𝕏

Task 55195003

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_41_1
Workunit 26211108
Created 28 Jun 2024, 5:56:42 UTC
Sent 29 Jun 2024, 1:30:56 UTC
Report deadline 2 Jul 2024, 4:23:44 UTC
Received 1 Jul 2024, 4:41:54 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 233272
Run time 1 hours 46 min 11 sec
CPU time 1 hours 43 min 27 sec
Validate state Valid
Credit 48.68
Device peak FLOPS 4.73 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.11 MB
Peak swap size 4.35 GB
Peak disk usage 0.06 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_41.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_41_1_r1966067230_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_K1_75-conf_41_1_r1966067230_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 90.710414
     * GNaL_b in INaL: 0.007523
     * Gto_b in Ito: 0.096072
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033385
     * GKs_b in IKs: 0.001950
     * GK1_b in IK1: 0.038884
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 66.814150
     * GKb_b in IKb: 0.003713
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.023799
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9645896, states[0] = -55.464627, states[40]= 0.000023
Saving checkpoint... 
Iteration: 19161711, states[0] = -64.843588, states[40]= 0.000005
Saving checkpoint... 
Iteration: 33345001, states[0] = -90.302496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47614271, states[0] = -23.291642, states[40]= 0.001029
Saving checkpoint... 
Iteration: 62179547, states[0] = -72.459088, states[40]= 0.000001
Saving checkpoint... 
Iteration: 76191895, states[0] = -76.861728, states[40]= 0.000001
Saving checkpoint... 
Iteration: 90705534, states[0] = -80.712730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105484764, states[0] = -90.610585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118706740, states[0] = -80.981982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133182256, states[0] = -73.410518, states[40]= 0.000001
Saving checkpoint... 
Iteration: 147110074, states[0] = -18.936546, states[40]= 0.001150
Saving checkpoint... 
Iteration: 161328588, states[0] = -90.063131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176057734, states[0] = 15.263351, states[40]= 0.001771
Saving checkpoint... 
Iteration: 190081550, states[0] = 4.294307, states[40]= 0.003402
Saving checkpoint... 
Iteration: 201526103, states[0] = 26.162014, states[40]= 0.000702
Saving checkpoint... 
Iteration: 210884073, states[0] = -90.393396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224985125, states[0] = -90.599530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239252935, states[0] = -87.916239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253163847, states[0] = -64.783093, states[40]= 0.000006
Saving checkpoint... 
Iteration: 267109332, states[0] = -18.186245, states[40]= 0.001195
Saving checkpoint... 
Iteration: 281803316, states[0] = -89.754494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296044458, states[0] = 20.350640, states[40]= 0.001044
Saving checkpoint... 
Iteration: 310461796, states[0] = -90.574587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324790206, states[0] = -89.504973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339835873, states[0] = -90.121857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355209250, states[0] = -81.555842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369534573, states[0] = 23.777109, states[40]= 0.000712
Saving checkpoint... 
Iteration: 382719308, states[0] = -83.680327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396744821, states[0] = -87.234135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410295308, states[0] = -89.611822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423763355, states[0] = -88.562789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437745790, states[0] = -87.324406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451290622, states[0] = -89.513320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465413789, states[0] = -90.485010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479443663, states[0] = -90.547141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493562008, states[0] = 13.522701, states[40]= 0.002066
Saving checkpoint... 
Iteration: 508637275, states[0] = -44.553548, states[40]= 0.000173
Saving checkpoint... 
Iteration: 522504715, states[0] = 28.392048, states[40]= 0.293328
Saving checkpoint... 
Iteration: 536230308, states[0] = -85.510775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550003401, states[0] = 31.910824, states[40]= 0.447000
Saving checkpoint... 
Iteration: 563903685, states[0] = -90.456617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577904771, states[0] = -90.459692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592157677, states[0] = -61.007112, states[40]= 0.000012
Saving checkpoint... 
Iteration: 604412555, states[0] = -90.480892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618093146, states[0] = -3.197167, states[40]= 0.003343
Saving checkpoint... 
Iteration: 631844346, states[0] = -90.183084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645881105, states[0] = -90.378160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660799593, states[0] = -89.689389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674854184, states[0] = -90.246015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689414998, states[0] = -90.486566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703832692, states[0] = -90.093003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718642152, states[0] = -48.956455, states[40]= 0.000091
Saving checkpoint... 
Iteration: 733042932, states[0] = 20.906309, states[40]= 0.000981
Saving checkpoint... 
Iteration: 747660333, states[0] = -62.697015, states[40]= 0.000009
Saving checkpoint... 
Iteration: 762097931, states[0] = -7.150749, states[40]= 0.002772
Saving checkpoint... 
Iteration: 776398162, states[0] = -90.438305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790162089, states[0] = -63.758695, states[40]= 0.000007
Saving checkpoint... 
Iteration: 804166823, states[0] = -66.415916, states[40]= 0.000004
Saving checkpoint... 
Iteration: 818262423, states[0] = -88.509900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831791164, states[0] = -89.522416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846642988, states[0] = -49.691094, states[40]= 0.000082
Saving checkpoint... 
Iteration: 861730946, states[0] = -85.599048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876577727, states[0] = 6.336703, states[40]= 0.003193
