𝕏

Task 55191727

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-BASE_ENDO-conf_138_0
Workunit 26209475
Created 28 Jun 2024, 5:55:17 UTC
Sent 29 Jun 2024, 1:05:56 UTC
Report deadline 2 Jul 2024, 1:05:56 UTC
Received 29 Jun 2024, 9:25:21 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 233203
Run time 3 hours 6 min 33 sec
CPU time 2 hours 58 min 17 sec
Validate state Valid
Credit 41.76
Device peak FLOPS 3.95 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.66 MB
Peak swap size 5.25 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-BASE_ENDO-conf_138.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-BASE_ENDO-conf_138_0_r1474305430_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-BASE_ENDO-conf_138_0_r1474305430_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 114.288367
     * GNaL_b in INaL: 0.005822
     * Gto_b in Ito: 0.082147
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031999
     * GKs_b in IKs: 0.001930
     * GK1_b in IK1: 0.164951
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 68.872351
     * GKb_b in IKb: 0.003736
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.020401
     * celltype in environment: 0.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8763813, states[0] = -86.875676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17604364, states[0] = -20.539848, states[40]= 0.001021
Saving checkpoint... 
Iteration: 26429323, states[0] = -86.951098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34990494, states[0] = -86.956882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43701269, states[0] = -86.520973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52133609, states[0] = -49.451641, states[40]= 0.000073
Saving checkpoint... 
Iteration: 61072849, states[0] = 7.387029, states[40]= 0.003543
Saving checkpoint... 
Iteration: 69832992, states[0] = -86.842033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78431455, states[0] = -86.912899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87351125, states[0] = -86.857203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95765711, states[0] = -86.720309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104280848, states[0] = -86.752956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112950401, states[0] = -86.914995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121782302, states[0] = -86.754308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130570875, states[0] = 8.590790, states[40]= 0.003457
Saving checkpoint... 
Iteration: 139012540, states[0] = 28.659125, states[40]= 0.019383
Saving checkpoint... 
Iteration: 147899112, states[0] = -86.888889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156875015, states[0] = -86.872195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165623884, states[0] = -38.235145, states[40]= 0.000339
Saving checkpoint... 
Iteration: 174212172, states[0] = -86.542691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183070667, states[0] = 8.717054, states[40]= 0.003448
Saving checkpoint... 
Iteration: 191795884, states[0] = -86.777562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200575100, states[0] = 6.407128, states[40]= 0.003708
Saving checkpoint... 
Iteration: 209437721, states[0] = -86.906937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218301947, states[0] = -86.787550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227147969, states[0] = -65.056211, states[40]= 0.000006
Saving checkpoint... 
Iteration: 235804413, states[0] = -86.791406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244613758, states[0] = -27.654739, states[40]= 0.000839
Saving checkpoint... 
Iteration: 253368299, states[0] = -86.865657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262026997, states[0] = 26.381181, states[40]= 0.001031
Saving checkpoint... 
Iteration: 270781093, states[0] = -86.748913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279893452, states[0] = -86.883752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288795482, states[0] = -86.776143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297587255, states[0] = -1.245727, states[40]= 0.003799
Saving checkpoint... 
Iteration: 306439179, states[0] = -86.906928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315331530, states[0] = -86.828629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324080305, states[0] = 3.422825, states[40]= 0.003903
Saving checkpoint... 
Iteration: 332819584, states[0] = -86.813275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341700351, states[0] = -86.490595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350652779, states[0] = -71.448049, states[40]= 0.000002
Saving checkpoint... 
Iteration: 359443124, states[0] = -86.908233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368298005, states[0] = -86.780144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377159209, states[0] = -79.945266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385978328, states[0] = -86.919469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394905437, states[0] = -86.890406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403781452, states[0] = -86.749022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412660880, states[0] = -81.672138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421515725, states[0] = 28.612220, states[40]= 0.006965
Saving checkpoint... 
Iteration: 430434120, states[0] = -86.904289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439229987, states[0] = -86.608924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448044007, states[0] = 20.280327, states[40]= 0.001581
Saving checkpoint... 
