𝕏

Task 55212525

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-TESZT_Block_Kr_70-conf_59_1
Workunit 26219861
Created 28 Jun 2024, 6:04:19 UTC
Sent 29 Jun 2024, 3:58:37 UTC
Report deadline 2 Jul 2024, 3:58:37 UTC
Received 29 Jun 2024, 13:02:19 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216894
Run time 2 hours 32 min 55 sec
CPU time 1 hours 57 min 46 sec
Validate state Valid
Credit 43.01
Device peak FLOPS 4.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.82 MB
Peak swap size 32.60 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-TESZT_Block_Kr_70-conf_59.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-TESZT_Block_Kr_70-conf_59_1_r2107239065_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-TESZT_Block_Kr_70-conf_59_1_r2107239065_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 106.033344
     * GNaL_b in INaL: 0.007196
     * Gto_b in Ito: 0.079253
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.008923
     * GKs_b in IKs: 0.002022
     * GK1_b in IK1: 0.157918
     * Gncx_b in INaCa_i: 0.000959
     * Pnak_b in INaK: 68.802019
     * GKb_b in IKb: 0.003718
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037194
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 3914383, states[0] = -94.839344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 11819399, states[0] = -94.646839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23236088, states[0] = -42.358387, states[40]= 0.000793
Saving checkpoint... 
Iteration: 33991742, states[0] = -94.712904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44270086, states[0] = -52.886226, states[40]= 0.000155
Saving checkpoint... 
Iteration: 54230803, states[0] = -36.502154, states[40]= 0.001771
Saving checkpoint... 
Iteration: 63943351, states[0] = -94.653289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73651473, states[0] = -12.018474, states[40]= 0.002730
Saving checkpoint... 
Iteration: 83316049, states[0] = -81.824146, states[40]= 0.000001
Saving checkpoint... 
Iteration: 92800930, states[0] = -64.831276, states[40]= 0.000018
Saving checkpoint... 
Iteration: 103132614, states[0] = -3.736683, states[40]= 0.004093
Saving checkpoint... 
Iteration: 113232562, states[0] = -35.070606, states[40]= 0.002039
Saving checkpoint... 
Iteration: 123703979, states[0] = -26.941269, states[40]= 0.004663
Saving checkpoint... 
Iteration: 134258523, states[0] = -43.623295, states[40]= 0.000632
Saving checkpoint... 
Iteration: 143923770, states[0] = -94.612492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153465731, states[0] = -94.638092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162945528, states[0] = -94.625929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172794406, states[0] = -58.619282, states[40]= 0.000053
Saving checkpoint... 
Iteration: 183263063, states[0] = -44.958212, states[40]= 0.000514
Saving checkpoint... 
Iteration: 193804932, states[0] = -64.794632, states[40]= 0.000018
Saving checkpoint... 
Iteration: 204081480, states[0] = 14.586210, states[40]= 0.005089
Saving checkpoint... 
Iteration: 214043179, states[0] = 26.221281, states[40]= 0.003646
Saving checkpoint... 
Iteration: 224009463, states[0] = 31.941676, states[40]= 0.053961
Saving checkpoint... 
Iteration: 233271368, states[0] = -48.062432, states[40]= 0.000316
Saving checkpoint... 
Iteration: 243163453, states[0] = -15.637757, states[40]= 0.003279
Saving checkpoint... 
Iteration: 253394509, states[0] = -94.581160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263843001, states[0] = -94.431248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274366808, states[0] = -94.547357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284831436, states[0] = -92.484817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295420160, states[0] = -94.604614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305774973, states[0] = -49.470000, states[40]= 0.000251
Saving checkpoint... 
Iteration: 316027401, states[0] = 30.488342, states[40]= 0.003354
Saving checkpoint... 
Iteration: 326291325, states[0] = -56.718063, states[40]= 0.000073
Saving checkpoint... 
Iteration: 336248197, states[0] = -39.460378, states[40]= 0.001133
Saving checkpoint... 
Iteration: 345098745, states[0] = 8.856795, states[40]= 0.005195
Saving checkpoint... 
Iteration: 354973703, states[0] = -94.637832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365584521, states[0] = 13.612709, states[40]= 0.005128
Saving checkpoint... 
Iteration: 375496197, states[0] = -94.647239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385679652, states[0] = -20.520133, states[40]= 0.005337
Saving checkpoint... 
Iteration: 395223607, states[0] = -31.801378, states[40]= 0.002960
Saving checkpoint... 
Iteration: 404312409, states[0] = -70.521179, states[40]= 0.000007
Saving checkpoint... 
Iteration: 413989984, states[0] = -94.644744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424632866, states[0] = -3.415971, states[40]= 0.004122
Saving checkpoint... 
Iteration: 435069447, states[0] = 18.424774, states[40]= 0.004813
Saving checkpoint... 
Iteration: 445701705, states[0] = -26.032167, states[40]= 0.004903
Saving checkpoint... 
Iteration: 456243254, states[0] = -37.806389, states[40]= 0.001415
Saving checkpoint... 
Iteration: 467168700, states[0] = -17.372043, states[40]= 0.004067
Saving checkpoint... 
