𝕏

Task 55171763

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_2000-conf_419_0
Workunit 26199499
Created 28 Jun 2024, 5:46:27 UTC
Sent 28 Jun 2024, 21:47:03 UTC
Report deadline 1 Jul 2024, 21:47:03 UTC
Received 1 Jul 2024, 8:52:27 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214250
Run time 3 hours 11 min 6 sec
CPU time 2 hours 20 min 13 sec
Validate state Valid
Credit 44.17
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.16 MB
Peak swap size 6.23 MB
Peak disk usage 0.64 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_2000-conf_419.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_2000-conf_419_0_r1185964117_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_2000-conf_419_0_r1185964117_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 95.945177
     * GNaL_b in INaL: 0.004896
     * Gto_b in Ito: 0.074485
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.031485
     * GKs_b in IKs: 0.002090
     * GK1_b in IK1: 0.173354
     * Gncx_b in INaCa_i: 0.000958
     * Pnak_b in INaK: 74.674684
     * GKb_b in IKb: 0.003899
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.051758
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 7029409, states[0] = 23.623504, states[40]= 0.003554
Saving checkpoint... 
Iteration: 16748761, states[0] = -94.897675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25552588, states[0] = -94.849460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34149333, states[0] = -53.343810, states[40]= 0.000046
Saving checkpoint... 
Iteration: 45050062, states[0] = 18.486485, states[40]= 0.002938
Saving checkpoint... 
Iteration: 54776758, states[0] = -94.810889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62727338, states[0] = -94.804535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70332396, states[0] = -94.682023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78805545, states[0] = -94.796362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86972725, states[0] = -94.790749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95084845, states[0] = 4.300969, states[40]= 0.004594
Saving checkpoint... 
Iteration: 104003443, states[0] = 35.705107, states[40]= 0.374360
Saving checkpoint... 
Iteration: 111972867, states[0] = -94.785033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119906973, states[0] = -94.785238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129822519, states[0] = -94.785357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138651532, states[0] = -94.782357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145603425, states[0] = -94.778686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155448183, states[0] = -94.746545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164856915, states[0] = -94.782712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173334195, states[0] = -94.666773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182707706, states[0] = -94.782214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191368221, states[0] = -94.699394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200421864, states[0] = -94.733693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210325624, states[0] = -94.655786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219235167, states[0] = -94.471230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228770922, states[0] = -94.782127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237382981, states[0] = -94.710124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246238991, states[0] = -94.482590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254429926, states[0] = -94.737031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262242617, states[0] = -94.493121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270059120, states[0] = 15.868487, states[40]= 0.003600
Saving checkpoint... 
Iteration: 278084388, states[0] = 4.789919, states[40]= 0.004614
Saving checkpoint... 
Iteration: 286604803, states[0] = -94.776296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295775922, states[0] = -94.781805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306747976, states[0] = -94.781700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316958353, states[0] = -94.779235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325210454, states[0] = -94.386744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333491590, states[0] = -94.758309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341564420, states[0] = -94.771907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350503625, states[0] = -94.761220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359077176, states[0] = 8.370586, states[40]= 0.004494
Saving checkpoint... 
Iteration: 367611986, states[0] = -94.776698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376085927, states[0] = 3.969764, states[40]= 0.004610
Saving checkpoint... 
Iteration: 386250219, states[0] = -94.513926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394290935, states[0] = -94.603333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403450712, states[0] = -94.745322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413736577, states[0] = -94.781400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421922523, states[0] = -94.779771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431333426, states[0] = -94.664356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440573580, states[0] = -94.772858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449315877, states[0] = -94.642225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457391859, states[0] = -94.715623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465577917, states[0] = -94.773314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474265603, states[0] = -94.551973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483816999, states[0] = -94.781249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493592323, states[0] = -94.774770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501393560, states[0] = -94.716654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511243034, states[0] = -94.493796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520181882, states[0] = -89.545499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527612181, states[0] = -94.776443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536961998, states[0] = -94.778769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544728546, states[0] = -94.781092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554267818, states[0] = -94.556867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563710486, states[0] = -94.780776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571942367, states[0] = -94.779123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580837095, states[0] = -94.780884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588752449, states[0] = -94.781228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596869207, states[0] = -94.780420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605866545, states[0] = -94.780446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614613349, states[0] = -94.776389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622899353, states[0] = -94.779872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632365970, states[0] = -94.696114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640585605, states[0] = -94.773854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648068355, states[0] = 12.255911, states[40]= 0.004135
Saving checkpoint... 
Iteration: 657113294, states[0] = -16.540163, states[40]= 0.001480
Saving checkpoint... 
Iteration: 666530784, states[0] = -94.766225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676561607, states[0] = -94.770973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684484474, states[0] = -94.755809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692371977, states[0] = -94.700906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701513077, states[0] = -94.762719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711416439, states[0] = -94.729563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720433481, states[0] = -94.737735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728440424, states[0] = -94.740702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737648677, states[0] = -94.778415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746753308, states[0] = -94.780971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755542817, states[0] = -94.768109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764957310, states[0] = -94.778491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773905088, states[0] = -94.779518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782538704, states[0] = -94.767396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792492172, states[0] = -94.757683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801586004, states[0] = -94.773628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810425952, states[0] = -94.734128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818959926, states[0] = -94.778346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827381516, states[0] = -94.707894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835694132, states[0] = -94.779958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845300600, states[0] = -94.618870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854490013, states[0] = -94.757020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863011675, states[0] = 27.577293, states[40]= 0.027185
