𝕏

Task 55203480

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-TESZT_Block_Ks_95-conf_649_1
Workunit 26215344
Created 28 Jun 2024, 6:00:20 UTC
Sent 29 Jun 2024, 2:44:08 UTC
Report deadline 2 Jul 2024, 2:44:08 UTC
Received 29 Jun 2024, 15:33:11 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 217006
Run time 5 hours 15 min 12 sec
CPU time 3 hours 15 min 29 sec
Validate state Valid
Credit 46.76
Device peak FLOPS 4.06 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.49 MB
Peak swap size 32.57 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-TESZT_Block_Ks_95-conf_649.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-TESZT_Block_Ks_95-conf_649_1_r802621060_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-TESZT_Block_Ks_95-conf_649_1_r802621060_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 92.714489
     * GNaL_b in INaL: 0.005814
     * Gto_b in Ito: 0.090695
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032233
     * GKs_b in IKs: 0.000103
     * GK1_b in IK1: 0.163347
     * Gncx_b in INaCa_i: 0.000974
     * Pnak_b in INaK: 74.922210
     * GKb_b in IKb: 0.003938
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031075
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 2295908, states[0] = -94.896113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 4741115, states[0] = -94.769772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 7092472, states[0] = -4.974948, states[40]= 0.003451
Saving checkpoint... 
Iteration: 9529552, states[0] = 24.058559, states[40]= 0.002492
Saving checkpoint... 
Iteration: 11824422, states[0] = -94.818588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 14204745, states[0] = -94.532280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16373085, states[0] = -94.835698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 18726825, states[0] = -94.579761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21170613, states[0] = -88.369220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23519649, states[0] = 26.690704, states[40]= 0.002849
Saving checkpoint... 
Iteration: 25834814, states[0] = -94.773507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28258732, states[0] = -94.640555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30694437, states[0] = -94.402986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33066247, states[0] = 11.349151, states[40]= 0.003610
Saving checkpoint... 
Iteration: 35286020, states[0] = -94.689063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37849401, states[0] = -94.772283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39410348, states[0] = -94.814036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41041974, states[0] = 20.744903, states[40]= 0.001815
Saving checkpoint... 
Iteration: 43340038, states[0] = -94.758874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45677666, states[0] = -92.529225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47980084, states[0] = -94.834253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50377315, states[0] = -94.787649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52264122, states[0] = -94.630786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54643692, states[0] = -50.499246, states[40]= 0.000087
Saving checkpoint... 
Iteration: 56837197, states[0] = -94.749554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58984326, states[0] = -94.831019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61351384, states[0] = -94.762457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63706445, states[0] = -94.437306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65885498, states[0] = -94.788176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68345546, states[0] = -94.755050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70787333, states[0] = -94.674289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73335164, states[0] = -94.743106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75696014, states[0] = -94.381584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77844813, states[0] = -94.752498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80351718, states[0] = -94.758788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82753588, states[0] = -94.596320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85224327, states[0] = -94.503667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87401520, states[0] = -94.794181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89896708, states[0] = -94.791132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92293108, states[0] = -94.681469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94631144, states[0] = -37.495314, states[40]= 0.000513
Saving checkpoint... 
Iteration: 96917405, states[0] = -94.801384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99027999, states[0] = 25.262660, states[40]= 0.001300
Saving checkpoint... 
Iteration: 101441362, states[0] = -94.811110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103836107, states[0] = -94.740434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105991973, states[0] = -94.825422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108321296, states[0] = -94.722494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110638466, states[0] = -44.586928, states[40]= 0.000206
Saving checkpoint... 
Iteration: 112759041, states[0] = -94.607792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115228618, states[0] = -94.516395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117419429, states[0] = -94.800936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119666084, states[0] = -76.388855, states[40]= 0.000001
Saving checkpoint... 
Iteration: 122206933, states[0] = -94.432427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124727174, states[0] = -94.510868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127234303, states[0] = -94.535168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129512951, states[0] = 27.257589, states[40]= 0.018271
Saving checkpoint... 