Iteration: 477929808, states[0] = -94.611542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487913093, states[0] = -94.598127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498122517, states[0] = 0.507753, states[40]= 0.004741
Saving checkpoint... 
Iteration: 508113564, states[0] = 3.729279, states[40]= 0.005031
Saving checkpoint... 
Iteration: 518216958, states[0] = -29.957277, states[40]= 0.003593
Saving checkpoint... 
Iteration: 528694973, states[0] = -24.379839, states[40]= 0.005275
Saving checkpoint... 
Iteration: 538937937, states[0] = -94.617145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549105137, states[0] = 6.669081, states[40]= 0.005160
Saving checkpoint... 
Iteration: 559389197, states[0] = -94.574385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569472122, states[0] = -94.636604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579662144, states[0] = -15.151256, states[40]= 0.003116
Saving checkpoint... 
Iteration: 589674368, states[0] = -19.068819, states[40]= 0.004897
Saving checkpoint... 
Iteration: 599577462, states[0] = 15.902284, states[40]= 0.005017
Saving checkpoint... 
Iteration: 609208016, states[0] = -27.613087, states[40]= 0.004416
Saving checkpoint... 
Iteration: 619020589, states[0] = 31.725748, states[40]= 0.004483
Saving checkpoint... 
Iteration: 628897617, states[0] = -94.583214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639448445, states[0] = -94.623674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650137415, states[0] = -5.223008, states[40]= 0.003757
Saving checkpoint... 
Iteration: 660131562, states[0] = -2.906789, states[40]= 0.004218
Saving checkpoint... 
Iteration: 669919082, states[0] = -94.602814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679881523, states[0] = -94.565273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690144130, states[0] = -7.967486, states[40]= 0.003196
Saving checkpoint... 
Iteration: 699772451, states[0] = -48.433972, states[40]= 0.000297
Saving checkpoint... 
Iteration: 708928883, states[0] = -94.610379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717910628, states[0] = -94.595472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726598679, states[0] = 8.880445, states[40]= 0.005195
Saving checkpoint... 
Iteration: 735207023, states[0] = -27.360872, states[40]= 0.004500
Saving checkpoint... 
Iteration: 745123224, states[0] = 0.247710, states[40]= 0.004709
Saving checkpoint... 
Iteration: 755552326, states[0] = 23.559059, states[40]= 0.004087
Saving checkpoint... 
Iteration: 766091487, states[0] = 11.305553, states[40]= 0.005186
Saving checkpoint... 
Iteration: 776945169, states[0] = -94.621366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787912787, states[0] = -94.597237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798693398, states[0] = -23.993952, states[40]= 0.005336
Saving checkpoint... 
Iteration: 808910285, states[0] = -94.594977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818421314, states[0] = -94.604316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829071782, states[0] = 17.699070, states[40]= 0.004882
Saving checkpoint... 
Iteration: 839705790, states[0] = -27.049651, states[40]= 0.004600
Saving checkpoint... 
Iteration: 850492059, states[0] = -94.644653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861272982, states[0] = -48.647560, states[40]= 0.000287
Saving checkpoint... 
Iteration: 871810120, states[0] = -68.456017, states[40]= 0.000010
Saving checkpoint... 
Iteration: 882071428, states[0] = 17.809644, states[40]= 0.004872
Saving checkpoint... 
Iteration: 892587228, states[0] = 12.721873, states[40]= 0.005156
Saving checkpoint... 
Iteration: 902973173, states[0] = -94.636414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913209850, states[0] = -28.082340, states[40]= 0.004256
Saving checkpoint... 
Iteration: 923615217, states[0] = 3.143899, states[40]= 0.004991
Saving checkpoint... 
Iteration: 934332725, states[0] = -93.033083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945015258, states[0] = 32.098837, states[40]= 0.010735
Saving checkpoint... 
Iteration: 955846418, states[0] = -94.484396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965521415, states[0] = 31.614055, states[40]= 0.004174
Saving checkpoint... 
Iteration: 975256787, states[0] = -42.463937, states[40]= 0.000742
Saving checkpoint... 
Iteration: 984500047, states[0] = -88.844084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994529719, states[0] = 29.944368, states[40]= 0.003311
Saving checkpoint... 
Iteration: 1004975666, states[0] = -94.637368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015082925, states[0] = 14.136012, states[40]= 0.005108
Saving checkpoint... 
Iteration: 1025485338, states[0] = -94.641574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036050207, states[0] = 24.180629, states[40]= 0.003982
Saving checkpoint... 
Iteration: 1046808675, states[0] = -67.263183, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1057842573, states[0] = -94.415544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068568518, states[0] = 18.712035, states[40]= 0.004783
Saving checkpoint... 
Iteration: 1079335874, states[0] = -93.876264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090067887, states[0] = 18.906201, states[40]= 0.004762
Saving checkpoint... 
Iteration: 1100710019, states[0] = -28.125714, states[40]= 0.004241
Saving checkpoint... 
Iteration: 1111001420, states[0] = 49.771064, states[40]= 0.192002
Saving checkpoint... 
