𝕏

Task 55145714

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_1000-conf_94_1
Workunit 26186483
Created 28 Jun 2024, 5:34:44 UTC
Sent 28 Jun 2024, 18:15:46 UTC
Report deadline 1 Jul 2024, 18:15:46 UTC
Received 29 Jun 2024, 15:03:56 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 2 hours 57 min 20 sec
CPU time 1 hours 26 min 22 sec
Validate state Valid
Credit 43.45
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.89 MB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_1000-conf_94.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_1000-conf_94_1_r427335852_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pieske_1000-conf_94_1_r427335852_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 113.400997
     * GNaL_b in INaL: 0.007580
     * Gto_b in Ito: 0.085781
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033599
     * GKs_b in IKs: 0.002061
     * GK1_b in IK1: 0.150814
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 68.959397
     * GKb_b in IKb: 0.003702
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019491
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8782158, states[0] = -86.842475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17621155, states[0] = -47.510486, states[40]= 0.000037
Saving checkpoint... 
Iteration: 26541216, states[0] = 14.687085, states[40]= 0.004892
Saving checkpoint... 
Iteration: 34516683, states[0] = 22.229057, states[40]= 0.012041
Saving checkpoint... 
Iteration: 43066176, states[0] = 4.070622, states[40]= 0.004590
Saving checkpoint... 
Iteration: 51715036, states[0] = -86.608186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59695668, states[0] = -86.557989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68792837, states[0] = -86.709521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77820988, states[0] = -86.728934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87003282, states[0] = 31.869170, states[40]= 0.168040
Saving checkpoint... 
Iteration: 95649392, states[0] = -76.529278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104165368, states[0] = -86.110900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113609772, states[0] = -31.631944, states[40]= 0.000363
Saving checkpoint... 
Iteration: 121774605, states[0] = -86.671273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130910407, states[0] = -86.760757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139346690, states[0] = -86.731771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147984161, states[0] = -86.776102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155970001, states[0] = -86.773301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163801426, states[0] = -86.696443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173201692, states[0] = -86.542626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180748359, states[0] = -86.631018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189164809, states[0] = -86.011296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197985345, states[0] = -86.774571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206438682, states[0] = -86.765404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214715716, states[0] = -86.571470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223099831, states[0] = -21.426265, states[40]= 0.000839
Saving checkpoint... 
Iteration: 230648950, states[0] = -75.378140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239463344, states[0] = -86.770445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248100057, states[0] = -21.649468, states[40]= 0.000826
Saving checkpoint... 
Iteration: 255514701, states[0] = 22.818781, states[40]= 0.016774
Saving checkpoint... 
Iteration: 263476355, states[0] = -86.772666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271713874, states[0] = -86.567402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281126926, states[0] = -49.092746, states[40]= 0.000030
Saving checkpoint... 
Iteration: 289799232, states[0] = -86.692949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297648469, states[0] = -74.739965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306040817, states[0] = 15.636072, states[40]= 0.004896
Saving checkpoint... 
Iteration: 314685308, states[0] = -86.503945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323380683, states[0] = -86.746022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331300326, states[0] = -86.693928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340018086, states[0] = 22.363809, states[40]= 0.010199
Saving checkpoint... 
Iteration: 348130012, states[0] = -52.448564, states[40]= 0.000017
Saving checkpoint... 
Iteration: 356427774, states[0] = -86.762114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365349437, states[0] = -86.730410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374303416, states[0] = -86.696746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383227453, states[0] = -86.594045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392169426, states[0] = -86.331605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400248582, states[0] = -86.630363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409396110, states[0] = -86.752058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417991603, states[0] = -86.774826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427293283, states[0] = -86.686994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435929133, states[0] = -86.762415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444159796, states[0] = -84.908438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452926386, states[0] = -86.761660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462522453, states[0] = 21.514454, states[40]= 0.007103
Saving checkpoint... 
Iteration: 471277263, states[0] = -86.669458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479514815, states[0] = 22.806541, states[40]= 0.016437
Saving checkpoint... 
