𝕏

Task 55212424

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_575-conf_959_0
Workunit 26219811
Created 28 Jun 2024, 6:04:14 UTC
Sent 29 Jun 2024, 3:58:37 UTC
Report deadline 2 Jul 2024, 3:58:47 UTC
Received 29 Jun 2024, 15:36:56 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216894
Run time 2 hours 32 min 32 sec
CPU time 1 hours 57 min 50 sec
Validate state Valid
Credit 42.81
Device peak FLOPS 4.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.96 MB
Peak swap size 32.60 GB
Peak disk usage 0.20 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_575-conf_959.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_575-conf_959_0_r66918083_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_575-conf_959_0_r66918083_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000350.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 107.482244
     * GNaL_b in INaL: 0.004460
     * Gto_b in Ito: 0.080129
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030205
     * GKs_b in IKs: 0.001774
     * GK1_b in IK1: 0.163227
     * Gncx_b in INaCa_i: 0.000959
     * Pnak_b in INaK: 66.006675
     * GKb_b in IKb: 0.003711
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.052266
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 5218.000000
     * CL_0 in membrane: 575.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499887500.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 5424010, states[0] = -84.624287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 15445573, states[0] = -84.335203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24961944, states[0] = -84.472528, states[40]= 0.000001
Saving checkpoint... 
Iteration: 34674152, states[0] = -84.052192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44454177, states[0] = -84.114098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54205140, states[0] = -82.377671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63873868, states[0] = 18.495718, states[40]= 0.000016
Saving checkpoint... 
Iteration: 74309781, states[0] = -61.085034, states[40]= 0.000009
Saving checkpoint... 
Iteration: 84664809, states[0] = -67.523231, states[40]= 0.000004
Saving checkpoint... 
Iteration: 94952013, states[0] = 1.113858, states[40]= 0.000217
Saving checkpoint... 
Iteration: 105047148, states[0] = -33.718423, states[40]= 0.000168
Saving checkpoint... 
Iteration: 114844129, states[0] = -57.775881, states[40]= 0.000014
Saving checkpoint... 
Iteration: 124833405, states[0] = 13.125044, states[40]= 0.000042
Saving checkpoint... 
Iteration: 134555775, states[0] = 30.247228, states[40]= 0.290559
Saving checkpoint... 
Iteration: 144283722, states[0] = -84.551182, states[40]= 0.000001
Saving checkpoint... 
Iteration: 154242777, states[0] = -71.812994, states[40]= 0.000002
Saving checkpoint... 
Iteration: 161247306, states[0] = -84.555271, states[40]= 0.000001
Saving checkpoint... 
Iteration: 168613988, states[0] = -66.850137, states[40]= 0.000004
Saving checkpoint... 
Iteration: 175941031, states[0] = -84.650648, states[40]= 0.000001
Saving checkpoint... 
Iteration: 186817168, states[0] = -84.479997, states[40]= 0.000001
Saving checkpoint... 
Iteration: 196612014, states[0] = -84.562858, states[40]= 0.000001
Saving checkpoint... 
Iteration: 207162850, states[0] = -83.815119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217344565, states[0] = -84.658242, states[40]= 0.000001
Saving checkpoint... 
Iteration: 227047928, states[0] = -84.374079, states[40]= 0.000001
Saving checkpoint... 
Iteration: 236600643, states[0] = -84.641998, states[40]= 0.000001
Saving checkpoint... 
Iteration: 245780181, states[0] = -84.581471, states[40]= 0.000001
Saving checkpoint... 
Iteration: 254299417, states[0] = -79.474235, states[40]= 0.000001
Saving checkpoint... 
Iteration: 263721781, states[0] = -5.292517, states[40]= 0.000291
Saving checkpoint... 
Iteration: 273993375, states[0] = 30.219225, states[40]= 0.280619
Saving checkpoint... 
Iteration: 284682172, states[0] = 13.811124, states[40]= 0.000037
Saving checkpoint... 
Iteration: 295497617, states[0] = -84.502200, states[40]= 0.000001
Saving checkpoint... 
