𝕏

Task 55169049

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_333-conf_116_1
Workunit 26198145
Created 28 Jun 2024, 5:45:14 UTC
Sent 28 Jun 2024, 21:22:06 UTC
Report deadline 1 Jul 2024, 21:22:06 UTC
Received 29 Jun 2024, 3:06:53 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 226666
Run time 2 hours 50 min 32 sec
CPU time 2 hours 46 min 29 sec
Validate state Valid
Credit 41.69
Device peak FLOPS 2.76 GFLOPS
Application version Human ventricular cell models optimization v0.02
aarch64-unknown-linux-gnu
Peak working set size 2.20 MB
Peak swap size 10.95 MB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_333-conf_116.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_333-conf_116_1_r1272689692_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_333-conf_116_1_r1272689692_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 111.334729
     * GNaL_b in INaL: 0.005102
     * Gto_b in Ito: 0.076287
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.031122
     * GKs_b in IKs: 0.002039
     * GK1_b in IK1: 0.160407
     * Gncx_b in INaCa_i: 0.000957
     * Pnak_b in INaK: 73.570648
     * GKb_b in IKb: 0.003772
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034145
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9453374, states[0] = -87.761872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 19019556, states[0] = 17.903996, states[40]= 0.011653
Saving checkpoint... 
Iteration: 28437017, states[0] = -84.697453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37869829, states[0] = 5.752597, states[40]= 0.007124
Saving checkpoint... 
Iteration: 47344044, states[0] = 21.019908, states[40]= 0.019492
Saving checkpoint... 
Iteration: 56857819, states[0] = 12.981341, states[40]= 0.008540
Saving checkpoint... 
Iteration: 66358151, states[0] = 12.157535, states[40]= 0.008326
Saving checkpoint... 
Iteration: 75941945, states[0] = -87.524426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85402311, states[0] = -41.204284, states[40]= 0.000129
Saving checkpoint... 
Iteration: 95123659, states[0] = -87.777394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104659675, states[0] = 33.969231, states[40]= 0.099210
Saving checkpoint... 
Iteration: 114422764, states[0] = -77.077293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123610846, states[0] = -87.715736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132961392, states[0] = -87.808533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142639440, states[0] = -87.848800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152243726, states[0] = -62.616177, states[40]= 0.000005
Saving checkpoint... 
Iteration: 161738612, states[0] = -56.304409, states[40]= 0.000013
Saving checkpoint... 
Iteration: 171162876, states[0] = 22.011555, states[40]= 0.026406
Saving checkpoint... 
Iteration: 180619931, states[0] = -87.796214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190175200, states[0] = 14.626703, states[40]= 0.009067
Saving checkpoint... 
Iteration: 199779021, states[0] = -87.773404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209349457, states[0] = 8.270454, states[40]= 0.007557
Saving checkpoint... 
Iteration: 215914475, states[0] = -80.033604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224185741, states[0] = 4.830064, states[40]= 0.006981
Saving checkpoint... 
Iteration: 233717934, states[0] = -37.170515, states[40]= 0.000221
Saving checkpoint... 
Iteration: 243322957, states[0] = 21.720835, states[40]= 0.023960
Saving checkpoint... 
Iteration: 252702357, states[0] = -17.754283, states[40]= 0.001554
Saving checkpoint... 
Iteration: 261598643, states[0] = -87.730564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270954876, states[0] = -87.832937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280074653, states[0] = -79.928855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289189317, states[0] = -5.013732, states[40]= 0.004742
Saving checkpoint... 
Iteration: 298464381, states[0] = -87.869122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307733104, states[0] = -70.749708, states[40]= 0.000001
Saving checkpoint... 
Iteration: 317094194, states[0] = -87.739036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326444397, states[0] = -87.816636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335526692, states[0] = -16.725346, states[40]= 0.001718
Saving checkpoint... 
Iteration: 344777729, states[0] = -87.822818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351826350, states[0] = 14.229676, states[40]= 0.008921
Saving checkpoint... 