Iteration: 1120275227, states[0] = -49.560582, states[40]= 0.000247
Saving checkpoint... 
Iteration: 1129384034, states[0] = -94.567315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139409317, states[0] = -94.593419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150112147, states[0] = 4.229269, states[40]= 0.005061
Saving checkpoint... 
Iteration: 1160697251, states[0] = -24.936710, states[40]= 0.005169
Saving checkpoint... 
Iteration: 1171231908, states[0] = -34.232801, states[40]= 0.002229
Saving checkpoint... 
Iteration: 1181773341, states[0] = -48.792036, states[40]= 0.000280
Saving checkpoint... 
Iteration: 1192269943, states[0] = -47.433713, states[40]= 0.000348
Saving checkpoint... 
Iteration: 1203079143, states[0] = 15.362900, states[40]= 0.005049
Saving checkpoint... 
Iteration: 1213862269, states[0] = -94.538568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223714866, states[0] = -29.395173, states[40]= 0.003793
Saving checkpoint... 
Iteration: 1234703775, states[0] = -26.544962, states[40]= 0.004756
Saving checkpoint... 
Iteration: 1245601392, states[0] = 7.955789, states[40]= 0.005186
Saving checkpoint... 
Iteration: 1256484743, states[0] = -94.640847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266027830, states[0] = 30.392718, states[40]= 0.003341
Saving checkpoint... 
Iteration: 1276119077, states[0] = 1.761495, states[40]= 0.004875
Saving checkpoint... 
Iteration: 1286531254, states[0] = 29.559849, states[40]= 0.003312
Saving checkpoint... 
Iteration: 1296851001, states[0] = -94.513614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304333316, states[0] = -93.244011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314244482, states[0] = -38.209550, states[40]= 0.001341
Saving checkpoint... 
Iteration: 1321235507, states[0] = -35.334389, states[40]= 0.001946
Saving checkpoint... 
Iteration: 1331541201, states[0] = 26.807274, states[40]= 0.003570
Saving checkpoint... 
Iteration: 1338391458, states[0] = -94.575254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345706881, states[0] = -27.324429, states[40]= 0.004512
Saving checkpoint... 
Iteration: 1355667522, states[0] = -16.994035, states[40]= 0.003875
Saving checkpoint... 
Iteration: 1365414625, states[0] = -94.597634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375110376, states[0] = 4.850490, states[40]= 0.005093
Saving checkpoint... 
Iteration: 1385037401, states[0] = 27.894143, states[40]= 0.003436
Saving checkpoint... 
Iteration: 1394837510, states[0] = -94.105919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404811418, states[0] = -69.592028, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1415417242, states[0] = -94.599747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425869747, states[0] = -94.548755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436155048, states[0] = -12.441930, states[40]= 0.002707
Saving checkpoint... 
Iteration: 1446378404, states[0] = -94.559886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456349440, states[0] = -94.506128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466259439, states[0] = -43.429416, states[40]= 0.000644
Saving checkpoint... 
Iteration: 1476140859, states[0] = -6.620876, states[40]= 0.003465
Saving checkpoint... 
Iteration: 1485999193, states[0] = -94.646030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496041715, states[0] = 26.658708, states[40]= 0.003590
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.522170
 - CaMKt in component CaMK (millimolar): 0.015793
 - cass in component intracellular_ions (millimolar): 0.000083
 - nai in component intracellular_ions (millimolar): 6.275491
 - nass in component intracellular_ions (millimolar): 6.275566
 - ki in component intracellular_ions (millimolar): 145.647011
 - kss in component intracellular_ions (millimolar): 145.647004
 - cansr in component intracellular_ions (millimolar): 1.542933
 - cajsr in component intracellular_ions (millimolar): 1.466209
 - cai in component intracellular_ions (millimolar): 0.000085
 - m in component INa (dimensionless): 0.003760
 - hf in component INa (dimensionless): 0.873255
 - hs in component INa (dimensionless): 0.873240
 - j in component INa (dimensionless): 0.873140
 - hsp in component INa (dimensionless): 0.713182
 - jp in component INa (dimensionless): 0.872890
 - mL in component INaL (dimensionless): 0.000053
 - hL in component INaL (dimensionless): 0.601560
 - hLp in component INaL (dimensionless): 0.288365
 - a in component Ito (dimensionless): 0.000640
 - iF in component Ito (dimensionless): 0.999861
 - iS in component Ito (dimensionless): 0.435357
 - ap in component Ito (dimensionless): 0.000326
 - iFp in component Ito (dimensionless): 0.999861
 - iSp in component Ito (dimensionless): 0.482601
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.835944
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.998702
 - jca in component ICaL (dimensionless): 0.999771
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002568
 - xrf in component IKr (dimensionless): 0.000016
 - xrs in component IKr (dimensionless): 0.560953
 - xs1 in component IKs (dimensionless): 0.378881
 - xs2 in component IKs (dimensionless): 0.000092
 - xk1 in component IK1 (dimensionless): 0.997436
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:24:33 (2413): called boinc_finish(0)

</stderr_txt>
]]>


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