𝕏

Task 55212408

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_500-conf_259_0
Workunit 26219803
Created 28 Jun 2024, 6:04:14 UTC
Sent 29 Jun 2024, 3:58:37 UTC
Report deadline 2 Jul 2024, 3:58:37 UTC
Received 29 Jun 2024, 18:12:35 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216894
Run time 2 hours 34 min 16 sec
CPU time 1 hours 58 min 9 sec
Validate state Valid
Credit 43.76
Device peak FLOPS 4.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.91 MB
Peak swap size 32.60 GB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_500-conf_259.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_500-conf_259_0_r160157998_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_500-conf_259_0_r160157998_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.865252
     * GNaL_b in INaL: 0.005651
     * Gto_b in Ito: 0.098870
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033499
     * GKs_b in IKs: 0.001864
     * GK1_b in IK1: 0.178674
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 69.856813
     * GKb_b in IKb: 0.003825
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.022021
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 7194947, states[0] = -84.700923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17882464, states[0] = -70.309472, states[40]= 0.000003
Saving checkpoint... 
Iteration: 28339731, states[0] = -16.183591, states[40]= 0.000170
Saving checkpoint... 
Iteration: 38575138, states[0] = -0.145897, states[40]= 0.000137
Saving checkpoint... 
Iteration: 48854844, states[0] = -36.117369, states[40]= 0.000092
Saving checkpoint... 
Iteration: 58932257, states[0] = -84.546959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69006884, states[0] = 28.405958, states[40]= 0.211603
Saving checkpoint... 
Iteration: 78252214, states[0] = 34.634284, states[40]= 1.077331
Saving checkpoint... 
Iteration: 88334363, states[0] = -11.200597, states[40]= 0.000129
Saving checkpoint... 
Iteration: 99211680, states[0] = -84.765724, states[40]= 0.000001
Saving checkpoint... 
Iteration: 109885778, states[0] = -78.221939, states[40]= 0.000001
Saving checkpoint... 
Iteration: 120341711, states[0] = -20.934908, states[40]= 0.000095
Saving checkpoint... 
Iteration: 130544195, states[0] = 19.935028, states[40]= 0.000003
Saving checkpoint... 
Iteration: 141073830, states[0] = 0.131057, states[40]= 0.000097
Saving checkpoint... 
Iteration: 151600428, states[0] = -31.931857, states[40]= 0.000093
Saving checkpoint... 
Iteration: 160607172, states[0] = -40.169235, states[40]= 0.000059
Saving checkpoint... 
Iteration: 171046700, states[0] = 18.555007, states[40]= 0.000004
Saving checkpoint... 
Iteration: 181093607, states[0] = -23.442101, states[40]= 0.000095
Saving checkpoint... 
Iteration: 191135015, states[0] = -77.451895, states[40]= 0.000001
Saving checkpoint... 
Iteration: 201294855, states[0] = 19.565062, states[40]= 0.000003
Saving checkpoint... 
Iteration: 211432620, states[0] = -84.566161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221781281, states[0] = 26.312574, states[40]= 0.000030
Saving checkpoint... 
Iteration: 232082392, states[0] = -8.992527, states[40]= 0.000129
Saving checkpoint... 
Iteration: 242297724, states[0] = 17.981567, states[40]= 0.000004
Saving checkpoint... 
Iteration: 252833660, states[0] = -10.574838, states[40]= 0.000125
Saving checkpoint... 
Iteration: 263439000, states[0] = -84.615692, states[40]= 0.000001
Saving checkpoint... 
Iteration: 273244462, states[0] = -84.907644, states[40]= 0.000001
Saving checkpoint... 
Iteration: 283078010, states[0] = -3.964977, states[40]= 0.000123
Saving checkpoint... 
Iteration: 293106301, states[0] = -39.127166, states[40]= 0.000063
Saving checkpoint... 
Iteration: 303339540, states[0] = -18.210496, states[40]= 0.000097
Saving checkpoint... 
Iteration: 313665884, states[0] = -84.402480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323995204, states[0] = -84.908134, states[40]= 0.000001
Saving checkpoint... 
Iteration: 334963092, states[0] = -84.769544, states[40]= 0.000001
Saving checkpoint... 
Iteration: 346061692, states[0] = 9.424593, states[40]= 0.000028
Saving checkpoint... 
Iteration: 356896333, states[0] = -83.815240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367566426, states[0] = 6.095881, states[40]= 0.000048
Saving checkpoint... 
Iteration: 378529919, states[0] = 26.905824, states[40]= 0.000049
Saving checkpoint... 
Iteration: 387698720, states[0] = -84.680662, states[40]= 0.000001
Saving checkpoint... 
Iteration: 397172518, states[0] = -84.466989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407344118, states[0] = -24.088981, states[40]= 0.000095
Saving checkpoint... 
Iteration: 416942850, states[0] = -84.638390, states[40]= 0.000001
Saving checkpoint... 
Iteration: 427201030, states[0] = -84.694286, states[40]= 0.000001
Saving checkpoint... 
Iteration: 437928972, states[0] = -84.525387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448811586, states[0] = 9.498104, states[40]= 0.000027
Saving checkpoint... 
