𝕏

Task 55172137

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_3000-conf_19_0
Workunit 26199686
Created 28 Jun 2024, 5:46:33 UTC
Sent 28 Jun 2024, 21:47:03 UTC
Report deadline 1 Jul 2024, 21:47:03 UTC
Received 1 Jul 2024, 13:25:16 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214250
Run time 3 hours 3 min 18 sec
CPU time 2 hours 21 min 6 sec
Validate state Valid
Credit 43.93
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.15 MB
Peak swap size 6.23 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_3000-conf_19.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_3000-conf_19_0_r1563196930_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_3000-conf_19_0_r1563196930_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 107.417585
     * GNaL_b in INaL: 0.006505
     * Gto_b in Ito: 0.084128
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.029652
     * GKs_b in IKs: 0.001759
     * GK1_b in IK1: 0.165974
     * Gncx_b in INaCa_i: 0.000972
     * Pnak_b in INaK: 68.083405
     * GKb_b in IKb: 0.003786
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.026227
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8183102, states[0] = -94.177821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17934659, states[0] = -94.191881, states[40]= 0.000001
Saving checkpoint... 
Iteration: 27620930, states[0] = -94.093295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38332050, states[0] = -94.226791, states[40]= 0.000001
Saving checkpoint... 
Iteration: 46346865, states[0] = -94.211917, states[40]= 0.000001
Saving checkpoint... 
Iteration: 54962707, states[0] = -94.244866, states[40]= 0.000001
Saving checkpoint... 
Iteration: 63847119, states[0] = -94.249350, states[40]= 0.000001
Saving checkpoint... 
Iteration: 73365134, states[0] = -94.226278, states[40]= 0.000001
Saving checkpoint... 
Iteration: 83231755, states[0] = -94.234404, states[40]= 0.000001
Saving checkpoint... 
Iteration: 92511081, states[0] = -94.262119, states[40]= 0.000001
Saving checkpoint... 
Iteration: 100660797, states[0] = -8.964226, states[40]= 0.002615
Saving checkpoint... 
Iteration: 108974110, states[0] = -94.268710, states[40]= 0.000001
Saving checkpoint... 
Iteration: 118512288, states[0] = 30.731340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127601213, states[0] = 14.919696, states[40]= 0.000069
Saving checkpoint... 
Iteration: 136277530, states[0] = -94.248607, states[40]= 0.000001
Saving checkpoint... 
Iteration: 145321651, states[0] = -94.245451, states[40]= 0.000001
Saving checkpoint... 
Iteration: 153411454, states[0] = -36.552708, states[40]= 0.006903
Saving checkpoint... 
Iteration: 162944592, states[0] = -94.276295, states[40]= 0.000001
Saving checkpoint... 
Iteration: 170928526, states[0] = -94.237457, states[40]= 0.000001
Saving checkpoint... 
Iteration: 180122496, states[0] = 6.760702, states[40]= 0.000497
Saving checkpoint... 
Iteration: 188499298, states[0] = -94.274370, states[40]= 0.000001
Saving checkpoint... 
Iteration: 197862900, states[0] = -94.243315, states[40]= 0.000001
Saving checkpoint... 
Iteration: 208868112, states[0] = -18.163767, states[40]= 0.007542
Saving checkpoint... 
Iteration: 217339950, states[0] = -94.245244, states[40]= 0.000001
Saving checkpoint... 
Iteration: 225891932, states[0] = -94.277611, states[40]= 0.000001
Saving checkpoint... 
Iteration: 234946684, states[0] = -94.276823, states[40]= 0.000001
Saving checkpoint... 
Iteration: 244240624, states[0] = -94.253845, states[40]= 0.000001
Saving checkpoint... 
Iteration: 253174424, states[0] = -94.259756, states[40]= 0.000001
Saving checkpoint... 
Iteration: 262244240, states[0] = -94.253178, states[40]= 0.000001
Saving checkpoint... 
Iteration: 270804714, states[0] = -94.270129, states[40]= 0.000001
Saving checkpoint... 
Iteration: 279267981, states[0] = 34.436973, states[40]= 0.008893
Saving checkpoint... 
