𝕏

Task 55212410

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_500-conf_359_0
Workunit 26219804
Created 28 Jun 2024, 6:04:14 UTC
Sent 29 Jun 2024, 3:58:37 UTC
Report deadline 2 Jul 2024, 3:58:37 UTC
Received 29 Jun 2024, 7:38:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216894
Run time 2 hours 30 min 56 sec
CPU time 1 hours 56 min 9 sec
Validate state Valid
Credit 43.39
Device peak FLOPS 4.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.84 MB
Peak swap size 32.60 GB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_500-conf_359.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_500-conf_359_0_r1324361212_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_500-conf_359_0_r1324361212_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.995683
     * GNaL_b in INaL: 0.006206
     * Gto_b in Ito: 0.087984
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030489
     * GKs_b in IKs: 0.002098
     * GK1_b in IK1: 0.151475
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 66.178258
     * GKb_b in IKb: 0.003926
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032332
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11206185, states[0] = -84.527116, states[40]= 0.000001
Saving checkpoint... 
Iteration: 23513444, states[0] = 31.390826, states[40]= 0.018644
Saving checkpoint... 
Iteration: 35785822, states[0] = 24.733292, states[40]= 0.000008
Saving checkpoint... 
Iteration: 47429527, states[0] = -84.310165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58492281, states[0] = -84.740040, states[40]= 0.000001
Saving checkpoint... 
Iteration: 70343840, states[0] = -19.923817, states[40]= 0.000157
Saving checkpoint... 
Iteration: 82214812, states[0] = -84.618478, states[40]= 0.000001
Saving checkpoint... 
Iteration: 92710638, states[0] = -84.596095, states[40]= 0.000001
Saving checkpoint... 
Iteration: 102670985, states[0] = -84.247632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113261914, states[0] = 30.823924, states[40]= 0.033634
Saving checkpoint... 
Iteration: 123739588, states[0] = -84.754090, states[40]= 0.000001
Saving checkpoint... 
Iteration: 133813473, states[0] = 8.775291, states[40]= 0.000044
Saving checkpoint... 
Iteration: 144186600, states[0] = -84.416549, states[40]= 0.000001
Saving checkpoint... 
Iteration: 154593434, states[0] = -20.027159, states[40]= 0.000143
Saving checkpoint... 
Iteration: 165029376, states[0] = 27.326447, states[40]= 0.000061
Saving checkpoint... 
Iteration: 175377520, states[0] = -58.652764, states[40]= 0.000014
Saving checkpoint... 
Iteration: 185509651, states[0] = 30.155546, states[40]= 0.077138
Saving checkpoint... 
Iteration: 195854703, states[0] = -33.100894, states[40]= 0.000146
Saving checkpoint... 
Iteration: 206270528, states[0] = 30.425693, states[40]= 0.001456
Saving checkpoint... 
Iteration: 216898995, states[0] = -82.030775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227455138, states[0] = -84.563671, states[40]= 0.000001
Saving checkpoint... 
Iteration: 237862764, states[0] = -42.084168, states[40]= 0.000082
Saving checkpoint... 
Iteration: 248100675, states[0] = -28.534271, states[40]= 0.000158
Saving checkpoint... 
Iteration: 258415754, states[0] = -84.166150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268824470, states[0] = 0.692579, states[40]= 0.000131
Saving checkpoint... 
Iteration: 278598607, states[0] = -26.152943, states[40]= 0.000155
Saving checkpoint... 
Iteration: 289178726, states[0] = -84.336271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299926235, states[0] = -84.309418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310302744, states[0] = 15.370317, states[40]= 0.000012
Saving checkpoint... 
Iteration: 321257438, states[0] = 29.364018, states[40]= 0.172476
Saving checkpoint... 
Iteration: 331998038, states[0] = -84.783104, states[40]= 0.000001
Saving checkpoint... 
Iteration: 342825937, states[0] = -0.556132, states[40]= 0.000145
Saving checkpoint... 
