𝕏

Task 55212426

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_666-conf_359_0
Workunit 26219812
Created 28 Jun 2024, 6:04:14 UTC
Sent 29 Jun 2024, 3:58:37 UTC
Report deadline 2 Jul 2024, 3:58:41 UTC
Received 29 Jun 2024, 7:38:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216894
Run time 2 hours 31 min 1 sec
CPU time 1 hours 56 min 16 sec
Validate state Valid
Credit 42.50
Device peak FLOPS 4.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.96 MB
Peak swap size 32.60 GB
Peak disk usage 0.23 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_666-conf_359.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_666-conf_359_0_r1024061364_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_666-conf_359_0_r1024061364_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000150.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.995683
     * GNaL_b in INaL: 0.006206
     * Gto_b in Ito: 0.087984
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030489
     * GKs_b in IKs: 0.002098
     * GK1_b in IK1: 0.151475
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 66.178258
     * GKb_b in IKb: 0.003926
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032332
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4500.000000
     * CL_0 in membrane: 666.700000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499741650.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11682739, states[0] = 31.486857, states[40]= 0.008032
Saving checkpoint... 
Iteration: 23998730, states[0] = -84.579823, states[40]= 0.000001
Saving checkpoint... 
Iteration: 36232377, states[0] = -84.264663, states[40]= 0.000001
Saving checkpoint... 
Iteration: 47876630, states[0] = -84.120714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58924656, states[0] = -84.395855, states[40]= 0.000001
Saving checkpoint... 
Iteration: 70806491, states[0] = -55.579387, states[40]= 0.000016
Saving checkpoint... 
Iteration: 82742504, states[0] = 6.684293, states[40]= 0.000113
Saving checkpoint... 
Iteration: 93276914, states[0] = -84.468084, states[40]= 0.000001
Saving checkpoint... 
Iteration: 103241254, states[0] = -84.315503, states[40]= 0.000001
Saving checkpoint... 
Iteration: 113816261, states[0] = -64.257960, states[40]= 0.000005
Saving checkpoint... 
Iteration: 124269249, states[0] = -84.437270, states[40]= 0.000001
Saving checkpoint... 
Iteration: 134356456, states[0] = 31.409454, states[40]= 0.006406
Saving checkpoint... 
Iteration: 144734853, states[0] = 12.845823, states[40]= 0.000044
Saving checkpoint... 
Iteration: 155141335, states[0] = -53.059874, states[40]= 0.000021
Saving checkpoint... 
Iteration: 165584001, states[0] = -84.348917, states[40]= 0.000001
Saving checkpoint... 
Iteration: 175930204, states[0] = -84.404559, states[40]= 0.000001
Saving checkpoint... 
Iteration: 186043218, states[0] = 26.141459, states[40]= 0.000016
Saving checkpoint... 
Iteration: 196373314, states[0] = 27.686659, states[40]= 0.000050
Saving checkpoint... 
Iteration: 206772368, states[0] = -12.940121, states[40]= 0.000226
Saving checkpoint... 
Iteration: 217356041, states[0] = 31.095376, states[40]= 0.032804
Saving checkpoint... 
Iteration: 227944743, states[0] = -84.449794, states[40]= 0.000001
Saving checkpoint... 
Iteration: 238374522, states[0] = 28.031016, states[40]= 0.000068
Saving checkpoint... 
Iteration: 248619692, states[0] = -84.474215, states[40]= 0.000001
Saving checkpoint... 
Iteration: 258934552, states[0] = -84.403654, states[40]= 0.000001
Saving checkpoint... 
Iteration: 269366206, states[0] = 31.025792, states[40]= 0.002198
Saving checkpoint... 
Iteration: 279093224, states[0] = 1.657284, states[40]= 0.000191
Saving checkpoint... 
Iteration: 289638116, states[0] = -84.521544, states[40]= 0.000001
Saving checkpoint... 
Iteration: 300413188, states[0] = 10.665135, states[40]= 0.000063
Saving checkpoint... 