Iteration: 358391210, states[0] = -64.901320, states[40]= 0.000003
Saving checkpoint... 
Iteration: 365171282, states[0] = 5.123554, states[40]= 0.007031
Saving checkpoint... 
Iteration: 371804700, states[0] = 24.667097, states[40]= 0.062080
Saving checkpoint... 
Iteration: 378456526, states[0] = -87.869349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387355329, states[0] = -17.422950, states[40]= 0.001605
Saving checkpoint... 
Iteration: 396667938, states[0] = 5.280120, states[40]= 0.007057
Saving checkpoint... 
Iteration: 406074697, states[0] = -87.459529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415274616, states[0] = -87.835420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424478166, states[0] = 18.522097, states[40]= 0.012005
Saving checkpoint... 
Iteration: 433742970, states[0] = -87.658360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442960766, states[0] = 29.186278, states[40]= 0.102404
Saving checkpoint... 
Iteration: 452174631, states[0] = -6.987903, states[40]= 0.004154
Saving checkpoint... 
Iteration: 461387393, states[0] = -75.935510, states[40]= 0.000001
Saving checkpoint... 
Iteration: 470663160, states[0] = 3.085517, states[40]= 0.006674
Saving checkpoint... 
Iteration: 480029969, states[0] = -41.826265, states[40]= 0.000118
Saving checkpoint... 
Iteration: 489581697, states[0] = -87.765502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499286306, states[0] = 36.456714, states[40]= 0.089509
Saving checkpoint... 
Iteration: 508937660, states[0] = -87.852809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518754993, states[0] = -87.803939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528494438, states[0] = -0.369518, states[40]= 0.005967
Saving checkpoint... 
Iteration: 538252768, states[0] = -87.802979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547743060, states[0] = -87.767911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557499568, states[0] = -9.789209, states[40]= 0.003326
Saving checkpoint... 
Iteration: 567285405, states[0] = 24.478026, states[40]= 0.059240
Saving checkpoint... 
Iteration: 576859138, states[0] = -49.610700, states[40]= 0.000038
Saving checkpoint... 
Iteration: 585984279, states[0] = 3.669738, states[40]= 0.006780
Saving checkpoint... 
Iteration: 590693686, states[0] = -53.339949, states[40]= 0.000021
Saving checkpoint... 
Iteration: 600363104, states[0] = -58.819934, states[40]= 0.000009
Saving checkpoint... 
Iteration: 610086415, states[0] = -87.828801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619965375, states[0] = 14.732084, states[40]= 0.009109
Saving checkpoint... 
Iteration: 629716879, states[0] = -87.228857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639517820, states[0] = -47.171829, states[40]= 0.000055
Saving checkpoint... 
Iteration: 649368562, states[0] = -75.885918, states[40]= 0.000001
Saving checkpoint... 
Iteration: 659237723, states[0] = -87.791978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669062384, states[0] = -87.758814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678936363, states[0] = 31.243087, states[40]= 0.104678
Saving checkpoint... 
Iteration: 688643446, states[0] = 1.206298, states[40]= 0.006310
Saving checkpoint... 
Iteration: 698359594, states[0] = -68.850293, states[40]= 0.000002
Saving checkpoint... 
Iteration: 707883149, states[0] = -87.677827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716820432, states[0] = -14.627452, states[40]= 0.002114
Saving checkpoint... 
Iteration: 726189114, states[0] = -67.112023, states[40]= 0.000002
Saving checkpoint... 
Iteration: 735799028, states[0] = 6.593388, states[40]= 0.007276
Saving checkpoint... 
Iteration: 745459885, states[0] = 10.149326, states[40]= 0.007895
Saving checkpoint... 
Iteration: 755173762, states[0] = -48.362617, states[40]= 0.000046
Saving checkpoint... 
Iteration: 765009288, states[0] = -52.908066, states[40]= 0.000023
Saving checkpoint... 
Iteration: 774747422, states[0] = -87.861182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784427769, states[0] = 27.114336, states[40]= 0.091088
Saving checkpoint... 
