𝕏

Task 55212428

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_666-conf_459_0
Workunit 26219813
Created 28 Jun 2024, 6:04:14 UTC
Sent 29 Jun 2024, 3:58:37 UTC
Report deadline 2 Jul 2024, 3:58:41 UTC
Received 29 Jun 2024, 7:38:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216894
Run time 2 hours 30 min 41 sec
CPU time 1 hours 55 min 58 sec
Validate state Valid
Credit 42.74
Device peak FLOPS 4.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.86 MB
Peak swap size 32.60 GB
Peak disk usage 0.23 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_666-conf_459.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_666-conf_459_0_r1838221068_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_666-conf_459_0_r1838221068_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000150.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 116.212951
     * GNaL_b in INaL: 0.005031
     * Gto_b in Ito: 0.074426
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030220
     * GKs_b in IKs: 0.001817
     * GK1_b in IK1: 0.178066
     * Gncx_b in INaCa_i: 0.000959
     * Pnak_b in INaK: 68.256735
     * GKb_b in IKb: 0.003746
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.018862
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4500.000000
     * CL_0 in membrane: 666.700000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499741650.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12476645, states[0] = -64.268971, states[40]= 0.000008
Saving checkpoint... 
Iteration: 24794047, states[0] = -44.259257, states[40]= 0.000106
Saving checkpoint... 
Iteration: 37044456, states[0] = 22.616159, states[40]= 0.000016
Saving checkpoint... 
Iteration: 48691530, states[0] = 30.923480, states[40]= 0.000770
Saving checkpoint... 
Iteration: 59714479, states[0] = 21.509121, states[40]= 0.000019
Saving checkpoint... 
Iteration: 71549529, states[0] = -84.369353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83471170, states[0] = -52.860340, states[40]= 0.000034
Saving checkpoint... 
Iteration: 94008454, states[0] = 33.516426, states[40]= 0.566606
Saving checkpoint... 
Iteration: 103956470, states[0] = -84.654769, states[40]= 0.000001
Saving checkpoint... 
Iteration: 114533468, states[0] = -84.250382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124988849, states[0] = -84.717802, states[40]= 0.000001
Saving checkpoint... 
Iteration: 135037352, states[0] = 27.926147, states[40]= 0.000047
Saving checkpoint... 
Iteration: 145390452, states[0] = 18.976718, states[40]= 0.000030
Saving checkpoint... 
Iteration: 155803004, states[0] = -47.420763, states[40]= 0.000067
Saving checkpoint... 
Iteration: 166242351, states[0] = -84.483217, states[40]= 0.000001
Saving checkpoint... 
Iteration: 176582429, states[0] = -84.510442, states[40]= 0.000001
Saving checkpoint... 
Iteration: 186705238, states[0] = 28.475277, states[40]= 0.000073
Saving checkpoint... 
Iteration: 197046811, states[0] = 25.165309, states[40]= 0.000013
Saving checkpoint... 
Iteration: 207448753, states[0] = -22.660004, states[40]= 0.000301
Saving checkpoint... 
Iteration: 218054520, states[0] = 22.049038, states[40]= 0.000016
Saving checkpoint... 
Iteration: 228616007, states[0] = -84.618042, states[40]= 0.000001
Saving checkpoint... 
Iteration: 239009592, states[0] = -84.738506, states[40]= 0.000001
Saving checkpoint... 
Iteration: 249204086, states[0] = -84.227453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259492181, states[0] = -68.016182, states[40]= 0.000004
Saving checkpoint... 
Iteration: 269913656, states[0] = -84.478575, states[40]= 0.000001
Saving checkpoint... 
Iteration: 279652388, states[0] = -84.695872, states[40]= 0.000001
Saving checkpoint... 
Iteration: 290126196, states[0] = -29.731701, states[40]= 0.000294
Saving checkpoint... 
Iteration: 300895820, states[0] = -84.376589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311260507, states[0] = -84.526713, states[40]= 0.000001
Saving checkpoint... 
