𝕏

Task 55212577

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-BASE_MID-conf_460_1
Workunit 26219887
Created 28 Jun 2024, 6:04:19 UTC
Sent 29 Jun 2024, 3:58:37 UTC
Report deadline 2 Jul 2024, 3:58:37 UTC
Received 29 Jun 2024, 13:02:19 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216894
Run time 2 hours 31 min 56 sec
CPU time 1 hours 57 min 43 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 4.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.89 MB
Peak swap size 32.60 GB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-BASE_MID-conf_460.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-BASE_MID-conf_460_1_r655657865_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-BASE_MID-conf_460_1_r655657865_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 104.557588
     * GNaL_b in INaL: 0.006364
     * Gto_b in Ito: 0.085154
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033822
     * GKs_b in IKs: 0.001839
     * GK1_b in IK1: 0.150815
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 71.714367
     * GKb_b in IKb: 0.003864
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025980
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 7676337, states[0] = -39.498313, states[40]= 0.000124
Saving checkpoint... 
Iteration: 15210275, states[0] = -83.141969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25645434, states[0] = -20.610858, states[40]= 0.000168
Saving checkpoint... 
Iteration: 36237181, states[0] = -86.336172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46680223, states[0] = -57.556658, states[40]= 0.000026
Saving checkpoint... 
Iteration: 57423991, states[0] = -86.922194, states[40]= 0.000002
Saving checkpoint... 
Iteration: 68077120, states[0] = 16.891207, states[40]= 0.000003
Saving checkpoint... 
Iteration: 79066177, states[0] = 21.255650, states[40]= 0.000001
Saving checkpoint... 
Iteration: 89554306, states[0] = 25.514038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100049451, states[0] = 27.012162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110333634, states[0] = -86.833195, states[40]= 0.000002
Saving checkpoint... 
Iteration: 120770909, states[0] = -86.623230, states[40]= 0.000001
Saving checkpoint... 
Iteration: 130797390, states[0] = -86.734514, states[40]= 0.000001
Saving checkpoint... 
Iteration: 140673131, states[0] = -56.753405, states[40]= 0.000035
Saving checkpoint... 
Iteration: 150677234, states[0] = -61.693334, states[40]= 0.000018
Saving checkpoint... 
Iteration: 160534552, states[0] = 30.534171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170873383, states[0] = -86.911372, states[40]= 0.000002
Saving checkpoint... 
Iteration: 178310999, states[0] = -86.780474, states[40]= 0.000002
Saving checkpoint... 
Iteration: 183765910, states[0] = -86.601956, states[40]= 0.000001
Saving checkpoint... 
Iteration: 191578437, states[0] = 15.673149, states[40]= 0.000004
Saving checkpoint... 
Iteration: 203177460, states[0] = -62.254785, states[40]= 0.000017
Saving checkpoint... 
Iteration: 213975241, states[0] = -86.996874, states[40]= 0.000002
Saving checkpoint... 
Iteration: 224331470, states[0] = -86.832801, states[40]= 0.000002
Saving checkpoint... 
Iteration: 234345192, states[0] = -86.861765, states[40]= 0.000002
Saving checkpoint... 
Iteration: 244060279, states[0] = 23.141153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253801286, states[0] = -86.746926, states[40]= 0.000001
Saving checkpoint... 
Iteration: 263543833, states[0] = 28.463146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272916870, states[0] = -86.956459, states[40]= 0.000002
Saving checkpoint... 
Iteration: 283199944, states[0] = -85.672462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293399729, states[0] = -86.938785, states[40]= 0.000002
Saving checkpoint... 
Iteration: 303875499, states[0] = -86.908627, states[40]= 0.000002
Saving checkpoint... 
Iteration: 314563944, states[0] = 21.743976, states[40]= 0.000001
Saving checkpoint... 
Iteration: 324340895, states[0] = -86.848188, states[40]= 0.000002
Saving checkpoint... 
Iteration: 333786107, states[0] = -86.686799, states[40]= 0.000001
Saving checkpoint... 
Iteration: 343319206, states[0] = -86.795710, states[40]= 0.000002
Saving checkpoint... 
Iteration: 353136022, states[0] = -21.838831, states[40]= 0.000231
Saving checkpoint... 
Iteration: 363527217, states[0] = 31.398263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374165971, states[0] = -49.357347, states[40]= 0.000088
Saving checkpoint... 
Iteration: 384466121, states[0] = -86.983387, states[40]= 0.000002
Saving checkpoint... 
Iteration: 394385798, states[0] = -86.917084, states[40]= 0.000002
Saving checkpoint... 