Saving checkpoint... 
Iteration: 890526337, states[0] = 26.109218, states[40]= 0.000691
Saving checkpoint... 
Iteration: 904587809, states[0] = 0.558287, states[40]= 0.003554
Saving checkpoint... 
Iteration: 919991018, states[0] = -90.599076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934716620, states[0] = -83.150749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949977554, states[0] = -90.587560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964981502, states[0] = -90.591085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980548957, states[0] = 18.678222, states[40]= 0.001255
Saving checkpoint... 
Iteration: 995578865, states[0] = 5.746218, states[40]= 0.003261
Saving checkpoint... 
Iteration: 1010864715, states[0] = -90.301560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021168980, states[0] = -67.533715, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1036669554, states[0] = -67.822427, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1051415531, states[0] = -90.485465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066925427, states[0] = -90.508417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082245957, states[0] = -87.333692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097510815, states[0] = 26.942585, states[40]= 0.036787
Saving checkpoint... 
Iteration: 1112521901, states[0] = 26.989987, states[40]= 0.001249
Saving checkpoint... 
Iteration: 1127606679, states[0] = -15.542607, states[40]= 0.001427
Saving checkpoint... 
Iteration: 1142709441, states[0] = -81.593390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158181920, states[0] = -73.256582, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1173460436, states[0] = -90.567057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189328995, states[0] = -90.057041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205195514, states[0] = -77.892424, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1220864156, states[0] = -90.297271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236457717, states[0] = -90.563081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252360707, states[0] = -90.278947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267979002, states[0] = -90.586795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283398389, states[0] = -90.435598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299555174, states[0] = 16.283689, states[40]= 0.001607
Saving checkpoint... 
Iteration: 1315077512, states[0] = 6.447966, states[40]= 0.003179
Saving checkpoint... 
Iteration: 1331061439, states[0] = 13.759987, states[40]= 0.002025
Saving checkpoint... 
Iteration: 1346500396, states[0] = -40.466996, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1362397788, states[0] = -90.433154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378253687, states[0] = -87.959860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394182195, states[0] = -73.361020, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1409557798, states[0] = 15.242167, states[40]= 0.001775
Saving checkpoint... 
Iteration: 1424877846, states[0] = -90.359461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440285367, states[0] = -89.378668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455387869, states[0] = -90.398605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471432102, states[0] = -90.519520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487034429, states[0] = 23.825001, states[40]= 0.000708
Saving checkpoint... 
Iteration: 1502150897, states[0] = 6.783008, states[40]= 0.007047
Saving checkpoint... 
Iteration: 1517516530, states[0] = 8.506449, states[40]= 0.001496
Saving checkpoint... 
Iteration: 1532504877, states[0] = -88.443857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1546755931, states[0] = 25.716472, states[40]= 0.204681
Saving checkpoint... 
Iteration: 1561501769, states[0] = -89.065578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1576799207, states[0] = -88.690628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1586621472, states[0] = -88.006203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1601309796, states[0] = -84.372829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1616268896, states[0] = -80.436486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1630659611, states[0] = -86.588598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1640864086, states[0] = -86.021964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1655930122, states[0] = -85.604887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1670245824, states[0] = -74.397355, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1679882209, states[0] = -81.555948, states[40]= 0.000001
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -81.058154
 - CaMKt in component CaMK (millimolar): 0.001094
 - cass in component intracellular_ions (millimolar): 0.000084
 - nai in component intracellular_ions (millimolar): 6.258576
 - nass in component intracellular_ions (millimolar): 6.258658
 - ki in component intracellular_ions (millimolar): 145.636286
 - kss in component intracellular_ions (millimolar): 145.636272
 - cansr in component intracellular_ions (millimolar): 1.520074
 - cajsr in component intracellular_ions (millimolar): 1.520306
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.014549
 - hf in component INa (dimensionless): 0.429914
 - hs in component INa (dimensionless): 0.430278
 - j in component INa (dimensionless): 0.431733
 - hsp in component INa (dimensionless): 0.214773
 - jp in component INa (dimensionless): 0.432557
 - mL in component INaL (dimensionless): 0.000687
 - hL in component INaL (dimensionless): 0.306385
 - hLp in component INaL (dimensionless): 0.171913
 - a in component Ito (dimensionless): 0.001585
 - iF in component Ito (dimensionless): 0.998533
 - iS in component Ito (dimensionless): 0.992920
 - ap in component Ito (dimensionless): 0.000808
 - iFp in component Ito (dimensionless): 0.998533
 - iSp in component Ito (dimensionless): 0.995351
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998826
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002642
 - xrf in component IKr (dimensionless): 0.000022
 - xrs in component IKr (dimensionless): 0.014442
 - xs1 in component IKs (dimensionless): 0.025123
 - xs2 in component IKs (dimensionless): 0.000411
 - xk1 in component IK1 (dimensionless): 0.999322
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
00:41:42 (99882): called boinc_finish(0)

</stderr_txt>
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