Iteration: 459956169, states[0] = -84.725020, states[40]= 0.000001
Saving checkpoint... 
Iteration: 471098888, states[0] = -30.048253, states[40]= 0.000097
Saving checkpoint... 
Iteration: 482137091, states[0] = -79.741545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493219506, states[0] = -84.796298, states[40]= 0.000001
Saving checkpoint... 
Iteration: 503692217, states[0] = -84.630224, states[40]= 0.000001
Saving checkpoint... 
Iteration: 514355176, states[0] = -37.746092, states[40]= 0.000070
Saving checkpoint... 
Iteration: 524813322, states[0] = 8.314272, states[40]= 0.000034
Saving checkpoint... 
Iteration: 535364262, states[0] = -48.853867, states[40]= 0.000026
Saving checkpoint... 
Iteration: 545948177, states[0] = -84.670601, states[40]= 0.000001
Saving checkpoint... 
Iteration: 556530392, states[0] = 26.705765, states[40]= 0.000041
Saving checkpoint... 
Iteration: 566506330, states[0] = 28.212766, states[40]= 0.259609
Saving checkpoint... 
Iteration: 576376007, states[0] = -64.280420, states[40]= 0.000004
Saving checkpoint... 
Iteration: 587261809, states[0] = 30.229033, states[40]= 0.034940
Saving checkpoint... 
Iteration: 598118275, states[0] = -53.884639, states[40]= 0.000015
Saving checkpoint... 
Iteration: 609069662, states[0] = 3.632874, states[40]= 0.000066
Saving checkpoint... 
Iteration: 619670922, states[0] = -84.442151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628516145, states[0] = 30.723178, states[40]= 0.007067
Saving checkpoint... 
Iteration: 637408767, states[0] = -84.303272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646752642, states[0] = 33.259266, states[40]= 0.941768
Saving checkpoint... 
Iteration: 656455636, states[0] = -84.713875, states[40]= 0.000001
Saving checkpoint... 
Iteration: 667074624, states[0] = -0.602526, states[40]= 0.000102
Saving checkpoint... 
Iteration: 677520628, states[0] = 30.111944, states[40]= 0.001375
Saving checkpoint... 
Iteration: 686968414, states[0] = -84.783092, states[40]= 0.000001
Saving checkpoint... 
Iteration: 696325313, states[0] = -1.247572, states[40]= 0.000107
Saving checkpoint... 
Iteration: 705608090, states[0] = -41.278013, states[40]= 0.000054
Saving checkpoint... 
Iteration: 714166177, states[0] = -84.389167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723666384, states[0] = -84.391004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733664778, states[0] = -84.373058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743665926, states[0] = -84.385240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754589908, states[0] = -18.664489, states[40]= 0.000096
Saving checkpoint... 
Iteration: 765420612, states[0] = -84.433076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775997795, states[0] = -84.898643, states[40]= 0.000001
Saving checkpoint... 
Iteration: 786491644, states[0] = -84.877385, states[40]= 0.000001
Saving checkpoint... 
Iteration: 796616233, states[0] = -51.291010, states[40]= 0.000020
Saving checkpoint... 
Iteration: 807058632, states[0] = 11.447984, states[40]= 0.000019
Saving checkpoint... 
Iteration: 817665803, states[0] = -84.380858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828300663, states[0] = 16.313932, states[40]= 0.000007
Saving checkpoint... 
Iteration: 838888860, states[0] = -81.195255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849788109, states[0] = 23.092947, states[40]= 0.000004
Saving checkpoint... 
Iteration: 859838548, states[0] = -16.884169, states[40]= 0.000100
Saving checkpoint... 
Iteration: 869902749, states[0] = -84.177564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880319257, states[0] = 3.959489, states[40]= 0.000064
Saving checkpoint... 
Iteration: 890590012, states[0] = -18.792101, states[40]= 0.000096
Saving checkpoint... 
Iteration: 901452546, states[0] = -84.684829, states[40]= 0.000001
Saving checkpoint... 
Iteration: 912236966, states[0] = -84.855191, states[40]= 0.000001
Saving checkpoint... 
Iteration: 922953292, states[0] = -84.688665, states[40]= 0.000001
Saving checkpoint... 
Iteration: 933777599, states[0] = 27.867458, states[40]= 0.000111
Saving checkpoint... 
Iteration: 944524785, states[0] = 28.908038, states[40]= 0.000306
Saving checkpoint... 
Iteration: 955381053, states[0] = -71.754919, states[40]= 0.000002
Saving checkpoint... 
Iteration: 966144600, states[0] = -83.522292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976699969, states[0] = -84.665125, states[40]= 0.000001
Saving checkpoint... 
Iteration: 987273958, states[0] = 29.184685, states[40]= 0.000412
Saving checkpoint... 
Iteration: 996517486, states[0] = 30.643421, states[40]= 0.004322
Saving checkpoint... 
Iteration: 1005345408, states[0] = -25.682233, states[40]= 0.000097
Saving checkpoint... 