Iteration: 310763369, states[0] = 0.288978, states[40]= 0.000213
Saving checkpoint... 
Iteration: 321657398, states[0] = -84.563091, states[40]= 0.000001
Saving checkpoint... 
Iteration: 332397199, states[0] = 19.969894, states[40]= 0.000012
Saving checkpoint... 
Iteration: 343229014, states[0] = -84.163052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353572366, states[0] = -84.226795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363820139, states[0] = -54.865855, states[40]= 0.000017
Saving checkpoint... 
Iteration: 374266823, states[0] = -84.371104, states[40]= 0.000001
Saving checkpoint... 
Iteration: 384400810, states[0] = 19.471023, states[40]= 0.000013
Saving checkpoint... 
Iteration: 394450045, states[0] = -14.737342, states[40]= 0.000207
Saving checkpoint... 
Iteration: 404629867, states[0] = -84.477988, states[40]= 0.000001
Saving checkpoint... 
Iteration: 414719796, states[0] = 26.781810, states[40]= 0.000024
Saving checkpoint... 
Iteration: 424587218, states[0] = -84.292054, states[40]= 0.000001
Saving checkpoint... 
Iteration: 434175367, states[0] = -75.828171, states[40]= 0.000001
Saving checkpoint... 
Iteration: 443769248, states[0] = 0.857013, states[40]= 0.000204
Saving checkpoint... 
Iteration: 453274974, states[0] = -84.387910, states[40]= 0.000001
Saving checkpoint... 
Iteration: 462851040, states[0] = -81.651863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472363918, states[0] = 29.580690, states[40]= 0.186766


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_666-conf_359.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_666-conf_359_0_r1024061364_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_666-conf_359_0_r1024061364_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000150.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.995683
     * GNaL_b in INaL: 0.006206
     * Gto_b in Ito: 0.087984
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030489
     * GKs_b in IKs: 0.002098
     * GK1_b in IK1: 0.151475
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 66.178258
     * GKb_b in IKb: 0.003926
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032332
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4500.000000
     * CL_0 in membrane: 666.700000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499741650.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 472363918
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 29.580690 (After loading)
 - states[40]: 0.186766 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 484261584, states[0] = -84.316136, states[40]= 0.000001
Saving checkpoint... 
Iteration: 495487293, states[0] = -48.511708, states[40]= 0.000037
Saving checkpoint... 
Iteration: 505682374, states[0] = -84.589186, states[40]= 0.000001
Saving checkpoint... 
Iteration: 514966660, states[0] = -84.468892, states[40]= 0.000001
Saving checkpoint... 
Iteration: 524167842, states[0] = -61.749038, states[40]= 0.000007
Saving checkpoint... 
Iteration: 533388112, states[0] = 28.472201, states[40]= 0.000101
Saving checkpoint... 
Iteration: 542583278, states[0] = -84.231363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552976509, states[0] = -84.492674, states[40]= 0.000001
Saving checkpoint... 
Iteration: 562059512, states[0] = 27.188774, states[40]= 0.000033
Saving checkpoint... 
Iteration: 571940165, states[0] = -84.351395, states[40]= 0.000001
Saving checkpoint... 
Iteration: 582683077, states[0] = -84.581817, states[40]= 0.000001
Saving checkpoint... 
Iteration: 593436974, states[0] = 5.198582, states[40]= 0.000131
Saving checkpoint... 
Iteration: 603195400, states[0] = -82.893628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613986787, states[0] = -84.511499, states[40]= 0.000001
Saving checkpoint... 
Iteration: 624863890, states[0] = -83.032865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635650589, states[0] = -84.500090, states[40]= 0.000001
Saving checkpoint... 
Iteration: 646336458, states[0] = -84.546937, states[40]= 0.000001
Saving checkpoint... 
Iteration: 657391876, states[0] = 29.335836, states[40]= 0.000238
Saving checkpoint... 
Iteration: 667271639, states[0] = -84.316385, states[40]= 0.000001
Saving checkpoint... 
