𝕏

Task 55184459

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_931_1
Workunit 26205844
Created 28 Jun 2024, 5:52:06 UTC
Sent 29 Jun 2024, 0:02:51 UTC
Report deadline 2 Jul 2024, 2:55:39 UTC
Received 1 Jul 2024, 18:23:12 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 223892
Run time 46 min 56 sec
CPU time 42 min
Validate state Valid
Credit 50.46
Device peak FLOPS 5.05 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.56 MB
Peak swap size 391.76 GB
Peak disk usage 0.07 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_931.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_931_1_r2053969280_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_931_1_r2053969280_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 114.775016
     * GNaL_b in INaL: 0.004804
     * Gto_b in Ito: 0.072830
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033969
     * GKs_b in IKs: 0.000106
     * GK1_b in IK1: 0.181482
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 66.824872
     * GKb_b in IKb: 0.003900
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.041910
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12828962, states[0] = -94.871446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25301002, states[0] = -94.815465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35196105, states[0] = -94.562999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46175812, states[0] = -94.450791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56092058, states[0] = -8.567149, states[40]= 0.003133
Saving checkpoint... 
Iteration: 66128548, states[0] = -46.301781, states[40]= 0.000142
Saving checkpoint... 
Iteration: 74558679, states[0] = 12.668425, states[40]= 0.004526
Saving checkpoint... 
Iteration: 83472538, states[0] = -94.909341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92491090, states[0] = -94.913120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101114057, states[0] = -31.117280, states[40]= 0.000836
Saving checkpoint... 
Iteration: 112883778, states[0] = -94.877866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122243090, states[0] = -94.704106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130899561, states[0] = -94.885795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139226732, states[0] = -94.661004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151254706, states[0] = -94.730366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162164767, states[0] = -93.314183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173050452, states[0] = 16.227004, states[40]= 0.003931
Saving checkpoint... 
Iteration: 183254378, states[0] = -94.729612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192293741, states[0] = -94.797510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200496024, states[0] = -94.914035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208991082, states[0] = -94.913146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219357314, states[0] = -94.861313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228684499, states[0] = -94.510973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238968046, states[0] = -94.908360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249696932, states[0] = -94.561157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260256894, states[0] = -94.734663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268300793, states[0] = -94.806665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276440625, states[0] = -94.900966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285776828, states[0] = -94.771585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294086410, states[0] = -3.592557, states[40]= 0.004286
Saving checkpoint... 
Iteration: 302797339, states[0] = -94.802049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314120757, states[0] = -38.045479, states[40]= 0.000421
Saving checkpoint... 
Iteration: 325084136, states[0] = -1.804128, states[40]= 0.004608
Saving checkpoint... 
Iteration: 334923349, states[0] = -94.895029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345419227, states[0] = -94.893468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354289040, states[0] = -94.790346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362372502, states[0] = -94.870828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372097066, states[0] = -13.650351, states[40]= 0.002025
Saving checkpoint... 
Iteration: 381652534, states[0] = -77.175457, states[40]= 0.000001
Saving checkpoint... 
Iteration: 390716830, states[0] = -94.630305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402070514, states[0] = 6.819080, states[40]= 0.005076
Saving checkpoint... 
Iteration: 412338660, states[0] = -94.846130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422407128, states[0] = -94.888353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430997379, states[0] = -94.913540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439535570, states[0] = 22.076135, states[40]= 0.002864
Saving checkpoint... 
Iteration: 448216318, states[0] = -94.628483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458604765, states[0] = -21.641789, states[40]= 0.001220
Saving checkpoint... 
Iteration: 471471077, states[0] = -94.908302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482327100, states[0] = -94.835354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492442807, states[0] = -94.900928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502665652, states[0] = -93.596730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512304279, states[0] = -94.810259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523364447, states[0] = -94.865215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534705667, states[0] = -94.592299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545042390, states[0] = 19.481420, states[40]= 0.003321
Saving checkpoint... 
Iteration: 554887193, states[0] = -94.878488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564734489, states[0] = -94.681125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574040843, states[0] = 20.083549, states[40]= 0.003210
Saving checkpoint... 