Iteration: 287662876, states[0] = -94.260112, states[40]= 0.000001
Saving checkpoint... 
Iteration: 297625252, states[0] = -94.156158, states[40]= 0.000001
Saving checkpoint... 
Iteration: 306233619, states[0] = -24.436212, states[40]= 0.021268
Saving checkpoint... 
Iteration: 314255551, states[0] = -94.257515, states[40]= 0.000001
Saving checkpoint... 
Iteration: 322927680, states[0] = -45.314981, states[40]= 0.002510
Saving checkpoint... 
Iteration: 331901834, states[0] = -32.070281, states[40]= 0.010915
Saving checkpoint... 
Iteration: 340504927, states[0] = 23.857142, states[40]= 0.000001
Saving checkpoint... 
Iteration: 348818767, states[0] = -94.270476, states[40]= 0.000001
Saving checkpoint... 
Iteration: 357990783, states[0] = -94.272237, states[40]= 0.000001
Saving checkpoint... 
Iteration: 367226871, states[0] = -94.252454, states[40]= 0.000001
Saving checkpoint... 
Iteration: 376802883, states[0] = 19.174232, states[40]= 0.012752
Saving checkpoint... 
Iteration: 386364865, states[0] = -94.273536, states[40]= 0.000001
Saving checkpoint... 
Iteration: 395467098, states[0] = -94.272589, states[40]= 0.000001
Saving checkpoint... 
Iteration: 404692170, states[0] = -94.254747, states[40]= 0.000001
Saving checkpoint... 
Iteration: 413188846, states[0] = -94.221688, states[40]= 0.000001
Saving checkpoint... 
Iteration: 422145889, states[0] = -94.181017, states[40]= 0.000001
Saving checkpoint... 
Iteration: 431813681, states[0] = -94.243038, states[40]= 0.000001
Saving checkpoint... 
Iteration: 440295846, states[0] = -94.264679, states[40]= 0.000001
Saving checkpoint... 
Iteration: 450088016, states[0] = 19.565969, states[40]= 0.000020
Saving checkpoint... 
Iteration: 459244992, states[0] = -18.119257, states[40]= 0.032040
Saving checkpoint... 
Iteration: 469294875, states[0] = -94.243830, states[40]= 0.000001
Saving checkpoint... 
Iteration: 478234449, states[0] = -94.249114, states[40]= 0.000001
Saving checkpoint... 
Iteration: 488031095, states[0] = -93.884789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496089972, states[0] = -94.261651, states[40]= 0.000001
Saving checkpoint... 
Iteration: 504900714, states[0] = -94.271572, states[40]= 0.000001
Saving checkpoint... 
Iteration: 513239426, states[0] = -22.473880, states[40]= 0.024610
Saving checkpoint... 
Iteration: 522366037, states[0] = -16.797192, states[40]= 0.006401
Saving checkpoint... 
Iteration: 531409034, states[0] = -35.177154, states[40]= 0.008062
Saving checkpoint... 
Iteration: 540398068, states[0] = -30.561706, states[40]= 0.012437
Saving checkpoint... 
Iteration: 549020404, states[0] = 33.184282, states[40]= -0.000000
Saving checkpoint... 
Iteration: 557603409, states[0] = -94.259023, states[40]= 0.000001
Saving checkpoint... 
Iteration: 567914156, states[0] = -94.270015, states[40]= 0.000001
Saving checkpoint... 
Iteration: 577300264, states[0] = -94.240747, states[40]= 0.000001
Saving checkpoint... 
Iteration: 587316736, states[0] = -94.264487, states[40]= 0.000001
Saving checkpoint... 
Iteration: 595809061, states[0] = 16.338814, states[40]= 0.012854
Saving checkpoint... 
Iteration: 605341202, states[0] = -94.266729, states[40]= 0.000001
Saving checkpoint... 
Iteration: 614585709, states[0] = -94.259160, states[40]= 0.000001
Saving checkpoint... 
Iteration: 623101600, states[0] = -94.106667, states[40]= 0.000001
Saving checkpoint... 
Iteration: 633362682, states[0] = -14.626010, states[40]= 0.005477
Saving checkpoint... 