Iteration: 676734961, states[0] = 25.913993, states[40]= 0.000013
Saving checkpoint... 
Iteration: 686341677, states[0] = -84.552999, states[40]= 0.000001
Saving checkpoint... 
Iteration: 696447799, states[0] = 1.398925, states[40]= 0.000195
Saving checkpoint... 
Iteration: 707176050, states[0] = -60.687621, states[40]= 0.000008
Saving checkpoint... 
Iteration: 718097678, states[0] = 12.387714, states[40]= 0.000048
Saving checkpoint... 
Iteration: 728956079, states[0] = -84.383955, states[40]= 0.000001
Saving checkpoint... 
Iteration: 740123197, states[0] = -3.728107, states[40]= 0.000262
Saving checkpoint... 
Iteration: 750961201, states[0] = -84.400182, states[40]= 0.000001
Saving checkpoint... 
Iteration: 761914059, states[0] = -84.134182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772917694, states[0] = -84.156196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783832778, states[0] = -46.162975, states[40]= 0.000049
Saving checkpoint... 
Iteration: 794627304, states[0] = -84.387817, states[40]= 0.000001
Saving checkpoint... 
Iteration: 804611642, states[0] = -84.312037, states[40]= 0.000001
Saving checkpoint... 
Iteration: 814723986, states[0] = 31.397077, states[40]= 0.006004
Saving checkpoint... 
Iteration: 824979085, states[0] = -84.451178, states[40]= 0.000001
Saving checkpoint... 
Iteration: 835296140, states[0] = -84.387421, states[40]= 0.000001
Saving checkpoint... 
Iteration: 844793891, states[0] = -2.698793, states[40]= 0.000253
Saving checkpoint... 
Iteration: 855183688, states[0] = -60.944600, states[40]= 0.000007
Saving checkpoint... 
Iteration: 865678898, states[0] = -84.537341, states[40]= 0.000001
Saving checkpoint... 
Iteration: 876093062, states[0] = 18.975815, states[40]= 0.000014
Saving checkpoint... 
Iteration: 886565336, states[0] = -83.949519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896903761, states[0] = -83.992584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907362279, states[0] = -84.567017, states[40]= 0.000001
Saving checkpoint... 
Iteration: 917694372, states[0] = -84.563469, states[40]= 0.000001
Saving checkpoint... 
Iteration: 927980239, states[0] = -84.434806, states[40]= 0.000001
Saving checkpoint... 
Iteration: 938314086, states[0] = -84.434552, states[40]= 0.000001
Saving checkpoint... 
Iteration: 948114615, states[0] = 9.304865, states[40]= 0.000077
Saving checkpoint... 
Iteration: 958131583, states[0] = -1.629060, states[40]= 0.000241
Saving checkpoint... 
Iteration: 968161944, states[0] = -32.452785, states[40]= 0.000162
Saving checkpoint... 
Iteration: 978054437, states[0] = 29.532483, states[40]= 0.309136
Saving checkpoint... 
Iteration: 987360321, states[0] = -84.553287, states[40]= 0.000001
Saving checkpoint... 
Iteration: 996713194, states[0] = -84.588107, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1006419884, states[0] = 25.142174, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1016315342, states[0] = -84.423076, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1026789886, states[0] = 6.509991, states[40]= 0.000113
Saving checkpoint... 
Iteration: 1037536361, states[0] = -72.938807, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1048493335, states[0] = -26.239749, states[40]= 0.000184
Saving checkpoint... 
Iteration: 1059663015, states[0] = -84.463741, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1070314269, states[0] = -84.407624, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1080834070, states[0] = -32.267473, states[40]= 0.000162
Saving checkpoint... 
Iteration: 1091140205, states[0] = -3.254168, states[40]= 0.000259
Saving checkpoint... 
Iteration: 1101213687, states[0] = -80.189594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110988319, states[0] = -84.426521, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1120795257, states[0] = 6.096485, states[40]= 0.000118
Saving checkpoint... 
Iteration: 1130514403, states[0] = -43.724524, states[40]= 0.000064
Saving checkpoint... 