Iteration: 322224040, states[0] = -84.338605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332984595, states[0] = -84.687391, states[40]= 0.000001
Saving checkpoint... 
Iteration: 343801266, states[0] = -35.725838, states[40]= 0.000215
Saving checkpoint... 
Iteration: 354200581, states[0] = -84.155178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364464161, states[0] = -30.693887, states[40]= 0.000287
Saving checkpoint... 
Iteration: 374817008, states[0] = -50.717835, states[40]= 0.000045
Saving checkpoint... 
Iteration: 384942428, states[0] = -84.568100, states[40]= 0.000001
Saving checkpoint... 
Iteration: 394976635, states[0] = -84.662693, states[40]= 0.000001
Saving checkpoint... 
Iteration: 405165379, states[0] = -66.970224, states[40]= 0.000005
Saving checkpoint... 
Iteration: 415228965, states[0] = -84.338046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425074266, states[0] = 17.366251, states[40]= 0.000041
Saving checkpoint... 
Iteration: 434639266, states[0] = -84.647581, states[40]= 0.000001
Saving checkpoint... 
Iteration: 444232771, states[0] = -84.351999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453713866, states[0] = 30.217204, states[40]= 0.000370
Saving checkpoint... 
Iteration: 463282532, states[0] = -84.576112, states[40]= 0.000001
Saving checkpoint... 
Iteration: 472811556, states[0] = -39.720069, states[40]= 0.000152


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_666-conf_459.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_666-conf_459_0_r1838221068_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_666-conf_459_0_r1838221068_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000150.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 116.212951
     * GNaL_b in INaL: 0.005031
     * Gto_b in Ito: 0.074426
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030220
     * GKs_b in IKs: 0.001817
     * GK1_b in IK1: 0.178066
     * Gncx_b in INaCa_i: 0.000959
     * Pnak_b in INaK: 68.256735
     * GKb_b in IKb: 0.003746
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.018862
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4500.000000
     * CL_0 in membrane: 666.700000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499741650.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 472811556
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -39.720069 (After loading)
 - states[40]: 0.000152 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 484739650, states[0] = 19.529591, states[40]= 0.000027
Saving checkpoint... 
Iteration: 496083430, states[0] = 14.422571, states[40]= 0.000067
Saving checkpoint... 
Iteration: 506310138, states[0] = -84.647493, states[40]= 0.000001
Saving checkpoint... 
Iteration: 515580427, states[0] = -84.412150, states[40]= 0.000001
Saving checkpoint... 
Iteration: 524818403, states[0] = -44.176632, states[40]= 0.000096
Saving checkpoint... 
Iteration: 534093597, states[0] = 9.849646, states[40]= 0.000137
Saving checkpoint... 
Iteration: 543357631, states[0] = -84.731101, states[40]= 0.000001
Saving checkpoint... 
Iteration: 553825534, states[0] = -50.244574, states[40]= 0.000047
Saving checkpoint... 
Iteration: 562960809, states[0] = -84.595062, states[40]= 0.000001
Saving checkpoint... 
Iteration: 572887411, states[0] = -84.223689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583687059, states[0] = -84.721696, states[40]= 0.000001
Saving checkpoint... 
Iteration: 594453522, states[0] = -6.890997, states[40]= 0.000487
Saving checkpoint... 
Iteration: 604240540, states[0] = -84.347104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615069564, states[0] = 24.322253, states[40]= 0.000012
Saving checkpoint... 
Iteration: 625989733, states[0] = -84.661083, states[40]= 0.000001
Saving checkpoint... 
Iteration: 636910682, states[0] = -84.357232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647634494, states[0] = -84.601585, states[40]= 0.000001
Saving checkpoint... 
Iteration: 658684911, states[0] = -84.710963, states[40]= 0.000001
Saving checkpoint... 
Iteration: 668566913, states[0] = -84.279081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678061443, states[0] = 29.136427, states[40]= 0.000130
Saving checkpoint... 