Iteration: 353236478, states[0] = -84.735205, states[40]= 0.000001
Saving checkpoint... 
Iteration: 363462596, states[0] = -84.608020, states[40]= 0.000001
Saving checkpoint... 
Iteration: 373855134, states[0] = -33.585634, states[40]= 0.000143
Saving checkpoint... 
Iteration: 383982070, states[0] = -84.713837, states[40]= 0.000001
Saving checkpoint... 
Iteration: 394085316, states[0] = -10.217269, states[40]= 0.000184
Saving checkpoint... 
Iteration: 404313259, states[0] = 8.896232, states[40]= 0.000043
Saving checkpoint... 
Iteration: 414389778, states[0] = -73.907526, states[40]= 0.000002
Saving checkpoint... 
Iteration: 424267955, states[0] = 30.935906, states[40]= 0.003699
Saving checkpoint... 
Iteration: 433882044, states[0] = -64.083955, states[40]= 0.000007
Saving checkpoint... 
Iteration: 443469998, states[0] = -84.649050, states[40]= 0.000001
Saving checkpoint... 
Iteration: 452940374, states[0] = -84.439563, states[40]= 0.000001
Saving checkpoint... 
Iteration: 462521558, states[0] = 30.159537, states[40]= 0.001004
Saving checkpoint... 
Iteration: 472039448, states[0] = 22.582309, states[40]= 0.000003


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_500-conf_359.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_500-conf_359_0_r1324361212_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_500-conf_359_0_r1324361212_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.995683
     * GNaL_b in INaL: 0.006206
     * Gto_b in Ito: 0.087984
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030489
     * GKs_b in IKs: 0.002098
     * GK1_b in IK1: 0.151475
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 66.178258
     * GKb_b in IKb: 0.003926
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032332
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 472039448
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 22.582309 (After loading)
 - states[40]: 0.000003 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 483977581, states[0] = -84.687995, states[40]= 0.000001
Saving checkpoint... 
Iteration: 495229335, states[0] = -84.696302, states[40]= 0.000001
Saving checkpoint... 
Iteration: 505485501, states[0] = -84.724914, states[40]= 0.000001
Saving checkpoint... 
Iteration: 514735621, states[0] = -84.725092, states[40]= 0.000001
Saving checkpoint... 
Iteration: 523954958, states[0] = -84.550828, states[40]= 0.000001
Saving checkpoint... 
Iteration: 533203229, states[0] = -84.538141, states[40]= 0.000001
Saving checkpoint... 
Iteration: 542422972, states[0] = -84.262390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552813685, states[0] = 8.617908, states[40]= 0.000045
Saving checkpoint... 
Iteration: 561920974, states[0] = -84.236465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571768154, states[0] = 30.908178, states[40]= 0.003441
Saving checkpoint... 
Iteration: 582498002, states[0] = -84.773240, states[40]= 0.000001
Saving checkpoint... 
Iteration: 593287155, states[0] = 23.729145, states[40]= 0.000005
Saving checkpoint... 
Iteration: 603025466, states[0] = 28.888312, states[40]= 0.000246
Saving checkpoint... 
Iteration: 613839806, states[0] = -15.635229, states[40]= 0.000155
Saving checkpoint... 
Iteration: 624716762, states[0] = -84.623219, states[40]= 0.000001
Saving checkpoint... 
Iteration: 635621473, states[0] = -51.744990, states[40]= 0.000031
Saving checkpoint... 
Iteration: 646296014, states[0] = 19.144671, states[40]= 0.000005
Saving checkpoint... 
Iteration: 657317698, states[0] = 5.874733, states[40]= 0.000070
Saving checkpoint... 
Iteration: 667200955, states[0] = -84.516172, states[40]= 0.000001
Saving checkpoint... 
Iteration: 676654701, states[0] = -83.528587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686281793, states[0] = 26.268124, states[40]= 0.000026
Saving checkpoint... 
Iteration: 696334357, states[0] = -9.083399, states[40]= 0.000188
Saving checkpoint... 