Iteration: 1013900187, states[0] = -84.077480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021879170, states[0] = -68.898581, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1030382108, states[0] = -73.323940, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1039394894, states[0] = -83.570940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048548023, states[0] = 17.826738, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1058090542, states[0] = -19.470748, states[40]= 0.000095
Saving checkpoint... 
Iteration: 1067544649, states[0] = 19.689662, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1076927301, states[0] = -84.484223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086027096, states[0] = 28.066059, states[40]= 0.000133
Saving checkpoint... 
Iteration: 1095333866, states[0] = -10.792905, states[40]= 0.000124
Saving checkpoint... 
Iteration: 1104975145, states[0] = -84.798370, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1115016913, states[0] = 30.693054, states[40]= 0.005330
Saving checkpoint... 
Iteration: 1125723647, states[0] = -84.790674, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1137078296, states[0] = -4.234365, states[40]= 0.000124
Saving checkpoint... 
Iteration: 1147343490, states[0] = -23.250568, states[40]= 0.000094
Saving checkpoint... 
Iteration: 1157487306, states[0] = -84.846672, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1167467167, states[0] = -84.757470, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1177697550, states[0] = -84.640756, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1187928020, states[0] = -84.486210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197849287, states[0] = -30.499764, states[40]= 0.000096
Saving checkpoint... 
Iteration: 1207384054, states[0] = -76.074755, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1216436861, states[0] = -84.560162, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1224697622, states[0] = -84.639344, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1232761433, states[0] = 30.130295, states[40]= 0.040121
Saving checkpoint... 
Iteration: 1241298129, states[0] = 17.770277, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1250418724, states[0] = -84.393972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260236914, states[0] = -84.841075, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1268713482, states[0] = -84.734056, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1280152154, states[0] = -84.141862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287073057, states[0] = 0.827706, states[40]= 0.000090
Saving checkpoint... 
Iteration: 1298318795, states[0] = 4.330624, states[40]= 0.000061
Saving checkpoint... 
Iteration: 1309329982, states[0] = -6.085894, states[40]= 0.000130
Saving checkpoint... 
Iteration: 1316287503, states[0] = 23.401966, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1326770508, states[0] = 30.149022, states[40]= 0.001436
Saving checkpoint... 
Iteration: 1337097579, states[0] = -28.376186, states[40]= 0.000098
Saving checkpoint... 
Iteration: 1347042040, states[0] = 21.085706, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1356455192, states[0] = -84.682910, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1365726604, states[0] = -84.794452, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1374806144, states[0] = 13.031356, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1383875522, states[0] = -63.504741, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1393284106, states[0] = 25.042806, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1403100380, states[0] = -31.834605, states[40]= 0.000093
Saving checkpoint... 
Iteration: 1413295899, states[0] = 19.013700, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1422973454, states[0] = -84.777846, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1433451644, states[0] = -84.657556, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1443855739, states[0] = -38.375416, states[40]= 0.000067
Saving checkpoint... 
Iteration: 1454145129, states[0] = -83.586931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463381863, states[0] = -72.903026, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1473946702, states[0] = -84.622922, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1482797621, states[0] = 18.059727, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1489501004, states[0] = 34.881156, states[40]= 0.613211
Saving checkpoint... 
Iteration: 1499427506, states[0] = -84.468817, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.752548
 - CaMKt in component CaMK (millimolar): 0.087391
 - cass in component intracellular_ions (millimolar): 0.000121
 - nai in component intracellular_ions (millimolar): 7.100152
 - nass in component intracellular_ions (millimolar): 7.100362
 - ki in component intracellular_ions (millimolar): 144.336588
 - kss in component intracellular_ions (millimolar): 144.336554
 - cansr in component intracellular_ions (millimolar): 2.525088
 - cajsr in component intracellular_ions (millimolar): 1.928325
 - cai in component intracellular_ions (millimolar): 0.000120
 - m in component INa (dimensionless): 0.010052
 - hf in component INa (dimensionless): 0.580489
 - hs in component INa (dimensionless): 0.580151
 - j in component INa (dimensionless): 0.578049
 - hsp in component INa (dimensionless): 0.332133
 - jp in component INa (dimensionless): 0.574672
 - mL in component INaL (dimensionless): 0.000341
 - hL in component INaL (dimensionless): 0.299708
 - hLp in component INaL (dimensionless): 0.126889
 - a in component Ito (dimensionless): 0.001236
 - iF in component Ito (dimensionless): 0.999228
 - iS in component Ito (dimensionless): 0.258245
 - ap in component Ito (dimensionless): 0.000630
 - iFp in component Ito (dimensionless): 0.999228
 - iSp in component Ito (dimensionless): 0.286781
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.785977
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.982731
 - jca in component ICaL (dimensionless): 0.986848
 - ffp in component ICaL (dimensionless): 0.999999
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.010824
 - xrf in component IKr (dimensionless): 0.006113
 - xrs in component IKr (dimensionless): 0.764085
 - xs1 in component IKs (dimensionless): 0.459372
 - xs2 in component IKs (dimensionless): 0.000335
 - xk1 in component IK1 (dimensionless): 0.996742
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
10:37:36 (6423): called boinc_finish(0)

</stderr_txt>
]]>


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