𝕏

Task 55150253

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-Schmidt_8000-conf_898_0
Workunit 26188752
Created 28 Jun 2024, 5:36:50 UTC
Sent 28 Jun 2024, 18:59:13 UTC
Report deadline 1 Jul 2024, 18:59:13 UTC
Received 29 Jun 2024, 6:56:04 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230524
Run time 2 hours 16 min 32 sec
CPU time 2 hours 12 min
Validate state Valid
Credit 43.29
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.66 MB
Peak swap size 2.35 GB
Peak disk usage 2.47 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Schmidt_8000-conf_898.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Schmidt_8000-conf_898_0_r272196950_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Schmidt_8000-conf_898_0_r272196950_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 107.056758
     * GNaL_b in INaL: 0.007282
     * Gto_b in Ito: 0.091798
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030212
     * GKs_b in IKs: 0.002075
     * GK1_b in IK1: 0.157401
     * Gncx_b in INaCa_i: 0.000974
     * Pnak_b in INaK: 69.748735
     * GKb_b in IKb: 0.003866
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.021824
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 375.000000
     * CL_0 in membrane: 8000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1496000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11132741, states[0] = -84.049269, states[40]= 0.000001
Saving checkpoint... 
Iteration: 22257728, states[0] = -83.918954, states[40]= 0.000001
Saving checkpoint... 
Iteration: 33426398, states[0] = -83.862308, states[40]= 0.000001
Saving checkpoint... 
Iteration: 44564377, states[0] = -83.820890, states[40]= 0.000001
Saving checkpoint... 
Iteration: 55725093, states[0] = -83.764456, states[40]= 0.000001
Saving checkpoint... 
Iteration: 66871570, states[0] = -83.749343, states[40]= 0.000001
Saving checkpoint... 
Iteration: 78007428, states[0] = -83.746215, states[40]= 0.000001
Saving checkpoint... 
Iteration: 89166075, states[0] = -83.764638, states[40]= 0.000001
Saving checkpoint... 
Iteration: 100428654, states[0] = -83.661048, states[40]= 0.000001
Saving checkpoint... 
Iteration: 111663312, states[0] = -83.711586, states[40]= 0.000001
Saving checkpoint... 
Iteration: 122864729, states[0] = -83.711137, states[40]= 0.000001
Saving checkpoint... 
Iteration: 134050854, states[0] = -83.717347, states[40]= 0.000001
Saving checkpoint... 
Iteration: 145116978, states[0] = -83.746605, states[40]= 0.000001
Saving checkpoint... 
Iteration: 156349442, states[0] = -83.508636, states[40]= 0.000001
Saving checkpoint... 
Iteration: 167564718, states[0] = -83.699907, states[40]= 0.000001
Saving checkpoint... 
Iteration: 178797211, states[0] = -83.702547, states[40]= 0.000001
Saving checkpoint... 
Iteration: 189867488, states[0] = -83.714208, states[40]= 0.000001
Saving checkpoint... 
Iteration: 201062795, states[0] = -83.744327, states[40]= 0.000001
Saving checkpoint... 
Iteration: 212315998, states[0] = -83.406693, states[40]= 0.000001
Saving checkpoint... 
Iteration: 223544308, states[0] = -83.696891, states[40]= 0.000001
Saving checkpoint... 
Iteration: 234756132, states[0] = -83.700493, states[40]= 0.000001
Saving checkpoint... 
Iteration: 245920475, states[0] = -83.711240, states[40]= 0.000001
Saving checkpoint... 
Iteration: 257144122, states[0] = -83.738690, states[40]= 0.000001
Saving checkpoint... 
Iteration: 268374680, states[0] = -83.558986, states[40]= 0.000001
Saving checkpoint... 
Iteration: 279547954, states[0] = -83.696032, states[40]= 0.000001
Saving checkpoint... 
Iteration: 290763720, states[0] = -83.699773, states[40]= 0.000001
Saving checkpoint... 
Iteration: 301802255, states[0] = -83.713427, states[40]= 0.000001
Saving checkpoint... 
Iteration: 312981838, states[0] = -83.746767, states[40]= 0.000001
Saving checkpoint... 
Iteration: 324167866, states[0] = -40.328052, states[40]= 0.000361
Saving checkpoint... 
Iteration: 335360340, states[0] = -83.696387, states[40]= 0.000001
Saving checkpoint... 
Iteration: 346592329, states[0] = -83.700956, states[40]= 0.000001
Saving checkpoint... 
Iteration: 357771473, states[0] = -83.714007, states[40]= 0.000001
Saving checkpoint... 
Iteration: 368948595, states[0] = -83.748240, states[40]= 0.000001
Saving checkpoint... 
Iteration: 380159687, states[0] = -34.202519, states[40]= 0.000708
Saving checkpoint... 