Iteration: 131675154, states[0] = -89.884855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133986969, states[0] = -94.822952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136214841, states[0] = -94.464251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138563272, states[0] = 12.956238, states[40]= 0.003385
Saving checkpoint... 
Iteration: 140767492, states[0] = -94.627147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142835350, states[0] = -94.737848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145069178, states[0] = 10.439310, states[40]= 0.003817
Saving checkpoint... 
Iteration: 147203855, states[0] = -94.418220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149558685, states[0] = 14.802212, states[40]= 0.003027
Saving checkpoint... 
Iteration: 151862347, states[0] = -94.763704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154389998, states[0] = -94.783770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156884579, states[0] = -94.780218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159251808, states[0] = -94.587179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161457464, states[0] = -94.814323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163964470, states[0] = -94.816414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166323871, states[0] = -94.723870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168645778, states[0] = -51.987798, states[40]= 0.000070
Saving checkpoint... 
Iteration: 170815522, states[0] = -94.712879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172887401, states[0] = -94.781828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175088763, states[0] = 0.138267, states[40]= 0.004357
Saving checkpoint... 
Iteration: 177400090, states[0] = -94.789463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179552483, states[0] = 17.173242, states[40]= 0.002548
Saving checkpoint... 
Iteration: 181810689, states[0] = -94.705961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183993538, states[0] = -94.823500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186063458, states[0] = 12.889255, states[40]= 0.003401
Saving checkpoint... 
Iteration: 188359939, states[0] = -94.761161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190710838, states[0] = -94.447274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192717284, states[0] = -94.472871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194941793, states[0] = -94.808569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197140438, states[0] = -46.471876, states[40]= 0.000158
Saving checkpoint... 
Iteration: 199346729, states[0] = -94.748930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201621192, states[0] = -28.044242, states[40]= 0.001147
Saving checkpoint... 
Iteration: 203935471, states[0] = -94.806077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206186758, states[0] = -94.175623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208448968, states[0] = -94.811029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210688196, states[0] = -94.241499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212970845, states[0] = -94.817736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214671663, states[0] = -85.203243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215878087, states[0] = -94.775133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217250139, states[0] = -94.581962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219048069, states[0] = 18.790677, states[40]= 0.002229
Saving checkpoint... 
Iteration: 220944521, states[0] = -94.809381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222420260, states[0] = -94.799444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224410616, states[0] = -94.794749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225861530, states[0] = -94.762240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227616741, states[0] = -23.942154, states[40]= 0.001250
Saving checkpoint... 
Iteration: 229306826, states[0] = -94.699915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231098320, states[0] = -6.922903, states[40]= 0.003256
Saving checkpoint... 
Iteration: 232853878, states[0] = -94.755486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234670342, states[0] = -83.102315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236385945, states[0] = -94.780379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238093247, states[0] = -2.929663, states[40]= 0.004014
Saving checkpoint... 
Iteration: 239804540, states[0] = -94.696379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241533755, states[0] = 23.641658, states[40]= 0.001440
Saving checkpoint... 
Iteration: 243425347, states[0] = -94.801618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245300364, states[0] = -94.689769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247094213, states[0] = -3.645622, states[40]= 0.003899
Saving checkpoint... 
Iteration: 249005385, states[0] = 28.974938, states[40]= 0.227535
Saving checkpoint... 
Iteration: 250965070, states[0] = -94.815889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253097788, states[0] = -6.476689, states[40]= 0.003352
Saving checkpoint... 
Iteration: 254703703, states[0] = -94.416505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256687648, states[0] = -94.218879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258438255, states[0] = -94.806848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260617591, states[0] = -24.724041, states[40]= 0.001243
Saving checkpoint... 
Iteration: 262376827, states[0] = -94.773980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264482665, states[0] = -94.820502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266451552, states[0] = -94.811587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268409004, states[0] = -94.793694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270300531, states[0] = -94.689917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289146170, states[0] = -52.376044, states[40]= 0.000066
Saving checkpoint... 