Saving checkpoint... 
Iteration: 872177413, states[0] = -82.985592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881153500, states[0] = -53.200323, states[40]= 0.000051
Saving checkpoint... 
Iteration: 889580298, states[0] = -94.772875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897903133, states[0] = -94.779348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905765651, states[0] = -94.780748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914740328, states[0] = -94.780604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924854972, states[0] = -94.780085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933641774, states[0] = -94.777726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942425152, states[0] = -94.733527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951819662, states[0] = -94.780450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960519663, states[0] = -94.763641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969208167, states[0] = -94.376625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976990388, states[0] = -94.777420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986259707, states[0] = -94.537166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994861544, states[0] = -94.779876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005236775, states[0] = -94.474494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013584026, states[0] = -94.773071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021673950, states[0] = -94.779029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029439023, states[0] = -94.739617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037374438, states[0] = -94.702257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046262644, states[0] = -94.544118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055029384, states[0] = 25.274009, states[40]= 0.002039
Saving checkpoint... 
Iteration: 1062910977, states[0] = -94.778929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070913174, states[0] = -94.778875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078085124, states[0] = 4.402248, states[40]= 0.004614
Saving checkpoint... 
Iteration: 1086159808, states[0] = -59.520844, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1094094463, states[0] = -1.100100, states[40]= 0.004267
Saving checkpoint... 
Iteration: 1103342146, states[0] = -94.672863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112794763, states[0] = -94.780358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121135967, states[0] = -36.730236, states[40]= 0.000533
Saving checkpoint... 
Iteration: 1129518386, states[0] = -94.763105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138069345, states[0] = 11.843335, states[40]= 0.004184
Saving checkpoint... 
Iteration: 1146390555, states[0] = -94.713619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154930497, states[0] = -94.778398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164255793, states[0] = -94.527139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172867928, states[0] = -94.779486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183365443, states[0] = -94.694755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192044734, states[0] = 20.821041, states[40]= 0.002685
Saving checkpoint... 
Iteration: 1201020424, states[0] = 27.021455, states[40]= 0.003053
Saving checkpoint... 
Iteration: 1209682174, states[0] = -94.778995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218461522, states[0] = -94.747855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227325775, states[0] = -94.653868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235288328, states[0] = -94.597247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243528311, states[0] = -94.764822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252834351, states[0] = -94.779802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261668565, states[0] = -94.778431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272789105, states[0] = -94.780116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282026065, states[0] = 26.030867, states[40]= 0.002069
Saving checkpoint... 
Iteration: 1290032092, states[0] = 24.584371, states[40]= 0.002097
Saving checkpoint... 
Iteration: 1298882858, states[0] = -94.779039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309430551, states[0] = -94.735441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317416844, states[0] = -94.728767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325520306, states[0] = -94.763163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334234017, states[0] = -94.465469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342415380, states[0] = -94.727963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351466299, states[0] = -94.749232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359674371, states[0] = -94.778484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368710089, states[0] = -94.779435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377315533, states[0] = -94.640203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386443492, states[0] = -94.740868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395258282, states[0] = -94.532982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402943438, states[0] = -94.777724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411918584, states[0] = -94.778206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421075315, states[0] = 9.231970, states[40]= 0.004434
Saving checkpoint... 
Iteration: 1429380806, states[0] = -94.706379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437265836, states[0] = -94.550894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446040308, states[0] = 22.214316, states[40]= 0.002441
Saving checkpoint... 
Iteration: 1455127930, states[0] = -29.580305, states[40]= 0.001051
Saving checkpoint... 
Iteration: 1465881716, states[0] = -94.778781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474421499, states[0] = -94.730864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483837687, states[0] = -94.779381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492745877, states[0] = -94.779691, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.652277
 - CaMKt in component CaMK (millimolar): 0.004034
 - cass in component intracellular_ions (millimolar): 0.000083
 - nai in component intracellular_ions (millimolar): 6.332383
 - nass in component intracellular_ions (millimolar): 6.332466
 - ki in component intracellular_ions (millimolar): 145.587044
 - kss in component intracellular_ions (millimolar): 145.587029
 - cansr in component intracellular_ions (millimolar): 1.561323
 - cajsr in component intracellular_ions (millimolar): 1.560497
 - cai in component intracellular_ions (millimolar): 0.000086
 - m in component INa (dimensionless): 0.003711
 - hf in component INa (dimensionless): 0.875601
 - hs in component INa (dimensionless): 0.875602
 - j in component INa (dimensionless): 0.875607
 - hsp in component INa (dimensionless): 0.717625
 - jp in component INa (dimensionless): 0.875610
 - mL in component INaL (dimensionless): 0.000052
 - hL in component INaL (dimensionless): 0.722396
 - hLp in component INaL (dimensionless): 0.515710
 - a in component Ito (dimensionless): 0.000634
 - iF in component Ito (dimensionless): 0.999864
 - iS in component Ito (dimensionless): 0.893790
 - ap in component Ito (dimensionless): 0.000323
 - iFp in component Ito (dimensionless): 0.999864
 - iSp in component Ito (dimensionless): 0.933454
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.976342
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002560
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.095528
 - xs1 in component IKs (dimensionless): 0.121952
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997402
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:52:02 (8620): called boinc_finish(0)

</stderr_txt>
]]>


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