Iteration: 391341603, states[0] = -83.696325, states[40]= 0.000001
Saving checkpoint... 
Iteration: 402557960, states[0] = -83.701156, states[40]= 0.000001
Saving checkpoint... 
Iteration: 413732495, states[0] = -83.714923, states[40]= 0.000001
Saving checkpoint... 
Iteration: 424947501, states[0] = -83.748188, states[40]= 0.000001
Saving checkpoint... 
Iteration: 436117651, states[0] = -3.098662, states[40]= 0.001364
Saving checkpoint... 
Iteration: 447307263, states[0] = -83.696363, states[40]= 0.000001
Saving checkpoint... 
Iteration: 458353113, states[0] = -83.703282, states[40]= 0.000001
Saving checkpoint... 
Iteration: 469501698, states[0] = -83.722080, states[40]= 0.000001
Saving checkpoint... 
Iteration: 480683277, states[0] = -83.750115, states[40]= 0.000001
Saving checkpoint... 
Iteration: 491901662, states[0] = -83.694559, states[40]= 0.000001
Saving checkpoint... 
Iteration: 503130277, states[0] = -83.697052, states[40]= 0.000001
Saving checkpoint... 
Iteration: 514252414, states[0] = -83.704513, states[40]= 0.000001
Saving checkpoint... 
Iteration: 525453040, states[0] = -83.723809, states[40]= 0.000001
Saving checkpoint... 
Iteration: 536658194, states[0] = -83.747685, states[40]= 0.000001
Saving checkpoint... 
Iteration: 547818962, states[0] = -83.694657, states[40]= 0.000001
Saving checkpoint... 
Iteration: 559016072, states[0] = -83.697559, states[40]= 0.000001
Saving checkpoint... 
Iteration: 570118400, states[0] = -83.706461, states[40]= 0.000001
Saving checkpoint... 
Iteration: 581181379, states[0] = -83.735865, states[40]= 0.000001
Saving checkpoint... 
Iteration: 592387212, states[0] = -83.581071, states[40]= 0.000001
Saving checkpoint... 
Iteration: 603566225, states[0] = -83.695236, states[40]= 0.000001
Saving checkpoint... 
Iteration: 614596986, states[0] = -83.700467, states[40]= 0.000001
Saving checkpoint... 
Iteration: 625743954, states[0] = -83.714294, states[40]= 0.000001
Saving checkpoint... 
Iteration: 636945008, states[0] = -83.747989, states[40]= 0.000001
Saving checkpoint... 
Iteration: 648110740, states[0] = 0.662301, states[40]= 0.001215
Saving checkpoint... 
Iteration: 659313522, states[0] = -83.696021, states[40]= 0.000001
Saving checkpoint... 
Iteration: 667298314, states[0] = -83.696069, states[40]= 0.000001
Saving checkpoint... 
Iteration: 678411041, states[0] = -83.702269, states[40]= 0.000001
Saving checkpoint... 
Iteration: 689764143, states[0] = -83.713669, states[40]= 0.000001
Saving checkpoint... 
Iteration: 701110258, states[0] = -83.739363, states[40]= 0.000001
Saving checkpoint... 
Iteration: 712415030, states[0] = -83.622904, states[40]= 0.000001
Saving checkpoint... 
Iteration: 723724563, states[0] = -83.694624, states[40]= 0.000001
Saving checkpoint... 
Iteration: 735062548, states[0] = -83.697049, states[40]= 0.000001
Saving checkpoint... 
Iteration: 746381979, states[0] = -83.702506, states[40]= 0.000001
Saving checkpoint... 
Iteration: 757702060, states[0] = -83.715245, states[40]= 0.000001
Saving checkpoint... 
Iteration: 769061946, states[0] = -83.741814, states[40]= 0.000001
Saving checkpoint... 
Iteration: 780278539, states[0] = -83.251763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791429539, states[0] = -83.695398, states[40]= 0.000001
Saving checkpoint... 
Iteration: 802667958, states[0] = -83.699572, states[40]= 0.000001
Saving checkpoint... 
Iteration: 813900387, states[0] = -83.710244, states[40]= 0.000001
Saving checkpoint... 
Iteration: 825223466, states[0] = -83.733410, states[40]= 0.000001
Saving checkpoint... 
Iteration: 836535807, states[0] = -83.717872, states[40]= 0.000001
Saving checkpoint... 
Iteration: 848409600, states[0] = -83.615353, states[40]= 0.000001
Saving checkpoint... 
Iteration: 860320675, states[0] = -83.419994, states[40]= 0.000001
Saving checkpoint... 
Iteration: 872291119, states[0] = -83.308494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884245253, states[0] = -83.075352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896215618, states[0] = -80.176384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908196633, states[0] = -63.383160, states[40]= 0.000012
Saving checkpoint... 
