𝕏

Task 55208930

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_500-conf_755_0
Workunit 26218068
Created 28 Jun 2024, 6:02:43 UTC
Sent 29 Jun 2024, 3:30:20 UTC
Report deadline 2 Jul 2024, 3:30:20 UTC
Received 1 Jul 2024, 13:25:31 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222979
Run time 53 min 46 sec
CPU time 35 min 54 sec
Validate state Valid
Credit 42.85
Device peak FLOPS 3.64 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 3.00 MB
Peak swap size 391.86 GB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_500-conf_755.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_500-conf_755_0_r1232907513_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_500-conf_755_0_r1232907513_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 108.630683
     * GNaL_b in INaL: 0.004381
     * Gto_b in Ito: 0.090166
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031859
     * GKs_b in IKs: 0.002046
     * GK1_b in IK1: 0.157248
     * Gncx_b in INaCa_i: 0.000977
     * Pnak_b in INaK: 67.425261
     * GKb_b in IKb: 0.003757
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036494
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 30059063, states[0] = -2.362356, states[40]= 0.004520
Saving checkpoint... 
Iteration: 48934042, states[0] = -87.318100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70490267, states[0] = -87.411923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94802488, states[0] = 3.087037, states[40]= 0.005340
Saving checkpoint... 
Iteration: 126007704, states[0] = 23.877331, states[40]= 0.078350
Saving checkpoint... 
Iteration: 155546221, states[0] = 7.253753, states[40]= 0.005715
Saving checkpoint... 
Iteration: 176862127, states[0] = -67.119038, states[40]= 0.000002
Saving checkpoint... 
Iteration: 200703979, states[0] = -87.351452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225698789, states[0] = -87.341278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252377687, states[0] = -85.694512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280401036, states[0] = -87.215154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307733460, states[0] = -87.398658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332482717, states[0] = -87.397624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359500215, states[0] = -60.932336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384417558, states[0] = -87.266459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407107555, states[0] = -60.668629, states[40]= 0.000005
Saving checkpoint... 
Iteration: 434614141, states[0] = -70.132151, states[40]= 0.000001
Saving checkpoint... 
Iteration: 458538968, states[0] = 11.527755, states[40]= 0.006082
Saving checkpoint... 
Iteration: 486029633, states[0] = 16.350617, states[40]= 0.006874
Saving checkpoint... 
Iteration: 511530287, states[0] = 16.040402, states[40]= 0.006791
Saving checkpoint... 
Iteration: 536005399, states[0] = 26.204047, states[40]= 0.121096
Saving checkpoint... 
Iteration: 557135283, states[0] = -86.991220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575907600, states[0] = -87.236915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597245990, states[0] = -87.414141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624282608, states[0] = 14.902427, states[40]= 0.006542
Saving checkpoint... 
Iteration: 653082165, states[0] = -28.819950, states[40]= 0.000488