Iteration: 306241331, states[0] = 15.684072, states[40]= 0.000026
Saving checkpoint... 
Iteration: 316319084, states[0] = 6.590453, states[40]= 0.000115
Saving checkpoint... 
Iteration: 326068158, states[0] = 21.317283, states[40]= 0.000008
Saving checkpoint... 
Iteration: 335376999, states[0] = -81.321406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344539362, states[0] = -38.985821, states[40]= 0.000114
Saving checkpoint... 
Iteration: 353752664, states[0] = -53.424867, states[40]= 0.000024
Saving checkpoint... 
Iteration: 363385002, states[0] = -84.630191, states[40]= 0.000001
Saving checkpoint... 
Iteration: 373195771, states[0] = 30.771425, states[40]= 0.001362
Saving checkpoint... 
Iteration: 383170736, states[0] = -84.429176, states[40]= 0.000001
Saving checkpoint... 
Iteration: 393434760, states[0] = -61.577452, states[40]= 0.000009
Saving checkpoint... 
Iteration: 403766171, states[0] = -40.936750, states[40]= 0.000096
Saving checkpoint... 
Iteration: 414134118, states[0] = -60.806395, states[40]= 0.000009
Saving checkpoint... 
Iteration: 424451768, states[0] = -25.112503, states[40]= 0.000196
Saving checkpoint... 
Iteration: 434971307, states[0] = -84.624912, states[40]= 0.000001
Saving checkpoint... 
Iteration: 445215406, states[0] = -83.916103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455624532, states[0] = -84.447021, states[40]= 0.000001
Saving checkpoint... 
Iteration: 465764201, states[0] = 31.663231, states[40]= 0.014276
Saving checkpoint... 
Iteration: 475792656, states[0] = -84.613584, states[40]= 0.000001
Saving checkpoint... 
Iteration: 485090218, states[0] = 0.470542, states[40]= 0.000223
Saving checkpoint... 
Iteration: 495011124, states[0] = -84.441189, states[40]= 0.000001
Saving checkpoint... 
Iteration: 504938831, states[0] = -10.105908, states[40]= 0.000276
Saving checkpoint... 
Iteration: 515238129, states[0] = 23.797685, states[40]= 0.000007
Saving checkpoint... 
Iteration: 525622423, states[0] = 4.354637, states[40]= 0.000152
Saving checkpoint... 
Iteration: 535653466, states[0] = 22.414595, states[40]= 0.000007
Saving checkpoint... 
Iteration: 545174217, states[0] = 3.092947, states[40]= 0.000175
Saving checkpoint... 
Iteration: 554648259, states[0] = 11.739175, states[40]= 0.000053
Saving checkpoint... 
Iteration: 564029107, states[0] = -84.521968, states[40]= 0.000001
Saving checkpoint... 
Iteration: 573407286, states[0] = -58.640848, states[40]= 0.000013
Saving checkpoint... 
Iteration: 582739241, states[0] = -84.600537, states[40]= 0.000001
Saving checkpoint... 
Iteration: 592092185, states[0] = -55.667958, states[40]= 0.000018
Saving checkpoint... 
Iteration: 601450363, states[0] = -38.755079, states[40]= 0.000023
Saving checkpoint... 
Iteration: 611230008, states[0] = 30.603027, states[40]= 0.380216
Saving checkpoint... 
Iteration: 620480151, states[0] = 14.955102, states[40]= 0.000030
Saving checkpoint... 
Iteration: 629317505, states[0] = -84.608723, states[40]= 0.000001
Saving checkpoint... 
Iteration: 638770615, states[0] = -84.483214, states[40]= 0.000001
Saving checkpoint... 
Iteration: 649134072, states[0] = -84.539001, states[40]= 0.000001
Saving checkpoint... 
Iteration: 660209160, states[0] = -33.314002, states[40]= 0.000169
Saving checkpoint... 
Iteration: 671119979, states[0] = -17.263552, states[40]= 0.000207
Saving checkpoint... 
Iteration: 681942372, states[0] = -84.639742, states[40]= 0.000001
Saving checkpoint... 