Iteration: 488342101, states[0] = -86.725918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496188169, states[0] = -86.511077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503829080, states[0] = -86.717278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512275187, states[0] = -86.666948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520368657, states[0] = -86.740423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528902265, states[0] = -86.754163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538411443, states[0] = -86.757195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547054133, states[0] = 10.278796, states[40]= 0.004766
Saving checkpoint... 
Iteration: 557637705, states[0] = -61.122283, states[40]= 0.000004
Saving checkpoint... 
Iteration: 565449263, states[0] = -86.767185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573679406, states[0] = -86.482978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582313552, states[0] = -86.705370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590539507, states[0] = 16.132373, states[40]= 0.004932
Saving checkpoint... 
Iteration: 598414590, states[0] = -86.758131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607215588, states[0] = -86.570606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615204114, states[0] = -86.546493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623097503, states[0] = -19.067441, states[40]= 0.001003
Saving checkpoint... 
Iteration: 631739243, states[0] = -86.614956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639972303, states[0] = -86.771626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648985231, states[0] = -86.773718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658708560, states[0] = -86.555952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666874969, states[0] = -86.743249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674472001, states[0] = -86.771548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683159768, states[0] = -84.897922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692349875, states[0] = -86.730416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700999084, states[0] = -86.775636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708530099, states[0] = 19.416868, states[40]= 0.005500
Saving checkpoint... 
Iteration: 716971656, states[0] = -86.771456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725065904, states[0] = 4.950752, states[40]= 0.004623
Saving checkpoint... 
Iteration: 733258244, states[0] = -86.644535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741016992, states[0] = 22.529961, states[40]= 0.011697
Saving checkpoint... 
Iteration: 750045216, states[0] = 13.924103, states[40]= 0.004819
Saving checkpoint... 
Iteration: 759056787, states[0] = 9.141960, states[40]= 0.004753
Saving checkpoint... 
Iteration: 767512354, states[0] = 23.059975, states[40]= 0.026832
Saving checkpoint... 
Iteration: 775312097, states[0] = -86.704019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783652344, states[0] = -79.511025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792322651, states[0] = -86.712377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800441316, states[0] = -86.765204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809211143, states[0] = -86.561272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816870785, states[0] = -86.741212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824799996, states[0] = -86.693240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833841274, states[0] = -86.725146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842086909, states[0] = -8.765419, states[40]= 0.002573
Saving checkpoint... 
Iteration: 850371263, states[0] = -86.741411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859915524, states[0] = -86.758223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869544852, states[0] = 14.068194, states[40]= 0.004823
Saving checkpoint... 
Iteration: 877489306, states[0] = -86.774154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885648937, states[0] = -75.348266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895480911, states[0] = -86.772865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903953903, states[0] = -86.767925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912411939, states[0] = -86.757074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920274352, states[0] = -86.665632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928392297, states[0] = -86.750246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936572405, states[0] = 1.541098, states[40]= 0.004366
Saving checkpoint... 
Iteration: 945291330, states[0] = -86.684620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953810245, states[0] = -86.702325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962950422, states[0] = -86.767142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971664365, states[0] = -85.951933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981039529, states[0] = 16.124204, states[40]= 0.004931
Saving checkpoint... 
Iteration: 990503670, states[0] = 30.328517, states[40]= 0.168172
Saving checkpoint... 
Iteration: 998893290, states[0] = -86.750570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008152164, states[0] = -79.309678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016175590, states[0] = -86.456581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024685633, states[0] = -86.504268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032590374, states[0] = -11.978720, states[40]= 0.001935
Saving checkpoint... 
Iteration: 1041005004, states[0] = 26.735527, states[40]= 0.147290
Saving checkpoint... 
Iteration: 1049421801, states[0] = -86.759935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057383740, states[0] = -86.746750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065196756, states[0] = -86.530144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073845543, states[0] = -86.727586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082995070, states[0] = -86.774816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092479520, states[0] = -86.772497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100744582, states[0] = -86.623472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108832635, states[0] = -86.719295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116766036, states[0] = -86.654941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126027217, states[0] = 20.285073, states[40]= 0.005877
Saving checkpoint... 