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_500-conf_755.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_500-conf_755_0_r1232907513_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_500-conf_755_0_r1232907513_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 108.630683
     * GNaL_b in INaL: 0.004381
     * Gto_b in Ito: 0.090166
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031859
     * GKs_b in IKs: 0.002046
     * GK1_b in IK1: 0.157248
     * Gncx_b in INaCa_i: 0.000977
     * Pnak_b in INaK: 67.425261
     * GKb_b in IKb: 0.003757
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036494
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 653082165
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -28.819950 (After loading)
 - states[40]: 0.000488 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 680238804, states[0] = -87.405282, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_500-conf_755.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_500-conf_755_0_r1232907513_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_500-conf_755_0_r1232907513_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 108.630683
     * GNaL_b in INaL: 0.004381
     * Gto_b in Ito: 0.090166
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031859
     * GKs_b in IKs: 0.002046
     * GK1_b in IK1: 0.157248
     * Gncx_b in INaCa_i: 0.000977
     * Pnak_b in INaK: 67.425261
     * GKb_b in IKb: 0.003757
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036494
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 680238804
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -87.405282 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 695991089, states[0] = -87.408134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712566811, states[0] = -9.828363, states[40]= 0.002792
Saving checkpoint... 
Iteration: 726702445, states[0] = -87.347927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743526050, states[0] = 17.960449, states[40]= 0.007491
Saving checkpoint... 
Iteration: 758021379, states[0] = 19.795519, states[40]= 0.009167
Saving checkpoint... 
Iteration: 775535588, states[0] = 13.364230, states[40]= 0.006297
Saving checkpoint... 
Iteration: 792639980, states[0] = -87.135088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805656183, states[0] = -87.232197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820125660, states[0] = -84.691995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844304305, states[0] = 1.805637, states[40]= 0.005190
Saving checkpoint... 
Iteration: 864130358, states[0] = -86.449471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879914606, states[0] = -87.257571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896480815, states[0] = -87.394427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913344702, states[0] = -44.245253, states[40]= 0.000067
Saving checkpoint... 
Iteration: 928185850, states[0] = -87.312600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941585629, states[0] = -33.095388, states[40]= 0.000308
Saving checkpoint... 
Iteration: 954843912, states[0] = -43.268320, states[40]= 0.000078
Saving checkpoint... 
Iteration: 969785087, states[0] = 13.628411, states[40]= 0.006334
Saving checkpoint... 
Iteration: 987660960, states[0] = -87.246759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004835260, states[0] = -32.641328, states[40]= 0.000325
Saving checkpoint... 
Iteration: 1016413633, states[0] = -87.254614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030137039, states[0] = -87.065121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046810449, states[0] = -3.230536, states[40]= 0.004349
Saving checkpoint... 
Iteration: 1063473349, states[0] = -87.383402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078511021, states[0] = 22.655221, states[40]= 0.037716
Saving checkpoint... 
Iteration: 1095518172, states[0] = 20.850805, states[40]= 0.011860
Saving checkpoint... 
Iteration: 1104600304, states[0] = -51.247284, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1118968317, states[0] = -87.375488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133350234, states[0] = -51.158768, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1149748128, states[0] = -87.416054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165113689, states[0] = -69.442667, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1179702703, states[0] = -87.347960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195077581, states[0] = -23.107559, states[40]= 0.000811
Saving checkpoint... 
Iteration: 1208349893, states[0] = -50.728119, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1222381469, states[0] = -86.639006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235666396, states[0] = -87.262314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248794812, states[0] = 8.124985, states[40]= 0.005784
Saving checkpoint... 
Iteration: 1263935406, states[0] = -87.311225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278355307, states[0] = -57.673494, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1293512217, states[0] = 22.369925, states[40]= 0.029427
Saving checkpoint... 
Iteration: 1309318814, states[0] = -12.190737, states[40]= 0.002260
Saving checkpoint... 
Iteration: 1324359834, states[0] = -63.808412, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1341730328, states[0] = -87.393293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355643901, states[0] = -87.178063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371675885, states[0] = -87.287794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387847447, states[0] = -47.657718, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1406447851, states[0] = -87.338151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421579177, states[0] = -25.102411, states[40]= 0.000684
Saving checkpoint... 
Iteration: 1436505015, states[0] = 26.887585, states[40]= 0.127301


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_500-conf_755.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_500-conf_755_0_r1232907513_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_500-conf_755_0_r1232907513_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 108.630683
     * GNaL_b in INaL: 0.004381
     * Gto_b in Ito: 0.090166
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031859
     * GKs_b in IKs: 0.002046
     * GK1_b in IK1: 0.157248
     * Gncx_b in INaCa_i: 0.000977
     * Pnak_b in INaK: 67.425261
     * GKb_b in IKb: 0.003757
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036494
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1436505015
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 26.887585 (After loading)
 - states[40]: 0.127301 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1451896961, states[0] = -87.196588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469489392, states[0] = -87.405222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487641850, states[0] = -87.159359, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -87.293569
 - CaMKt in component CaMK (millimolar): 0.019126
 - cass in component intracellular_ions (millimolar): 0.000094
 - nai in component intracellular_ions (millimolar): 6.823954
 - nass in component intracellular_ions (millimolar): 6.824054
 - ki in component intracellular_ions (millimolar): 145.134495
 - kss in component intracellular_ions (millimolar): 145.134468
 - cansr in component intracellular_ions (millimolar): 1.419608
 - cajsr in component intracellular_ions (millimolar): 1.204027
 - cai in component intracellular_ions (millimolar): 0.000093
 - m in component INa (dimensionless): 0.007788
 - hf in component INa (dimensionless): 0.677504
 - hs in component INa (dimensionless): 0.677399
 - j in component INa (dimensionless): 0.676700
 - hsp in component INa (dimensionless): 0.430957
 - jp in component INa (dimensionless): 0.674857
 - mL in component INaL (dimensionless): 0.000210
 - hL in component INaL (dimensionless): 0.389065
 - hLp in component INaL (dimensionless): 0.182918
 - a in component Ito (dimensionless): 0.001041
 - iF in component Ito (dimensionless): 0.999506
 - iS in component Ito (dimensionless): 0.296878
 - ap in component Ito (dimensionless): 0.000531
 - iFp in component Ito (dimensionless): 0.999506
 - iSp in component Ito (dimensionless): 0.346064
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.863538
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.991683
 - jca in component ICaL (dimensionless): 0.991846
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004130
 - xrf in component IKr (dimensionless): 0.001572
 - xrs in component IKr (dimensionless): 0.666393
 - xs1 in component IKs (dimensionless): 0.376055
 - xs2 in component IKs (dimensionless): 0.000213
 - xk1 in component IK1 (dimensionless): 0.996911
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:25:20 (979): called boinc_finish(0)

</stderr_txt>
]]>