Iteration: 687682596, states[0] = -84.704194, states[40]= 0.000001
Saving checkpoint... 
Iteration: 697820791, states[0] = -37.614824, states[40]= 0.000185
Saving checkpoint... 
Iteration: 708644275, states[0] = -84.619155, states[40]= 0.000001
Saving checkpoint... 
Iteration: 719602679, states[0] = -84.467680, states[40]= 0.000001
Saving checkpoint... 
Iteration: 730551226, states[0] = -84.133243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741745079, states[0] = 23.144990, states[40]= 0.000014
Saving checkpoint... 
Iteration: 752690377, states[0] = -84.710033, states[40]= 0.000001
Saving checkpoint... 
Iteration: 763650189, states[0] = -84.626323, states[40]= 0.000001
Saving checkpoint... 
Iteration: 774718985, states[0] = 32.224434, states[40]= 0.017654
Saving checkpoint... 
Iteration: 785677580, states[0] = -84.684328, states[40]= 0.000001
Saving checkpoint... 
Iteration: 796521966, states[0] = -72.093164, states[40]= 0.000002
Saving checkpoint... 
Iteration: 806541805, states[0] = -83.892224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816659545, states[0] = -84.641984, states[40]= 0.000001
Saving checkpoint... 
Iteration: 826937289, states[0] = -84.445863, states[40]= 0.000001
Saving checkpoint... 
Iteration: 837321233, states[0] = -84.626443, states[40]= 0.000001
Saving checkpoint... 
Iteration: 846844037, states[0] = -54.495986, states[40]= 0.000028
Saving checkpoint... 
Iteration: 857272824, states[0] = -84.448330, states[40]= 0.000001
Saving checkpoint... 
Iteration: 867792856, states[0] = -0.331193, states[40]= 0.000411
Saving checkpoint... 
Iteration: 878262121, states[0] = -84.386891, states[40]= 0.000001
Saving checkpoint... 
Iteration: 888796268, states[0] = -2.168230, states[40]= 0.000450
Saving checkpoint... 
Iteration: 899159634, states[0] = -32.850234, states[40]= 0.000260
Saving checkpoint... 
Iteration: 909613555, states[0] = -84.469753, states[40]= 0.000001
Saving checkpoint... 
Iteration: 919977518, states[0] = -84.583473, states[40]= 0.000001
Saving checkpoint... 
Iteration: 930286508, states[0] = -84.492415, states[40]= 0.000001
Saving checkpoint... 
Iteration: 940697283, states[0] = -84.701852, states[40]= 0.000001
Saving checkpoint... 
Iteration: 950552979, states[0] = -84.011315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960591238, states[0] = -84.335817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970664319, states[0] = -84.631305, states[40]= 0.000001
Saving checkpoint... 
Iteration: 980570328, states[0] = -84.182214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989927926, states[0] = -84.346909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999288224, states[0] = -84.483455, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1008997840, states[0] = -84.626093, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1018934247, states[0] = -84.374599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029453358, states[0] = 8.895173, states[40]= 0.000157
Saving checkpoint... 
Iteration: 1040224790, states[0] = -84.022554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051271267, states[0] = -84.385813, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1062467806, states[0] = 0.738282, states[40]= 0.000379
Saving checkpoint... 
Iteration: 1073163283, states[0] = -27.525880, states[40]= 0.000304
Saving checkpoint... 
Iteration: 1083703760, states[0] = -84.697705, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1094000090, states[0] = -84.619182, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1104094179, states[0] = 24.250439, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1113914109, states[0] = -84.208754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123755551, states[0] = 27.051219, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1133460612, states[0] = 7.688662, states[40]= 0.000183
Saving checkpoint... 
Iteration: 1143813441, states[0] = -6.031499, states[40]= 0.000490
Saving checkpoint... 
Iteration: 1154485336, states[0] = -10.784357, states[40]= 0.000439
Saving checkpoint... 
Iteration: 1165483407, states[0] = -8.198766, states[40]= 0.000477
Saving checkpoint... 
