𝕏

Task 55171769

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_2000-conf_719_0
Workunit 26199502
Created 28 Jun 2024, 5:46:27 UTC
Sent 28 Jun 2024, 21:47:03 UTC
Report deadline 1 Jul 2024, 21:47:03 UTC
Received 1 Jul 2024, 11:56:20 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214250
Run time 3 hours 8 min 25 sec
CPU time 2 hours 20 min 21 sec
Validate state Valid
Credit 44.71
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.15 MB
Peak swap size 6.22 MB
Peak disk usage 0.64 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_2000-conf_719.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_2000-conf_719_0_r412515453_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_2000-conf_719_0_r412515453_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 97.644693
     * GNaL_b in INaL: 0.005574
     * Gto_b in Ito: 0.074426
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.029656
     * GKs_b in IKs: 0.002099
     * GK1_b in IK1: 0.174183
     * Gncx_b in INaCa_i: 0.000973
     * Pnak_b in INaK: 68.644907
     * GKb_b in IKb: 0.003681
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029195
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8779412, states[0] = -94.886430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16694212, states[0] = -94.837998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25854792, states[0] = -94.808182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33862431, states[0] = -94.792253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42304928, states[0] = -94.609106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51351848, states[0] = -94.664610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60761487, states[0] = -94.769381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69290029, states[0] = -94.563302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78699954, states[0] = -94.761967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88629502, states[0] = -94.756206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98041221, states[0] = 22.990281, states[40]= 0.002102
Saving checkpoint... 
Iteration: 107105112, states[0] = -5.014829, states[40]= 0.003677
Saving checkpoint... 
Iteration: 115475570, states[0] = -94.724877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123514844, states[0] = -94.735339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131063652, states[0] = 15.698769, states[40]= 0.003583
Saving checkpoint... 
Iteration: 139669638, states[0] = -94.752904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148923028, states[0] = -94.752716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157931729, states[0] = -94.752191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167261955, states[0] = -94.485920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176294018, states[0] = -94.558591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185558337, states[0] = -94.741226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195008920, states[0] = 28.195330, states[40]= 0.067873
Saving checkpoint... 
Iteration: 203916377, states[0] = -94.751566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212865500, states[0] = -94.752395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222163356, states[0] = -52.942364, states[40]= 0.000068
Saving checkpoint... 
Iteration: 230385807, states[0] = -94.673679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239783190, states[0] = -94.752956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249357732, states[0] = -94.648429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257641265, states[0] = -94.749270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265181347, states[0] = -71.978802, states[40]= 0.000003
Saving checkpoint... 
Iteration: 274688120, states[0] = -94.751458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283637281, states[0] = -94.748914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292076147, states[0] = 10.813621, states[40]= 0.004317
Saving checkpoint... 
Iteration: 300464433, states[0] = -94.716878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308019650, states[0] = 27.856833, states[40]= 0.003099
Saving checkpoint... 
Iteration: 316390650, states[0] = -94.677047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325296241, states[0] = -94.561783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334255549, states[0] = -94.467080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343063946, states[0] = 15.640598, states[40]= 0.003611
Saving checkpoint... 
Iteration: 351858880, states[0] = -94.751947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360051035, states[0] = 20.059793, states[40]= 0.002722
Saving checkpoint... 
Iteration: 369161995, states[0] = -51.675277, states[40]= 0.000083
Saving checkpoint... 
Iteration: 378130472, states[0] = -25.227220, states[40]= 0.001561
Saving checkpoint... 
Iteration: 386802216, states[0] = -94.752472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394599934, states[0] = -94.745534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404793793, states[0] = -94.752476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414130795, states[0] = -25.484012, states[40]= 0.001559
Saving checkpoint... 
Iteration: 423606105, states[0] = -94.746088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433452494, states[0] = -94.711854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442410158, states[0] = -94.690088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452050638, states[0] = 20.187168, states[40]= 0.002696
Saving checkpoint... 
Iteration: 461782839, states[0] = -94.752394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470408920, states[0] = -94.689261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479205085, states[0] = -94.164546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487727859, states[0] = -94.751973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497755091, states[0] = -94.752256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507722270, states[0] = -94.751841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517279071, states[0] = -94.526096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526361919, states[0] = -94.651986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536008527, states[0] = 28.261526, states[40]= 0.077332
Saving checkpoint... 
Iteration: 545339660, states[0] = -94.627568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553545234, states[0] = -94.737764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561689173, states[0] = -94.750898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570442926, states[0] = -94.707398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578583038, states[0] = -94.743302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586461626, states[0] = -94.715244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596996304, states[0] = -94.748658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606239670, states[0] = -94.418350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615223705, states[0] = -94.363230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624203581, states[0] = -94.079063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633029240, states[0] = 26.235986, states[40]= 0.001684
Saving checkpoint... 
Iteration: 643439505, states[0] = -94.705668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652094696, states[0] = 1.786316, states[40]= 0.004613
Saving checkpoint... 
Iteration: 659513057, states[0] = -94.730911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669653455, states[0] = -94.749134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677593157, states[0] = -94.744286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687729306, states[0] = -94.751622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697790096, states[0] = -94.751939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705218578, states[0] = -94.343046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715009952, states[0] = 28.116001, states[40]= 0.048202
Saving checkpoint... 
Iteration: 724681835, states[0] = -94.750335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733849648, states[0] = -94.751357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742014724, states[0] = 28.134120, states[40]= 0.010552
Saving checkpoint... 
Iteration: 751019938, states[0] = 27.827429, states[40]= 0.002944
Saving checkpoint... 
Iteration: 759985112, states[0] = -94.748622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769963422, states[0] = -94.749110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778060433, states[0] = 16.904199, states[40]= 0.003372
Saving checkpoint... 
