𝕏

Task 55209351

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_56_1
Workunit 26218278
Created 28 Jun 2024, 6:02:54 UTC
Sent 29 Jun 2024, 3:32:06 UTC
Report deadline 2 Jul 2024, 6:24:54 UTC
Received 29 Jun 2024, 11:52:27 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230524
Run time 2 hours 33 min 12 sec
CPU time 2 hours 27 min 51 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.47 MB
Peak swap size 2.35 GB
Peak disk usage 0.07 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_56.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_56_1_r1713654093_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_56_1_r1713654093_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 90.882022
     * GNaL_b in INaL: 0.004673
     * Gto_b in Ito: 0.091987
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031710
     * GKs_b in IKs: 0.001759
     * GK1_b in IK1: 0.041974
     * Gncx_b in INaCa_i: 0.000975
     * Pnak_b in INaK: 70.783089
     * GKb_b in IKb: 0.003930
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019376
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11198459, states[0] = -81.877907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22300843, states[0] = -90.268252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33536929, states[0] = 21.988504, states[40]= 0.000960
Saving checkpoint... 
Iteration: 44771813, states[0] = -89.316042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56071766, states[0] = 7.925608, states[40]= 0.003038
Saving checkpoint... 
Iteration: 67299667, states[0] = -89.901418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78497111, states[0] = -90.727459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89736284, states[0] = -86.357862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100913439, states[0] = -90.583092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112155448, states[0] = -60.346279, states[40]= 0.000013
Saving checkpoint... 
Iteration: 123424517, states[0] = -90.594467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134654889, states[0] = -59.950169, states[40]= 0.000014
Saving checkpoint... 
Iteration: 145866149, states[0] = -90.400085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157090189, states[0] = -2.724091, states[40]= 0.003436
Saving checkpoint... 
Iteration: 168344447, states[0] = -90.276891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179582507, states[0] = 2.420097, states[40]= 0.003598
Saving checkpoint... 
Iteration: 190668601, states[0] = -67.370697, states[40]= 0.000004
Saving checkpoint... 
Iteration: 201889867, states[0] = -90.487160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213116262, states[0] = -27.379991, states[40]= 0.000919
Saving checkpoint... 
Iteration: 224380855, states[0] = -90.454006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235602698, states[0] = -13.987988, states[40]= 0.001630
Saving checkpoint... 
Iteration: 246559182, states[0] = 13.719859, states[40]= 0.002147
Saving checkpoint... 
Iteration: 257792557, states[0] = -89.674908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269031790, states[0] = 23.974849, states[40]= 0.000801
Saving checkpoint... 
Iteration: 280201090, states[0] = -79.030195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291433418, states[0] = -90.595758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302614913, states[0] = -26.079833, states[40]= 0.000956
Saving checkpoint... 
Iteration: 313868817, states[0] = -90.402880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325089417, states[0] = -2.129078, states[40]= 0.003492
Saving checkpoint... 
Iteration: 336344733, states[0] = -90.273103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347411834, states[0] = -90.548499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358675147, states[0] = -70.252153, states[40]= 0.000002
Saving checkpoint... 
Iteration: 369928206, states[0] = -90.585080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381184540, states[0] = -73.849510, states[40]= 0.000001
Saving checkpoint... 
Iteration: 392442881, states[0] = -90.611465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403639468, states[0] = -48.524912, states[40]= 0.000091
Saving checkpoint... 
Iteration: 414908619, states[0] = -90.539823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426149002, states[0] = -55.951989, states[40]= 0.000027
Saving checkpoint... 
Iteration: 437211643, states[0] = -81.718461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448421299, states[0] = -90.570067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459660355, states[0] = -63.133111, states[40]= 0.000008
Saving checkpoint... 
Iteration: 470876511, states[0] = -90.434517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482114425, states[0] = -25.608659, states[40]= 0.000967
Saving checkpoint... 
Iteration: 493360272, states[0] = -90.360887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504442450, states[0] = -90.610048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515699174, states[0] = -78.490603, states[40]= 0.000001
Saving checkpoint... 
