𝕏

Task 55171781

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_5000-conf_319_0
Workunit 26199508
Created 28 Jun 2024, 5:46:27 UTC
Sent 28 Jun 2024, 21:47:03 UTC
Report deadline 1 Jul 2024, 21:47:03 UTC
Received 1 Jul 2024, 9:55:16 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214250
Run time 3 hours 10 min 13 sec
CPU time 2 hours 20 min 51 sec
Validate state Valid
Credit 44.90
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.16 MB
Peak swap size 6.23 MB
Peak disk usage 1.55 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_5000-conf_319.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_5000-conf_319_0_r1090743037_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_5000-conf_319_0_r1090743037_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 96.057462
     * GNaL_b in INaL: 0.006700
     * Gto_b in Ito: 0.093167
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032954
     * GKs_b in IKs: 0.001958
     * GK1_b in IK1: 0.149530
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 75.277227
     * GKb_b in IKb: 0.003903
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.053985
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1497500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9431864, states[0] = -94.588218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 18022735, states[0] = -94.498304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26495656, states[0] = -94.459778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35336005, states[0] = -94.285807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45108348, states[0] = -5.445589, states[40]= 0.003286
Saving checkpoint... 
Iteration: 54221674, states[0] = -94.375822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63688839, states[0] = -94.371041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71968401, states[0] = -94.351615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81189168, states[0] = -94.355157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90334977, states[0] = -94.200205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99518935, states[0] = -94.333916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108001406, states[0] = -94.319113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117229784, states[0] = -94.326576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126594337, states[0] = -94.330291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135633471, states[0] = -94.336836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145680919, states[0] = -94.338648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154278635, states[0] = -94.324057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163419696, states[0] = -94.338213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170923684, states[0] = -94.337602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179319208, states[0] = -94.321770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188883688, states[0] = -94.327177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198731104, states[0] = -94.329723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208818849, states[0] = -94.327692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217094331, states[0] = -94.318098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225999153, states[0] = -94.334136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235554934, states[0] = -94.320421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243981987, states[0] = -94.324280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252702883, states[0] = -90.089495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261503464, states[0] = -94.323793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271256506, states[0] = -94.328076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279642401, states[0] = -94.317073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288251273, states[0] = -94.336017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296340089, states[0] = -94.326348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303575839, states[0] = -94.331839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311820934, states[0] = -94.319634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319621420, states[0] = -94.317084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329173448, states[0] = -94.321226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337821700, states[0] = -94.158186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346576093, states[0] = -94.322455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354381473, states[0] = -94.318970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364326904, states[0] = -94.319485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372488135, states[0] = -94.314891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381271773, states[0] = -94.327504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389762308, states[0] = -94.316074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399018106, states[0] = -94.323226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407211815, states[0] = -94.316370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414592245, states[0] = -94.317174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422131678, states[0] = -94.316889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431222979, states[0] = -94.328455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439982057, states[0] = -94.314863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449122541, states[0] = -94.321740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456529997, states[0] = -94.323007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465498280, states[0] = -94.305277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473757028, states[0] = -94.327727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482077753, states[0] = -94.317232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491146077, states[0] = -94.330062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500746825, states[0] = -94.335675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509485787, states[0] = -94.317930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517412621, states[0] = -94.315151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526668780, states[0] = -94.321107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536049127, states[0] = -94.332193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544219522, states[0] = -94.320496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551375764, states[0] = -94.325427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561234494, states[0] = -94.328129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570394877, states[0] = -94.248498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579909051, states[0] = -94.315128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589998727, states[0] = -94.314684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600906912, states[0] = -94.335029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609030419, states[0] = -94.322900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618504109, states[0] = -94.333128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628004460, states[0] = -94.307145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636437695, states[0] = -94.324317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644600150, states[0] = -94.316963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652081445, states[0] = -94.317094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661320901, states[0] = -94.326358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670720880, states[0] = -94.334994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680690082, states[0] = -94.333890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690091224, states[0] = 6.124428, states[40]= 0.004346
Saving checkpoint... 