Iteration: 583912012, states[0] = -94.889869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594264175, states[0] = -94.748048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602266947, states[0] = -94.753231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610322242, states[0] = -94.830112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620806578, states[0] = -94.812709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628421590, states[0] = -94.893440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637226391, states[0] = -94.658506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646824566, states[0] = -94.832335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656516931, states[0] = 27.598028, states[40]= 0.006489
Saving checkpoint... 
Iteration: 666576076, states[0] = 3.637350, states[40]= 0.005105
Saving checkpoint... 
Iteration: 676609634, states[0] = -26.624184, states[40]= 0.001067
Saving checkpoint... 
Iteration: 683986828, states[0] = -94.910846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691277634, states[0] = -94.771604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701330427, states[0] = -94.837814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709090754, states[0] = -7.389434, states[40]= 0.003422
Saving checkpoint... 
Iteration: 720103154, states[0] = -19.977314, states[40]= 0.001296
Saving checkpoint... 
Iteration: 730856498, states[0] = -94.859091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741994429, states[0] = -94.912034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751648037, states[0] = -69.885754, states[40]= 0.000004
Saving checkpoint... 
Iteration: 762396411, states[0] = -94.882419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771878489, states[0] = -94.873031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780391796, states[0] = -94.880111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788952501, states[0] = -94.902721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797751736, states[0] = -94.721944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808378132, states[0] = -94.872709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818190151, states[0] = -94.532834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829088820, states[0] = -5.635999, states[40]= 0.003842
Saving checkpoint... 
Iteration: 838090137, states[0] = -6.819293, states[40]= 0.003561
Saving checkpoint... 
Iteration: 848996216, states[0] = -94.911997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859143894, states[0] = -64.191025, states[40]= 0.000009
Saving checkpoint... 
Iteration: 868985632, states[0] = -94.910024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879845371, states[0] = -94.850188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888904149, states[0] = -94.885556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897906002, states[0] = -94.886336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905346920, states[0] = -94.851337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914956796, states[0] = -94.903448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926079697, states[0] = 1.342270, states[40]= 0.004986
Saving checkpoint... 
Iteration: 936404702, states[0] = -94.885646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947842288, states[0] = -94.847458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958970198, states[0] = -94.906535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969009347, states[0] = 28.910490, states[40]= 0.059896
Saving checkpoint... 
Iteration: 978371847, states[0] = -94.868441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989091168, states[0] = -7.776138, states[40]= 0.003327
Saving checkpoint... 
Iteration: 999534002, states[0] = 22.648051, states[40]= 0.002774
Saving checkpoint... 
Iteration: 1010029170, states[0] = 24.324349, states[40]= 0.002565
Saving checkpoint... 
Iteration: 1020163236, states[0] = -92.606763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030842173, states[0] = -94.847095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041011197, states[0] = 28.500739, states[40]= 0.033016
Saving checkpoint... 
Iteration: 1050907817, states[0] = -94.886620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060828943, states[0] = -94.835253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071628633, states[0] = -46.458103, states[40]= 0.000139
Saving checkpoint... 
Iteration: 1082281616, states[0] = -94.776750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092493425, states[0] = -94.910730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102697108, states[0] = -94.559039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112684885, states[0] = -94.509809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122242384, states[0] = -94.699322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133001466, states[0] = 49.777609, states[40]= 0.276928
Saving checkpoint... 
Iteration: 1143299937, states[0] = -94.802734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153069247, states[0] = 7.498472, states[40]= 0.005043
Saving checkpoint... 
Iteration: 1161111753, states[0] = -28.783194, states[40]= 0.000970
Saving checkpoint... 
Iteration: 1170145832, states[0] = -66.756686, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1180406785, states[0] = -94.885762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190336110, states[0] = -94.841397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201461140, states[0] = -94.903621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209353396, states[0] = -94.855294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218956132, states[0] = -94.902297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228026301, states[0] = 25.241428, states[40]= 0.002544
Saving checkpoint... 