Iteration: 314672440, states[0] = -86.362612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338939392, states[0] = -94.806926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363787827, states[0] = -94.667587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389151560, states[0] = -58.083638, states[40]= 0.000026
Saving checkpoint... 
Iteration: 414794893, states[0] = -94.679938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438665785, states[0] = -75.773407, states[40]= 0.000001
Saving checkpoint... 
Iteration: 464345926, states[0] = -94.746900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489656713, states[0] = -63.814704, states[40]= 0.000010
Saving checkpoint... 
Iteration: 515328827, states[0] = -94.728107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540610283, states[0] = -17.913326, states[40]= 0.001406
Saving checkpoint... 
Iteration: 564349608, states[0] = -94.750061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588272885, states[0] = -94.636622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613537292, states[0] = 22.517219, states[40]= 0.001593
Saving checkpoint... 
Iteration: 638678532, states[0] = -92.416370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663025649, states[0] = 25.864929, states[40]= 0.001361
Saving checkpoint... 
Iteration: 687311031, states[0] = -94.704112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711220834, states[0] = -94.484042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736064826, states[0] = 12.324781, states[40]= 0.003506
Saving checkpoint... 
Iteration: 759994917, states[0] = -94.821183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783861666, states[0] = -94.759953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808567045, states[0] = 11.382936, states[40]= 0.003670
Saving checkpoint... 
Iteration: 832724075, states[0] = -94.495516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857692482, states[0] = -94.336882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881733752, states[0] = -94.529021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904781258, states[0] = -94.652708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928957031, states[0] = -94.810576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953950796, states[0] = -94.808431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977201734, states[0] = -94.404266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001783850, states[0] = -94.657375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025828984, states[0] = -94.726142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050383986, states[0] = -94.775620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074417206, states[0] = -94.794372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099200709, states[0] = -94.398731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123315871, states[0] = -94.709047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147162595, states[0] = -71.156429, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1172230318, states[0] = -94.516181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194454559, states[0] = -94.808669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218122014, states[0] = -28.792211, states[40]= 0.001109
Saving checkpoint... 
Iteration: 1241925598, states[0] = -94.797503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265825795, states[0] = -94.721285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289965383, states[0] = -94.811595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313452994, states[0] = -94.807657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336763497, states[0] = -94.611902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360501547, states[0] = 45.474255, states[40]= 0.368515
Saving checkpoint... 
Iteration: 1384468749, states[0] = -94.812159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408168822, states[0] = -80.593322, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1431984632, states[0] = -94.816058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456166579, states[0] = -76.987470, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1479636041, states[0] = -42.057151, states[40]= 0.000290
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.695002
 - CaMKt in component CaMK (millimolar): 0.012838
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.658098
 - nass in component intracellular_ions (millimolar): 6.658193
 - ki in component intracellular_ions (millimolar): 145.222391
 - kss in component intracellular_ions (millimolar): 145.222371
 - cansr in component intracellular_ions (millimolar): 1.661237
 - cajsr in component intracellular_ions (millimolar): 1.618321
 - cai in component intracellular_ions (millimolar): 0.000089
 - m in component INa (dimensionless): 0.003695
 - hf in component INa (dimensionless): 0.876365
 - hs in component INa (dimensionless): 0.876357
 - j in component INa (dimensionless): 0.876304
 - hsp in component INa (dimensionless): 0.718994
 - jp in component INa (dimensionless): 0.876268
 - mL in component INaL (dimensionless): 0.000052
 - hL in component INaL (dimensionless): 0.700428
 - hLp in component INaL (dimensionless): 0.434870
 - a in component Ito (dimensionless): 0.000632
 - iF in component Ito (dimensionless): 0.999865
 - iS in component Ito (dimensionless): 0.605180
 - ap in component Ito (dimensionless): 0.000322
 - iFp in component Ito (dimensionless): 0.999865
 - iSp in component Ito (dimensionless): 0.674965
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.912394
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999816
 - jca in component ICaL (dimensionless): 0.999969
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003024
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.369564
 - xs1 in component IKs (dimensionless): 0.276355
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997391
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:31:56 (78824): called boinc_finish(0)

</stderr_txt>
]]>


CoMBA Research Group Logo
University San Jorge Logo

©2024 Universidad San Jorge