Iteration: 692818932, states[0] = -84.473873, states[40]= 0.000001
Saving checkpoint... 
Iteration: 703326239, states[0] = -24.501454, states[40]= 0.000195
Saving checkpoint... 
Iteration: 713885095, states[0] = 30.256092, states[40]= 0.000712
Saving checkpoint... 
Iteration: 724543304, states[0] = 21.248441, states[40]= 0.000008
Saving checkpoint... 
Iteration: 735111878, states[0] = -84.588967, states[40]= 0.000001
Saving checkpoint... 
Iteration: 745763281, states[0] = -84.627732, states[40]= 0.000001
Saving checkpoint... 
Iteration: 756595299, states[0] = -84.153964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767118463, states[0] = 7.001570, states[40]= 0.000109
Saving checkpoint... 
Iteration: 777161006, states[0] = 18.563445, states[40]= 0.000014
Saving checkpoint... 
Iteration: 788092624, states[0] = 14.972423, states[40]= 0.000030
Saving checkpoint... 
Iteration: 798993331, states[0] = 27.141971, states[40]= 0.000040
Saving checkpoint... 
Iteration: 809652871, states[0] = 16.218371, states[40]= 0.000023
Saving checkpoint... 
Iteration: 820399347, states[0] = -83.732961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830105814, states[0] = -15.293745, states[40]= 0.000223
Saving checkpoint... 
Iteration: 839444952, states[0] = -84.474334, states[40]= 0.000001
Saving checkpoint... 
Iteration: 849770351, states[0] = -84.339669, states[40]= 0.000001
Saving checkpoint... 
Iteration: 860267376, states[0] = 7.700229, states[40]= 0.000099
Saving checkpoint... 
Iteration: 870399124, states[0] = -63.821535, states[40]= 0.000006
Saving checkpoint... 
Iteration: 880098948, states[0] = 11.336845, states[40]= 0.000057
Saving checkpoint... 
Iteration: 889597064, states[0] = 4.608854, states[40]= 0.000148
Saving checkpoint... 
Iteration: 899545425, states[0] = -84.527349, states[40]= 0.000001
Saving checkpoint... 
Iteration: 909795868, states[0] = -75.707745, states[40]= 0.000001
Saving checkpoint... 
Iteration: 919397207, states[0] = -84.576846, states[40]= 0.000001
Saving checkpoint... 
Iteration: 930030399, states[0] = -84.562447, states[40]= 0.000001
Saving checkpoint... 
Iteration: 941008174, states[0] = 30.803012, states[40]= 0.001410
Saving checkpoint... 
Iteration: 951783921, states[0] = -83.444536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962493079, states[0] = -84.462012, states[40]= 0.000001
Saving checkpoint... 
Iteration: 972987724, states[0] = -8.856823, states[40]= 0.000285
Saving checkpoint... 
Iteration: 983483447, states[0] = -84.474693, states[40]= 0.000001
Saving checkpoint... 
Iteration: 994043571, states[0] = -82.908692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004370963, states[0] = -59.988137, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1014698816, states[0] = -35.651362, states[40]= 0.000147
Saving checkpoint... 
Iteration: 1024841159, states[0] = -84.215568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035416110, states[0] = -54.436298, states[40]= 0.000022
Saving checkpoint... 
Iteration: 1046107322, states[0] = -84.141141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056199382, states[0] = -84.358755, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1066138873, states[0] = -10.130322, states[40]= 0.000275
Saving checkpoint... 
Iteration: 1076424552, states[0] = 29.617688, states[40]= 0.000356
Saving checkpoint... 
Iteration: 1087235213, states[0] = -84.263392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097708247, states[0] = 26.080933, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1108298368, states[0] = -84.611012, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1118662246, states[0] = -84.644162, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1127891146, states[0] = 28.062374, states[40]= 0.000084
Saving checkpoint... 
Iteration: 1138252268, states[0] = 23.010857, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1149142562, states[0] = 30.562535, states[40]= 0.372962
Saving checkpoint... 
Iteration: 1160135257, states[0] = 4.135758, states[40]= 0.000156
Saving checkpoint... 