Iteration: 698259988, states[0] = -94.335735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706883040, states[0] = -94.318702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716359040, states[0] = -94.325619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724136620, states[0] = -94.321379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733568641, states[0] = -94.331630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742726023, states[0] = -93.885099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751850360, states[0] = -94.318983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760810108, states[0] = -94.335918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770476836, states[0] = -94.297291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778037520, states[0] = -94.315894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786903576, states[0] = -94.318461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796481397, states[0] = -94.323517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805642610, states[0] = -94.330929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813420095, states[0] = -94.334669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822012246, states[0] = -94.317513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830408271, states[0] = -94.259062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839701506, states[0] = -94.316149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848740218, states[0] = -94.327825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856946541, states[0] = -94.318035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866264953, states[0] = -94.327313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875570834, states[0] = -94.322365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882927039, states[0] = -94.271979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890614913, states[0] = -94.328307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898614371, states[0] = -94.330500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907494429, states[0] = -94.314499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915659894, states[0] = -94.332103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924421453, states[0] = -94.318211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933930419, states[0] = -94.324245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942137646, states[0] = -94.316507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950891436, states[0] = -94.335045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960059813, states[0] = 18.284050, states[40]= 0.003087
Saving checkpoint... 
Iteration: 968817144, states[0] = -94.326231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978139093, states[0] = -94.330533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985563218, states[0] = -94.320978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993727879, states[0] = -94.327986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003200343, states[0] = -94.334105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011570814, states[0] = -94.322066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019151935, states[0] = -94.320996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026988930, states[0] = -94.317569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035675500, states[0] = -94.332949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044306633, states[0] = -94.319230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052293644, states[0] = -94.315450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061456416, states[0] = -94.323739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069943210, states[0] = -94.314640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078884475, states[0] = -94.324933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087598932, states[0] = 2.243780, states[40]= 0.004308
Saving checkpoint... 
Iteration: 1096202440, states[0] = -94.328453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105150828, states[0] = -37.358892, states[40]= 0.000540
Saving checkpoint... 
Iteration: 1114151450, states[0] = -94.320940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124176916, states[0] = -94.320621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134711020, states[0] = -94.315897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142459310, states[0] = -94.314514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151392054, states[0] = -94.324754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160566502, states[0] = -94.321444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168945045, states[0] = -94.323853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177852354, states[0] = -94.203405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187413671, states[0] = -94.314712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196669467, states[0] = -94.320665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207122402, states[0] = -94.316441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215568112, states[0] = -94.321686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224831537, states[0] = -94.315124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233986287, states[0] = -94.323158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243012757, states[0] = -94.309228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252959752, states[0] = -94.289583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261015013, states[0] = -94.332477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268966648, states[0] = -94.323442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278073599, states[0] = -94.322560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286887275, states[0] = -94.318287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294804599, states[0] = -94.315230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303663747, states[0] = -94.329150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312154987, states[0] = -94.316149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322207106, states[0] = -94.315801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331465485, states[0] = -94.323420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340301439, states[0] = -94.118623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348416475, states[0] = -94.334387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356418260, states[0] = -94.324174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365991028, states[0] = -94.332925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374282136, states[0] = -94.319271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383870980, states[0] = -94.324974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392215514, states[0] = -94.315702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400495383, states[0] = -94.303706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410340889, states[0] = -94.187715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419304849, states[0] = -94.319005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427719166, states[0] = -93.806939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436468326, states[0] = -94.323307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445148565, states[0] = -35.468688, states[40]= 0.000680
Saving checkpoint... 
Iteration: 1453959842, states[0] = -94.323431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463171634, states[0] = -94.332460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471695782, states[0] = -94.320172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481494804, states[0] = -94.322868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490747296, states[0] = -94.335043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499987612, states[0] = -94.314148, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.190065
 - CaMKt in component CaMK (millimolar): 0.001051
 - cass in component intracellular_ions (millimolar): 0.000084
 - nai in component intracellular_ions (millimolar): 6.191009
 - nass in component intracellular_ions (millimolar): 6.191090
 - ki in component intracellular_ions (millimolar): 145.745805
 - kss in component intracellular_ions (millimolar): 145.745794
 - cansr in component intracellular_ions (millimolar): 1.512812
 - cajsr in component intracellular_ions (millimolar): 1.512920
 - cai in component intracellular_ions (millimolar): 0.000086
 - m in component INa (dimensionless): 0.003888
 - hf in component INa (dimensionless): 0.867090
 - hs in component INa (dimensionless): 0.867090
 - j in component INa (dimensionless): 0.867091
 - hsp in component INa (dimensionless): 0.701979
 - jp in component INa (dimensionless): 0.867091
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.709999
 - hLp in component INaL (dimensionless): 0.516771
 - a in component Ito (dimensionless): 0.000654
 - iF in component Ito (dimensionless): 0.999852
 - iS in component Ito (dimensionless): 0.997718
 - ap in component Ito (dimensionless): 0.000333
 - iFp in component Ito (dimensionless): 0.999852
 - iSp in component Ito (dimensionless): 0.999236
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998859
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002612
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001830
 - xs1 in component IKs (dimensionless): 0.022999
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997518
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:54:48 (9972): called boinc_finish(0)

</stderr_txt>
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