Iteration: 707097937, states[0] = -25.354025, states[40]= 0.000153
Saving checkpoint... 
Iteration: 718051282, states[0] = 16.217823, states[40]= 0.000010
Saving checkpoint... 
Iteration: 728952954, states[0] = -84.528432, states[40]= 0.000001
Saving checkpoint... 
Iteration: 740043957, states[0] = 20.248616, states[40]= 0.000004
Saving checkpoint... 
Iteration: 750947829, states[0] = -84.489025, states[40]= 0.000001
Saving checkpoint... 
Iteration: 761802332, states[0] = 15.615984, states[40]= 0.000011
Saving checkpoint... 
Iteration: 772814519, states[0] = 8.066505, states[40]= 0.000049
Saving checkpoint... 
Iteration: 783789486, states[0] = 22.567858, states[40]= 0.000003
Saving checkpoint... 
Iteration: 794552997, states[0] = 15.231444, states[40]= 0.000012
Saving checkpoint... 
Iteration: 804549011, states[0] = 17.500377, states[40]= 0.000007
Saving checkpoint... 
Iteration: 814676398, states[0] = -84.290596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824959326, states[0] = -84.568778, states[40]= 0.000001
Saving checkpoint... 
Iteration: 835289700, states[0] = 22.460170, states[40]= 0.000003
Saving checkpoint... 
Iteration: 844777853, states[0] = 27.966044, states[40]= 0.000105
Saving checkpoint... 
Iteration: 855181062, states[0] = -84.337350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865662699, states[0] = -84.066974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876112373, states[0] = -41.617948, states[40]= 0.000085
Saving checkpoint... 
Iteration: 886623367, states[0] = -53.859844, states[40]= 0.000025
Saving checkpoint... 
Iteration: 896988938, states[0] = -84.724728, states[40]= 0.000001
Saving checkpoint... 
Iteration: 907465449, states[0] = -84.604265, states[40]= 0.000001
Saving checkpoint... 
Iteration: 917825667, states[0] = -0.303916, states[40]= 0.000142
Saving checkpoint... 
Iteration: 928144008, states[0] = -78.539808, states[40]= 0.000001
Saving checkpoint... 
Iteration: 938546474, states[0] = 18.899643, states[40]= 0.000005
Saving checkpoint... 
Iteration: 948373230, states[0] = -53.700889, states[40]= 0.000025
Saving checkpoint... 
Iteration: 958390405, states[0] = -74.609862, states[40]= 0.000002
Saving checkpoint... 
Iteration: 968442935, states[0] = -84.440900, states[40]= 0.000001
Saving checkpoint... 
Iteration: 978349460, states[0] = -27.102407, states[40]= 0.000157
Saving checkpoint... 
Iteration: 987685905, states[0] = -84.378398, states[40]= 0.000001
Saving checkpoint... 
Iteration: 997041380, states[0] = 21.602166, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1006741997, states[0] = -84.733248, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1016641608, states[0] = -76.018299, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1027146683, states[0] = -80.682415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037905008, states[0] = -83.550802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048945382, states[0] = -84.457816, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1060084799, states[0] = -9.579426, states[40]= 0.000186
Saving checkpoint... 
Iteration: 1070756217, states[0] = 29.131933, states[40]= 0.267011
Saving checkpoint... 
Iteration: 1081297682, states[0] = 18.241022, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1091636664, states[0] = -69.871255, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1101747712, states[0] = -84.751974, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1111554369, states[0] = 14.433548, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1121341103, states[0] = -17.192000, states[40]= 0.000148
Saving checkpoint... 
Iteration: 1131058923, states[0] = 11.679614, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1141418437, states[0] = -84.176819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152065619, states[0] = 7.330205, states[40]= 0.000056
Saving checkpoint... 
Iteration: 1163001270, states[0] = 36.186244, states[40]= 0.936615
Saving checkpoint... 
