = -35.715983, states[40]= 0.000409
Saving checkpoint... 
Iteration: 633555007, states[0] = 24.842981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644458644, states[0] = -86.863711, states[40]= 0.000002
Saving checkpoint... 
Iteration: 655155329, states[0] = -39.950417, states[40]= 0.000299
Saving checkpoint... 
Iteration: 666230245, states[0] = -86.229620, states[40]= 0.000001
Saving checkpoint... 
Iteration: 676097498, states[0] = 6.120590, states[40]= 0.000048
Saving checkpoint... 
Iteration: 685584843, states[0] = 12.501062, states[40]= 0.000013
Saving checkpoint... 
Iteration: 695212226, states[0] = -86.057723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705301465, states[0] = -86.616342, states[40]= 0.000002
Saving checkpoint... 
Iteration: 716114017, states[0] = -4.089070, states[40]= 0.000162
Saving checkpoint... 
Iteration: 727092003, states[0] = 8.986386, states[40]= 0.000027
Saving checkpoint... 
Iteration: 738014819, states[0] = 29.427426, states[40]= -0.000000
Saving checkpoint... 
Iteration: 749221403, states[0] = -86.148376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760138087, states[0] = -24.648044, states[40]= 0.000387
Saving checkpoint... 
Iteration: 771058638, states[0] = 23.573517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782144759, states[0] = -30.270833, states[40]= 0.000493
Saving checkpoint... 
Iteration: 793078977, states[0] = 15.236498, states[40]= 0.000006
Saving checkpoint... 
Iteration: 803905221, states[0] = -86.813285, states[40]= 0.000002
Saving checkpoint... 
Iteration: 813900926, states[0] = -86.808216, states[40]= 0.000002
Saving checkpoint... 
Iteration: 824032518, states[0] = 30.475241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834284381, states[0] = -86.543275, states[40]= 0.000001
Saving checkpoint... 
Iteration: 844615648, states[0] = -5.315263, states[40]= 0.000172
Saving checkpoint... 
Iteration: 854125534, states[0] = -13.758813, states[40]= 0.000182
Saving checkpoint... 
Iteration: 864514599, states[0] = 29.345422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875031324, states[0] = 30.625400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885480241, states[0] = -86.859214, states[40]= 0.000002
Saving checkpoint... 
Iteration: 896029278, states[0] = 30.831346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906402582, states[0] = -86.804183, states[40]= 0.000002
Saving checkpoint... 
Iteration: 916886111, states[0] = -86.784639, states[40]= 0.000002
Saving checkpoint... 
Iteration: 927239918, states[0] = -86.287266, states[40]= 0.000001
Saving checkpoint... 
Iteration: 937591975, states[0] = 9.007659, states[40]= 0.000027
Saving checkpoint... 
Iteration: 947980735, states[0] = -86.855521, states[40]= 0.000002
Saving checkpoint... 
Iteration: 957804470, states[0] = -86.610396, states[40]= 0.000002
Saving checkpoint... 
Iteration: 967889570, states[0] = -86.785754, states[40]= 0.000002
Saving checkpoint... 
Iteration: 977953370, states[0] = -86.839990, states[40]= 0.000002
Saving checkpoint... 
Iteration: 987895176, states[0] = -86.791062, states[40]= 0.000002
Saving checkpoint... 
Iteration: 997234020, states[0] = -86.238271, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1006602556, states[0] = 3.330372, states[40]= 0.000074
Saving checkpoint... 
Iteration: 1016300465, states[0] = -86.593212, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1026223065, states[0] = -86.145252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036716691, states[0] = -86.084756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047485006, states[0] = -86.851113, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1058521395, states[0] = 30.875177, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1069712904, states[0] = -86.041280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080410958, states[0] = -86.801654, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1090875259, states[0] = -86.759238, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1101249434, states[0] = -86.341633, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1111374896, states[0] = -86.757450, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1121188489, states[0] = -78.706836, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1131013536, states[0] = 28.897280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140765956, states[0] = -86.436369, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1151091145, states[0] = 9.433607, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1161762563, states[0] = -86.416622, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1172755730, states[0] = -86.376448, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1183794753, states[0] = -86.562120, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1194481594, states[0] = -86.840569, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1205235318, states[0] = -86.234859, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1215420106, states[0] = -86.801484, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1225225803, states[0] = -86.156261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235117930, states[0] = -7.102887, states[40]= 0.000180
Saving checkpoint... 
Iteration: 1244879355, states[0] = -86.755332, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1254393915, states[0] = -86.772980, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1262966565, states[0] = -86.829416, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1271367880, states[0] = -86.736972, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1280648357, states[0] = -33.392497, states[40]= 0.000455
Saving checkpoint... 
Iteration: 1289611566, states[0] = -2.296592, states[40]= 0.000142
Saving checkpoint... 
Iteration: 1299389627, states[0] = -86.765090, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1308485530, states[0] = -86.835110, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1318497680, states[0] = -86.839024, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1329342861, states[0] = -86.688223, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1340225956, states[0] = -86.150073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350895448, states[0] = -86.768708, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1361552157, states[0] = 25.803735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371900432, states[0] = -86.772897, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1382681970, states[0] = -69.498830, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1393257151, states[0] = -86.370820, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1403562286, states[0] = 22.237149, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1414111433, states[0] = -2.197123, states[40]= 0.000141
Saving checkpoint... 
Iteration: 1424911711, states[0] = -86.780906, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1435778544, states[0] = -86.479454, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1446233372, states[0] = -86.204115, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1455667718, states[0] = -52.523744, states[40]= 0.000077
Saving checkpoint... 
Iteration: 1465234415, states[0] = -86.211052, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1475436922, states[0] = -86.798447, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1485865912, states[0] = -86.720479, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1496465401, states[0] = -86.814325, states[40]= 0.000002
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.704447
 - CaMKt in component CaMK (millimolar): 0.025977
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 8.166191
 - nass in component intracellular_ions (millimolar): 8.166349
 - ki in component intracellular_ions (millimolar): 143.161622
 - kss in component intracellular_ions (millimolar): 143.161582
 - cansr in component intracellular_ions (millimolar): 2.117763
 - cajsr in component intracellular_ions (millimolar): 2.057510
 - cai in component intracellular_ions (millimolar): 0.000098
 - m in component INa (dimensionless): 0.008263
 - hf in component INa (dimensionless): 0.655997
 - hs in component INa (dimensionless): 0.655965
 - j in component INa (dimensionless): 0.655777
 - hsp in component INa (dimensionless): 0.407649
 - jp in component INa (dimensionless): 0.655641
 - mL in component INaL (dimensionless): 0.000235
 - hL in component INaL (dimensionless): 0.453114
 - hLp in component INaL (dimensionless): 0.220803
 - a in component Ito (dimensionless): 0.001083
 - iF in component Ito (dimensionless): 0.999452
 - iS in component Ito (dimensionless): 0.537648
 - ap in component Ito (dimensionless): 0.000552
 - iFp in component Ito (dimensionless): 0.999453
 - iSp in component Ito (dimensionless): 0.581257
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.881038
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999654
 - jca in component ICaL (dimensionless): 0.999945
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004135
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.505197
 - xs1 in component IKs (dimensionless): 0.327750
 - xs2 in component IKs (dimensionless): 0.000220
 - xk1 in component IK1 (dimensionless): 0.997054
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
23:35:10 (97762): called boinc_finish(0)

</stderr_txt>
]]>


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