Iteration: 404384312, states[0] = -86.914655, states[40]= 0.000002
Saving checkpoint... 
Iteration: 413749271, states[0] = -86.494597, states[40]= 0.000001
Saving checkpoint... 
Iteration: 423524623, states[0] = 31.492622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433707374, states[0] = -86.113983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444226952, states[0] = -86.331148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454718536, states[0] = -86.257426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465181394, states[0] = -67.451127, states[40]= 0.000008
Saving checkpoint... 
Iteration: 475805795, states[0] = -86.749037, states[40]= 0.000001
Saving checkpoint... 
Iteration: 486215014, states[0] = -86.221189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496480295, states[0] = -86.983682, states[40]= 0.000002
Saving checkpoint... 
Iteration: 506767010, states[0] = -86.590224, states[40]= 0.000001
Saving checkpoint... 
Iteration: 517112487, states[0] = -2.292103, states[40]= 0.000112
Saving checkpoint... 
Iteration: 525776223, states[0] = -86.633486, states[40]= 0.000001
Saving checkpoint... 
Iteration: 535532394, states[0] = 30.860914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546115974, states[0] = -4.762904, states[40]= 0.000131
Saving checkpoint... 
Iteration: 556254971, states[0] = -86.521211, states[40]= 0.000001
Saving checkpoint... 
Iteration: 566191676, states[0] = -81.721012, states[40]= 0.000001
Saving checkpoint... 
Iteration: 576018320, states[0] = 31.000608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585038446, states[0] = 29.768274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594742591, states[0] = -86.440049, states[40]= 0.000001
Saving checkpoint... 
Iteration: 605235933, states[0] = -86.391900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615742356, states[0] = -86.437205, states[40]= 0.000001
Saving checkpoint... 
Iteration: 626442034, states[0] = -86.955836, states[40]= 0.000002
Saving checkpoint... 
Iteration: 637054902, states[0] = 25.073387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648016023, states[0] = 30.455206, states[40]= -0.000000
Saving checkpoint... 
Iteration: 658794115, states[0] = -86.698862, states[40]= 0.000001
Saving checkpoint... 
Iteration: 668847199, states[0] = -86.841285, states[40]= 0.000002
Saving checkpoint... 
Iteration: 679134476, states[0] = -20.510225, states[40]= 0.000200
Saving checkpoint... 
Iteration: 689169706, states[0] = -53.320432, states[40]= 0.000054
Saving checkpoint... 
Iteration: 699211011, states[0] = -86.161483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709679304, states[0] = -64.589750, states[40]= 0.000012
Saving checkpoint... 
Iteration: 720089846, states[0] = 10.332021, states[40]= 0.000015
Saving checkpoint... 
Iteration: 730320524, states[0] = -86.777205, states[40]= 0.000002
Saving checkpoint... 
Iteration: 740556116, states[0] = 24.654614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750708032, states[0] = -86.108721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760942166, states[0] = -86.948349, states[40]= 0.000002
Saving checkpoint... 
Iteration: 771032666, states[0] = 30.827022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780932583, states[0] = -86.940533, states[40]= 0.000002
Saving checkpoint... 
Iteration: 790602985, states[0] = 3.515668, states[40]= 0.000055
Saving checkpoint... 
Iteration: 800392938, states[0] = -86.902709, states[40]= 0.000002
Saving checkpoint... 
Iteration: 810302723, states[0] = -86.720040, states[40]= 0.000001
Saving checkpoint... 
Iteration: 820820273, states[0] = -86.771401, states[40]= 0.000002
Saving checkpoint... 
Iteration: 831567552, states[0] = 20.321214, states[40]= 0.000001
Saving checkpoint... 
Iteration: 841632603, states[0] = -18.892645, states[40]= 0.000173
Saving checkpoint... 
Iteration: 851494912, states[0] = -86.969492, states[40]= 0.000002
Saving checkpoint... 
Iteration: 861392724, states[0] = -86.899012, states[40]= 0.000002
Saving checkpoint... 
Iteration: 871663130, states[0] = -46.335239, states[40]= 0.000122
Saving checkpoint... 
Iteration: 881442835, states[0] = -86.942014, states[40]= 0.000002
Saving checkpoint... 
Iteration: 890583663, states[0] = 13.284052, states[40]= 0.000008
Saving checkpoint... 
Iteration: 899642434, states[0] = -27.110991, states[40]= 0.000362
Saving checkpoint... 
Iteration: 908309593, states[0] = -86.736091, states[40]= 0.000002
Saving checkpoint... 
Iteration: 916944198, states[0] = -86.940928, states[40]= 0.000002
Saving checkpoint... 