Iteration: 643077382, states[0] = -94.259167, states[40]= 0.000001
Saving checkpoint... 
Iteration: 651817606, states[0] = -94.263057, states[40]= 0.000001
Saving checkpoint... 
Iteration: 660267462, states[0] = 34.629195, states[40]= 0.008983
Saving checkpoint... 
Iteration: 668469119, states[0] = -94.265949, states[40]= 0.000001
Saving checkpoint... 
Iteration: 677438319, states[0] = -94.266921, states[40]= 0.000001
Saving checkpoint... 
Iteration: 685463808, states[0] = -94.224091, states[40]= 0.000001
Saving checkpoint... 
Iteration: 694007742, states[0] = -94.263136, states[40]= 0.000001
Saving checkpoint... 
Iteration: 703507993, states[0] = 27.832565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711911172, states[0] = -94.266577, states[40]= 0.000001
Saving checkpoint... 
Iteration: 720512921, states[0] = -93.781183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729995466, states[0] = -94.263045, states[40]= 0.000001
Saving checkpoint... 
Iteration: 740407446, states[0] = -94.265914, states[40]= 0.000001
Saving checkpoint... 
Iteration: 748384541, states[0] = -94.229206, states[40]= 0.000001
Saving checkpoint... 
Iteration: 756391964, states[0] = -28.314254, states[40]= 0.014578
Saving checkpoint... 
Iteration: 764292809, states[0] = -94.256302, states[40]= 0.000001
Saving checkpoint... 
Iteration: 773611903, states[0] = -94.253100, states[40]= 0.000001
Saving checkpoint... 
Iteration: 781327201, states[0] = -94.233435, states[40]= 0.000001
Saving checkpoint... 
Iteration: 790503328, states[0] = 19.453559, states[40]= 1.301708
Saving checkpoint... 
Iteration: 799865889, states[0] = -16.675154, states[40]= 0.006320
Saving checkpoint... 
Iteration: 809500224, states[0] = -94.260845, states[40]= 0.000001
Saving checkpoint... 
Iteration: 819563650, states[0] = -94.004908, states[40]= 0.000001
Saving checkpoint... 
Iteration: 829311512, states[0] = -94.233682, states[40]= 0.000001
Saving checkpoint... 
Iteration: 838925880, states[0] = -44.182802, states[40]= 0.002889
Saving checkpoint... 
Iteration: 848653817, states[0] = -94.247569, states[40]= 0.000001
Saving checkpoint... 
Iteration: 856776463, states[0] = 31.056880, states[40]= 0.009527
Saving checkpoint... 
Iteration: 866303142, states[0] = -94.255732, states[40]= 0.000001
Saving checkpoint... 
Iteration: 875188552, states[0] = -94.210304, states[40]= 0.000001
Saving checkpoint... 
Iteration: 883897092, states[0] = -30.175789, states[40]= 0.012823
Saving checkpoint... 
Iteration: 892974365, states[0] = -90.450364, states[40]= 0.000003
Saving checkpoint... 
Iteration: 902121518, states[0] = -94.135620, states[40]= 0.000001
Saving checkpoint... 
Iteration: 911666086, states[0] = -94.244960, states[40]= 0.000001
Saving checkpoint... 
Iteration: 921568413, states[0] = -94.017141, states[40]= 0.000001
Saving checkpoint... 
Iteration: 930509311, states[0] = -93.753626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940652048, states[0] = -5.824689, states[40]= 0.002576
Saving checkpoint... 
Iteration: 950206832, states[0] = -94.220507, states[40]= 0.000001
Saving checkpoint... 
Iteration: 959447135, states[0] = -94.259882, states[40]= 0.000001
Saving checkpoint... 
Iteration: 967770951, states[0] = 33.403450, states[40]= 0.008802
Saving checkpoint... 
Iteration: 977372328, states[0] = -94.259670, states[40]= 0.000001
Saving checkpoint... 
Iteration: 985500990, states[0] = 43.617563, states[40]= 1.542198
Saving checkpoint... 
Iteration: 993165509, states[0] = -13.057406, states[40]= 0.003024
Saving checkpoint... 
