𝕏

Task 55171785

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_5000-conf_519_0
Workunit 26199510
Created 28 Jun 2024, 5:46:27 UTC
Sent 28 Jun 2024, 21:47:03 UTC
Report deadline 1 Jul 2024, 21:47:03 UTC
Received 1 Jul 2024, 13:04:31 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214250
Run time 3 hours 8 min 38 sec
CPU time 2 hours 20 min 56 sec
Validate state Valid
Credit 44.49
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.18 MB
Peak swap size 6.26 MB
Peak disk usage 1.55 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_5000-conf_519.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_5000-conf_519_0_r540812350_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_5000-conf_519_0_r540812350_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 113.811177
     * GNaL_b in INaL: 0.006263
     * Gto_b in Ito: 0.072596
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032781
     * GKs_b in IKs: 0.001800
     * GK1_b in IK1: 0.153128
     * Gncx_b in INaCa_i: 0.000958
     * Pnak_b in INaK: 73.681314
     * GKb_b in IKb: 0.003735
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.027739
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1497500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8146179, states[0] = -94.516628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17363455, states[0] = -94.420949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25884494, states[0] = -94.387706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35101495, states[0] = -3.569588, states[40]= 0.003975
Saving checkpoint... 
Iteration: 43945921, states[0] = -94.319101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53893055, states[0] = -94.302801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62744311, states[0] = -93.920751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71471449, states[0] = -94.282934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79739969, states[0] = -94.268754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89047323, states[0] = -94.271297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98233645, states[0] = -94.281781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106266371, states[0] = -94.270452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115119741, states[0] = -15.619789, states[40]= 0.001674
Saving checkpoint... 
Iteration: 125637638, states[0] = -94.270400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133594559, states[0] = -94.269126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142967868, states[0] = -94.229739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152128239, states[0] = -94.251237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160792774, states[0] = -94.272021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169088479, states[0] = -94.256024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176716371, states[0] = -94.253869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185196472, states[0] = -86.879013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193935974, states[0] = -94.257539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203366872, states[0] = -94.269730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212026702, states[0] = -94.249489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221432125, states[0] = -94.257023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228438575, states[0] = -94.268012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237615767, states[0] = -11.933881, states[40]= 0.002215
Saving checkpoint... 
Iteration: 246186498, states[0] = -94.261903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255495871, states[0] = -94.236970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264650053, states[0] = -94.247904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273322318, states[0] = -94.269413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282512022, states[0] = 28.058075, states[40]= 0.025322
Saving checkpoint... 
Iteration: 291550299, states[0] = -94.254500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299883642, states[0] = -94.246173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308162889, states[0] = -94.265897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317497947, states[0] = -94.245482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326653165, states[0] = -94.252898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335943369, states[0] = -94.267401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344743308, states[0] = -94.247002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353093056, states[0] = -94.258993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360967346, states[0] = -94.266843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370599572, states[0] = -94.259848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379317728, states[0] = -94.250769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388373814, states[0] = -94.268632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397629252, states[0] = -23.053145, states[40]= 0.001559
Saving checkpoint... 
Iteration: 406255609, states[0] = -94.259917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415772628, states[0] = -94.269188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426361645, states[0] = -94.257670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434798132, states[0] = -94.246550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443820956, states[0] = -94.258484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453297231, states[0] = -94.269235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462219590, states[0] = -94.247071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470814631, states[0] = -94.269178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478965743, states[0] = -94.255690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487787326, states[0] = -94.012767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495850037, states[0] = -94.268870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505070519, states[0] = 13.805210, states[40]= 0.004465
Saving checkpoint... 
Iteration: 514088642, states[0] = -94.253670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523685353, states[0] = -94.261450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531790557, states[0] = -94.250974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539278158, states[0] = -94.251116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548167915, states[0] = -94.265993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557041142, states[0] = -94.248420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565697394, states[0] = -94.267452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576422739, states[0] = -94.256401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585371326, states[0] = -94.155338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594603984, states[0] = -94.247867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603466743, states[0] = -94.266685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611234231, states[0] = -94.260261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619368948, states[0] = -94.250042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628046275, states[0] = -94.250563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637520739, states[0] = 27.722312, states[40]= 0.003310
Saving checkpoint... 