Iteration: 920153413, states[0] = -29.554683, states[40]= 0.000996
Saving checkpoint... 
Iteration: 932101560, states[0] = 4.918237, states[40]= 0.000886
Saving checkpoint... 
Iteration: 944056869, states[0] = 22.044394, states[40]= 0.000080
Saving checkpoint... 
Iteration: 955356534, states[0] = -83.695419, states[40]= 0.000001
Saving checkpoint... 
Iteration: 966672348, states[0] = -83.699294, states[40]= 0.000001
Saving checkpoint... 
Iteration: 977921928, states[0] = -83.709540, states[40]= 0.000001
Saving checkpoint... 
Iteration: 989228309, states[0] = -83.732933, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1000355357, states[0] = -83.516316, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1011575845, states[0] = -83.694605, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1022658991, states[0] = -83.699323, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1033766406, states[0] = -83.713104, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1044860465, states[0] = -83.750879, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1055929681, states[0] = -83.693666, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1067042585, states[0] = -83.696665, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1078159871, states[0] = -83.705047, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1089292376, states[0] = -83.729751, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1100400206, states[0] = -83.601332, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1111388851, states[0] = -83.695070, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1122496972, states[0] = -83.700684, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1133613289, states[0] = -83.717333, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1144601160, states[0] = -83.737678, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1155659183, states[0] = -83.694157, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1166703696, states[0] = -83.698744, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1177832034, states[0] = -83.711264, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1188914577, states[0] = -83.748571, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1200054609, states[0] = 22.816646, states[40]= 0.000069
Saving checkpoint... 
Iteration: 1211185610, states[0] = -83.695747, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1222317289, states[0] = -83.702602, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1233395132, states[0] = -83.725068, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1244556048, states[0] = -83.725016, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1255713065, states[0] = -83.693868, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1266708773, states[0] = -83.698556, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1277838745, states[0] = -83.710958, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1288979689, states[0] = -83.745333, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1300110919, states[0] = 0.573054, states[40]= 0.001221
Saving checkpoint... 
Iteration: 1311268246, states[0] = -83.695241, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1322379868, states[0] = -83.701682, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1333532157, states[0] = -83.719726, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1344648467, states[0] = -83.745354, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1355743185, states[0] = -83.693644, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1366869911, states[0] = -83.697245, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1377951781, states[0] = -83.708330, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1388768145, states[0] = -83.751911, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1399886304, states[0] = -83.693250, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1410972751, states[0] = -83.696546, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1421975954, states[0] = -83.707780, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1433027843, states[0] = -83.742639, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1444159312, states[0] = -33.920344, states[40]= 0.000726
Saving checkpoint... 
Iteration: 1455241396, states[0] = -83.695141, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1466339128, states[0] = -83.701966, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1477385698, states[0] = -83.725099, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1488550457, states[0] = -83.722671, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1499563066, states[0] = -83.693923, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -83.568856
 - CaMKt in component CaMK (millimolar): 0.000891
 - cass in component intracellular_ions (millimolar): 0.000093
 - nai in component intracellular_ions (millimolar): 6.128179
 - nass in component intracellular_ions (millimolar): 6.128290
 - ki in component intracellular_ions (millimolar): 145.771152
 - kss in component intracellular_ions (millimolar): 145.771142
 - cansr in component intracellular_ions (millimolar): 1.669586
 - cajsr in component intracellular_ions (millimolar): 1.669588
 - cai in component intracellular_ions (millimolar): 0.000096
 - m in component INa (dimensionless): 0.011318
 - hf in component INa (dimensionless): 0.532524
 - hs in component INa (dimensionless): 0.532524
 - j in component INa (dimensionless): 0.532525
 - hsp in component INa (dimensionless): 0.291430
 - jp in component INa (dimensionless): 0.532525
 - mL in component INaL (dimensionless): 0.000427
 - hL in component INaL (dimensionless): 0.372129
 - hLp in component INaL (dimensionless): 0.205707
 - a in component Ito (dimensionless): 0.001338
 - iF in component Ito (dimensionless): 0.999053
 - iS in component Ito (dimensionless): 0.998844
 - ap in component Ito (dimensionless): 0.000682
 - iFp in component Ito (dimensionless): 0.999053
 - iSp in component Ito (dimensionless): 0.998968
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999935
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003828
 - xrf in component IKr (dimensionless): 0.000015
 - xrs in component IKr (dimensionless): 0.001074
 - xs1 in component IKs (dimensionless): 0.006175
 - xs2 in component IKs (dimensionless): 0.000312
 - xk1 in component IK1 (dimensionless): 0.997018
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
22:50:55 (71703): called boinc_finish(0)

</stderr_txt>
]]>


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