Iteration: 1174045484, states[0] = 19.439115, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1184698300, states[0] = -84.475539, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1195464778, states[0] = -84.588881, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1205635323, states[0] = -68.137802, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1215408883, states[0] = -83.890503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225266526, states[0] = 31.106195, states[40]= 0.006218
Saving checkpoint... 
Iteration: 1235004452, states[0] = 30.017731, states[40]= 0.497479
Saving checkpoint... 
Iteration: 1244486202, states[0] = -84.699241, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1253034536, states[0] = 25.005843, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1261422682, states[0] = -84.229941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270694762, states[0] = -84.444006, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1279655491, states[0] = -83.598535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289412396, states[0] = -84.039629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298485164, states[0] = -84.692474, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1308473691, states[0] = -84.635504, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1319289682, states[0] = 22.476739, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1330085248, states[0] = -10.092475, states[40]= 0.000184
Saving checkpoint... 
Iteration: 1340759423, states[0] = 30.083110, states[40]= 0.083741
Saving checkpoint... 
Iteration: 1351303301, states[0] = 15.063759, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1361602294, states[0] = -30.324756, states[40]= 0.000156
Saving checkpoint... 
Iteration: 1372355108, states[0] = -33.503902, states[40]= 0.000143
Saving checkpoint... 
Iteration: 1382933002, states[0] = -84.335291, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1393246909, states[0] = -84.737604, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1403845073, states[0] = -21.955543, states[40]= 0.000144
Saving checkpoint... 
Iteration: 1414613506, states[0] = -42.841976, states[40]= 0.000076
Saving checkpoint... 
Iteration: 1425465150, states[0] = -84.582118, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1435891006, states[0] = -75.270571, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1445306216, states[0] = 13.339083, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1454853950, states[0] = -32.195390, states[40]= 0.000150
Saving checkpoint... 
Iteration: 1465040872, states[0] = 21.871204, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1475505274, states[0] = 29.321425, states[40]= 0.372788
Saving checkpoint... 
Iteration: 1486074313, states[0] = 0.857727, states[40]= 0.000128
Saving checkpoint... 
Iteration: 1490131934, states[0] = -63.852323, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1497743851, states[0] = -84.721626, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.620722
 - CaMKt in component CaMK (millimolar): 0.086159
 - cass in component intracellular_ions (millimolar): 0.000121
 - nai in component intracellular_ions (millimolar): 7.129243
 - nass in component intracellular_ions (millimolar): 7.129447
 - ki in component intracellular_ions (millimolar): 144.319738
 - kss in component intracellular_ions (millimolar): 144.319706
 - cansr in component intracellular_ions (millimolar): 2.515566
 - cajsr in component intracellular_ions (millimolar): 1.929680
 - cai in component intracellular_ions (millimolar): 0.000120
 - m in component INa (dimensionless): 0.010186
 - hf in component INa (dimensionless): 0.575204
 - hs in component INa (dimensionless): 0.574810
 - j in component INa (dimensionless): 0.572281
 - hsp in component INa (dimensionless): 0.327181
 - jp in component INa (dimensionless): 0.567908
 - mL in component INaL (dimensionless): 0.000349
 - hL in component INaL (dimensionless): 0.285408
 - hLp in component INaL (dimensionless): 0.118024
 - a in component Ito (dimensionless): 0.001247
 - iF in component Ito (dimensionless): 0.999210
 - iS in component Ito (dimensionless): 0.248820
 - ap in component Ito (dimensionless): 0.000635
 - iFp in component Ito (dimensionless): 0.999210
 - iSp in component Ito (dimensionless): 0.274535
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.779449
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.981188
 - jca in component ICaL (dimensionless): 0.985842
 - ffp in component ICaL (dimensionless): 0.999999
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.010825
 - xrf in component IKr (dimensionless): 0.008023
 - xrs in component IKr (dimensionless): 0.775752
 - xs1 in component IKs (dimensionless): 0.466418
 - xs2 in component IKs (dimensionless): 0.000373
 - xk1 in component IK1 (dimensionless): 0.996776
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
23:36:47 (97765): called boinc_finish(0)

</stderr_txt>
]]>


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