Iteration: 1171050043, states[0] = 10.688189, states[40]= 0.000063
Saving checkpoint... 
Iteration: 1181946384, states[0] = 25.793647, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1192721754, states[0] = -84.025489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203470424, states[0] = -84.631961, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1214230329, states[0] = -42.685258, states[40]= 0.000081
Saving checkpoint... 
Iteration: 1223944352, states[0] = 14.005693, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1234794800, states[0] = -84.597707, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1245701643, states[0] = -84.540324, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1256499260, states[0] = -49.638379, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1267369638, states[0] = 6.244407, states[40]= 0.000120
Saving checkpoint... 
Iteration: 1278113765, states[0] = -84.076416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288876994, states[0] = 31.675416, states[40]= 0.012843
Saving checkpoint... 
Iteration: 1299354425, states[0] = -70.622510, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1309837614, states[0] = -84.609760, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1320590936, states[0] = -26.947796, states[40]= 0.000198
Saving checkpoint... 
Iteration: 1331216813, states[0] = -13.506497, states[40]= 0.000241
Saving checkpoint... 
Iteration: 1342075152, states[0] = 29.408940, states[40]= 0.000288
Saving checkpoint... 
Iteration: 1352986297, states[0] = 31.346537, states[40]= 0.040493
Saving checkpoint... 
Iteration: 1363896278, states[0] = -84.629316, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1374091414, states[0] = -54.755311, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1383876741, states[0] = -67.098223, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1393073489, states[0] = -62.996968, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1403186563, states[0] = -84.167073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413645489, states[0] = 30.453188, states[40]= 0.132519
Saving checkpoint... 
Iteration: 1423714573, states[0] = 31.677028, states[40]= 0.012483
Saving checkpoint... 
Iteration: 1433926362, states[0] = -83.824312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444074486, states[0] = -84.526810, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1451453658, states[0] = -82.075694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462120418, states[0] = -84.134064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473122845, states[0] = -84.562855, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1481928126, states[0] = -81.834124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493323068, states[0] = 18.803041, states[40]= 0.000014
Total time: 3000350.000000
State Variables:
 - v in component membrane (millivolt): -84.509527
 - CaMKt in component CaMK (millimolar): 0.056842
 - cass in component intracellular_ions (millimolar): 0.000112
 - nai in component intracellular_ions (millimolar): 7.015907
 - nass in component intracellular_ions (millimolar): 7.016081
 - ki in component intracellular_ions (millimolar): 144.562574
 - kss in component intracellular_ions (millimolar): 144.562547
 - cansr in component intracellular_ions (millimolar): 2.246833
 - cajsr in component intracellular_ions (millimolar): 1.862572
 - cai in component intracellular_ions (millimolar): 0.000112
 - m in component INa (dimensionless): 0.010300
 - hf in component INa (dimensionless): 0.570736
 - hs in component INa (dimensionless): 0.570499
 - j in component INa (dimensionless): 0.569159
 - hsp in component INa (dimensionless): 0.323648
 - jp in component INa (dimensionless): 0.567607
 - mL in component INaL (dimensionless): 0.000357
 - hL in component INaL (dimensionless): 0.316311
 - hLp in component INaL (dimensionless): 0.133605
 - a in component Ito (dimensionless): 0.001256
 - iF in component Ito (dimensionless): 0.999195
 - iS in component Ito (dimensionless): 0.302158
 - ap in component Ito (dimensionless): 0.000640
 - iFp in component Ito (dimensionless): 0.999195
 - iSp in component Ito (dimensionless): 0.331941
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.811450
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.990132
 - jca in component ICaL (dimensionless): 0.994171
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.007855
 - xrf in component IKr (dimensionless): 0.002185
 - xrs in component IKr (dimensionless): 0.730735
 - xs1 in component IKs (dimensionless): 0.427889
 - xs2 in component IKs (dimensionless): 0.000293
 - xk1 in component IK1 (dimensionless): 0.996800
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
07:42:00 (4157): called boinc_finish(0)

</stderr_txt>
]]>


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