Iteration: 794060276, states[0] = -87.801785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803819997, states[0] = -26.496064, states[40]= 0.000702
Saving checkpoint... 
Iteration: 813503067, states[0] = -50.935759, states[40]= 0.000031
Saving checkpoint... 
Iteration: 823229965, states[0] = -87.822484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832978030, states[0] = -18.288466, states[40]= 0.001475
Saving checkpoint... 
Iteration: 842622701, states[0] = 5.791032, states[40]= 0.007143
Saving checkpoint... 
Iteration: 844053213, states[0] = -87.794060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846077151, states[0] = -87.870787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846687351, states[0] = -83.376992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850062141, states[0] = -87.827498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850663974, states[0] = -48.024257, states[40]= 0.000048
Saving checkpoint... 
Iteration: 860191778, states[0] = -86.819898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869724656, states[0] = -87.820217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879351003, states[0] = -83.634349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888977754, states[0] = -25.939198, states[40]= 0.000738
Saving checkpoint... 
Iteration: 898779472, states[0] = 9.025799, states[40]= 0.007688
Saving checkpoint... 
Iteration: 908523088, states[0] = -87.327480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915918997, states[0] = 23.362906, states[40]= 0.042402
Saving checkpoint... 
Iteration: 925456437, states[0] = -2.111582, states[40]= 0.005543
Saving checkpoint... 
Iteration: 935168013, states[0] = -66.781041, states[40]= 0.000003
Saving checkpoint... 
Iteration: 944836443, states[0] = -71.418576, states[40]= 0.000001
Saving checkpoint... 
Iteration: 954521446, states[0] = -87.560307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964110028, states[0] = 6.204010, states[40]= 0.007211
Saving checkpoint... 
Iteration: 973818186, states[0] = -47.824552, states[40]= 0.000050
Saving checkpoint... 
Iteration: 983450237, states[0] = -1.691961, states[40]= 0.005650
Saving checkpoint... 
Iteration: 993162373, states[0] = -67.046191, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1002876803, states[0] = -87.815989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012643018, states[0] = -41.334797, states[40]= 0.000127
Saving checkpoint... 
Iteration: 1022376620, states[0] = -87.821965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032209115, states[0] = -87.822433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042028323, states[0] = -87.773376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051261072, states[0] = 11.221504, states[40]= 0.008112
Saving checkpoint... 
Iteration: 1060664893, states[0] = -82.168258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070436797, states[0] = 2.834676, states[40]= 0.006628
Saving checkpoint... 
Iteration: 1080134310, states[0] = -38.601929, states[40]= 0.000183
Saving checkpoint... 
Iteration: 1089749768, states[0] = 15.891657, states[40]= 0.009641
Saving checkpoint... 
Iteration: 1099441058, states[0] = -4.356644, states[40]= 0.004932
Saving checkpoint... 
Iteration: 1109152512, states[0] = -69.991995, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1118727966, states[0] = 26.702389, states[40]= 0.087447
Saving checkpoint... 
Iteration: 1128405307, states[0] = 19.752709, states[40]= 0.014475
Saving checkpoint... 
Iteration: 1138065526, states[0] = 22.316173, states[40]= 0.029350
Saving checkpoint... 
Iteration: 1147773527, states[0] = -9.328381, states[40]= 0.003459
Saving checkpoint... 
Iteration: 1157660926, states[0] = -86.481907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167385548, states[0] = 39.546964, states[40]= 0.073620
Saving checkpoint... 
Iteration: 1177178822, states[0] = -87.761243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186864282, states[0] = -87.835333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196532162, states[0] = -87.842112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206321451, states[0] = -85.941608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215973925, states[0] = -67.887625, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1225552793, states[0] = 24.559054, states[40]= 0.060467
Saving checkpoint... 
Iteration: 1235161808, states[0] = -87.630243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244864597, states[0] = -87.853810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254574177, states[0] = 11.149117, states[40]= 0.008097
Saving checkpoint... 
Iteration: 1264283072, states[0] = -39.319133, states[40]= 0.000167
Saving checkpoint... 