Iteration: 1134560521, states[0] = 7.487107, states[40]= 0.004720
Saving checkpoint... 
Iteration: 1142438863, states[0] = -86.764364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151318919, states[0] = -86.709250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159725985, states[0] = -86.590689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168446478, states[0] = -86.766121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177918729, states[0] = -86.758947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186608900, states[0] = -30.526802, states[40]= 0.000409
Saving checkpoint... 
Iteration: 1196581549, states[0] = -4.369818, states[40]= 0.003485
Saving checkpoint... 
Iteration: 1204788740, states[0] = -86.681731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214402349, states[0] = -86.753684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222666414, states[0] = -86.161298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231137560, states[0] = -60.951591, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1239935817, states[0] = -86.763543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247652124, states[0] = -79.264103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256245274, states[0] = -86.624474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264832623, states[0] = -86.719171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272993010, states[0] = -86.774390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281672753, states[0] = -86.419204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290382733, states[0] = -86.746158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298513666, states[0] = 22.929087, states[40]= 0.020397
Saving checkpoint... 
Iteration: 1306925130, states[0] = -86.760682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315697685, states[0] = -86.531996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323579838, states[0] = -3.126498, states[40]= 0.003716
Saving checkpoint... 
Iteration: 1331881300, states[0] = -86.745524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340006643, states[0] = 24.663513, states[40]= 0.105476
Saving checkpoint... 
Iteration: 1349437919, states[0] = -86.763981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358302999, states[0] = -86.695630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366097139, states[0] = -18.699355, states[40]= 0.001034
Saving checkpoint... 
Iteration: 1374079465, states[0] = -2.865084, states[40]= 0.003762
Saving checkpoint... 
Iteration: 1382165564, states[0] = -86.086437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391884885, states[0] = -86.746973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399898295, states[0] = -86.752117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408140018, states[0] = -63.874492, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1417086252, states[0] = -8.185682, states[40]= 0.002696
Saving checkpoint... 
Iteration: 1425286147, states[0] = -86.678797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434552005, states[0] = 11.171149, states[40]= 0.004775
Saving checkpoint... 
Iteration: 1442955479, states[0] = -86.767852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450540982, states[0] = 15.573600, states[40]= 0.004892
Saving checkpoint... 
Iteration: 1459035808, states[0] = 17.489899, states[40]= 0.005078
Saving checkpoint... 
Iteration: 1468291972, states[0] = -86.684888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478137705, states[0] = -61.120848, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1486617131, states[0] = -38.818544, states[40]= 0.000142
Saving checkpoint... 
Iteration: 1495049645, states[0] = 12.143073, states[40]= 0.004785
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.651041
 - CaMKt in component CaMK (millimolar): 0.006874
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.519814
 - nass in component intracellular_ions (millimolar): 6.519873
 - ki in component intracellular_ions (millimolar): 145.461370
 - kss in component intracellular_ions (millimolar): 145.461350
 - cansr in component intracellular_ions (millimolar): 1.305324
 - cajsr in component intracellular_ions (millimolar): 1.267547
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.008308
 - hf in component INa (dimensionless): 0.654015
 - hs in component INa (dimensionless): 0.654002
 - j in component INa (dimensionless): 0.653932
 - hsp in component INa (dimensionless): 0.405602
 - jp in component INa (dimensionless): 0.653883
 - mL in component INaL (dimensionless): 0.000238
 - hL in component INaL (dimensionless): 0.459760
 - hLp in component INaL (dimensionless): 0.236128
 - a in component Ito (dimensionless): 0.001087
 - iF in component Ito (dimensionless): 0.999447
 - iS in component Ito (dimensionless): 0.577641
 - ap in component Ito (dimensionless): 0.000554
 - iFp in component Ito (dimensionless): 0.999447
 - iSp in component Ito (dimensionless): 0.631586
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935104
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999893
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001576
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.413589
 - xs1 in component IKs (dimensionless): 0.241753
 - xs2 in component IKs (dimensionless): 0.000221
 - xk1 in component IK1 (dimensionless): 0.997067
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:40:21 (2120): called boinc_finish(0)

</stderr_txt>
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