Iteration: 456841723, states[0] = -86.839600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465436875, states[0] = -86.905279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474316693, states[0] = -86.808646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483103365, states[0] = -16.605552, states[40]= 0.001355
Saving checkpoint... 
Iteration: 491593805, states[0] = -6.736866, states[40]= 0.003018
Saving checkpoint... 
Iteration: 500271325, states[0] = -86.726747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509032474, states[0] = 24.609649, states[40]= 0.001086
Saving checkpoint... 
Iteration: 517831706, states[0] = -86.827930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526671144, states[0] = -85.980229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535521159, states[0] = 27.859908, states[40]= 0.001741
Saving checkpoint... 
Iteration: 544375666, states[0] = -86.870148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553224966, states[0] = -86.590366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562013186, states[0] = 28.679770, states[40]= 0.015662
Saving checkpoint... 
Iteration: 570739794, states[0] = -86.641103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579564144, states[0] = 11.840419, states[40]= 0.002987
Saving checkpoint... 
Iteration: 588459864, states[0] = -86.913134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597278509, states[0] = -86.742051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606182297, states[0] = -86.388545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615025391, states[0] = 26.840216, states[40]= 0.001086
Saving checkpoint... 
Iteration: 623686347, states[0] = -86.419400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632468893, states[0] = -86.915730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641348198, states[0] = -86.845541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650094398, states[0] = -7.295639, states[40]= 0.002912
Saving checkpoint... 
Iteration: 658882449, states[0] = -86.874637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667512506, states[0] = 28.666189, states[40]= 0.019596
Saving checkpoint... 
Iteration: 676389910, states[0] = -86.879674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685167896, states[0] = -85.453758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694128350, states[0] = -42.899743, states[40]= 0.000187
Saving checkpoint... 
Iteration: 702849084, states[0] = -86.846158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711676269, states[0] = -86.284426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720401433, states[0] = -86.886657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729216043, states[0] = -86.555362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737999562, states[0] = -86.922977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746837928, states[0] = -86.834129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755589102, states[0] = -2.666922, states[40]= 0.003657
Saving checkpoint... 
Iteration: 764474297, states[0] = -86.916694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773250751, states[0] = -86.673120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782203543, states[0] = -86.502750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791003516, states[0] = 33.487388, states[40]= 0.392446
Saving checkpoint... 
Iteration: 799785016, states[0] = -86.754387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808480977, states[0] = -86.918295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817303862, states[0] = -86.787844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826098909, states[0] = -11.834758, states[40]= 0.002043
Saving checkpoint... 
Iteration: 834889600, states[0] = -86.878766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843701827, states[0] = -86.494897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852611001, states[0] = -24.757280, states[40]= 0.000926
Saving checkpoint... 
Iteration: 861325974, states[0] = -86.819322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870045253, states[0] = 19.788491, states[40]= 0.001652
Saving checkpoint... 
Iteration: 878925673, states[0] = -86.898580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887894656, states[0] = -86.881794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896875166, states[0] = -86.868200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905672028, states[0] = -86.061445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914426848, states[0] = -86.898960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923182660, states[0] = -86.390471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931890574, states[0] = -86.878977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940505395, states[0] = 29.762436, states[40]= 0.214599
Saving checkpoint... 
Iteration: 949336715, states[0] = -86.831857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958122841, states[0] = -37.111905, states[40]= 0.000386
Saving checkpoint... 
Iteration: 966745402, states[0] = -86.656641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975542185, states[0] = 20.995284, states[40]= 0.001483
Saving checkpoint... 
Iteration: 984332302, states[0] = -86.826564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993156252, states[0] = -76.229708, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1001843033, states[0] = -86.838579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010662401, states[0] = -82.940671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019391091, states[0] = -86.878927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028164037, states[0] = -83.998216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036873624, states[0] = -86.866387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045763166, states[0] = -86.704886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054508591, states[0] = 28.523487, states[40]= 0.073001
Saving checkpoint... 
Iteration: 1063241540, states[0] = -86.644383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072060915, states[0] = 13.288902, states[40]= 0.002742
Saving checkpoint... 