Iteration: 1176561164, states[0] = -83.918875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187232563, states[0] = -84.026902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197994595, states[0] = -84.587031, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1208201247, states[0] = -61.332522, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1217984945, states[0] = -84.552539, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1227895925, states[0] = -83.868365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237678026, states[0] = -84.626291, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1247206699, states[0] = -65.859553, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1255796844, states[0] = 9.572751, states[40]= 0.000142
Saving checkpoint... 
Iteration: 1264215533, states[0] = -76.755521, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1273477641, states[0] = 1.251484, states[40]= 0.000364
Saving checkpoint... 
Iteration: 1282489923, states[0] = -8.873860, states[40]= 0.000465
Saving checkpoint... 
Iteration: 1292273543, states[0] = -84.322784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301378982, states[0] = -84.688999, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1311396221, states[0] = -84.714349, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1322239730, states[0] = -84.030734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333039822, states[0] = -84.675195, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1343697690, states[0] = -84.656564, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1354326211, states[0] = -84.553091, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1364677010, states[0] = -84.604439, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1375421937, states[0] = 31.561211, states[40]= 0.001922
Saving checkpoint... 
Iteration: 1386074651, states[0] = 31.454227, states[40]= 0.325706
Saving checkpoint... 
Iteration: 1396423281, states[0] = 31.493678, states[40]= 0.001732
Saving checkpoint... 
Iteration: 1407033697, states[0] = -84.654091, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1417755593, states[0] = 31.916958, states[40]= 0.003626
Saving checkpoint... 
Iteration: 1428664303, states[0] = -84.554907, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1439117475, states[0] = 21.133330, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1448580842, states[0] = -84.049261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458162093, states[0] = -5.647773, states[40]= 0.000489
Saving checkpoint... 
Iteration: 1468348413, states[0] = -84.600728, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1478836783, states[0] = -12.830502, states[40]= 0.000399
Saving checkpoint... 
Iteration: 1489430694, states[0] = 30.745040, states[40]= 0.000654
Saving checkpoint... 
Iteration: 1493533609, states[0] = -44.247660, states[40]= 0.000095
Total time: 3000150.000000
State Variables:
 - v in component membrane (millivolt): -84.589463
 - CaMKt in component CaMK (millimolar): 0.039664
 - cass in component intracellular_ions (millimolar): 0.000105
 - nai in component intracellular_ions (millimolar): 6.845944
 - nass in component intracellular_ions (millimolar): 6.846100
 - ki in component intracellular_ions (millimolar): 144.809424
 - kss in component intracellular_ions (millimolar): 144.809398
 - cansr in component intracellular_ions (millimolar): 2.098603
 - cajsr in component intracellular_ions (millimolar): 1.860491
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.010218
 - hf in component INa (dimensionless): 0.573951
 - hs in component INa (dimensionless): 0.573808
 - j in component INa (dimensionless): 0.573026
 - hsp in component INa (dimensionless): 0.326808
 - jp in component INa (dimensionless): 0.572367
 - mL in component INaL (dimensionless): 0.000352
 - hL in component INaL (dimensionless): 0.346036
 - hLp in component INaL (dimensionless): 0.150422
 - a in component Ito (dimensionless): 0.001250
 - iF in component Ito (dimensionless): 0.999207
 - iS in component Ito (dimensionless): 0.362148
 - ap in component Ito (dimensionless): 0.000637
 - iFp in component Ito (dimensionless): 0.999207
 - iSp in component Ito (dimensionless): 0.395797
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.838860
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.995406
 - jca in component ICaL (dimensionless): 0.998001
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.006218
 - xrf in component IKr (dimensionless): 0.000441
 - xrs in component IKr (dimensionless): 0.679219
 - xs1 in component IKs (dimensionless): 0.391203
 - xs2 in component IKs (dimensionless): 0.000280
 - xk1 in component IK1 (dimensionless): 0.996779
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
23:36:09 (97761): called boinc_finish(0)

</stderr_txt>
]]>


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