Iteration: 787715811, states[0] = -94.751192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795455670, states[0] = -94.712490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803667027, states[0] = -94.749570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812451834, states[0] = -94.710866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821294684, states[0] = -94.557878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830830900, states[0] = -94.751405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840518671, states[0] = -94.731884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849860138, states[0] = -94.750991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858255737, states[0] = -94.466606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866609337, states[0] = -94.745563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875453927, states[0] = -94.711624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884679617, states[0] = -94.749952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894781045, states[0] = -94.751588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904588366, states[0] = -94.743324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914401632, states[0] = -94.683690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923253475, states[0] = -94.460038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931972296, states[0] = -94.748603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939275946, states[0] = -94.518186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948486006, states[0] = -94.722995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957730891, states[0] = -94.751142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965545722, states[0] = -94.737081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974380700, states[0] = -94.668010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983480306, states[0] = -94.721125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992586343, states[0] = -94.742925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002110737, states[0] = -9.057500, states[40]= 0.002781
Saving checkpoint... 
Iteration: 1009474875, states[0] = -94.719267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018163922, states[0] = -53.440752, states[40]= 0.000062
Saving checkpoint... 
Iteration: 1027380893, states[0] = -94.668069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036921305, states[0] = -94.749535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046122829, states[0] = -19.062387, states[40]= 0.001468
Saving checkpoint... 
Iteration: 1054348988, states[0] = -94.637478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062352572, states[0] = -94.641381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071746783, states[0] = -94.751119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080557784, states[0] = -94.738869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089799719, states[0] = -94.751170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099620254, states[0] = -94.746078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108431935, states[0] = -94.701088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116325164, states[0] = -94.607498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125908196, states[0] = -94.749634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134753335, states[0] = -94.751055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143098799, states[0] = -0.623340, states[40]= 0.004407
Saving checkpoint... 
Iteration: 1151863949, states[0] = -94.750370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160168629, states[0] = -57.864761, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1168604414, states[0] = -94.744533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178004260, states[0] = 32.982623, states[40]= 0.311716
Saving checkpoint... 
Iteration: 1185611865, states[0] = -94.745198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196249098, states[0] = -94.446663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205589101, states[0] = -94.742847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214381174, states[0] = -94.667949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223549558, states[0] = -94.737262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232108383, states[0] = -7.218195, states[40]= 0.003197
Saving checkpoint... 
Iteration: 1241154119, states[0] = -44.640889, states[40]= 0.000238
Saving checkpoint... 
Iteration: 1248712853, states[0] = -94.750269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258026132, states[0] = 26.884745, states[40]= 0.001715
Saving checkpoint... 
Iteration: 1266972756, states[0] = -94.747967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276724384, states[0] = -94.750443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285131364, states[0] = -25.934979, states[40]= 0.001553
Saving checkpoint... 
Iteration: 1293568151, states[0] = -94.740014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303619575, states[0] = -94.745641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313211510, states[0] = -94.300640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320478204, states[0] = -94.719806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329307119, states[0] = -94.579268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337949546, states[0] = -94.748365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345844236, states[0] = -94.750286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353563181, states[0] = -94.739182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361563519, states[0] = -94.739217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369080084, states[0] = 9.093507, states[40]= 0.004482
Saving checkpoint... 
Iteration: 1378943708, states[0] = -94.748418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388455090, states[0] = -94.711145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397808757, states[0] = -94.750542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406101024, states[0] = -2.024176, states[40]= 0.004222
Saving checkpoint... 
Iteration: 1415683659, states[0] = -94.749113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424233158, states[0] = -94.395127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433348800, states[0] = -94.636558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442337423, states[0] = -94.623127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451558830, states[0] = -94.738339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460550161, states[0] = -94.736921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469555851, states[0] = -94.737837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478631727, states[0] = -94.746251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488236902, states[0] = -94.407595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497309603, states[0] = -94.583089, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.622821
 - CaMKt in component CaMK (millimolar): 0.004262
 - cass in component intracellular_ions (millimolar): 0.000085
 - nai in component intracellular_ions (millimolar): 6.496174
 - nass in component intracellular_ions (millimolar): 6.496262
 - ki in component intracellular_ions (millimolar): 145.414185
 - kss in component intracellular_ions (millimolar): 145.414171
 - cansr in component intracellular_ions (millimolar): 1.597776
 - cajsr in component intracellular_ions (millimolar): 1.596975
 - cai in component intracellular_ions (millimolar): 0.000088
 - m in component INa (dimensionless): 0.003722
 - hf in component INa (dimensionless): 0.875073
 - hs in component INa (dimensionless): 0.875074
 - j in component INa (dimensionless): 0.875079
 - hsp in component INa (dimensionless): 0.716644
 - jp in component INa (dimensionless): 0.875082
 - mL in component INaL (dimensionless): 0.000052
 - hL in component INaL (dimensionless): 0.721585
 - hLp in component INaL (dimensionless): 0.513406
 - a in component Ito (dimensionless): 0.000635
 - iF in component Ito (dimensionless): 0.999863
 - iS in component Ito (dimensionless): 0.890755
 - ap in component Ito (dimensionless): 0.000324
 - iFp in component Ito (dimensionless): 0.999863
 - iSp in component Ito (dimensionless): 0.930738
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.974346
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002766
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.099717
 - xs1 in component IKs (dimensionless): 0.128521
 - xs2 in component IKs (dimensionless): 0.000091
 - xk1 in component IK1 (dimensionless): 0.997409
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:56:06 (10192): called boinc_finish(0)

</stderr_txt>
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