Iteration: 1080883463, states[0] = -86.873482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089719130, states[0] = -86.565872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098373686, states[0] = -86.866162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107263650, states[0] = -86.705810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115945904, states[0] = -86.905934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124824859, states[0] = -86.816721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133636406, states[0] = -51.584815, states[40]= 0.000054
Saving checkpoint... 
Iteration: 1142413621, states[0] = -86.891521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151033081, states[0] = 24.398636, states[40]= 0.001103
Saving checkpoint... 
Iteration: 1159764286, states[0] = -86.707141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168568533, states[0] = 9.777769, states[40]= 0.003305
Saving checkpoint... 
Iteration: 1177389222, states[0] = -86.876995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186329815, states[0] = -86.822664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195141700, states[0] = -57.509951, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1203943266, states[0] = -86.904544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212882620, states[0] = -86.872299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221466032, states[0] = -86.912265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230436162, states[0] = -86.901596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239284708, states[0] = -86.751814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248196794, states[0] = -86.470274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257065189, states[0] = 11.361448, states[40]= 0.003064
Saving checkpoint... 
Iteration: 1265871924, states[0] = -86.864035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274665465, states[0] = -84.680399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283444928, states[0] = -86.904825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291844064, states[0] = -86.838381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300695338, states[0] = -86.463252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309528706, states[0] = 25.861405, states[40]= 0.001019
Saving checkpoint... 
Iteration: 1318397423, states[0] = -86.881600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327368455, states[0] = -86.860964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336198179, states[0] = -86.476237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345081238, states[0] = 2.851471, states[40]= 0.003918
Saving checkpoint... 
Iteration: 1353860237, states[0] = -86.853810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362575142, states[0] = 6.391348, states[40]= 0.003710
Saving checkpoint... 
Iteration: 1371385403, states[0] = -86.873546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380181585, states[0] = -86.377745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388959749, states[0] = -86.909551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397748758, states[0] = -86.664595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406536407, states[0] = 23.197374, states[40]= 0.001219
Saving checkpoint... 
Iteration: 1415260998, states[0] = -86.697775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424158969, states[0] = -79.654536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432891491, states[0] = -86.877352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441793085, states[0] = -86.766706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450717959, states[0] = -86.559668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459595091, states[0] = -7.957529, states[40]= 0.002784
Saving checkpoint... 
Iteration: 1468485884, states[0] = -86.916613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477372348, states[0] = -86.863430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486221105, states[0] = -86.571675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495184780, states[0] = -86.404909, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.795573
 - CaMKt in component CaMK (millimolar): 0.012171
 - cass in component intracellular_ions (millimolar): 0.000086
 - nai in component intracellular_ions (millimolar): 6.603920
 - nass in component intracellular_ions (millimolar): 6.604012
 - ki in component intracellular_ions (millimolar): 145.281898
 - kss in component intracellular_ions (millimolar): 145.281876
 - cansr in component intracellular_ions (millimolar): 1.629415
 - cajsr in component intracellular_ions (millimolar): 1.586460
 - cai in component intracellular_ions (millimolar): 0.000088
 - m in component INa (dimensionless): 0.008188
 - hf in component INa (dimensionless): 0.659368
 - hs in component INa (dimensionless): 0.659348
 - j in component INa (dimensionless): 0.659234
 - hsp in component INa (dimensionless): 0.411313
 - jp in component INa (dimensionless): 0.659154
 - mL in component INaL (dimensionless): 0.000231
 - hL in component INaL (dimensionless): 0.462734
 - hLp in component INaL (dimensionless): 0.235955
 - a in component Ito (dimensionless): 0.001077
 - iF in component Ito (dimensionless): 0.999461
 - iS in component Ito (dimensionless): 0.570191
 - ap in component Ito (dimensionless): 0.000549
 - iFp in component Ito (dimensionless): 0.999461
 - iSp in component Ito (dimensionless): 0.619821
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.915866
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999839
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002901
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.462062
 - xs1 in component IKs (dimensionless): 0.269310
 - xs2 in component IKs (dimensionless): 0.000218
 - xk1 in component IK1 (dimensionless): 0.997032
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:24:36 (8112): called boinc_finish(0)

</stderr_txt>
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