Iteration: 646811248, states[0] = -94.250661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654405848, states[0] = -94.249635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662724875, states[0] = -93.804918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671304613, states[0] = -94.258679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681957007, states[0] = -94.249111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690625795, states[0] = -94.262607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699023797, states[0] = -94.254567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708033198, states[0] = -94.247469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717190072, states[0] = -94.247121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726397842, states[0] = -94.256771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735894245, states[0] = -94.268072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744363779, states[0] = -94.250017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754274379, states[0] = -94.251023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762147580, states[0] = -94.247414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772001624, states[0] = -94.248635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781769231, states[0] = -94.251067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789392000, states[0] = -94.249691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798740339, states[0] = -94.260003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807448838, states[0] = -94.245388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815818721, states[0] = -94.268936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823473071, states[0] = -94.266401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831826548, states[0] = -94.250369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839529245, states[0] = -94.248344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849610422, states[0] = -94.247651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858339057, states[0] = -94.268754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867499615, states[0] = -94.245070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876341818, states[0] = -94.257777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886327574, states[0] = -94.258062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893554764, states[0] = -94.264397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901711867, states[0] = -94.251704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910965524, states[0] = -94.266516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920506205, states[0] = -94.239749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928565417, states[0] = -94.264112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938829722, states[0] = -94.257984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947900709, states[0] = -94.183342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956575696, states[0] = -94.253583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966089283, states[0] = -94.263498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975738567, states[0] = -94.268393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984132762, states[0] = -94.252723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991897693, states[0] = -94.249502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999420041, states[0] = -94.249270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008475170, states[0] = -94.266234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019194901, states[0] = -94.251850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028412098, states[0] = -94.267560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036922971, states[0] = -94.249217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045801111, states[0] = -94.268851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054407435, states[0] = -94.249362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062369100, states[0] = -94.245694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069839020, states[0] = -94.245876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077774323, states[0] = -93.977906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087318169, states[0] = -94.245998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096440511, states[0] = -94.255743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105586794, states[0] = -94.257596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113252014, states[0] = -94.268528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123189832, states[0] = -94.266773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130067656, states[0] = 14.913621, states[40]= 0.004326
Saving checkpoint... 
Iteration: 1138096684, states[0] = -94.258965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144797278, states[0] = -94.246098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154111960, states[0] = -94.252914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161505479, states[0] = -94.254573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171882385, states[0] = -94.249546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180093439, states[0] = 3.297288, states[40]= 0.004880
Saving checkpoint... 
Iteration: 1189738868, states[0] = -94.246466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199456386, states[0] = -94.248785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207922950, states[0] = -94.199956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216637698, states[0] = -94.252504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226883262, states[0] = -94.249501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236610733, states[0] = -94.252879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244865664, states[0] = -94.245598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254563350, states[0] = -94.247782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264500887, states[0] = -94.248326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272816805, states[0] = -94.076028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283416297, states[0] = -94.267317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291674867, states[0] = -94.251943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300488946, states[0] = -94.233569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308557983, states[0] = -94.264052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316259106, states[0] = -94.259252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325494263, states[0] = -94.235483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335061878, states[0] = 17.030165, states[40]= 0.004009
Saving checkpoint... 
Iteration: 1344654677, states[0] = -94.246986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352843337, states[0] = -94.119542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362443503, states[0] = -94.245063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372817889, states[0] = -94.077974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381434052, states[0] = -94.255678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391925028, states[0] = -94.248969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400497618, states[0] = -94.236605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409760985, states[0] = -94.246172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417646400, states[0] = -36.864706, states[40]= 0.000671
Saving checkpoint... 
Iteration: 1425361060, states[0] = -94.142934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433429125, states[0] = -94.266965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441594193, states[0] = -94.252993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447610580, states[0] = -7.751947, states[40]= 0.003125
Saving checkpoint... 
Iteration: 1457125493, states[0] = -94.247141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467214524, states[0] = -94.246462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477301364, states[0] = -94.245858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488004073, states[0] = -94.238702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498822580, states[0] = -94.257773, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.120637
 - CaMKt in component CaMK (millimolar): 0.001126
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.292484
 - nass in component intracellular_ions (millimolar): 6.292570
 - ki in component intracellular_ions (millimolar): 145.632532
 - kss in component intracellular_ions (millimolar): 145.632522
 - cansr in component intracellular_ions (millimolar): 1.570332
 - cajsr in component intracellular_ions (millimolar): 1.570320
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003915
 - hf in component INa (dimensionless): 0.865769
 - hs in component INa (dimensionless): 0.865770
 - j in component INa (dimensionless): 0.865771
 - hsp in component INa (dimensionless): 0.699587
 - jp in component INa (dimensionless): 0.865772
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.708089
 - hLp in component INaL (dimensionless): 0.514467
 - a in component Ito (dimensionless): 0.000657
 - iF in component Ito (dimensionless): 0.999851
 - iS in component Ito (dimensionless): 0.997720
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999851
 - iSp in component Ito (dimensionless): 0.999234
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998884
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003033
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001899
 - xs1 in component IKs (dimensionless): 0.022339
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997535
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:04:12 (5332): called boinc_finish(0)

</stderr_txt>
]]>


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