Iteration: 1273827805, states[0] = -87.697979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283469616, states[0] = -72.069927, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1293067117, states[0] = 13.250334, states[40]= 0.008611
Saving checkpoint... 
Iteration: 1302708761, states[0] = 27.922378, states[40]= 0.096843
Saving checkpoint... 
Iteration: 1312393190, states[0] = 16.451338, states[40]= 0.009973
Saving checkpoint... 
Iteration: 1321998920, states[0] = -87.767024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331464073, states[0] = -70.781301, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1341117994, states[0] = -52.413364, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1350901350, states[0] = 8.714514, states[40]= 0.007633
Saving checkpoint... 
Iteration: 1360584998, states[0] = -8.559551, states[40]= 0.003684
Saving checkpoint... 
Iteration: 1370300200, states[0] = -81.675475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379869384, states[0] = 25.694516, states[40]= 0.076307
Saving checkpoint... 
Iteration: 1389437801, states[0] = -40.126440, states[40]= 0.000149
Saving checkpoint... 
Iteration: 1398880069, states[0] = 18.853511, states[40]= 0.012529
Saving checkpoint... 
Iteration: 1408283870, states[0] = -61.203131, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1417592564, states[0] = -27.373509, states[40]= 0.000648
Saving checkpoint... 
Iteration: 1427090051, states[0] = -25.149879, states[40]= 0.000792
Saving checkpoint... 
Iteration: 1436408069, states[0] = -5.188897, states[40]= 0.004690
Saving checkpoint... 
Iteration: 1445750541, states[0] = -18.956214, states[40]= 0.001384
Saving checkpoint... 
Iteration: 1455145978, states[0] = -87.729615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464517177, states[0] = -87.875135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474038988, states[0] = 18.970732, states[40]= 0.012737
Saving checkpoint... 
Iteration: 1483490460, states[0] = -87.797896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492898147, states[0] = -0.528089, states[40]= 0.005931
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.758456
 - CaMKt in component CaMK (millimolar): 0.037442
 - cass in component intracellular_ions (millimolar): 0.000114
 - nai in component intracellular_ions (millimolar): 6.856109
 - nass in component intracellular_ions (millimolar): 6.856253
 - ki in component intracellular_ions (millimolar): 145.077139
 - kss in component intracellular_ions (millimolar): 145.077107
 - cansr in component intracellular_ions (millimolar): 1.564930
 - cajsr in component intracellular_ions (millimolar): 1.158744
 - cai in component intracellular_ions (millimolar): 0.000110
 - m in component INa (dimensionless): 0.007433
 - hf in component INa (dimensionless): 0.693965
 - hs in component INa (dimensionless): 0.693738
 - j in component INa (dimensionless): 0.683698
 - hsp in component INa (dimensionless): 0.449147
 - jp in component INa (dimensionless): 0.657908
 - mL in component INaL (dimensionless): 0.000193
 - hL in component INaL (dimensionless): 0.296737
 - hLp in component INaL (dimensionless): 0.138430
 - a in component Ito (dimensionless): 0.001009
 - iF in component Ito (dimensionless): 0.999544
 - iS in component Ito (dimensionless): 0.177591
 - ap in component Ito (dimensionless): 0.000514
 - iFp in component Ito (dimensionless): 0.999544
 - iSp in component Ito (dimensionless): 0.214785
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.803377
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.966145
 - jca in component ICaL (dimensionless): 0.949100
 - ffp in component ICaL (dimensionless): 0.999876
 - fcafp in component ICaL (dimensionless): 0.999992
 - nca in component ICaL (dimensionless): 0.008978
 - xrf in component IKr (dimensionless): 0.028680
 - xrs in component IKr (dimensionless): 0.799467
 - xs1 in component IKs (dimensionless): 0.456638
 - xs2 in component IKs (dimensionless): 0.001124
 - xk1 in component IK1 (dimensionless): 0.996796
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
03:05:44 (335708): called boinc_finish(0)

</stderr_txt>
]]>


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