Iteration: 1140822484, states[0] = -16.704057, states[40]= 0.000190
Saving checkpoint... 
Iteration: 1151442936, states[0] = 17.574131, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1162373564, states[0] = -84.558279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1173382220, states[0] = -84.573005, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1184013317, states[0] = -84.492578, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1194747613, states[0] = 30.646263, states[40]= 0.001155
Saving checkpoint... 
Iteration: 1204903724, states[0] = -83.788211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214681936, states[0] = -84.493004, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1224544251, states[0] = -71.186514, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1234317947, states[0] = -84.385466, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1243776935, states[0] = 19.564664, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1252325081, states[0] = -84.409820, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1260729598, states[0] = -84.587038, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1269966426, states[0] = -84.291345, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1278931206, states[0] = -84.054591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288689164, states[0] = -84.500581, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1297721231, states[0] = -84.569039, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1307669984, states[0] = -84.439892, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1318446369, states[0] = 20.045531, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1329234648, states[0] = -83.319149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339857853, states[0] = -43.357230, states[40]= 0.000066
Saving checkpoint... 
Iteration: 1350468005, states[0] = 9.343751, states[40]= 0.000077
Saving checkpoint... 
Iteration: 1360785765, states[0] = 18.073396, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1371538128, states[0] = -55.815325, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1382095202, states[0] = 29.198802, states[40]= 0.000205
Saving checkpoint... 
Iteration: 1392396387, states[0] = -84.573252, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1402978083, states[0] = -84.313685, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1413721397, states[0] = -84.555854, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1424526593, states[0] = -41.142979, states[40]= 0.000083
Saving checkpoint... 
Iteration: 1434904628, states[0] = -83.043153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444289443, states[0] = -84.173180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453824603, states[0] = -2.903890, states[40]= 0.000255
Saving checkpoint... 
Iteration: 1464005516, states[0] = -84.416355, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1474454618, states[0] = 19.824260, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1485031585, states[0] = -84.493893, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1489127343, states[0] = 17.138607, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1496572612, states[0] = -82.681414, states[40]= 0.000000
Total time: 3000150.000000
State Variables:
 - v in component membrane (millivolt): -84.457155
 - CaMKt in component CaMK (millimolar): 0.040301
 - cass in component intracellular_ions (millimolar): 0.000104
 - nai in component intracellular_ions (millimolar): 6.949045
 - nass in component intracellular_ions (millimolar): 6.949200
 - ki in component intracellular_ions (millimolar): 144.698986
 - kss in component intracellular_ions (millimolar): 144.698959
 - cansr in component intracellular_ions (millimolar): 2.079514
 - cajsr in component intracellular_ions (millimolar): 1.828935
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.010354
 - hf in component INa (dimensionless): 0.568626
 - hs in component INa (dimensionless): 0.568457
 - j in component INa (dimensionless): 0.567538
 - hsp in component INa (dimensionless): 0.321970
 - jp in component INa (dimensionless): 0.566770
 - mL in component INaL (dimensionless): 0.000360
 - hL in component INaL (dimensionless): 0.340095
 - hLp in component INaL (dimensionless): 0.146433
 - a in component Ito (dimensionless): 0.001261
 - iF in component Ito (dimensionless): 0.999188
 - iS in component Ito (dimensionless): 0.360935
 - ap in component Ito (dimensionless): 0.000642
 - iFp in component Ito (dimensionless): 0.999188
 - iSp in component Ito (dimensionless): 0.394101
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.841385
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.995631
 - jca in component ICaL (dimensionless): 0.998049
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005986
 - xrf in component IKr (dimensionless): 0.000480
 - xrs in component IKr (dimensionless): 0.678261
 - xs1 in component IKs (dimensionless): 0.388079
 - xs2 in component IKs (dimensionless): 0.000284
 - xk1 in component IK1 (dimensionless): 0.996812
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
23:36:53 (97764): called boinc_finish(0)

</stderr_txt>
]]>


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