Iteration: 1001441857, states[0] = -94.259049, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1010231726, states[0] = -94.231768, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1019952877, states[0] = -94.216952, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1030507762, states[0] = 27.628887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039123291, states[0] = -94.245749, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1048817854, states[0] = 12.208104, states[40]= 0.012673
Saving checkpoint... 
Iteration: 1058416764, states[0] = -94.258225, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1066926756, states[0] = -44.653130, states[40]= 0.002725
Saving checkpoint... 
Iteration: 1076397279, states[0] = -94.257836, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1085219726, states[0] = -94.224292, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1094037225, states[0] = -93.897816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102578623, states[0] = 22.948549, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1111171590, states[0] = -94.239675, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1121529041, states[0] = -94.251431, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1131578416, states[0] = -94.040224, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1141182372, states[0] = -94.237971, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1150531095, states[0] = 33.963899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159821300, states[0] = 10.525420, states[40]= 0.012509
Saving checkpoint... 
Iteration: 1168875095, states[0] = -21.680166, states[40]= 0.012371
Saving checkpoint... 
Iteration: 1178885011, states[0] = -94.218829, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1188590360, states[0] = -94.068525, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1198022645, states[0] = -94.250049, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1206890928, states[0] = -94.254627, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1215664440, states[0] = -94.181703, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1226261791, states[0] = -94.237560, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1234970708, states[0] = -85.545048, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1243630916, states[0] = 3.451145, states[40]= 0.000955
Saving checkpoint... 
Iteration: 1250979933, states[0] = -94.209197, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1259442460, states[0] = -94.252829, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1266917196, states[0] = -94.253206, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1274485516, states[0] = -94.250556, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1283609224, states[0] = -94.241104, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1293963928, states[0] = -94.251176, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1304079079, states[0] = -94.037729, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1314985713, states[0] = -94.249568, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1325902173, states[0] = -94.213825, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1335639085, states[0] = -94.150302, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1344501944, states[0] = -93.694214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353582446, states[0] = -94.045279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1362304367, states[0] = 18.581654, states[40]= 0.012782
Saving checkpoint... 
Iteration: 1372709286, states[0] = -25.473059, states[40]= 0.017730
Saving checkpoint... 
Iteration: 1383186150, states[0] = -21.662352, states[40]= 0.012647
Saving checkpoint... 
Iteration: 1392857479, states[0] = -94.248975, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1402021309, states[0] = -94.245242, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1412155516, states[0] = -94.167857, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1421839540, states[0] = -94.216957, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1430713787, states[0] = -94.228132, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1439771473, states[0] = -94.222636, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1449152764, states[0] = -6.175631, states[40]= 0.002605
Saving checkpoint... 
Iteration: 1458319172, states[0] = 11.574785, states[40]= 0.012613
Saving checkpoint... 
Iteration: 1466558550, states[0] = -94.240915, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1476790999, states[0] = -94.238805, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1487173167, states[0] = -94.183171, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1495934415, states[0] = -49.435714, states[40]= 0.001469
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.077567
 - CaMKt in component CaMK (millimolar): 0.011996
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 8.054530
 - nass in component intracellular_ions (millimolar): 8.054697
 - ki in component intracellular_ions (millimolar): 143.576737
 - kss in component intracellular_ions (millimolar): 143.576719
 - cansr in component intracellular_ions (millimolar): 2.144691
 - cajsr in component intracellular_ions (millimolar): 2.147912
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.003932
 - hf in component INa (dimensionless): 0.864945
 - hs in component INa (dimensionless): 0.864949
 - j in component INa (dimensionless): 0.864967
 - hsp in component INa (dimensionless): 0.698116
 - jp in component INa (dimensionless): 0.864978
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707089
 - hLp in component INaL (dimensionless): 0.500255
 - a in component Ito (dimensionless): 0.000659
 - iF in component Ito (dimensionless): 0.999849
 - iS in component Ito (dimensionless): 0.938449
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999849
 - iSp in component Ito (dimensionless): 0.964028
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.966844
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005036
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.059573
 - xs1 in component IKs (dimensionless): 0.161057
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997545
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
15:24:53 (1600): called boinc_finish(0)

</stderr_txt>
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