Iteration: 1238069624, states[0] = 7.298384, states[40]= 0.005054
Saving checkpoint... 
Iteration: 1247293855, states[0] = -94.794274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258813793, states[0] = -94.819005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268414171, states[0] = -94.888531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279004229, states[0] = 35.281116, states[40]= 0.307423
Saving checkpoint... 
Iteration: 1288172581, states[0] = -94.378718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298899828, states[0] = -94.882289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308495014, states[0] = -94.910311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316184534, states[0] = -94.507569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325300824, states[0] = -94.803286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334717726, states[0] = -94.630065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344125488, states[0] = -43.044471, states[40]= 0.000223
Saving checkpoint... 
Iteration: 1353933865, states[0] = -94.895364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363088247, states[0] = -5.134123, states[40]= 0.003956
Saving checkpoint... 
Iteration: 1371555701, states[0] = 13.984316, states[40]= 0.004320
Saving checkpoint... 
Iteration: 1378090320, states[0] = -6.985686, states[40]= 0.003520
Saving checkpoint... 
Iteration: 1386319380, states[0] = -94.824640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395958540, states[0] = -94.902344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405516234, states[0] = 27.724357, states[40]= 0.007662
Saving checkpoint... 
Iteration: 1411918378, states[0] = -94.889708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420779261, states[0] = -94.771893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430991504, states[0] = -94.909300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440136432, states[0] = -55.200837, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1448386065, states[0] = -94.875012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458479900, states[0] = -94.906997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468415279, states[0] = -94.888325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477961842, states[0] = -94.902903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485771709, states[0] = -94.758952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494283003, states[0] = -94.777584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1502181428, states[0] = -33.656126, states[40]= 0.000563
Saving checkpoint... 
Iteration: 1511125204, states[0] = -67.167439, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1519511254, states[0] = -95.007165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1527163818, states[0] = -94.899469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1536820998, states[0] = -94.821665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1548509075, states[0] = -94.580694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1558132731, states[0] = -41.420935, states[40]= 0.000297
Saving checkpoint... 
Iteration: 1568871562, states[0] = -94.715276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1577938862, states[0] = -94.705684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1586489986, states[0] = -94.605731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1595535990, states[0] = -94.607493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1604000222, states[0] = -67.327646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1611870199, states[0] = -94.526212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1621550393, states[0] = -94.542214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1631896268, states[0] = -94.531360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1640865507, states[0] = -94.540014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649439382, states[0] = -94.522343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1657946563, states[0] = -94.489914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1666444894, states[0] = -94.521984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1676210477, states[0] = -94.523379, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.386953
 - CaMKt in component CaMK (millimolar): 0.001117
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.531691
 - nass in component intracellular_ions (millimolar): 6.531778
 - ki in component intracellular_ions (millimolar): 145.370829
 - kss in component intracellular_ions (millimolar): 145.370818
 - cansr in component intracellular_ions (millimolar): 1.567702
 - cajsr in component intracellular_ions (millimolar): 1.567674
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003812
 - hf in component INa (dimensionless): 0.870774
 - hs in component INa (dimensionless): 0.870774
 - j in component INa (dimensionless): 0.870775
 - hsp in component INa (dimensionless): 0.708703
 - jp in component INa (dimensionless): 0.870775
 - mL in component INaL (dimensionless): 0.000055
 - hL in component INaL (dimensionless): 0.715382
 - hLp in component INaL (dimensionless): 0.523338
 - a in component Ito (dimensionless): 0.000645
 - iF in component Ito (dimensionless): 0.999857
 - iS in component Ito (dimensionless): 0.997837
 - ap in component Ito (dimensionless): 0.000329
 - iFp in component Ito (dimensionless): 0.999857
 - iSp in component Ito (dimensionless): 0.999291
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998972
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003017
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001707
 - xs1 in component IKs (dimensionless): 0.021196
 - xs2 in component IKs (dimensionless): 0.000093
 - xk1 in component IK1 (dimensionless): 0.997469
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
14:23:00 (89385): called boinc_finish(0)

</stderr_txt>
]]>


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