Iteration: 526920033, states[0] = -90.566757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538183648, states[0] = -73.530504, states[40]= 0.000001
Saving checkpoint... 
Iteration: 549374980, states[0] = -90.427777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560535758, states[0] = 22.666375, states[40]= 0.000903
Saving checkpoint... 
Iteration: 571749414, states[0] = -87.679116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582976745, states[0] = -90.653323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594205551, states[0] = -80.218693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605455502, states[0] = -90.628840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616686810, states[0] = -74.636715, states[40]= 0.000001
Saving checkpoint... 
Iteration: 627731504, states[0] = -85.549734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638956474, states[0] = -90.629930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650187099, states[0] = -74.734917, states[40]= 0.000001
Saving checkpoint... 
Iteration: 661302072, states[0] = -89.843263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664775223, states[0] = -89.193976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675968316, states[0] = -90.644063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687167323, states[0] = -66.748912, states[40]= 0.000004
Saving checkpoint... 
Iteration: 698244831, states[0] = -87.239233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709423111, states[0] = -90.572353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720657724, states[0] = -61.620415, states[40]= 0.000010
Saving checkpoint... 
Iteration: 731833052, states[0] = -90.187206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743026273, states[0] = 25.563631, states[40]= 0.000816
Saving checkpoint... 
Iteration: 754118952, states[0] = -29.930985, states[40]= 0.000813
Saving checkpoint... 
Iteration: 765359527, states[0] = -90.355329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776586634, states[0] = -0.176957, states[40]= 0.003605
Saving checkpoint... 
Iteration: 787844571, states[0] = -90.269064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799089292, states[0] = -2.035473, states[40]= 0.003500
Saving checkpoint... 
Iteration: 810379517, states[0] = -90.444211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821557417, states[0] = 14.447504, states[40]= 0.002023
Saving checkpoint... 
Iteration: 832788184, states[0] = -89.573582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843967254, states[0] = -90.641824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855170718, states[0] = -68.332101, states[40]= 0.000003
Saving checkpoint... 
Iteration: 866385427, states[0] = -90.465819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877597137, states[0] = -8.557243, states[40]= 0.002546
Saving checkpoint... 
Iteration: 888806125, states[0] = -89.902201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900043549, states[0] = 19.860374, states[40]= 0.001207
Saving checkpoint... 
Iteration: 911083908, states[0] = 1.579261, states[40]= 0.003620
Saving checkpoint... 
Iteration: 922275132, states[0] = -89.188637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933443529, states[0] = -90.609092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944634258, states[0] = -44.015449, states[40]= 0.000174
Saving checkpoint... 
Iteration: 955768633, states[0] = -88.923497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966929589, states[0] = -90.584032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978101130, states[0] = -12.413019, states[40]= 0.001866
Saving checkpoint... 
Iteration: 989284292, states[0] = -89.474496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000422989, states[0] = -90.570249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011462647, states[0] = -90.635406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022556156, states[0] = 14.960317, states[40]= 0.001936
Saving checkpoint... 
Iteration: 1033708830, states[0] = -81.039658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044888053, states[0] = -90.473890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056067481, states[0] = 10.145268, states[40]= 0.002756
Saving checkpoint... 
Iteration: 1067198780, states[0] = -78.373764, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1078405665, states[0] = -90.527727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089509714, states[0] = 26.749405, states[40]= 0.052666
Saving checkpoint... 
Iteration: 1100726426, states[0] = -84.719570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111924836, states[0] = -90.573467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123080406, states[0] = 3.654369, states[40]= 0.003538
Saving checkpoint... 
Iteration: 1134252565, states[0] = -87.939175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145446293, states[0] = -90.612119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156644853, states[0] = -52.868286, states[40]= 0.000046
Saving checkpoint... 
Iteration: 1167776465, states[0] = -89.234068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178979590, states[0] = -90.652234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190001943, states[0] = 39.870756, states[40]= 0.533371
Saving checkpoint... 
Iteration: 1201192594, states[0] = -76.522545, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1212389280, states[0] = -90.477015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223475821, states[0] = -90.648401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234735987, states[0] = -86.186525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246026825, states[0] = 25.421522, states[40]= 0.000797
Saving checkpoint... 