Iteration: 926566162, states[0] = 20.882603, states[40]= 0.000001
Saving checkpoint... 
Iteration: 937010062, states[0] = 27.467455, states[40]= -0.000000
Saving checkpoint... 
Iteration: 947551332, states[0] = 26.267852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958370498, states[0] = -86.864461, states[40]= 0.000002
Saving checkpoint... 
Iteration: 969315259, states[0] = -86.749192, states[40]= 0.000002
Saving checkpoint... 
Iteration: 980135058, states[0] = -20.977545, states[40]= 0.000209
Saving checkpoint... 
Iteration: 990513498, states[0] = 29.525342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999873082, states[0] = -86.865873, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1010563875, states[0] = 21.786302, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1021201804, states[0] = -85.819726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031978399, states[0] = -86.952807, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1042781462, states[0] = -86.626906, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1053429586, states[0] = -86.922976, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1063565996, states[0] = 20.951980, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1074059683, states[0] = 23.378266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084521429, states[0] = 31.407913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094803609, states[0] = -86.706689, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1105294289, states[0] = -86.673968, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1115956557, states[0] = -86.937189, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1126657560, states[0] = -40.715731, states[40]= 0.000213
Saving checkpoint... 
Iteration: 1137545632, states[0] = 27.990905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147436673, states[0] = -86.922894, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1157258811, states[0] = -86.508683, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1166444898, states[0] = -86.927356, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1176470409, states[0] = -86.941015, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1186851013, states[0] = -86.819193, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1197277757, states[0] = -86.601842, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1207415057, states[0] = -86.902278, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1217968357, states[0] = -86.937678, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1228732720, states[0] = -86.331203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239746375, states[0] = -86.427983, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1250527412, states[0] = 31.406458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261281154, states[0] = -86.613072, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1272085954, states[0] = 12.218160, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1282856677, states[0] = -86.823937, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1293279822, states[0] = -86.605458, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1302706038, states[0] = -86.024183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311600461, states[0] = 4.921036, states[40]= 0.000044
Saving checkpoint... 
Iteration: 1321555038, states[0] = 25.042065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332221396, states[0] = -86.231749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342839112, states[0] = -86.786674, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1353543195, states[0] = 28.654803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363958503, states[0] = -86.924378, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1374458384, states[0] = -86.923718, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1385296991, states[0] = -86.667694, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1396192808, states[0] = -82.594710, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1406020890, states[0] = 31.370301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416958770, states[0] = -86.921533, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1427892723, states[0] = -86.867091, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1438879026, states[0] = -86.849379, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1448639739, states[0] = -24.830200, states[40]= 0.000308
Saving checkpoint... 
Iteration: 1458679329, states[0] = -64.485474, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1468988533, states[0] = -86.932491, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1479318436, states[0] = -86.729025, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1486743907, states[0] = -86.397199, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1496826601, states[0] = -86.749227, states[40]= 0.000002
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.810796
 - CaMKt in component CaMK (millimolar): 0.025118
 - cass in component intracellular_ions (millimolar): 0.000093
 - nai in component intracellular_ions (millimolar): 8.029797
 - nass in component intracellular_ions (millimolar): 8.029950
 - ki in component intracellular_ions (millimolar): 143.356319
 - kss in component intracellular_ions (millimolar): 143.356279
 - cansr in component intracellular_ions (millimolar): 2.055832
 - cajsr in component intracellular_ions (millimolar): 1.991349
 - cai in component intracellular_ions (millimolar): 0.000096
 - m in component INa (dimensionless): 0.008176
 - hf in component INa (dimensionless): 0.659930
 - hs in component INa (dimensionless): 0.659897
 - j in component INa (dimensionless): 0.659709
 - hsp in component INa (dimensionless): 0.411874
 - jp in component INa (dimensionless): 0.659574
 - mL in component INaL (dimensionless): 0.000231
 - hL in component INaL (dimensionless): 0.456403
 - hLp in component INaL (dimensionless): 0.222845
 - a in component Ito (dimensionless): 0.001076
 - iF in component Ito (dimensionless): 0.999463
 - iS in component Ito (dimensionless): 0.537002
 - ap in component Ito (dimensionless): 0.000548
 - iFp in component Ito (dimensionless): 0.999463
 - iSp in component Ito (dimensionless): 0.580783
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.879351
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999638
 - jca in component ICaL (dimensionless): 0.999943
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003882
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.505927
 - xs1 in component IKs (dimensionless): 0.330265
 - xs2 in component IKs (dimensionless): 0.000217
 - xk1 in component IK1 (dimensionless): 0.997029
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
05:04:15 (2080): called boinc_finish(0)

</stderr_txt>
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