Iteration: 1257242450, states[0] = -86.979082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268496251, states[0] = -90.664780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279721627, states[0] = -83.840260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290934061, states[0] = -90.590497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302173646, states[0] = -69.614152, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1313409002, states[0] = -90.535115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324641941, states[0] = -50.561733, states[40]= 0.000066
Saving checkpoint... 
Iteration: 1335955390, states[0] = -90.624085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347343939, states[0] = -90.261297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358728447, states[0] = -85.058118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369956181, states[0] = -90.624933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381220814, states[0] = -83.681160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392509793, states[0] = 26.758548, states[40]= 0.051267
Saving checkpoint... 
Iteration: 1403909995, states[0] = -90.537107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415318981, states[0] = -90.054952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426709871, states[0] = -81.288891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438142167, states[0] = -50.743977, states[40]= 0.000064
Saving checkpoint... 
Iteration: 1449537454, states[0] = 22.078677, states[40]= 0.000959
Saving checkpoint... 
Iteration: 1460946453, states[0] = -90.610376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472347545, states[0] = -90.283364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483704870, states[0] = -80.034122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495098081, states[0] = -9.441100, states[40]= 0.002384
Saving checkpoint... 
Iteration: 1506383147, states[0] = 20.897287, states[40]= 0.002828
Saving checkpoint... 
Iteration: 1517571294, states[0] = -41.455150, states[40]= 0.000325
Saving checkpoint... 
Iteration: 1528760231, states[0] = 26.538278, states[40]= 0.050407
Saving checkpoint... 
Iteration: 1539948875, states[0] = -90.049926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1550818849, states[0] = -88.925311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1561893275, states[0] = -89.100802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1572998465, states[0] = -88.829005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1584107753, states[0] = -87.936675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1595142000, states[0] = -33.847969, states[40]= 0.000673
Saving checkpoint... 
Iteration: 1606207930, states[0] = -87.943400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1617255135, states[0] = -87.236620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628288767, states[0] = -86.992416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1639269554, states[0] = -85.663679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1650296337, states[0] = -79.580324, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1661303423, states[0] = -85.753660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1672247354, states[0] = -84.797865, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -84.457314
 - CaMKt in component CaMK (millimolar): 0.001101
 - cass in component intracellular_ions (millimolar): 0.000085
 - nai in component intracellular_ions (millimolar): 6.202119
 - nass in component intracellular_ions (millimolar): 6.202203
 - ki in component intracellular_ions (millimolar): 145.691763
 - kss in component intracellular_ions (millimolar): 145.691751
 - cansr in component intracellular_ions (millimolar): 1.537529
 - cajsr in component intracellular_ions (millimolar): 1.537669
 - cai in component intracellular_ions (millimolar): 0.000088
 - m in component INa (dimensionless): 0.010354
 - hf in component INa (dimensionless): 0.568631
 - hs in component INa (dimensionless): 0.568669
 - j in component INa (dimensionless): 0.568844
 - hsp in component INa (dimensionless): 0.322570
 - jp in component INa (dimensionless): 0.568945
 - mL in component INaL (dimensionless): 0.000360
 - hL in component INaL (dimensionless): 0.401583
 - hLp in component INaL (dimensionless): 0.229618
 - a in component Ito (dimensionless): 0.001261
 - iF in component Ito (dimensionless): 0.999189
 - iS in component Ito (dimensionless): 0.994054
 - ap in component Ito (dimensionless): 0.000642
 - iFp in component Ito (dimensionless): 0.999189
 - iSp in component Ito (dimensionless): 0.996454
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998852
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002772
 - xrf in component IKr (dimensionless): 0.000013
 - xrs in component IKr (dimensionless): 0.011350
 - xs1 in component IKs (dimensionless): 0.024438
 - xs2 in component IKs (dimensionless): 0.000283
 - xk1 in component IK1 (dimensionless): 0.999052
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
03:47:41 (74269): called boinc_finish(0)

</stderr_txt>
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